Is frailty associated with cardiovascular drug use?

Journal of the American Geriatrics Society

Volumn 59, Issue 10, 2011, Pages 1977-1979

  Pozos Lõpez, Teresa ^a   Navarrete Reyes, Ana Patricia ^b   Úvila Funes, José Alberto ^c  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^b INSERM   (France)

^c UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN RECEPTOR ANTAGONIST; CALCIUM CHANNEL BLOCKING AGENT; CARDIOVASCULAR AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; FIBRIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NITRATE;

AGED; AGING; CARDIOVASCULAR DISEASE; COMORBIDITY; DRUG EFFECT; DRUG USE; DYSLIPIDEMIA; FEMALE; FRAIL ELDERLY; FUNCTIONAL ASSESSMENT; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; LETTER; MAJOR CLINICAL STUDY; MALE; MUSCLE ATROPHY; MUSCLE MASS; MUSCLE STRENGTH; PHYSICAL PERFORMANCE; SEX DIFFERENCE; WALKING SPEED;

AGED; AGED, 80 AND OVER; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CARDIOVASCULAR AGENTS; COHORT STUDIES; FEMALE; FRAIL ELDERLY; HEALTH SURVEYS; HUMANS; MALE; MEXICO; RISK FACTORS; SARCOPENIA;

EID: 80054813272     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/j.1532-5415.2011.03610_12.x     Document Type: Letter

References (10)

1. Onder G, Penninx BW, Balkrishnan R, et al. Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: An observational study. Lancet 2002; 359: 926-930.
2. Sumukadas D, Witham MD, Struthers AD, et al. Effect of perindopril on physical function in elderly people with functional impairment: A randomized controlled trial. CMAJ 2007; 177: 867-874.
3. Di Bari M, van de Poll-Franse LV, Onder G, et al. Antihypertensive medications and differences in muscle mass in older persons: The Health, Aging and Body Composition Study. J Am Geriatr Soc 2004; 52: 961-966.
4. Úvila-Funes JA, Piña-Escudero S, Aguilar-Navarro S, et al. Cognitive impairment and low physical activity are the components of frailty more strongly associated with disability. J Nutr Health Aging 2011; 15: in press.
5. Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: Evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001; 56A: M146-M156.
6. Gray SL, LaCroix AZ, Aragaki AK, et al. Angiotensin-converting enzyme inhibitor use and incident frailty in women aged 65 and older: Prospective findings from the Women's Health Initiative Observational Study. J Am Geriatr Soc 2009; 57: 297-303.
7. LaCroix AZ, Gray SL, Aragaki A, et al. Statin use and incident frailty in women aged 65 years or older: Prospective findings from the Women's Health Initiative Observational Study. J Gerontol A Biol Sci Med Sci 2008; 63A: 369-675.
8. Ashfield TA, Syddall HE, Martin HJ, et al. Grip strength and cardiovascular drug use in older people: Findings from the Hertfordshire Cohort Study. Age Ageing 2010; 39: 185-191.
9. Aplin M, Christensen GL, Hansen JL, et al. Pharmacologic perspectives of functional selectivity by the angiotensin II type 1 receptor. Trends Cardiovasc Med 2008; 18: 305-312.
10. Xue B, Singh M, Guo F, et al. Protective actions of estrogen on angiotensin II-induced hypertension: Role of central nitric oxide. Am J Physiol Heart Circ Physiol 2009; 297: H1638-H1646.