Two-photon fluorescence vascular bioimaging with new bioconjugate probes selective toward the vascular endothelial growth factor receptor 2

Bioconjugate Chemistry

Volumn 22, Issue 10, 2011, Pages 2060-2071

  Andrade, Carolina D ^a   Yanez, Ciceron O ^a   Ahn, Hyo Yang ^a   Urakami, Takeo ^a   Bondar, Mykhailo V ^b   Komatsu, Masanobu ^a   Belfield, Kevin D ^c  

^a UNIVERSITY OF CENTRAL FLORIDA   (United States)

^b BURNHAM INSTITUTE   (United States)

^c INSTITUTE OF PHYSICS   (Ukraine)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; ENDOTHELIAL CELLS; FLUORESCENCE; FLUORESCENCE MICROSCOPY; PHOTONS; PROBES; TWO PHOTON PROCESSES;

BIO-CONJUGATION; BIO-IMAGING; BIOCONJUGATES; FLUORESCENCE QUANTUM YIELD; FLUORESCENT DYES; IN-VITRO; PROPERTY; SYNTHESIS AND CHARACTERIZATIONS; TWO PHOTON FLUORESCENCE; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR;

TUMORS;

FLUORESCENT DYE; MONOCLONAL ANTIBODY DC101; VASCULOTROPIN RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL STRUCTURE; CONJUGATION; FLUORESCENCE MICROSCOPY; IMAGING SYSTEM; IN VITRO STUDY; LIGHT ABSORPTION; MALE; MOUSE; NONHUMAN; QUANTUM YIELD; SYNTHESIS;

EID: 80054797649     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc200299z     Document Type: Article

References (29)

