Models of Neurodegenerative Disease – Alzheimer’s Anatomical and Amyloid Plaque Imaging

Methods in Molecular Biology

Volumn 771, Issue , 2011, Pages 293-308

  Petiet, Alexandra ^a   Delatour, Benoit ^b   Dhenain, Marc ^c  

^a CNRS   (France)

^b Laboratoire de Neuropathologie Raymond Escourolle   (France)

^c Molecular Imaging Research Center   (France)

Author keywords

Animal model; APP, PS1; imaging; mouse, amyloid; MRI

Indexed keywords

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL; ARTICLE; BRAIN; DEGENERATIVE DISEASE; METHODOLOGY; MOUSE; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY;

ALZHEIMER DISEASE; ANIMALS; BRAIN; MAGNETIC RESONANCE IMAGING; MICE; NEURODEGENERATIVE DISEASES; PLAQUE, AMYLOID;

ANIMALIA; MUS;

EID: 80054752005     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-61779-219-9_16     Document Type: Chapter

References (24)

1. Hyman, B. T., Marzloff, K., and Arriagada, P. V. (1993) The lack of accumulation of senile plaques or amyloid burden in Alzheimer’s disease suggests a dynamic balance between amyloid deposition and resolution. J. Neuropath. Exp. Neur. 52, 594–600.
2. Jack, C. R., Jr., Lowe, V. J., Weigand, S. D., Wiste, H. J., Senjem, M. L., Knopman, D. S., Shiung, M. M., Gunter, J. L., Boeve, B. F., Kemp, B. J., Weiner, M., and Petersen, R. C. (2009) Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer’s disease: Implications for sequence of pathological events in Alzheimer’s disease. Brain 132, 1355–65.
3. Hardy, J., and Selkoe, D. J. (2002) The amyloid hypothesis of Alzheimer’s disease: Progress and problems on the road to therapeutics. Science 297, 353–6.
4. Blennow, K., de Leon, M. J., and Zetterberg, H. (2006) Alzheimer’s disease. Lancet 368, 387–403.
5. Duyckaerts, C., Potier, M. C., and Delatour, B. (2008) Alzheimer disease models and human neuropathology: Similarities and differences. Acta Neuropathol. 115, 5–38.
6. Delatour, B., Le Cudennec, C., El Tannir-El Tayara, N., and Dhenain, M. (2006) Transgenic models of Alzheimer’s pathology: Success and caveat. In Welsh, E. M. (Ed.), Topics in Alzheimer’s Disease, pp. 1–34. Nova Publishers, Happauge NY.
7. Delatour, B., Guegan, M., Volk, A., and Dhenain, M. (2006) In vivo MRI and histological evaluation of brain atrophy in APP/PS1 transgenic mice. Neurobiol. Aging 27, 835–47.
8. Valk, J., Barkhof, F., and Scheltens, P. (2002) Magnetic Resonance in Dementia. Springer, Heidelberg, Berlin, New York.
9. Albert, M., DeCarli, C., DeKosky, S., de Leon, M., Foster, N. L., Fox, N., Frank, R., Frackowiak, R., Jack, C., Jagust, W. J., Knopman, D., Morris, J. C., Petersen, R. C., Reiman, E., Scheltens, P., Small, G., Soini-nen, H., Thal, L., Wahlund, L.-O., Thies, W., Weiner, M. W., and Khachaturian, Z. (2005), Report of the neuroimaging work group of the Alzheimer’s Association. Available from http://www.alz.org/national/documents/Imaging_consensus_report.pdf.
10. Klunk, W. E., Lopresti, B. J., Ikonomovic, M. D., Lefterov, I. M., Koldamova, R. P., Abrahamson, E. E., Debnath, M. L., Holt, D. P., Huang, G. F., Shao, L., DeKosky, S. T., Price, J. C., and Mathis, C. A. (2005) Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer’s disease brain but not in transgenic mouse brain. J. Neurosci. 25, 10598–606.
11. El Tannir El Tayara, N., Delatour, B., Le Cudennec, C., Guegan, M., Volk, A., and Dhenain, M. (2006) Age-related evolution of amyloid burden, iron load, and MR relaxation times in a transgenic mouse model of Alzheimer’s disease. Neurobiol. Dis. 22, 199–208.
12. El Tayara Nel, T., Volk, A., Dhenain, M., and Delatour, B. (2007) Transverse relaxation time reflects brain amyloidosis in young APP/PS1 transgenic mice. Magn. Reson. Med. 58, 179–84.
13. Dhenain, M., Delatour, B., Walczak, C., and Volk, A. (2006) Passive staining: A novel ex vivo MRI protocol to detect amyloid deposits in mouse models of Alzheimer’s disease. Magn. Reson. Med. 55, 687–93.
14. Dhenain, M., El Tannir El Tayara, N., Wu, T.-D., Guegand, M., Volk, A., Quintana, C., and Delatour, B. (2009) Characterization of in vivo MRI detectable thalamic amyloid plaques from APP/PS1 mice. Neurobiol. Aging 30, 41–53.
15. Puchtler, H., Sweat, F., and Levine, M. (1962) On the binding of Congo red by amyloid. J. Histochem. Cytochem. 10, 355–64.
16. Nguyen-Legros, J., Bizot, J., Bolesse, M., and Pulicani, J.-P. (1980) “Noir de diaminobenzidine”: une nouvelle méthode histochimique de révélation du fer exogène (“Diaminobenzidine black”: A new histochemical method for the visualization of exogenous iron). Histochemistry 66, 239–44.
17. Petiet, A., Hedlund, L., and Johnson, G. A. (2007) Staining methods for magnetic resonance microscopy of the rat fetus. J. Magn. Reson. Imaging 25, 1192–8.
18. Faure, A., Verret, L., Bozon, B., El Tannir El Tayara, N., Ly, M., Kober, F., Dhenain, M., Rampon, C., and Delatour, B. (2011) Impaired neurogenesis, neuronal loss, and brain functional deficits in the APPxPS1-Ki mouse model of Alzheimer’s disease. Neurobiol. Aging 32(3), 407–418.
19. Le Cudennec, C., Faure, A., Ly, M., and Delatour, B. (2008) One-year longitudinal evaluation of sensorimotor functions in APP751SL transgenic mice. Genes Brain Behav. 7(Suppl 1), 83–91.
20. Delesse, M. A. (1847) Procédé mécanique pour déterminer la composition des roches [Mechanical process to evaluate the coomposition of rocks]. Comptes ren-dus de l’Académie des Sciences (Paris) 25, 544–45.
21. Masuda, T., Kasai, T., and Satodate, R. (1993) Quantitative measurement of hemosiderin deposition in tissue sections of the liver by image analysis. Anal. Quant. Cytol. Histol. 15, 379–82.
22. Turlin, B., Loreal, O., Moirand, R., Bris-sot, P., Deugnier, Y., and Ramee, M. P. (1992) Détection histochimique du fer hépa-tique (Histochemical detection of hepatic iron. A comparative study of four stains). Ann. Pathol. 12, 371–73.
23. Bizzi, A., Brooks, R. A., Brunetti, A., Hill, J. M., Alger, J. R., Miletich, R. S., Francavilla, T. L., and Di Chiro, G. (1990) Role of iron and ferritin in MR imaging of the brain: A study in primates at different field strengths. Radiology 177, 59–65.
24. Hill, J. M., and Switzer, R. C. (1984) The regional distribution and cellular localisation of iron in the rat brain. Neuroscience 11, 595–603.