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Volumn 67, Issue 47, 2011, Pages 9063-9066

Synthesis of 5-bromo-6-methyl imidazopyrazine, 5-bromo and 5-chloro-6-methyl imidazopyridine using electron density surface maps to guide synthetic strategy

(10) Harris, Anthony R a Nason, Deane M a Collantes, Elizabeth M a Xu, Wenjian a Chi, Yushi b Wang, Zhihan b Zhang, Bingzhi b Zhang, Qingjian b Gray, David L a Davoren, Jennifer E a

a PFIZER INC (United States)

b WUXI APPTEC (China)

Author keywords

Electron density surface maps; Electrophilic aromatic substitution; Imidazopyrazine; Imidazopyridine

Indexed keywords

5 BROMO 6 METHYL IMIDAZOPYRAZINE; 5 CHLORO 6 METHYL IMIDAZOPYRIDINE DERIVATIVE; IMIDAZOPYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DENSITY; ELECTRON; ELECTROPHILICITY; HYDROGEN BOND; HYDROLYSIS; IONIZATION; PRIORITY JOURNAL; SURFACE PROPERTY; SUZUKI REACTION; SYNTHESIS;

EID: 80054741781 PISSN: 00404020 EISSN: 14645416 Source Type: Journal
DOI: 10.1016/j.tet.2011.08.090 Document Type: Article

Times cited : (13)

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