Evidence of reassortment of pandemic H1N1 influenza virus in swine in Argentina: Are we facing the expansion of potential epicenters of influenza emergence?

Influenza and other Respiratory Viruses

Volumn 5, Issue 6, 2011, Pages 409-412

  Pereda, Ariel ^a   Rimondi, Agustina ^a   Cappuccio, Javier ^b   Sanguinetti, Ramon ^c   Angel, Matthew ^d   Ye, Jianqiang ^d   Sutton, Troy ^d   Dibárbora, Marina ^a   Olivera, Valeria ^a   Craig, Maria I ^a   Quiroga, Maria ^b   Machuca, Mariana ^b   Ferrero, Andrea ^d   Perfumo, Carlos ^b   Perez, Daniel R ^d  

^a INSTITUTO NACIONAL DE TECNOLOGÍA AGROPECUARIA INTA   (Argentina)

^b UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

^c Servicio Nacional de Sanidad y Calidad Agroalimentaria Argentina   (Argentina)

^d UNIVERSITY OF MARYLAND   (United States)

Author keywords

H1N1 2009 pandemic virus; Pigs; Reassortment

Indexed keywords

VIRUS RNA;

ANIMAL TISSUE; ARGENTINA; ARTICLE; COUGHING; DYSPNEA; FEVER; HEALTH HAZARD; HISTOPATHOLOGY; HUMAN LIKE SWINE INFLUENZA VIRUS; INFLUENZA VIRUS; INFLUENZA VIRUS A H1N1; LETHARGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTH AMERICA; SWINE; SWINE INFLUENZA; SWINE INFLUENZA VIRUS; VIROLOGY; VIRUS ISOLATION;

ANIMALS; ARGENTINA; INFLUENZA A VIRUS, H1N1 SUBTYPE; ORTHOMYXOVIRIDAE INFECTIONS; PANDEMICS; REASSORTANT VIRUSES; SWINE; SWINE DISEASES;

EID: 80054781475     PISSN: 17502640     EISSN: 17502659     Source Type: Journal    
DOI: 10.1111/j.1750-2659.2011.00246.x     Document Type: Article

References (21)

1. World Health Organization. Pandemic (H1N1) 2009: update 89. Available at (Accessed 26 February 2010).
2. Dawood FS, Jain S, Finelli L et al. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 2009; 360:2605-2615.
3. Pereda A, Cappuccio J, Quiroga MA et al. Pandemic (H1N1) 2009 outbreak on pig farm, Argentina. Emerg Infect Dis 2010; 16:304-307.
4. Pasma T, Joseph T. Pandemic (H1N1) 2009 infection in swine herds, Manitoba, Canada. Emerg Infect Dis 2010; 16:706-708.
5. Smith GJ, Vijaykrishna D, Bahl J et al. Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic. Nature 2009; 459:1122-1125.
6. Vijaykrishna D, Poon LL, Zhu HC et al. Reassortment of pandemic H1N1/2009 influenza A virus in swine. Science 2010; 328:1529.
7. Yoon KJ, Janke BH. Swine influenza: etiology, epidemiology, and diagnosis; in Morilla A, Yoon KJ, Zimmerman JJ (eds): Trends in Emerging Viral Infections of Swine. Ames: Blackwell Publishing, 2002; 23-28.
8. Webby RJ, Swenson SL, Krauss SL et al. Evolution of swine H3N2 influenza viruses in the United States. J Virol 2000; 74:8243-8251.
9. Richt JA, Lager KM, Janke BH et al. Pathogenic and antigenic properties of phylogenetically distinct reassortant H3N2 swine influenza viruses cocirculating in the United States. J Clin Microbiol 2003; 41:3198-3205.
10. Webby RJ, Rossow K, Erickson G, Sims Y, Webster R. Multiple lineages of antigenically and genetically diverse influenza A virus co-circulate in the United States swine population. Virus Res 2004; 103:67-73.
11. Olsen CW, Karasin AI, Carman S et al. Triple reassortant H3N2 influenza A viruses, Canada, 2005. Emerg Infect Dis 2006; 12:1132-1135.
12. Ma W, Gramer M, Rossow K, Yoon KJ. Isolation and genetic characterization of new reassortant H3N1 swine influenza virus from pigs in the midwestern United States. J Virol 2006; 80:5092-5096.
13. Lekcharoensuk P, Lager KM, Vemulapalli R, Woodruff M, Vincent AL, Richt JA. Novel swine influenza virus subtype H3N1, United States. Emerg Infect Dis 2006; 12:787-794.
14. Karasin AI, Landgraf J, Swenson S et al. Genetic characterization of H1N2 influenza A viruses isolated from pigs throughout the United States. J Clin Microbiol 2002; 40:1073-1079.
15. Choi YK, Goyal SM, Farnham MW, Joo HS. Phylogenetic analysis of H1N2 isolates of influenza A virus from pigs in the United States. Virus Res 2002; 87:173-179.
16. Ma W, Vincent AL, Gramer MR et al. Identification of H2N3 influenza A viruses from swine in the United States. Proc Natl Acad Sci USA 2007; 104:20949-20954.
17. Vincent AL, Ma W, Lager KM et al. Characterization of a newly emerged genetic cluster of H1N1 and H1N2 swine influenza virus in the United States. Virus Genes 2009; 39:176-185.
18. Peiris JS, Poon LL, Guan Y. Emergence of a novel swine-origin influenza A virus (S-OIV) H1N1 virus in humans. J Clin Virol 2009; 45:169-173.
19. Cappuccio J, Pereda A, Insarralde L et al. An outbreak of influenza virus H3N2 subtype in a farm in Argentina; in D'Allaire S, Friendship R (eds): Proceedings of the 21st IPVS Congress. Vancouver, Canada: International Pig Veterinary Society, 2010; 563.
20. Ministerio de Salud. Alerta epidemiologico. Available at (Accessed 30 December 2009).
21. Centers for Disease Control and Prevention (CDC). 2009. Available at (Accessed 30 April 2009) (revision 1).