Identification of oleamide in guatteria recurvisepala by LC/MS-based plasmodium falciparum thioredoxin reductase ligand binding method

Planta Medica

Volumn 77, Issue 15, 2011, Pages 1749-1753

  Munigunti, Ranjith ^a   Nelson, Nicholas ^a   Mulabagal, Vanisree ^a   Gupta, Mahabir P ^b   Brun, Reto ^c   Calderón, Angela I ^a  

^a AUBURN UNIVERSITY   (United States)

^b UNIVERSIDAD DE PANAMÁ   (Panama)

^c SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

Annonaceae; Chrysobalanaceae; Guatteria recurvisepala; Licania kallunkiae; liquid chromatography mass spectrometry; Melastomataceae; Plasmodium falciparum thioredoxin reductase (Pf TrxR); tandem MS; Topobea watsonii; ultrafiltration

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; FORMIC ACID; OLEAMIDE; PLANT EXTRACT; THIOREDOXIN REDUCTASE;

ANIMAL CELL; ANTIMALARIAL ACTIVITY; ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; CHRYSOBALANACEAE; CONTROLLED STUDY; CYTOTOXICITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG RETENTION; DRUG STRUCTURE; GUATTERIA; GUATTERIA RECURVISEPALA; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LICANIA KALLUNKIAE; LIGAND BINDING; LIQUID CHROMATOGRAPHY; MALARIA FALCIPARUM; MELASTOMATACEAE; NONHUMAN; PLASMODIUM FALCIPARUM; RAT; TANDEM MASS SPECTROMETRY; TOPOBEA WATSONII; ULTRAFILTRATION;

ANNONACEAE; CHRYSOBALANACEAE; GUATTERIA RECURVISEPALA; LICANIA; MELASTOMATACEAE; PLASMODIUM FALCIPARUM; TOPOBEA;

EID: 80054763443     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0030-1271080     Document Type: Article

References (16)

1. van Agtmael M A., Eggelte T A., van Boxtel C J. Artemisinin drugs in the treatment of malaria: from medicinal herb to registered medication. Trends Pharmacol Sci 1999 20 199-205
2. Balunas M J., Kinghorn A D. Drug discovery from medicinal plants. Life Sci 2005 78 431-441 (Pubitemid 41653493)
3. Andricopulo A D., Akoachere M B., Krogh R, Nickel C, McLeish M J., Kenyon G L., Arscott L D., Williams C H., Davioud-Charveta E, Beckerc K. Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents. Bioorg Med Chem Lett 2006 16 2283-2292 (Pubitemid 43351095)
4. Mulabagal V, Calderón A I. Development of binding assays to screen ligands for Plasmodium falciparum thioredoxin and glutathione reductases by ultrafiltration and liquid chromatography/mass spectrometry. J Chromatogr B 2010 878 987-993
5. Douglas W D. Flora de Nicaragua online. Available at http://mobot.mobot. org/W3T/Search/Nicaragua/projsflnic.html Accessed November 11, 2010
6. Maia J G. S., Andrade E H. A., Carreira L M. M., Oliveira J, Arajo J S. Essential oils of the Amazon Guatteria and Guatteriopsis species. Flavour Fragr J 2005 20 478-480 (Pubitemid 41288563)
7. Kanzok S M., Schirmer R H., Turbachova I, Iozef R, Becker K. The thioredoxin system of the malaria parasite Plasmodium falciparum. J Biol Chem 2000 275 40180-40186 (Pubitemid 32064647)
8. Bradford M M. A rapid and sensitive method for the quantitation of microgram quantities of proteins utilizing the principle of protein-dye binding. Anal Biochem 1976 72 248-254
9. Wall M E., Wani M C., Brown D M., Fullas F, Olwald J B., Josephson F F., Thornton N M., Pezzuto J M., Beecher C W. W. Effect of tannins on screening of plant extracts for enzyme inhibitory activity and techniques for their removal. Phytomedicine 1996 3 281-285 (Pubitemid 126504570)
10. Corbett Y, Herrera L, Cubilla L, Capson T L., Coley P D., Kursar T A., Romero L I., Ortega-Barra E. A novel DNA-based microfluorimetric method to evaluate antimalarial drug activity. Am J Trop Med Hyg 2004 70 119-124 (Pubitemid 38200513)
11. Matile H, Pink J R. L. Plasmodium falciparum malaria parasite cultures and their use in immunology. In: Lefkovits I Pernis B editors Immunological methods. Oxford Academic Press 1990 231-234
12. Kunert O, Swamy R C., Kaiser M, Presser A, Buzzi S, Appa Rao A V. N., Schühly W. Antiplasmodial and leishmanicidal activity of biflavonoids from Indian Selaginella bryopteris. Phytochem Lett 2009 1 171-174
13. Benjamin F C., Richard A L., Dale L B. Structure determination of an endogenous sleep-inducing lipid, cis-9-octadecenamide (oleamide): a synthetic approach to the chemical analysis of trace quantities of a natural product. J Am Chem Soc 1996 118 580-590
14. Milliken W. Malaria and antimalarial plants in Roraima, Brazil. Econ Bot 1997 51 212-237
15. Solomonia R, Kuchiashvili N, Berulava A, Pkhakadze V, Trapaidze N, Zhvania M, Abesadze I, Kojima H, Dalakishvili N. Purification and identification of components of the Aquilegia vulgaris extract fraction exhibiting anti-epileptic activity. J Biol Phys Chem 2004 4 185-192
16. Cheng M C., Ker Y B., Yu T H., Lin L Y., Peng R Y., Peng C H. Chemical synthesis of 9(Z)-octadecenamide and its hypolipidemic effect: a bioactive agent found in the essential oil of mountain celery seeds. J Agric Food Chem 2010 58 1502-1508