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Volumn 25, Issue 11, 2011, Pages 1579-1585

Ergosta-7,22-diene-2β,3α,9α-triol from the fruit bodies of Ganoderma lucidum induces apoptosis in human myelocytic HL-60 cells

Author keywords

Antitumor; Apoptosis; Ergosta 7,22 diene 2 ,3 , 9 triol; Ganoderma lucidum; HL 60 cells; LLC cells; Polyporaceae

Indexed keywords

3 BETA,5 ALPHA DIHYDROXY 6 BETA METHOXYERGOSTA 7,22 DIENE; 5 ALPHA,6 ALPHA EPOXY ERGOSTA 8,22 DIENE 3 BETA, 7 ALPHA DIOL; ANTINEOPLASTIC AGENT; CASPASE 3; DOXORUBICIN; ERGOSTA 7,22 DIENE 2BETA,3ALPHA,9ALPHA TRIOL; ERGOSTEROL; ERGOSTEROL PEROXIDE; GANODERIOL; GANODERIOL F; GARNODERIC ACID; GARNODERIC ACID DM; GARNODERIC ACID S; GARNODERIC ACID T Q; GARNODERIC ACID Y; GARNODERMADIOL; LUCIDADIOL; LUCIDERIC ACID; LUCIDERIC ACID A; LUCIDERIC ACID N; LUCIDUMOL; PLANT MEDICINAL PRODUCT; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROCASPASE 3; UNCLASSIFIED DRUG;

EID: 80054946852     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3447     Document Type: Article
Times cited : (26)

