Strong association between polycythemia and glucose intolerance in older adults living at high altitudes in the andes

Journal of the American Geriatrics Society

Volumn 59, Issue 10, 2011, Pages 1971-1973

  Okumiya, Kiyohito ^a   Fukutomi, Eriko ^a   Kimura, Yumi ^a   Ishimoto, Yasuko ^a   Chen, Wen Ling ^a   Ishikawa, Motonao ^b   Hozo, Reiko ^b   Sakamoto, Ryota ^a   Wada, Taizo ^c   Otsuka, Kuniaki ^b   Inamura, Tetsuya ^d   Lazo, Marcela ^e   Lu, Jose Perez ^e   Garcia, Patricia J ^e   Matsubayashi, Kozo ^b  

^a KYOTO UNIVERSITY SCHOOL OF PUBLIC HEALTH   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d AICHI PREFECTURAL UNIVERSITY   (Japan)

^e UNIVERSIDAD PERUANA CAYETANO HEREDIA   (Peru)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN;

AGING; ALTITUDE; ALTITUDE DISEASE; BODY MASS; DIABETES MELLITUS; DISEASE ASSOCIATION; GLUCOSE INTOLERANCE; HUMAN; HYPOXIA; LETTER; LONGITUDINAL STUDY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; OBESITY; OXIDATIVE STRESS; OXYGEN SATURATION; OXYGEN SUPPLY; PERU; POLYCYTHEMIA; PREVALENCE; VASODILATATION;

ACCLIMATIZATION; AGE FACTORS; AGED; AGED, 80 AND OVER; ALTITUDE SICKNESS; COMORBIDITY; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS; FEMALE; GLUCOSE INTOLERANCE; HEALTH SURVEYS; HUMANS; MALE; MIDDLE AGED; PERU; POLYCYTHEMIA; SEX FACTORS;

EID: 80054825679     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/j.1532-5415.2011.03610_8.x     Document Type: Letter

References (8)

1. Okumiya K, Sakamoto R, Kimura Y, et al. Strong association between polycythemia and glucose intolerance in elderly high-altitude dwellers in Asia. J Am Geriatr Soc 2010; 58: 609-611.
2. Okumiya K, Sakamoto R, Kimura Y, et al. Diabetes and hypertension in elderly highlanders in Asia. J Am Geriatr Soc 2010; 58: 1193-1195.
3. Beall CM,. Andean, Tibetan, and Ethiopian patterns of adaptation to high-altitude hypoxia. Integrative Comparative Biol 2006; 46: 18-24.
4. Leon-Velarde F, Arregui A, Monge CC, et al. Ageing at high altitude and the risk of chronic mountain sickness. J Wilderness Med 1993; 4: 183-188.
5. Oltmanns KM, Gehring H, Rudolf S, et al. Hypoxia causes glucose intolerance in Humans. Am J Respir Crit Care Med 2004; 169: 1231-1237.
6. Askew EW,. Work at high altitude and oxidative stress: Antioxidant nutrients. Toxicology 2002; 180: 107-119.
7. Ogihara T, Asano T, Katagiri H, et al. Oxidative stress induces insulin resistance by activating the nyclear factor-κB pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase. Diabetologia 2004; 46: 794-805.
8. World Health Organization. Definition and Diagnosis of Diabetes Mellitus and Intermediate Hyperglycemia. Report of a WHO/IDF consultation. 2006; 9-27.