Lymphocyte counts in kidney allograft recipients are associated with IMPDH2 3757T>C gene polymorphism

Transplantation Proceedings

Volumn 43, Issue 8, 2011, Pages 2943-2945

  Pazik, J ^a   Oldak M ^a   Podgorska M ^a   Lewandowski, Z ^a   Sitarek, E ^a   Ploski R ^a   Szmidt, J ^a   Chmura, A ^a   Durlik, M ^a   Malejczyk, J ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; INOSINATE DEHYDROGENASE; ISOENZYME; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

ACUTE GRAFT REJECTION; ADULT; CONFERENCE PAPER; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GASTROINTESTINAL SYMPTOM; GENE ACTIVITY; GENE FREQUENCY; GENOTYPE; HUMAN; INCIDENCE; KIDNEY ALLOGRAFT; KIDNEY TRANSPLANTATION; LYMPHOCYTE COUNT; LYMPHOCYTOPENIA; MAJOR CLINICAL STUDY; MALE; NEUTROPENIA; POLAND; POPULATION RESEARCH; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ALLELES; ANTILYMPHOCYTE SERUM; BASE SEQUENCE; DNA PRIMERS; FEMALE; GRAFT REJECTION; HUMANS; IMP DEHYDROGENASE; KIDNEY TRANSPLANTATION; LYMPHOCYTE COUNT; LYMPHOPENIA; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 80054737019     PISSN: 00411345     EISSN: 18732623     Source Type: Journal    
DOI: 10.1016/j.transproceed.2011.08.037     Document Type: Conference Paper

References (10)

1. P. Dalal, M. Grafals, and D. Chhabra Mycophenolate mofetil: safety and efficacy in the prophylaxis of acute kidney transplantation rejection Ther Clin Risk Manag 5 2009 139
2. A.G. Zimmermann, J.J. Gu, and J. Laliberte Inosine-50-monophosphate dehydrogenase: regulation of expression and role in cellular proliferation and T lymphocyte activation Prog Nucleic Acid Res Mol Biol 61 1998 181
3. T. Nguyen, J.Y. Park, and J.R. Scudiere Mycophenolic acid (cellcept and myofortic) induced injury of the upper GI tract Am J Surg Pathol 33 2009 1355
4. O. Gensburger, R.H. Van Schaik, and N. Picard Polymorphisms in type I and II inosine monophosphate dehydrogenase genes and association with clinical outcome in patients on mycophenolate mofetil Pharmacogenet Genomics 20 2010 537
5. J. Grinyó, Y. Vanrenterghem, and B. Nashan Association of four DNA polymorphisms with acute rejection after kidney transplantation Transpl Int 21 2008 879
6. A. Skórka, T. Bednarczuk, and E. Bar-Andziak Lymphoid tyrosine phosphatase (PTPN22/LYP) variant and Graves' disease in a Polish population: association and gene dose-dependent correlation with age of onset Clin Endocrinol (Oxf) 62 2005 679
7. S.A. Miller, D.D. Dykes, and H.F. Polesky A simple salting out procedure for extracting DNA from human nucleated cells Nucleic Acids Res 16 1988 1215
8. J. Wang, J.W. Yang, and A. Zeevi IMPDH1 gene polymorphisms and association with acute rejection in renal transplant patients Clin Pharmacol Ther 83 2008 711
9. F. Sombogaard, R.H. van Schaik, and R.A. Mathot Interpatient variability in IMPDH activity in MMF-treated renal transplant patients is correlated with IMPDH type II 3757T > C polymorphism Pharmacogenet Genomics 19 2009 626
10. W. Winnicki, G. Weigel, and G. Sunder-Plassmann An inosine 5′-monophosphate dehydrogenase 2 single-nucleotide polymorphism impairs the effect of mycophenolic acid Pharmacogenomics J 10 2010 70