Mucins Differently Expressed in Various Ampullary Adenocarcinomas

Diagnostic Pathology

Volumn 6, Issue 1, 2011, Pages

  Wang, Tao ^a   Liang, Ye M ^a   Hu, Peng ^a   Cheng, Yu F ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Ampulla of vater; Common bile duct; Mucin; Neoplasm staging

Indexed keywords

MUCIN; TUMOR MARKER;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; BILE DUCT TUMOR; BIOSYNTHESIS; CANCER STAGING; FEMALE; HUMAN; KAPLAN MEIER METHOD; MALE; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; RETROSPECTIVE STUDY; VATER PAPILLA;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; AMPULLA OF VATER; COMMON BILE DUCT NEOPLASMS; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MUCINS; NEOPLASM STAGING; RETROSPECTIVE STUDIES; TUMOR MARKERS, BIOLOGICAL;

EID: 80054855484     PISSN: None     EISSN: 17461596     Source Type: Journal    
DOI: 10.1186/1746-1596-6-102     Document Type: Article

References (27)

1. Van Heek N, Maitra A, Koopmann J, Fedarko N, Jain A, Rahman A, Iacabuzio-Donahue C, Adsay V, Ashfaq R, Yeo C, et al. Gene expression profiling identifies markers of ampullary adenocarcinoma. Cancer Biology and Therapy 2004, 3:651-656. 10.4161/cbt.3.7.919, 15136764.
2. Heinrich S, Clavien P-A. Ampullary cancer. Current Opinion in Gastroenterology 2010, 26:280-285. 10.1097/MOG.0b013e3283378eb0, 20168227.
3. Sessa F, Furlan D, Zampatti C, Carnevali I, Franzi F, Capella C. Prognostic factors for ampullary adenocarcinomas: tumor stage, tumor histology, tumor location, immunohistochemistry and microsatellite instability. Virchows Arch 2007, 451:649-657. 10.1007/s00428-007-0444-1, 17653761.
4. Matsubayashi H, Watanabe H, Yamaguchi T, Ajioka Y, Nishikura K, Kijima H, Saito T. Differences in mucus and K ras mutation in relation to phenotypes of tumors of the papilla of Vater. Cancer 1999, 86:596-607. 10.1002/(SICI)1097-0142(19990815)86:4<596::AID-CNCR8>3.0.CO;2-H, 10440687.
5. Chu PG, Schwarz RE, Lau SK, Yen Y, Weiss LM. Immunohistochemical Staining in the Diagnosis of Pancreatobiliary and Ampulla of Vater Adenocarcinoma: Application of CDX2, CK17, MUC1, and MUC2. Am J Surg Pathol 2005, 29:359-367. 10.1097/01.pas.0000149708.12335.6a, 15725805.
6. Fischer H-P, Zhou H. Pathogenesis of carcinoma of the papilla of Vater. J Hepatobiliary Pancreat Surg 2004, 11:301-309. 10.1007/s00534-004-0898-3, 15549428.
7. Gürbüz Y, Klöppel G. Differentiation pathways in duodenal and ampullary carcinomas: a comparative study on mucin and trefoil peptide expression, including gastric and colon carcinomas. Virchows Arch 2004, 444:536-541.
8. Hollingsworth MA, Swanson BJ. Mucins in cancer: protection and control of the cell surface. Nature Reviews Cancer 2004, 4:45-60. 10.1038/nrc1251, 14681689.
9. Lee MJ, Lee HS, Kim WH, Choi Y, Yang M. Expression of mucins and cytokeratins in primary carcinomas of the digestive system. Mod Pathol 2003, 16:403-410. 10.1097/01.MP.0000067683.84284.66, 12748245.
10. Hinoda Y, Ikematsu Y, Horinochi M, Sato S, Yamamoto K, Nakano T, Fukui M, Suehiro Y, Hamanaka Y, Nishikawa Y. Increased expression of MUC1 in advanced pancreatic cancer. J Gastroenterol 2003, 38:1162-1166. 10.1007/s00535-003-1224-6, 14714254.
11. Aloysius M, Zaitoun A, Awad S, Ilyas M, Rowlands B, Lobo D. Mucins and CD56 as markers of tumour invasion and prognosis in periampullary cancer. Br J Surg 2010, 97:1269-1278. 10.1002/bjs.7107, 20602499.
12. Capella C, Albarello L, Capelli P, Sessa F, Zamboni G. Carcinoma of the exocrine pancreas: The histology report. Digestive and Liver Disease 2011, 43:S282-S292.