References (21)
  • 1
    • 0031424574 scopus 로고    scopus 로고
    • Apoptosis, cancer and cancer therapy
    • DOI 10.1016/S0960-7404(97)00015-7, PII S0960740497000157
    • Bold RJ, Termuhlen PM, McConkey DJ. 1997. Apoptosis, cancer and cancer therapy. Surg Oncol 6: 133-142. (Pubitemid 28119138)
    • (1997) Surgical Oncology , vol.6 , Issue.3 , pp. 133-142
    • Bold, R.J.1    Termuhlen, P.M.2    McConkey, D.J.3
  • 2
  • 3
    • 67649880855 scopus 로고    scopus 로고
    • Cytotoxic activities of 9,11-dehydroergosterol peroxide and ergosterol peroxide from the fermentation mycelia of Ganoderma lucidum cultivated in the medium containing leguminous plants on Hep 3B cells
    • Chen YK, Kuo YH, Chiang BH, Lo JM, Sheen LY. 2009. Cytotoxic activities of 9,11-dehydroergosterol peroxide and ergosterol peroxide from the fermentation mycelia of Ganoderma lucidum cultivated in the medium containing leguminous plants on Hep 3B cells. J Agric Food Chem 57: 5713-5719.
    • (2009) J Agric Food Chem , vol.57 , pp. 5713-5719
    • Chen, Y.K.1    Kuo, Y.H.2    Chiang, B.H.3    Lo, J.M.4    Sheen, L.Y.5
  • 4
    • 0034672470 scopus 로고    scopus 로고
    • Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells
    • Cheung WM, Hui WS, Chu PW, Chiu SW, Ip NY. 2000. Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells. FEBS Lett 486: 291-296.
    • (2000) FEBS Lett , vol.486 , pp. 291-296
    • Cheung, W.M.1    Hui, W.S.2    Chu, P.W.3    Chiu, S.W.4    Ip, N.Y.5
  • 5
    • 0031959190 scopus 로고
    • Apoptosis: A modulator of cellular homeostasis and disease states
    • De-Long MJ. 1988. Apoptosis: a modulator of cellular homeostasis and disease states. Ann NY Acad Sci 842: 82-90.
    • (1988) Ann NY Acad Sci , vol.842 , pp. 82-90
    • De-Long, M.J.1
  • 6
    • 0032885388 scopus 로고    scopus 로고
    • Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
    • DOI 10.1146/annurev.biochem.68.1.383
    • Earnshaw WC, Martins LM, Kaufman SH. 1999. Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu Rev Biochem 68: 383-424. (Pubitemid 29449198)
    • (1999) Annual Review of Biochemistry , vol.68 , pp. 383-424
    • Earnshaw, W.C.1    Martins, L.M.2    Kaufmann, S.H.3
  • 7
    • 0026486158 scopus 로고
    • Anti-tumor activity of Ganoderma lucidum, an edible mushroom, on intraperitoneally implanted Lewis lung carcinoma in synergenic mice
    • Furusawa E, Chou SC, Furusawa S, Hirazazmi A, Dang Y. 1992. Anti-tumor activity of Ganoderma lucidum, an edible mushroom, on intraperitoneally implanted Lewis lung carcinoma in synergenic mice. Phytother Res 6: 300-304.
    • (1992) Phytother Res , vol.6 , pp. 300-304
    • Furusawa, E.1    Chou, S.C.2    Furusawa, S.3    Hirazazmi, A.4    Dang, Y.5
  • 8
    • 0041853581 scopus 로고    scopus 로고
    • Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients
    • Gao Y, Zhou S, Liang W, Huang M. 2003. Effects of ganopoly (a Ganoderma lucidum polysaccharide extract) on the immune functions in advanced-stage cancer patients. Immunol Invest 32: 201.
    • (2003) Immunol Invest , vol.32 , pp. 201
    • Gao, Y.1    Zhou, S.2    Liang, W.3    Huang, M.4
  • 9
    • 47049128697 scopus 로고    scopus 로고
    • Lucidenic acid B induces apoptosis in human leukemia cells via a mitochondria-mediated pathway
    • Hsu CL, Yu YS, Yen GC. 2008. Lucidenic acid B induces apoptosis in human leukemia cells via a mitochondria-mediated pathway. J Agric Food Chem 56: 3973-3980.
    • (2008) J Agric Food Chem , vol.56 , pp. 3973-3980
    • Hsu, C.L.1    Yu, Y.S.2    Yen, G.C.3
  • 10
    • 0347026087 scopus 로고    scopus 로고
    • Lucidenic Acids P and Q, Methyl Lucidenate P, and Other Triterpenoids from the Fungus Ganoderma lucidum and their Inhibitory Effects on Epstein-Barr Virus Activation
    • DOI 10.1021/np0302293
    • Iwatsuki K, Akihisa T, Tokuda H et al. 2003. Lucidenic acids P and Q, methyl lucidenate P, and other triterpenoids from the fungus Ganoderma lucidum and their inhibitory effects on Epstein-Barr virus activation. J Nat Prod 66: 1582-1585. (Pubitemid 38036711)
    • (2003) Journal of Natural Products , vol.66 , Issue.12 , pp. 1582-1585
    • Iwatsuki, K.1    Akihisa, T.2    Tokuda, H.3    Ukiya, M.4    Oshikubo, M.5    Kimura, Y.6    Asano, T.7    Nomura, A.8    Nishino, H.9
  • 11
    • 0032963631 scopus 로고    scopus 로고
    • Beta-glucuronidase inhibitory activity and hepatoprotective effect of Ganoderma lucidum
    • Kim DH, Shim SB, Kim NJ, Jang IS. 1999. Beta-glucuronidase inhibitory activity and hepatoprotective effect of Ganoderma lucidum. Chem Pharm Bull 22: 162-164.