1. Callagy, G., Dimitriadis, E., Harmey, J., Bouchier-Hayes, D., Leader, M., and Kay, E. (2000) Immunohistochemical measurement of tumor vascular endothelial growth factor in breast cancer - A more reliable predictor of tumor stage than microvessel density or serum vascular endothelial growth factor Appl. Immunohistochem. Mol. Morphol. 8, 104-109 (Pubitemid 30609970)
2. Tozer, G. M., Ameer-Beg, S. M., Baker, J., Barber, P. R., Hill, S. A., Hodgkiss, R. J., Locke, R., Prise, V. E., Wilson, I., and Vojnovic, B. (2005) Intravital imaging of tumour vascular networks using multi-photon fluorescence microscopy Adv. Drug Delivery Rev. 57, 135-152 (Pubitemid 39424069)
3. Gao, J. H., Chen, K., Xie, R. G., Xie, J., Yan, Y. J., Cheng, Z., Peng, X. G., and Chen, X. Y. (2010) In Vivo Tumor-Targeted Fluorescence Imaging Using Near-Infrared Non-Cadmium Quantum Dots Bioconjugate Chem. 21, 604-609
4. Wang, L. V. (2009) Multiscale photoacoustic microscopy and computed tomography Nat. Photonics 3, 503-509
5. Zhang, H. F., Maslov, K., Li, M. L., Stoica, G., and Wang, L. H. V. (2006) In vivo volumetric imaging of subcutaneous microvasculature by photoacoustic microscopy Opt. Express 14, 9317-9323 (Pubitemid 44507197)
6. Carmeliet, P. (2005) Angiogenesis in life, disease and medicine Nature 438, 932-936 (Pubitemid 43093958)
7. Asano, M., Yukita, A., Matsumoto, T., Kondo, S., and Suzuki, H. (1995) Inhibition of tumor-growth and metastasis by immunoneutralizing monoclonal-antibody to vascular endothelial growth-factor vascular-permeability factor (121) Cancer Res. 55, 5296-5301
8. Ellis, L. M., Curley, S. A., and Grothey, A. (2005) Surgical Resection After Downsizing of Colorectal Liver Metastasis in the Era of Bevacizumab J. Clin. Oncol. 23, 4853-4855 (Pubitemid 46223989)
9. Ferrara, N. and Kerbel, R. S. (2005) Angiogenesis as a therapeutic target Nature 438, 967-974 (Pubitemid 43093963)
10. Kowanetz, M. and Ferrara, N. (2006) Vascular Endothelial Growth Factor Signaling Pathways: Therapeutic Perspective Clin. Cancer Res. 12, 5018-5022 (Pubitemid 44453326)
11. Backer, M. V., Gaynutdinov, T. I., Patel, V., Bandyopadhyaya, A. K., Thirumamagal, B. T. S., Tjarks, W., Barth, R. F., Claffey, K., and Backer, J. M. (2005) Vascular endothelial growth factor selectively targets boronated dendrimers to tumor vasculature Mol. Cancer Ther. 4, 1423-1429
12. Saban, M. R., Backer, J. M., Backer, M. V., Maier, J., Fowler, B., Davis, C. A., Simpson, C., Wu, X.-R., Birder, L., Freeman, M. R., Soker, S., Hurst, R. E., and Saban, R. (2008) VEGF receptors and neuropilins are expressed in the urothelial and neuronal cells in normal mouse urinary bladder and are upregulated in inflammation Am. J. Physiol. Renal Physiol. 295, F60-72
13. Göppert-Mayer, M. (1931) Über Elementarakte mit zwei Quantensprüngen Ann. Phys. 401, 273-294
14. Schafer-Hales, K. J., Belfield, K. D., Yao, S., Frederiksen, P. K., Hales, J. M., and Kolattukudy, P. E. (2005) Fluorene-based fluorescent probes with high two-photon action cross-sections for biological multiphoton imaging applications J. Biomed. Opt. 10, 1-8
15. Morales, A. R., Schafer-Hales, K. J., Marcus, A. I., and Belfield, K. D. (2008) Amine-Reactive Fluorene Probes: Synthesis, Optical Characterization, Bioconjugation, and Two-Photon Fluorescence Imaging Bioconjugate Chem. 19, 2559-2567
16. Andrade, C. D., Yanez, C. O., Rodriguez, L., and Belfield, K. D. (2010) A Series of Fluorene-Based Two-Photon Absorbing Molecules: Synthesis, Linear and Nonlinear Characterization, and Bioimaging J. Org. Chem. 75, 3975-3982
17. Makarov, N. S., Drobizhev, M., and Rebane, A. (2008) Two-photon absorption standards in the 550-1600 nm excitation wavelength range Opt. Express 16, 4029-4047 (Pubitemid 351434377)
18. Belfield, K. D., Schafer, K. J., Mourad, W., and Reinhardt, B. A. (2000) Synthesis of new two-photon absorbing fluorene derivatives via Cu-mediated Ullmann condensations J. Org. Chem. 65, 4475-4481 (Pubitemid 30620552)
19. Morales, A. R., Yanez, C. O., Schafer-Hales, K. J., Marcus, A. I., and Belfield, K. D. (2009) Biomolecule Labeling and Imaging with a New Fluorenyl Two-Photon Fluorescent Probe Bioconjugate Chem. 20, 1992-2000
20. Denk, W. and Svoboda, K. (1997) Photon upmanship: Why multiphoton imaging is more than a gimmick Neuron 18, 351-357 (Pubitemid 27138784)
21. Oheim, M., Beaurepaire, E., Chaigneau, E., Mertz, J., and Charpak, S. (2001) Two-photon microscopy in brain tissue: parameters influencing the imaging depth J. Neurosci. Methods 111, 29-37 (Pubitemid 33733532)
22. Wang, X. H., Nguyen, D. M., Yanez, C. O., Rodriguez, L., Ahn, H. Y., Bonder, M. V., and Belfield, K. D. (2010) High-Fidelity Hydrophilic Probe for Two-Photon Fluorescence Lysosomal Imaging J. Am. Chem. Soc. 132, 12237-12239
23. Oheim, M., Beaurepaire, E., Chaigneau, E., Mertz, J., and Charpak, S. (2001) Two-photon microscopy in brain tissue: parameters influencing the imaging depth J. Neurosci. Methods 112, 205-205
24. McMullen, J. D., Kwan, A. C., Williams, R. M., and Zipfel, W. R. (2010) Enhancing collection efficiency in large field of view multiphoton microscopy J. Microsc. 241, 119-124
25. Beaurepaire, E., Oheim, M., and Mertz, J. (2001) Ultra-deep two-photon fluorescence excitation in turbid media Opt. Commun. 188, 25-29 (Pubitemid 32196122)
26. Jain, R. K., Munn, L. L., and Fukumura, D. (2002) Dissecting tumour pathophysiology using intravital microscopy Nat. Rev. Cancer 2, 266-276 (Pubitemid 37328780)
27. Fukumura, D. and Jain, R. K. (2007) Tumor microvasculature and microenvironment: Targets for anti-angiogenesis and normalization Microvasc. Res. 74, 72-84 (Pubitemid 350051025)
28. Garkavtsev, I., Kozin, S. V., Chernova, O., Xu, L., Winkler, F., Brown, E., Barnett, G. H., and Jain, R. K. (2004) The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis Nature 428, 328-332 (Pubitemid 38418804)
29. Tong, R. T., Boucher, Y., Kozin, S. V., Winkler, F., Hicklin, D. J., and Jain, R. K. (2004) Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors Cancer Res. 64, 3731-3736 (Pubitemid 38697278)