Pressure hyperalgesia in hind limb suspended rats

Aviation Space and Environmental Medicine

Volumn 82, Issue 10, 2011, Pages 988-991

  Chowdhury, Parimal ^a   Soulsby, Michael E ^a   Jayroe, John ^a   Akel, Nisreen S ^a   Gaddy, Dana ^a   Dobretsov, Maxim ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Experimental microgravity; Hind limb unloading; Insulin; Neuropathy; Prediabetes; Pressure hyperalgesia

Indexed keywords

INSULIN;

ANIMAL; ARTICLE; BLOOD; HYPERALGESIA; IMMOBILIZATION; MALE; PAIN THRESHOLD; PANCREAS ISLET; PATHOLOGY; PRESSURE; RAT; SPRAGUE DAWLEY RAT; STATISTICAL MODEL;

ANIMALS; HINDLIMB SUSPENSION; HYPERALGESIA; INSULIN; ISLETS OF LANGERHANS; LINEAR MODELS; MALE; PAIN THRESHOLD; PRESSURE; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; RATTUS;

EID: 80054776518     PISSN: 00956562     EISSN: None     Source Type: Journal    
DOI: 10.3357/ASEM.3063.2011     Document Type: Article

References (11)

1. Chowdhury P, Soulsby M. Oxidant/anti-oxidant status in rats exposed to simulated weightlessness by hind-limb unloading and reloading. The Open Clinical Chemistry Journal 2008; 1: 47-56.
2. Dobretsov M, Backonja M, Romanovsky D, Stimers JR. Animal models of diabetic neuropathic pain. In: Ma C, Zhang J-M , eds. Animal models of pain. New York: Humana Press; 2010: 147-69.
3. Nichols KR, Chowdhury P, Dupont-Vesteegden EE. Pancreatic response to hind limb suspension in rats is affected by age. The Open Clinical Chemistry Journal 2008; 1: 69-74.
4. O'Neill S, Manniche C, Graven-Nielsen T, Arendt-Nielsen L. Generalized deep-tissue hyperalgesia in patients with chronic low-back pain. Eur J Pain 2007; 11: 415-20.
5. Romanovsky D, Walker JC, Dobretsov M. Pressure pain precedes development of type 2 disease in Zucker rat model of diabetes. Neurosci Lett 2008; 445: 220-3.
6. Romanovsky D, Wang J, Al Chaer ED, Stimers JR, Dobretsov M. Comparison of metabolic and neuropathy profiles of rats with streptozotocin-induced overt and moderate insulinopenia. Neuroscience 2010; 170: 337-47.
7. Simone DA, Marchettini P, Caputi G, Ochoa JL. Identification of muscle afferents subserving sensation of deep pain in humans. J Neurophysiol 1994; 72: 883-9.
8. Styf JR, Hutchinson K, Carlsson SG, Hargens AR. Depression, mood state, and back pain during microgravity simulated by bed rest. Psychosom Med 2001; 63: 862-4.
9. Tobin BW, Uchakin PN, Leeper-Woodford SK. Insulin secretion and sensitivity in space flight: diabetogenic effects. Nutrition 2002; 18: 842-8.
10. Tomlinson DR, Gardiner NJ. Glucose neurotoxicity. Nat Rev Neurosci 2008; 9: 36-45.
11. Ziegler MG, Meck JV. Physical and psychological challenges of space travel: an overview. Psychosom Med 2001; 63: 859-61.