    • (1999) Chem Pharm Bull , vol.22 , pp. 162-164
    • Kim, D.H.1    Shim, S.B.2    Kim, N.J.3    Jang, I.S.4
  • 12
    • 0020553856 scopus 로고
    • Microassay for colorimetric estimation of complement activity in guinea pig, human and mouse serum
    • DOI 10.1016/0022-1759(83)90425-8
    • Klerx J, Beukelman CY, Dijk HV, Willers J. 1983. Microassay for colorimetric estimation of complement activity in guinea pig, human and mouse serum. J Immunol Methods 63: 215-220. (Pubitemid 13018444)
    • (1983) Journal of Immunological Methods , vol.63 , Issue.2 , pp. 215-220
    • Klerx, J.P.A.M.1    Beukelman, C.J.2    Van Dijk, H.3    Willers, J.M.N.4
  • 13
    • 77957552558 scopus 로고    scopus 로고
    • Effect of lanostane triterpenes from the fruiting bodies of Ganoderma lucidum on adipocyte differentiation in 3T3-L1 cells
    • Lee I, Kim H, Youn U et al. 2010a. Effect of lanostane triterpenes from the fruiting bodies of Ganoderma lucidum on adipocyte differentiation in 3T3-L1 cells. Planta Med 76: 1558-1563.
    • (2010) Planta Med , vol.76 , pp. 1558-1563
    • Lee, I.1    Kim, H.2    Youn, U.3
  • 14
    • 77749267995 scopus 로고    scopus 로고
    • Lanostane triterpenes from the fruiting bodies of Ganoderma lucidum and their inhibitory effects on adipocyte differentiation in 3T3-L1 Cells
    • Lee I, Seo J, Kim J et al. 2010b. Lanostane triterpenes from the fruiting bodies of Ganoderma lucidum and their inhibitory effects on adipocyte differentiation in 3T3-L1 Cells. J Nat Prod 73: 172-176.
    • (2010) J Nat Prod , vol.73 , pp. 172-176
    • Lee, I.1    Seo, J.2    Kim, J.3
  • 15
    • 0004243384 scopus 로고    scopus 로고
    • 2nd edn. Beijing Medical University Press: Beijing
    • Lin ZB. 2001. Modern research of Ganoderma lucidum, 2nd edn. Beijing Medical University Press: Beijing, 219-283.
    • (2001) Modern Research of Ganoderma Lucidum , pp. 219-283
    • Lin, Z.B.1
  • 16
    • 65349164624 scopus 로고    scopus 로고
    • Evaluation of antiproliferative activities and action mechanisms of extracts from two species of Ganoderma on tumor cell lines
    • Liu YW, Gap JL, Guan J et al. 2009. Evaluation of antiproliferative activities and action mechanisms of extracts from two species of Ganoderma on tumor cell lines. J Agric Food Chem 57: 3087-3093.
    • (2009) J Agric Food Chem , vol.57 , pp. 3087-3093
    • Liu, Y.W.1    Gap, J.L.2    Guan, J.3
  • 17
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival application to proliferation and cytotoxicity assays
    • Mosmann TJ. 1983. Rapid colorimetric assay for cellular growth and survival application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.J.1
  • 18
    • 34247185997 scopus 로고    scopus 로고
    • Daphnane diterpene esters isolated from flower buds of Daphne genkwa induce apoptosis in human myelocytic HL-60 cells and suppress tumor growth in Lewis lung carcinoma (LLC)-inoculated mouse model
    • Park BY, Min BS, Ahn KS et al. 2007. Daphnane diterpene esters isolated from flower buds of Daphne genkwa induce apoptosis in human myelocytic HL-60 cells and suppress tumor growth in Lewis lung carcinoma (LLC)-inoculated mouse model. J Ethnopharmacol 111: 496-503.
    • (2007) J Ethnopharmacol , vol.111 , pp. 496-503
    • Park, B.Y.1    Min, B.S.2    Ahn, K.S.3
  • 19
    • 0030935175 scopus 로고    scopus 로고
    • The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes
    • Wang SY, Hsu ML, Hsu HC. 1997. The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes. Int J Cancer 70: 699-705.
    • (1997) Int J Cancer , vol.70 , pp. 699-705
    • Wang, S.Y.1    Hsu, M.L.2    Hsu, H.C.3
  • 20
    • 0002017944 scopus 로고    scopus 로고
    • Medicinal properties of substances occurring in higher Basidiomycete mushrooms: Current perspective
    • review
    • Wasser SP, Weis AL. 1999. Medicinal properties of substances occurring in higher Basidiomycete mushrooms: current perspective (review). Int J Med Mush 1: 31-62.
    • (1999) Int J Med Mush , vol.1 , pp. 31-62
    • Wasser, S.P.1    Weis, A.L.2
  • 21
    • 67149099452 scopus 로고    scopus 로고
    • Inhibitory effects of Ganoderma lucidum on tumorigenesis and metastasis of human hepatoma cells in cells and animal models
    • Weng CJ, Chau CF, Yen GC et al. 2009. Inhibitory effects of Ganoderma lucidum on tumorigenesis and metastasis of human hepatoma cells in cells and animal models. J Agric Food Chem 57: 5049-5057.
    • (2009) J Agric Food Chem , vol.57 , pp. 5049-5057
    • Weng, C.J.1    Chau, C.F.2    Yen, G.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.