The diagnosis and treatment of endometrial cancer: Progress and controversies;Diagnostik und therapie des endometriumkarzinoms: Fortschritt und kontroversen

Deutsches Arzteblatt

Volumn 108, Issue 34-35, 2011, Pages 571-577

  Denschlag, Dominik ^a   Ulrich, Uwe ^b   Emons, Günter ^c  

^a Hochtaunus Kliniken   (Germany)

^b MARTIN LUTHER KRANKENHAUS   (Germany)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER DIAGNOSIS; CANCER RADIOTHERAPY; CANCER RISK; CANCER STAGING; CANCER THERAPY; ENDOMETRIUM CARCINOMA; HISTOPATHOLOGY; HUMAN; HYSTERECTOMY; LYMPHADENECTOMY; POSTMENOPAUSE; REVIEW;

ADENOCARCINOMA, CLEAR CELL; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, ENDOMETRIOID; CHEMORADIOTHERAPY, ADJUVANT; COMBINED MODALITY THERAPY; CYSTADENOMA, SEROUS; ENDOMETRIAL NEOPLASMS; EVIDENCE-BASED MEDICINE; FEMALE; HUMANS; HYSTERECTOMY; LYMPH NODE EXCISION; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; NEOPLASMS, HORMONE-DEPENDENT; SURVIVAL RATE;

EID: 80054928228     PISSN: 00121207     EISSN: 01722107     Source Type: Journal    
DOI: 10.3238/arztebl.2011.0571     Document Type: Review

References (25)

