Acute toxicity studies of the aqueous root extract of Lawsonia inermis Linn. in rats

Journal of Medicinal Plant Research

Volumn 5, Issue 20, 2011, Pages 5123-5126

  Mudi, S Y ^a   Ibrahim, H ^b   Bala, M S ^a  

^a BAYERO UNIVERSITY   (Nigeria)

^b Federal College of Education (Technical)   (Nigeria)

Author keywords

Intraperitoneally; LD 50; Mortality; Spontaneous abortion; Temporary amnesia; Toxicity; Wister rats

Indexed keywords

LAWSONIA INERMIS EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG; VASOCONSTRICTOR AGENT;

AMNESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANOREXIA; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIZZINESS; DRUG SAFETY; FEMALE; LAWSONIA INERMIS; LD 50; MALE; MORTALITY; NONHUMAN; PARESIS; PHYSICAL ACTIVITY; PHYTOCHEMISTRY; PLANT ROOT; RAT; SPONTANEOUS ABORTION; TOXICITY TESTING;

LAWSONIA INERMIS; RATTUS;

EID: 80054760429     PISSN: None     EISSN: 19960875     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Aladesanmi AJ, Sofowora A, Leary JD (1986). Preliminary Biological and Phytochemical Investigation of two Nig. Medicinal Plants. Int. J. Crud Drug Res., 24(3): 147-153.
2. Brain KK, Turner TD (1975). The Practical Evaluation of Phytopharmaceuticals. Wright sciencechica. Bristol., pp. 57-58.
3. Ciulei I (1994). Methodology for Analysis of Vegetable Drugs. Chemical Industries branch Division of industrial operations, UNIDO; Romania; 24, 26 and 67.
4. Dalziel JM, Hutchinson JI (1958). Flora of Tropical West Africa. 1: (2). Crown Agent for overseas Government and Administration.
5. Fatope MO, Takeda Y (1988). Screening of Higher Plants Reputed as Pesticides using the Brine Shrimp Lethality Assay. Int. J. Pharmacognosy.
6. Fulder S (1988). Complementary Medicine. J. Clin. Herbal Med., 4(7): 12.
7. Hernedez C, Madrigal-Byaidar AC, Della Cruz C (2002). Inhibitory Effect of Chemical Essential Oil On the Chromatid Exchanged Induced Daurorubicin And Methyl Methane Sulfonate In Mouse Bone Marrow Anonymous. Ethno biology in India. A status report of all India coordinated Research project of ethno biology, Ministry of environment and forestry, Government of India (New Delhi).
8. th June, 2010.
9. Jallad KN, Espada-jallad C (2008). Lead Exposure from the use of L. inermis (Henna) in Temporary Paint-On-Tatooing and Hair Dying. Sci. Total Eviron., 397(1-3): 244-50.
10. Jovanovic DL, Slavkovic-jovanovic MR (2009). Allergic Contact Dermatitis from Temporary Henna Tatto. J. Dermatol., 36(1): 63-65.Link, http://www.scirus.com.
11. Munday R, Smith BL, Fowke EA (1991). Haemolytic activity and nephrotoxicity of 2-hydroxy-1,4-naphthoquinone in rats. J. Appl. Toxicol., 11: 85-90.Link: www.Cross Ref Web of Science Medline.
12. Munday R, Smith BL, Munday CM (1999a). Effect of Butylated Hydroxyanisole on the Toxicity of 2-Hydroxy-1,4-Naphthoquinone to Rats. Chem. Biol. Interact., 117: 241-256. Cross Ref Web of Science Medline.
13. Munday R, Smith BL, Munday CM (1999b). Effect of Inducers of DTDiaphorase on the Toxicity of 2-Methyl- And 2-Hydroxy-1, 4-Naphthoquinone to Rats. Chem. Biol. Interact., 123: 219-237. Cross Ref Webof Science Medline, www.wikepedia.com/lethaldose.
14. Nayak BS, Isitor G, Davis EM, Pillai GK (2007). The Evidence based Wound Healing Activity of L. inermis Linn. Phytother. Res., 21(9): 827-31.Link, http://www.scirus.com.
15. Polat M, Dikilitas M, Oztas P, Alli N (2009). Allergic Contact dermatitis to Pure Henna. Dermatol. Online J., 15(1): 15.Link, http://www.scirus.com.
16. Rates MSMK (2001). Plant as source of drugs. Toxicon., 7(4): 21-24
17. Saldanha CJ (1995). Flora of Karnataka. Volume 2, published by Oxford and IBH publishers. Link, http://www.ces.iisc.ernet.in/fish/pic/flora.html#LawsoniainermisL.
18. Sauriasari R, Wang DH, Takemura Y, Tsutsui K, Masuoka N, Sano K, Horita M, Wang BL Ogino K (2007). Cytotoxicity of Lawsone and Cytoprotective Activity of Antioxidants in Catalase Mutant Escherichia coli. Toxicol., 235(1-2): 103-111.
19. st edition. Med. Plants Trad. Med. Afr., pp.150-151 and 162-172.
20. Sultana N, Choudhary MI, Khan A (2009). Protein Glycation Inhibitory Activities of L. inermis and its Active Principles. J. Enzyme Inhib. Med. Chem., 24(1): 257-261.
21. 50 of The Aqueous Extract of Solanum nigrum Linn. in Rats. Best J., 1(2): 177-119.
22. Yucel I, Guzin G (2008). Tropical Henna for Capecitabine induced Hand-Foot Syndrome. Invest New Drugs, 26(2): 189-92.Link, http://www.scirus.com.