Downregulation of Glutamine Synthetase via GLAST Suppression Induces Retinal Axonal Swelling in a Rat Ex Vivo Hydrostatic Pressure Model

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 9, 2011, Pages 6604-6616

  Ishikawa, Makoto ^a   Yoshitomi, Takeshi ^a   Zorumski, Charles F ^b   Izumi, Yukitoshi ^b  

^a AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(2S,3S)3 [3 [4 (TRIFLUOROMETHYL)BENZOYLAMINO]BENZYLOXY]ASPARTATE; EXCITATORY AMINO ACID TRANSPORTER; GLUTAMATE AMMONIA LIGASE; METHIONINE SULFOXIMINE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; VIMENTIN; (2S,3S) 3 (3 (4 (TRIFLUOROMETHYL)BENZOYLAMINO)BENZYLOXY)ASPARTATE; (2S,3S)-3-(3-(4-(TRIFLUOROMETHYL)BENZOYLAMINO)BENZYLOXY)ASPARTATE; ASPARTIC ACID; DRUG DERIVATIVE; EXCITATORY AMINO ACID TRANSPORTER 1; GLUTAMIC ACID; MESSENGER RNA; SLC1A3 PROTEIN, RAT;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EYE SWELLING; HYDROSTATIC PRESSURE; IMMUNOCHEMISTRY; IMMUNOCYTOCHEMISTRY; LASER MICROSCOPY; MALE; NERVE CELL LESION; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA; RETINA GANGLION CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; RETINA DEGENERATION; SPRAGUE DAWLEY RAT;

ANIMALS; ASPARTIC ACID; AXONS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; DOWN-REGULATION; EXCITATORY AMINO ACID TRANSPORTER 1; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GLUTAMATE-AMMONIA LIGASE; GLUTAMIC ACID; HYDROSTATIC PRESSURE; MALE; METHIONINE SULFOXIMINE; RATS; RATS, SPRAGUE-DAWLEY; RETINAL DEGENERATION; RETINAL GANGLION CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 80054789224     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-7375     Document Type: Article

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