Direct inhibition of calcineurin by caffeoyl phenylethanoid glycosides from Teucrium chamaedrys and Nepeta cataria

Journal of Ethnopharmacology

Volumn 137, Issue 3, 2011, Pages 1306-1310

  Prescott, Thomas A K ^a   Veitch, Nigel C ^a   Simmonds, Monique S J ^a  

^a ROYAL BOTANIC GARDENS   (United Kingdom)

Author keywords

Calcineurin; Lamiuside A; Teucrioside; Teupolioside; Verbascoside

Indexed keywords

ACTEOSIDE; CAFFEIC ACID; CALCINEURIN; CALMODULIN; CATNIP EXTRACT; GLYCOSIDE; LAMIUSIDE A; PLANT EXTRACT; ROSMARINIC ACID; SEPHADEX; TEUCRIOSIDE; TEUCRIUM CHAMAEDRYS EXTRACT; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CATNIP; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; GEL FILTRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOMODULATION; MEDICINAL PLANT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TEUCRIUM CHAMAEDRYS;

ANTI-INFLAMMATORY AGENTS; CAFFEIC ACIDS; CALCINEURIN; CALMODULIN; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GLUCOSIDES; GLYCOSIDES; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; NEPETA; PHENOLS; PLANT EXTRACTS; PLANT LEAVES; PLANT STEMS; PLANTS, MEDICINAL; TEUCRIUM;

LAMIACEAE; NEPETA CATARIA; TEUCRIUM CHAMAEDRYS;

EID: 80054890748     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.07.063     Document Type: Article

References (31)

