Neurodevelopmental outcomes in children with Down syndrome and congenital heart defects

American Journal of Medical Genetics, Part A

Volumn 155, Issue 11, 2011, Pages 2688-2691

  Visootsak, Jeannie ^a,b   Mahle, William T ^b   Kirshbom, Paul M ^a   Huddleston, Lillie ^a   Caron Besch, Marcia ^b   Ransom, Amy ^b   Sherman, Stephanie L ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

Atrioventricular septal defects; Down syndrome; Neurodevelopmental outcomes

Indexed keywords

ARTICLE; BRAIN DEVELOPMENT; CHILD; CHILD DEVELOPMENT; CLINICAL ARTICLE; COGNITIVE DEVELOPMENT; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DISEASE ASSOCIATION; DOWN SYNDROME; FEMALE; HEART ATRIUM SEPTUM DEFECT; HEART VENTRICLE SEPTUM DEFECT; HUMAN; LANGUAGE DEVELOPMENT; MALE; MENTAL HEALTH; MOTOR DEVELOPMENT; PATIENT ASSESSMENT; PRESCHOOL CHILD; PRIORITY JOURNAL;

CHILD, PRESCHOOL; COGNITION DISORDERS; CROSS-SECTIONAL STUDIES; DOWN SYNDROME; FEMALE; HEART; HEART DEFECTS, CONGENITAL; HUMANS; INFANT; INTELLECTUAL DISABILITY; LANGUAGE DEVELOPMENT DISORDERS; MALE; MATERNAL AGE; PATERNAL AGE; STATISTICS, NONPARAMETRIC;

EID: 80054902937     PISSN: 15524825     EISSN: 15524833     Source Type: Journal    
DOI: 10.1002/ajmg.a.34252     Document Type: Article

References (23)

1. Bayley N. 2006. Bayley scales of infant and toddler development. San Antonio, TX: Harcourt Assessment, Inc.
2. Bellinger DC, Wypij D, Kuban KC, Rappaport LA, Hickey PR, Wernovsky G, Jonas RA, Newburger JW. 1999. Developmental and neurological status of children at 4 years of age after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass. Circulation 100: 526-532.
3. Bellinger DC, Wypij D, duPlessis AJ, Rappaport LA, Jonas RA, Wernovsky G, Newburger JW. 2003. Neurodevelopmental status at eight years in children with dextro-transposition of the great arteries: The Boston Circulatory Arrest Trial. J Thorac Cardiovasc Surg 126: 1385-1396.
4. Chapman RS, Hesketh LJ. 2000. Behavioral phenotype of individuals with Down syndrome. Ment Retard Dev Disabil Res Rev 6: 84-95.
5. Dunlop KA, Mulholland HC, Casey FA, Craig B, Gladstone DJ. 2004. A ten year review of atrioventricular septal defects. Cardiol Young 14: 15-23.
6. Ferencz C, Neill CA, Boughman JA, Rubin JD, Brenner JI, Perry LW. 1989. Congenital cardiovascular malformations associated with chromosome abnormalities: An epidemiologic study. J Pediatr 114: 79-86.
7. Freeman SB, Taft LF, Dooley KJ, Allran K, Sherman SL, Hassold TJ, Khoury MJ, Saker DM. 1998. Population-based study of congenital heart defects in Down syndrome. Am J Med Genet 80: 213-217.
8. Freeman SB, Bean LH, Allen EG, Tinker SW, Locke AE, Druschel C, Hobbs CA, Romitti PA, Royle MH, Torfs CP, Dooley KL, Sherman SL. 2008. Ethnicity, sex, and the incidence of congenital heart defects: A report from the National Down Syndrome Project. Genet Med 10: 173-180.
9. Gaynor JW, Gerdes M, Zackai EH, Bernbaum J, Wernovsky G, Clancy RR, Newman MF, Saunders AM, Heagerty PJ, D'Agostino JA, McDonald-McGinn D, Nicolson SC, Spray TL, Jarvik GP. 2003. Apolipoprotein E genotype and neurodevelopmental sequelae of infant cardiac surgery. J Thorac Cardiovasc Surg 126: 1736-1745.
10. Gaynor JW, Wernovsky G, Jarvik GP, Bernbaum J, Gerdes M, Zackai E, Nord AS, Clancy RR, Nicolson SC, Spray TL. 2007. Patient characteristics are important determinants of neurodevelopmental outcome at one year of age after neonatal and infant cardiac surgery. J Thorac Cardiovasc Surg 133: 1344-1353, 1353 e 1-3.
11. Kerstann KF, Feingold E, Freeman SB, Bean LJ, Pyatt R, Tinker S, Jewel AH, Capone G, Sherman SL. 2004. Linkage disequilibrium mapping in trisomic populations: Analytical approaches and an application to congenital heart defects in Down syndrome. Genet Epidemiol 27: 240-251.
12. Kirshbom PM, Flynn TB, Clancy RR, Ittenbach RF, Hartman DM, Paridon SM, Wernovsky G, Spray TL, Gaynor JW. 2005. Late neurodevelopmental outcome after repair of total anomalous pulmonary venous connection. J Thorac Cardiovasc Surg 129: 1091-1097.
13. Loffredo CA, Hirata J, Wilson PD, Ferencz C, Lurie IW. 2001. Atrioventricular septal defects: Possible etiologic differences between complete and partial defects. Teratology 63: 87-93.
14. Mahle WT, Visconti KJ, Freier MC, Kanne SM, Hamilton WG, Sharkey AM, Chinnock RE, Jenkins KJ, Isquith PK, Burns TG, Jenkins PC. 2006. Relationship of surgical approach to neurodevelopmental outcomes in hypoplastic left heart syndrome. Pediatrics 117: e90-e97.
15. Mahle WT, Wernovsky G. 2001. Long-term developmental outcome of children with complex congenital heart disease. Clin Perinatol 28: 235-247.
16. Malec E, Mroczek T, Pajak J, Januszewska K, Zdebska E. 1999. Results of surgical treatment of congenital heart defects in children with Down's syndrome. Pediatr Cardiol 20: 351-354.
17. Mathew P, Moodie D, Sterba R, Murphy D, Rosenkranz E, Homa A. 1990. Long-term follow-up of children with Down syndrome with cardiac lesions. Clin Pediatr (Phila) 29: 569-574.
18. Miller G, Eggli KD, Contant C, Baylen BG, Myers JL. 1995. Postoperative neurologic complications after open heart surgery on young infants. Arch Pediatr Adolesc Med 149: 764-768.
19. Parker SE, Mai CT, Canfield MA, Rickard R, Wang Y, Meyer RE, Anderson P, Mason CA, Collins JS, Kirby RS, Correa A. 2010. Updated National Birth Prevalence estimates for selected birth defects in the United States, 2004-2006. Birth Defects Res A Clin Mol Teratol 88: 1008-1016.
20. Roizen NJ. 2001. Down syndrome: Progress in research. Ment Retard Dev Disabil Res Rev 7: 38-44.
21. Stoll C, Alembik Y, Dott B, Roth MP. 1998. Study of Down syndrome in 238, 942 consecutive births. Ann Genet 41: 44-51.
22. Torfs CP, Christianson RE. 1998. Anomalies in Down syndrome individuals in a large population-based registry. Am J Med Genet 77: 431-438.
23. Wells GL, Barker SE, Finley SC, Colvin EV, Finley WH. 1994. Congenital heart disease in infants with Down's syndrome. South Med J 87: 724-727.