Transcriptome profiling and sequencing of differentiated human hematopoietic stem cells reveal lineage-specific expression and alternative splicing of genes

Physiological Genomics

Volumn 43, Issue 20, 2011, Pages 1117-1134

  Liu, Poching ^a   Barb, Jennifer ^b   Woodhouse, Kimberly ^a   Taylor VI, James G ^a   Munson, Peter J ^b   Raghavachari, Nalini ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Differentiation; Gene expression; Hematopoiesis; Microarrays; qPCR; RNAseq; Splicing

Indexed keywords

ALANINE; ASPARTIC ACID; BETA CATENIN; CYTOKINE; RAC PROTEIN; RHO KINASE; TRANSCRIPTOME; WNT PROTEIN;

ALTERNATIVE RNA SPLICING; AMINO ACID METABOLISM; ARTICLE; CD34 SELECTION; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; CELL SPECIFICITY; CELL THERAPY; COMPARATIVE STUDY; CONTROLLED STUDY; ERYTHROID CELL; ERYTHROPOIESIS; EXOME; EXON; GENE EXPRESSION PROFILING; GENE SEQUENCE; GENETIC CORRELATION; GENOME ANALYSIS; GRANULOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MEGAKARYOPOIESIS; MICROARRAY ANALYSIS; PRIORITY JOURNAL; RNA SEQUENCE; SIGNAL TRANSDUCTION;

ALTERNATIVE SPLICING; ANTIGENS, CD34; CELL DIFFERENTIATION; CELL LINEAGE; CLUSTER ANALYSIS; ERYTHROID CELLS; EXONS; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; PRINCIPAL COMPONENT ANALYSIS; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION; TRANSCRIPTOME;

EID: 80054810315     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00099.2011     Document Type: Article

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