Cdk5 targets active Src for ubiquitin-dependent degradation by phosphorylating Src(S75)

Cellular and Molecular Life Sciences

Volumn 68, Issue 20, 2011, Pages 3425-3436

  Pan, Q ^a   Qiao, F ^a   Gao, C ^a   Norman, B ^a   Optican, L ^a   Zelenka, Peggy S ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

Cdk5; Kinase activity; Signal transduction; Src; Ubiquitination

Indexed keywords

CYCLIN DEPENDENT KINASE 5; PROTEIN TYROSINE KINASE; UBIQUITIN;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME STABILITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; LENS EPITHELIUM; REGULATORY MECHANISM; UBIQUITINATION; WILD TYPE;

BLOTTING, WESTERN; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 5; ENZYME INHIBITORS; EPITHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOENZYME TECHNIQUES; LENS, CRYSTALLINE; MUTATION; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; UBIQUITIN; UBIQUITINATION;

EID: 80054744777     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-011-0638-1     Document Type: Article

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