13. Yonezawa S, Higashi M, Yamada N, Yokoyama S, Goto M. Significance of mucin expression in pancreatobiliary neoplasms. Journal of Hepato-Biliary-Pancreatic Sciences 2010, 17:108-124. 10.1007/s00534-009-0174-7, 19787286.
14. de Paiva Haddad L, Patzina R, Penteado S, Montagnini A, da Cunha J, Machado M, Jukemura J. Lymph Node Involvement and Not the Histophatologic Subtype Is Correlated with Outcome After Resection of Adenocarcinoma of the Ampulla of Vater. J Gastrointest Surg 2010, 14:719-728. 10.1007/s11605-010-1156-4, 20107918.
15. Higashi M, Goto M, Saitou M, Shimizu T, Rousseau K, Batra S, Yonezawa S. Immunohistochemical study of mucin expression in periampullary adenomyoma. Journal of Hepato-Biliary-Pancreatic Sciences 2010, 17:275-283. 10.1007/s00534-009-0176-5, 19784541.
16. Hamanaka Y, Suehiro Y, Fukui M, Shikichi K, Imai K, Hinoda Y. Circulating anti MUC1 IgG antibodies as a favorable prognostic factor for pancreatic cancer. Int J Cancer 2003, 103:97-100. 10.1002/ijc.10801, 12455059.
17. Westgaard A, Schjølberg AR, Cvancarova M, Eide TJ, Clausen OPF, Gladhaug IP. Differentiation markers in pancreatic head adenocarcinomas: MUC1 and MUC4 expression indicates poor prognosis in pancreatobiliary differentiated tumours. Histopathology 2009, 54:337-347. 10.1111/j.1365-2559.2009.03227.x, 2680278, 19236510.
18. Kawabata Y, Tanaka T, Nishisaka T, Inao T, Nishi T, Yano S. Cytokeratin 20 (CK20) and apomucin 1 (MUC1) expression in ampullary carcinoma: Correlation with tumor progression and prognosis. Diagnostic Pathology 2010, 5:75. 3003636, 21106111.
19. Jinfeng M, Kimura W, Hirai I, Sakurai F, Moriya T, Mizutani M. Expression of MUC5AC and MUC6 in invasive ductal carcinoma of the pancreas and relationship with prognosis. International journal of gastrointestinal cancer 2003, 34:9-18.
20. Lüttges J, Feyerabend B, Buchelt T, Pacena M, Klöppel G. The mucin profile of noninvasive and invasive mucinous cystic neoplasms of the pancreas. The American journal of surgical pathology 2002, 26:466. 10.1097/00000478-200204000-00008, 11914624.
21. Yuan Z, Wong S, Borrelli A, Chung MA. Down-regulation of MUC1 in cancer cells inhibits cell migration by promoting E-cadherin/catenin complex formation. Biochem Biophys Res Commun 2007, 362:740-746. 10.1016/j.bbrc.2007.08.074, 17764657.
22. Singh PK, Wen Y, Swanson BJ, Shanmugam K, Kazlauskas A, Cerny RL, Gendler SJ, Hollingsworth MA. Platelet-Derived Growth Factor Receptor β-Mediated Phosphorylation of MUC1 Enhances Invasiveness in Pancreatic Adenocarcinoma Cells. Cancer Res 2007, 67:5201-5210. 10.1158/0008-5472.CAN-06-4647, 17545600.
23. Kalra A, Campbell R. Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: overcoming cellular barriers for therapeutic gain. Br J Cancer 2007, 97:910-918. 10.1038/sj.bjc.6603972, 2360416, 17912239.
24. Chang HJ, Kim SW, Lee BL, Hong EK, Kim WH. Phenotypic alterations of mucins and cytokeratins during gallbladder carcinogenesis. Pathol Int 2004, 54:576-584. 10.1111/j.1440-1827.2004.01666.x, 15260848.
25. Xiuru Z, Fang L, Fang H. Expression and significance of Muc-1, Muc-2, Muc5AC, Muc-6 in hyperplastic polyp, globoid dysplasia, gastric signet ring cell carcinoma.
26. Yu X, Rong W, Xu F, Xu G, Sun Y, Feng M. Expression and clinical significance of Mucin and E-cadherin in colorectal tumors]. Ai zheng= Aizheng= Chinese journal of cancer 2007, 26:1204.
27. Yonezawa S, Horinouchi M, Osako M, Kubo M, Takao S, Arimura Y, Nagata K, Tanaka S, Sakoda K, Aikou T. Gene expression of gastric type mucin (MUC5AC) in pancreatic tumors: its relationship with the biological behavior of the tumor. Pathol Int 1999, 49:45-54. 10.1046/j.1440-1827.1999.00823.x, 10227724.