Absence of TCR loci chromosomal translocations in cutaneous T-cell lymphomas

Cancer Genetics

Volumn 204, Issue 7, 2011, Pages 405-409

  Salgado, Rocío ^a,b   Gallardo, Fernando ^a   Servitje, Octavio ^c   Estrach, Teresa ^d   García Muret, María Pilar ^e   Romagosa, Vicente ^c   Florensa, Lourdes ^a   Serrano, Sergi ^a   Salido, Marta ^a   Solé, Francesc ^a   Pujol, Ramon M ^a   Espinet, Blanca ^a  

^a HOSPITAL DEL MAR   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^d HOSPITAL CLÍNIC   (Spain)

^e HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

Author keywords

Cutaneous T cell lymphomas; Fluorescence in situ hybridization; TCR

Indexed keywords

CD30 ANTIGEN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN; LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; AGED; ARTICLE; CARCINOGENESIS; CHROMOSOME 14Q; CHROMOSOME 7P; CHROMOSOME 7Q; CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION; CLINICAL ARTICLE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; CUTANEOUS T CELL LYMPHOMA; CYTOGENETICS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCUS; HUMAN; HUMAN CELL; HUMAN TISSUE; LARGE CELL LYMPHOMA; MALE; MYCOSIS FUNGOIDES; ONCOGENE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEZARY SYNDROME; TCR GENE; TCRAD GENE; TCRB GENE; TCRG GENE; TETRASOMY; TRISOMY; CHROMOSOME 7; GENE TRANSLOCATION; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; SKIN TUMOR; T LYMPHOCYTE RECEPTOR GENE;

ADULT; AGED; AGED, 80 AND OVER; CHROMOSOMES, HUMAN, PAIR 7; FEMALE; GENES, T-CELL RECEPTOR; GENETIC LOCI; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MIDDLE AGED; MYCOSIS FUNGOIDES; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RETROSPECTIVE STUDIES; SEZARY SYNDROME; SKIN NEOPLASMS; TETRASOMY; TRANSLOCATION, GENETIC;

EID: 80054790597     PISSN: 22107762     EISSN: 22107770     Source Type: Journal    
DOI: 10.1016/j.cancergen.2011.05.004     Document Type: Article

References (8)

1. Gesk S., Martín-Subero J.I., Harder L., et al. Molecular cytogenetic detection of chromosomal breakpoints in T-cell receptor gene loci. Leukemia 2003, 17:738-745.
2. Feldman A.L., Law M., Grogg K.L., et al. Incidence of TCR and TCL1 gene translocations and isochromosome 7q in peripheral T-cell lymphomas using fluorescence in situ hybridization. Am J Clin Pathol 2008, 130:178-185.
3. Batista D.A., Vonderheid E.C., Hawkins A., et al. Multicolor fluorescence in situ hybridization (SKY) in mycosis fungoides and Sézary syndrome: search for recurrent chromosome abnormalities. Genes Chromosomes Cancer 2006, 45:383-391.
4. Espinet B., Salido M., Pujol R.M., et al. Genetic characterization of Sézary's syndrome by conventional cytogenetics and cross-species color banding fluorescent in situhybridization. Haematologica 2004, 89:165-167.
5. van Doorn R., van Kester M.S., Dijkman R., et al. Oncogenomic analysis of mycosis fungoides reveals major differences with Sezary syndrome. Blood 2009, 113:127-136.
6. Salgado R., Servitje O., Gallardo F., et al. Oligonucleotide array-CGH identifies genomic subgroups and prognostic markers for tumor stage mycosis fungoides. J Invest Dermatol 2010, 130:1126-1135.
7. van Kester M.S., Tensen C.P., Vermeer M.H., et al. Cutaneous anaplastic large cell lymphoma and peripheral T-cell lymphoma NOS show distinct chromosomal alterations and differential expression of chemokine receptors and apoptosis regulators. J Invest Dermatol 2010, 130:563-575.
8. + anaplastic large-cell lymphomas show a heterogeneous genomic profile: an oligonucleotide arrayCGH approach. J Invest Dermatol 2011, 131:269-271.