1. th edition. Berlin 2010.
2. Robert-Koch-Institut (ed.): Verbreitung von Krebserkrankungen in Deutschland. Entwicklung der Prävalenzen zwischen 1990 und 2010. Berlin 2010.
3. Kommission Uterus der Arbeitsgemeinschaft Gynäkologische Onkologie e.V. in der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe e.V. sowie in der Deutschen Krebsgesellschaft e. V. (2008). Interdisziplinä re S2k-Leitlinie für die Diagnostik und Therapie des Endometriumkarzinoms. In: Kommission Uterus der Arbeitsgemeinschaft Gynäkologische Onkologie e.V., Deutsche Gesellschaft für Gynäkologie und Geburtshilfe e.V., Deutsche Krebsge - sellschaft e.V. (eds.): Leitlinien zum Zervixkarzinom, zum Endome - triumkarzinom und zu den Trophoblasttumoren. München Wien New York; Zuckschwerdt 2008: 73-126.
4. Furness S, Roberts H, Marjoribanks J, et al.: Hormone therapy in postmenopausal women and risk of endometrial hyperplasia. Cochrane Database Systematic Reviews 2009, Issue 2. CD000402.
5. Lacey JV Jr, Sherman ME, Rush BB, et al.: Absolute risk of endometrial carcinoma during 20-year follow-up among women with endometrial hyperplasia. J Clin Oncol 2010; 28: 788-92.
6. Smith-Bindman R, Kerlikowske K, Feldstein VA, et al.: Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities. JAMA 1998; 280(17): 1510-7. (Pubitemid 28507404)
7. Suh-Burgmann E, Hung YY, Armstrong MA: Complex atypical endometrial hyperplasia. The risk of unrecognized adenocarcinoma and value of preoperative dilation and curettage. Obstet Gynecol 2009; 114: 523-9.
8. Chiva L, Lapuente F, González-Cortijo L, et al.: Sparing fertility in young patients with endometrial cancer. Gynecol Oncol 2008; 111(2 Suppl): 101-4. Epub 2008 Sep 18.
9. Palomba S, Falbo A, Mocciaro R, et al.: Laparoscopic treatment for endometrial cancer: a meta-analysis of randomized controlled trials (RCTs). Gynecol Oncol 2009; 112: 415-21.
10. Chan JK, Wu H, Cheung MK, et al.: The outcomes of 27,063 women with unstaged endometrioid uterine cancer. Gynecol Oncol 2007; 106: 282-8. (Pubitemid 47096660)
11. Smith DC, Macdonald OK, Lee CM, Gaffney DK: Survival impact of lymph node dissection in endometrial adenocarcinoma: a surveillance, epidemiology, and end results analysis. Int J Gynecol Cancer 2007; 18: 255-61. (Pubitemid 351365216)
12. Barton DP, Naik R, Herod J: Efficacy of systemic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC Trial): a randomized study. Int J Gynecol Cancer 2009; 19(8): 1465.
13. Benedetti Panici P, Basile S, Maneschi F, et al.: Systematic pelvic lymphadenectomy vs. lymphadenectomy in early-stage endometrial carcinoma: a randomized clinical trial. J Natl Cancer Inst 2008; 100(23): 1707-16.
14. Mariani A, Dowdy SC, Cliby WA, et al.: Prospective assessment of lymphatic dissemination in endometrial cancer: a paradigm shift in surgical staging. Gynecol Oncol 2008; 109(1): 11-8.
15. Todo Y, Kato H, Kaneuchi M, Watari H, Takeda M, Sakuragi N: Survival effect of para-aortic lymphadenectomy in endometrial cancer (SEPAL study): a retrospective cohort analysis. Lancet 2010; 375(9721): 1165-72.
16. Blake P, Swart AM, Orton J, Kitchener H, et al.: Adjuvant external beam radiotherapy in the treatment of endometrial cancer (MRC ASTEC and NCIC CTG EN.5 randomized trials): pooled trial results, systematic review, and meta-analysis. Lancet 2009; 373(9658): 137-46.
17. Keys HM, Roberts JA, Brunetto VL, et al.: A phase III trial of surgery with or without external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: a Gynecologic Oncology Group study. Gynecol Oncol 2004; 92(3): 744-51. (Pubitemid 38251372)
18. Creutzberg CL, van Putten WL, Koper PC, et al.: Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial. PORTEC Study Group (Post Operative Radiation Therapy in Endometrial Carcinoma). Lancet 2000; 355(9213): 1404-11.
19. Kong A, Johnson N, Cornes P, et al.: Adjuvant radiotherapy for stage I endometrial cancer. Cochrane Database Syst Rev 2007; (2): CD003916.
20. Nout RA, Smit VTHBM, Putter H, Jürgenliemk-Schulz IM, et al.: Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC- 2): an open-label, non-inferiority, randomised trial. Lancet 2010; 375(9717): 816-23.
21. Nout RA, Putter H, Jürgenliemk-Schulz IM, et al.: Quality of life after pelvic radiotherapy or vaginal brachytherapy for endometrial cancer: first results of the randomized PORTEC-2 trial. J Clin Oncol 2009; 27(21): 3547-56.
22. Martin-Hirsch P, Jarvis G, Kitchener H, Lilford R: Progestagens for endometrial cancer. Cochrane Database Syst Rev 2000 (2): CD001040.
23. Randall ME, Filiaci VL, Muss H, et al.: Randomized phase III trial of whole-abdominal irradiation versus doxorubicin and cisplatin chemotherapy in advanced endometrial carcinoma: a Gynecologic Oncology Group study. J Clin Oncol 2006; 24: 36-44. (Pubitemid 46630491)
24. Maggi R, Lissoni A, Spina F, et al.: Adjuvant chemotherapy vs radiotherapy in high-risk endometrial carcinoma: results of a randomised trial. Br J Cancer 2006; 95: 266-71. (Pubitemid 44187586)
25. Susumu N, Sagae S, Udagawa Y, Kuramoto H, Satoh S, Kudo R: Randomized phase III trial of pelvic radiotherapy versus cisplatinbased combined chemotherapy in patients with intermediate- and high-risk endometrial cancer: a Japanese Gynecologic Oncology Group study. Gynecol Oncol 2008; 10881: 226-33. (Pubitemid 350299451)