Suboptimal use of statins at treatment initiation

European Journal of Clinical Pharmacology

Volumn 67, Issue 9, 2011, Pages 971-973

  Kiviniemi, Vesa ^a   Peura, Piia ^a   Helin Salmivaara, Arja ^b,c   Martikainen, Jaana E ^d   Hartikainen, Juha ^e,f   Huupponen, Risto ^b,g   Korhonen, Maarit Jaana ^b  

^a Finnish Medicines Agency   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c HOSPITAL DISTRICT OF HELSINKI AND UUSIMAA   (Finland)

^d SOCIAL INSURANCE INSTITUTION   (Finland)

^e UNIVERSITY OF EASTERN FINLAND   (Finland)

^f KUOPIO UNIVERSITY HOSPITAL   (Finland)

^g TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN;

ADULT; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; COMORBIDITY; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DOSE RESPONSE; DRUG COST; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG POTENCY; DRUG SUBSTITUTION; DRUG UNDERDOSE; DRUG USE; DRUG WITHDRAWAL; DYSLIPIDEMIA; FEMALE; FINLAND; FOLLOW UP; HIGH RISK PATIENT; HUMAN; LETTER; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; PRESCRIPTION; PRIORITY JOURNAL; REIMBURSEMENT; RISK FACTOR; RISK REDUCTION;

CARDIOVASCULAR DISEASES; COMORBIDITY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG PRESCRIPTIONS; DRUG UTILIZATION REVIEW; FINLAND; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS;

EID: 80054780475     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-011-1037-0     Document Type: Letter

References (16)

1. Brugts JJ, Yetgin T, Hoeks SE et al (2009) The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: Meta-analysis of randomised controlled trials. Br Med J 338:b2376
2. Heart Protection Study Collaborative Group (2002) MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: A randomised placebo-controlled trial. Lancet 360:7-22
3. Cholesterol Treatment Trialists' Collaboration (2010) Efficacy and safety of more intensive lowering of LDL cholesterol: A metaanalysis of data from 170 000 participants in 26 randomised trials. Lancet 376:1670-1681
4. Walley T, Foliono-Gallo P, Stephens P, van Ganse E (2005) Trends in prescribing and utilization of statins and other lipid lowering drugs across Europe 1997-2003. Br J Clin Pharmacol 60:543-551 (Pubitemid 41532455)
5. Ruokoniemi P, Helin-Salmivaara A, Klaukka T et al (2008) Shift of statin use towards the elderly in 1995-2005: A nation-wide register study in Finland. Br J Clin Pharmacol 66:405-410
6. Mantel-Teeuwisse AK, Kungel O, Schalekamp T et al (2005) Suboptimal choices and dosing of statins at start of therapy. Br J Clin Pharmacol 60:83-89 (Pubitemid 40942785)
7. Gislason GH, Rasmussen JN, Steen ZA et al (2007) Long-term compliance with beta-blockers, angiotensin-converting enzyme inhibitors, and statins after acute myocardial infarction. Eur Heart J 27:1153-1158
8. Geleedst-De Vooght M, Maitland-van der Zee AH, Schalekamp T et al (2010) Statin prescribing in the elderly in the Netherlands. A pharmacy database time trend study. Drugs Aging 27:589-596
9. Martikainen JE, Saastamoinen LK, Korhonen MJ et al (2010) Impact of restricted reimbursement on the use of statins in Finland. A register-based study. Med Care 48:761-766
10. Furu K, Wettermark B, Andersen M et al (2009) The Nordic countries as a cohort for pharmacoepidemiological research. Basic Clin Pharmacol Toxicol 106:86-94
11. Law MR, Wald NJ, Rudnicka AR (2003) Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: Systematic review and meta-analysis. Br Med J 326(7404):1423-1427 (Pubitemid 36776152)
12. SLD Pharma (2010) Finnish Pharmaceutical Data Ltd. Statistics 01/2010-11/2010. Finnish Pharmaceutical Data Ltd, Helsinki
13. Scandinavian Simvastatin Survival Study Group (1994) Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S). Lancet 344:1383-1389
14. Working group set up by the Finnish Medical Society Duodecim and the Finnish Society of Internal Medicine (2009) Dyslipidaemias. Current Care guideline. Finnish Medical Society Duodecim, Helsinki. Available at: Www.kaypahoito.fi. Accessed 1 Mar 2010
15. Smulders YM, Burgers JS, Scheltens T et al (2008) Clinical practice guideline for cardiovascular risk management in the Netherlands. Neth J Med 66(4):169-174 (Pubitemid 351593778)
16. Kiviniemi V, Peura P, Helin-Salmivaara A et al (2011) Statiinihoito aloitetaan simvastatiinilla pienin annoksin (in Finnish). Suom Lääkäril 66:568-571