1. W.I. Al-Daraji, K.R. Grant, K. Ryan, A. Saxton, and N.J. Reynolds Localization of calcineurin/NFAT in human skin and psoriasis and inhibition of calcineurin/NFAT activation in human keratinocytes by cyclosporin A Journal of Investigative Dermatology 118 2002 779 788
2. E. Bedir, R. Manyam, and I.A. Khan Neo-clerodane diterpenoids and phenylethanoid glycosides from Teucrium chamaedrys L Phytochemistry 63 2003 977 983
3. L.W. Chen, L. Egan, Z.W. Li, F.R. Greten, M.F. Kagnoff, and M. Karin The two faces of IKK and NF-kappaB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion Nature Medicine 9 2003 575 581
4. N.A. Clipstone, and G.R. Crabtree Calcineurin is a key signaling enzyme in T lymphocyte activation and the target of the immunosuppressive drugs cyclosporin A and FK506 Annals of the New York Acadamy of Sciences 696 1993 20 30
5. G.R. Crabtree Calcium, calcineurin, and the control of transcription Journal of Biological Chemistry 276 2001 2313 2316
6. M.S Cyert Calcineurin signaling in Saccharomyces cerevisiae: how yeast go crazy in response to stress Biochemical and Biophysical Research Communications 311 2003 1143 1150
7. R. Di Paola, E. Esposito, E. Mazzon, L. Riccardi, R. Caminiti, R. Dal Toso, G. Pressi, and S. Cuzzocrea Teupolioside, a phenylpropanoid glycosides of Ajuga reptans, biotechnologically produced by IRBN22 plant cell line, exerts beneficial effects on a rodent model of colitis Biochemical Pharmacology 77 2009 845 857
8. M. Grieve A modern herbal 1984 St Edmundsbury Press Bury St Edmunds
9. Y. Hashimoto, B.A. Perrino, and T.R. Soderling Identification of an autoinhibitory domain in calcineurin Journal of Biological Chemistry 265 1990 1924 1927
10. M. Hausmann, F. Obermeier, D.H. Paper, K. Balan, N. Dunger, K. Menzel, W. Falk, J. Schoelmerich, H. Herfarth, and G. Rogler In vivo treatment with the herbal phenylethanoid acteoside ameliorates intestinal inflammation in dextran sulphate sodium-induced colitis Clinical and Experimental Immunology 148 2007 373 381
11. K. Heusler, and A. Pletscher The controversial early history of cyclosporin Swiss Medical Weekly 131 2001 299 302
12. N. Ito, T. Nihei, R. Kakuda, Y. Yaoita, and M. Kikuchi Five new phenylethanoid glycosides from the whole plants of Lamium purpureum L Chemical and Pharmaceutical Bulletin 54 2006 1705 1708
13. H. Jiang, and L. Chess An integrated view of suppressor T cell subsets in immunoregulation Journal of Clinical Investigation 114 2004 1198 1208
14. 2+-dependent pathways of T-cell antigen receptor-mediated signaling by inhibiting the PLC-gamma 1 and Itk activity Blood 101 2003 3534 3542
15. K. Kato, Y. Koshihara, and S. Murota Contribution of lipoxygenase metabolites to IL-2 production in the early phase of lymphocyte activation Prostaglandins, Leukotrienes and Medicine 22 1986 301 311
16. C.E. Lampropoulos, and D.P. D'Cruz Topical calcineurin inhibitors in systemic lupus erythematosus Therapeutics and Clinical Risk Management 6 2010 95 101
17. S. Lewis-Jones, and M.A. Mugglestone Management of atopic eczema in children aged up to 12 years: summary of NICE guidance British Medical Journal 335 2007 1263 1264
18. N. Marquez, R. Sancho, A. Macho, M.A. Calzado, B.L. Fiebich, and E. Munoz Caffeic acid phenethyl ester inhibits T-cell activation by targeting both nuclear factor of activated T-cells and NF-kappaB transcription factors The Journal of Pharmacology and Experimental Therapeutics 308 2004 993 1001
19. H. Medyouf, H. Alcalde, C. Berthier, M.C. Guillemin, N.R. dos Santos, A. Janin, D. Decaudin, H. de The, and J. Ghysdael Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia Nature Medicine 13 2007 736 741
20. B.A. Premack, and P. Gardner Signal transduction by T-cell receptors: mobilization of Ca and regulation of Ca-dependent effector molecules American Journal of Physiology 263 1992 C1119 C1140
21. A. Rao, C. Luo, and P.G. Hogan Transcription factors of the NFAT family: regulation and function Annual Review of Immunology 15 1997 707 747
22. N.J. Reynolds, and W.I. Al-Daraji Calcineurin inhibitors and sirolimus: mechanisms of action and applications in dermatology Clinical and Experimental Dermatology 27 2002 555 561
23. F. Rusnak, and P. Mertz Calcineurin: form and function Physiological Reviews 80 2000 1483 1521
24. J. Schumacher, I.F. de Larrinoa, and B. Tudzynski Calcineurin-responsive zinc finger transcription factor CRZ1 of Botrytis cinerea is required for growth, development, and full virulence on bean plants Eukaryotic Cell 7 2008 584 601
25. E. Serfling, F. Berberich-Siebelt, S. Chuvpilo, E. Jankevics, S. Klein-Hessling, T. Twardzik, and A. Avots The role of NF-AT transcription factors in T cell activation and differentiation Biochimica et Biophysica Acta 1498 2000 1 18
26. K.M. Shin, I.T. Kim, Y.M. Park, J. Ha, J.W. Choi, H.J. Park, Y.S. Lee, and K.T. Lee Anti-inflammatory effect of caffeic acid methyl ester and its mode of action through the inhibition of prostaglandin E2, nitric oxide and tumor necrosis factor-alpha production Biochemical Pharmacology 68 2004 2327 2336
27. 2+ signals and immunosuppression Nature 383 1996 837 840
28. W. Turner A new herball 1995 Cambridge university press
29. G. Wells, D. Haguenauer, B. Shea, M.E. Suarez-Almazor, V.A. Welch, and P. Tugwell Cyclosporine for rheumatoid arthritis Cochrane Database of Systematic Reviews 2000 CD001083
30. M. Wittmann, C. Killig, M. Bruder, R. Gutzmer, and T. Werfel Critical involvement of IL-12 in IFN-gamma induction by calcineurin antagonists in activated human lymphocytes Journal of Leukocyte Biology 80 2006 75 86
31. 13C NMR data for 10 phenylethanoid glycosides Magnetic Resonance in Chemistry 42 2004 659 662