Two-photon microscopy of cortical NADH fluorescence intensity changes: Correcting contamination from the hemodynamic response

Journal of Biomedical Optics

Volumn 16, Issue 10, 2011, Pages

  Baraghis, Edward ^a,b   Devor, Anna ^a,c   Fang, Qianqian ^a   Srinivasan, Vivek J ^a   Wu, Weicheng ^a   Lesage, Frédéric ^b   Ayata, Cenk ^a   Kasischke, Karl A ^d   Boas, David A ^a   Sakadžić, Sava ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b ÉCOLE POLYTECHNIQUE DE MONTRÉAL   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

brain imaging; correction algorithms; hemoglobin absorption; Monte Carlo simulations; nicotinamide adenine dinucleotide fluorescence; optical scattering; two photon laser scanning microscopy

Indexed keywords

BRAIN IMAGING; CORRECTION ALGORITHMS; MONTE CARLO SIMULATION; NICOTINAMIDE ADENINE DINUCLEOTIDE FLUORESCENCE; OPTICAL SCATTERING; TWO-PHOTON LASER SCANNING MICROSCOPIES;

ABSORPTION; ALGORITHMS; AMIDES; BLOOD; BRAIN; COMPUTER SIMULATION; FLUORESCENCE; HEMODYNAMICS; HEMOGLOBIN; HEMOGLOBIN OXYGEN SATURATION; HYDRODYNAMICS; LASER APPLICATIONS; LIGHT SCATTERING; METABOLISM; MONTE CARLO METHODS; MULTIPHOTON PROCESSES; OPTICAL PROPERTIES; PHOTONS; TISSUE;

FLUOROPHORES;

RATTUS;

FLUORESCENT DYE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXYHEMOGLOBIN;

ALGORITHM; ANIMAL; ARTICLE; BIOLOGICAL MODEL; BLOOD VOLUME; BRAIN CIRCULATION; BRAIN HYPOXIA; HEMODYNAMICS; HISTOLOGY; HYPEROXIA; LIGHT RELATED PHENOMENA; MALE; METABOLISM; METHODOLOGY; MICROVASCULATURE; MONTE CARLO METHOD; MULTIPHOTON MICROSCOPY; RAT; SOMATOSENSORY CORTEX; SPRAGUE DAWLEY RAT; STATISTICS; VASCULARIZATION;

ALGORITHMS; ANIMALS; BLOOD VOLUME; CEREBROVASCULAR CIRCULATION; FLUORESCENT DYES; HEMODYNAMICS; HYPEROXIA; HYPOXIA, BRAIN; MALE; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; MICROVESSELS; MODELS, NEUROLOGICAL; MONTE CARLO METHOD; NAD; OPTICAL PHENOMENA; OXYHEMOGLOBINS; RATS; RATS, SPRAGUE-DAWLEY; SOMATOSENSORY CORTEX;

EID: 80054867163     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.3633339     Document Type: Article

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