-
1
-
-
0038394566
-
Precursor convertases in the secretory pathway, cytosol and extracellular milieu
-
Seidah, N. G., and Prat, A. (2002) Precursor convertases in the secretory pathway, cytosol and extracellular milieu Essays Biochem 38, 79–94.
-
(2002)
Essays Biochem
, vol.38
, pp. 79-94
-
-
Seidah, N. G.1
Prat, A.2
-
2
-
-
0033452452
-
Proprotein and prohormone convertases: A family of subtilases generating diverse bioactive polypeptides
-
Seidah, N. G., and Chrétien, M. (1999) Proprotein and prohormone convertases: A family of subtilases generating diverse bioactive polypeptides Brain Res 848, 45–62.
-
(1999)
Brain Res
, vol.848
, pp. 45-62
-
-
Seidah, N. G.1
Chrétien, M.2
-
3
-
-
0031995477
-
The proprotein convertases
-
Steiner, D. F. (1998) The proprotein convertases Curr Opin Chem Biol 2, 31–9.
-
(1998)
Curr Opin Chem Biol
, vol.2
, pp. 31-39
-
-
Steiner, D. F.1
-
4
-
-
0014146156
-
Evidence for a precursor in the biosynthesis of insulin
-
Steiner, D. F. (1967) Evidence for a precursor in the biosynthesis of insulin Trans NY Acad Sci 30, 60–8.
-
(1967)
Trans NY Acad Sci
, vol.30
, pp. 60-68
-
-
Steiner, D. F.1
-
5
-
-
0014107316
-
Isolation, purification, and characterization of gamma-lipotropic hormone from sheep pituitary glands
-
Chrétien, M., and Li, C. H. (1967) Isolation, purification, and characterization of gamma-lipotropic hormone from sheep pituitary glands Can J Biochem 45, 1163–74.
-
(1967)
Can J Biochem
, vol.45
, pp. 1163-1174
-
-
Chrétien, M.1
Li, C. H.2
-
6
-
-
58849114194
-
Peptide processing and biology in human disease
-
Kovac, S., Shulkes, A., and Baldwin, G. S. (2009) Peptide processing and biology in human disease Curr Opin Endocrinol Diabetes Obes 16, 79–85.
-
(2009)
Curr Opin Endocrinol Diabetes Obes
, vol.16
, pp. 79-85
-
-
Kovac, S.1
Shulkes, A.2
Baldwin, G. S.3
-
7
-
-
43049141452
-
The activation and physiological functions of the proprotein convertases
-
Seidah, N. G., Mayer, G., Zaid, A., Rousselet, E., Nassoury, N. et al. (2008) The activation and physiological functions of the proprotein convertases Int J Biochem Cell Biol 40, 1111–25.
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 1111-1125
-
-
Seidah, N. G.1
Mayer, G.2
Zaid, A.3
Rousselet, E.4
Nassoury, N.5
-
8
-
-
0025284946
-
cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: Tissue-specific mRNAs encoding candidates for prohormone processing proteinases DNA
-
Seidah, N. G., Gaspar, L., Mion, P., Marcinkiewicz, M., Mbikay, M., and Chrétien, M. (1990) cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: Tissue-specific mRNAs encoding candidates for prohormone processing proteinases DNA Cell Biol 9, 415–24.
-
(1990)
Cell Biol
, vol.9
, pp. 415-424
-
-
Seidah, N. G.1
Gaspar, L.2
Mion, P.3
Marcinkiewicz, M.4
Mbikay, M.5
Chrétien, M.6
-
9
-
-
0025214491
-
Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2
-
Smeekens, S. P., and Steiner, D. F. (1990) Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2 J Biol Chem 265, 2997–3000.
-
(1990)
J Biol Chem
, vol.265
, pp. 2997-3000
-
-
Smeekens, S. P.1
Steiner, D. F.2
-
10
-
-
0026348132
-
Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome DNA
-
Kiefer, M. C., Tucker, J. E., Joh, R., Landsberg, K. E., Saltman, D., and Barr, P. J. (1991) Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome DNA Cell Biol 10, 757–69.
-
(1991)
Cell Biol
, vol.10
, pp. 757-769
-
-
Kiefer, M. C.1
Tucker, J. E.2
Joh, R.3
Landsberg, K. E.4
Saltman, D.5
Barr, P. J.6
-
11
-
-
0025522624
-
Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes
-
van de Ven, W. J., Voorberg, J., Fontijn, R., Pannekoek, H., van den Ouweland, A. M., van Duijnhoven, H. L., Roebroek, A. J., and Siezen, R. J. (1990) Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes Mol Biol Rep 14, 265–75.
-
(1990)
Mol Biol Rep
, vol.14
, pp. 265-275
-
-
van de Ven, W. J.1
Voorberg, J.2
Fontijn, R.3
Pannekoek, H.4
van den Ouweland, A. M.5
van Duijnhoven, H. L.6
Roebroek, A. J.7
Siezen, R. J.8
-
12
-
-
0026785385
-
Testicular expression of PC4 in the rat: Molecular diversity of a novel germ cell-specific Kex2/subtilisin-like proprotein convertase
-
Seidah, N. G., Day, R., Hamelin, J., Gaspar, A., Collard, M. W., and Chrétien, M. (1992) Testicular expression of PC4 in the rat: Molecular diversity of a novel germ cell-specific Kex2/subtilisin-like proprotein convertase Mol Endocrinol 6, 1559–70.
-
(1992)
Mol Endocrinol
, vol.6
, pp. 1559-1570
-
-
Seidah, N. G.1
Day, R.2
Hamelin, J.3
Gaspar, A.4
Collard, M. W.5
Chrétien, M.6
-
13
-
-
0026660354
-
Identification of the fourth member of the mammalian endoprotease family homologous to the yeast Kex2 protease. Its testis-specific expression
-
Nakayama, K., Kim, W. S., Torii, S., Hosaka, M., Nakagawa, T., Ikemizu, J., Baba, T., and Murakami, K. (1992) Identification of the fourth member of the mammalian endoprotease family homologous to the yeast Kex2 protease. Its testis-specific expression J Biol Chem 267, 5897–900.
-
(1992)
J Biol Chem
, vol.267
, pp. 5897-5900
-
-
Nakayama, K.1
Kim, W. S.2
Torii, S.3
Hosaka, M.4
Nakagawa, T.5
Ikemizu, J.6
Baba, T.7
Murakami, K.8
-
14
-
-
0027274628
-
cDNA structure of the mouse and rat subtilisin/kexin-like PC5: A candidate proprotein convertase expressed in endocrine and nonendocrine cells
-
Lusson, J., Vieau, D., Hamelin, J., Day, R., Chrétien, M., and Seidah, N. G. (1993) cDNA structure of the mouse and rat subtilisin/kexin-like PC5: A candidate proprotein convertase expressed in endocrine and nonendocrine cells Proc Natl Acad Sci USA 90, 6691–5.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6691-6695
-
-
Lusson, J.1
Vieau, D.2
Hamelin, J.3
Day, R.4
Chrétien, M.5
Seidah, N. G.6
-
15
-
-
85152598664
-
Isolation of the human PC6 gene encoding the putative host protease for HIV-1 gp160 processing in CD4+ T lymphocytes
-
Miranda, L., Wolf, J., Pichuantes, S., Duke, R., and Franzusoff, A. (1996) Isolation of the human PC6 gene encoding the putative host protease for HIV-1 gp160 processing in CD4+ T lymphocytes Proc Natl Acad Sci USA 93, 7695–700.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7695-7700
-
-
Miranda, L.1
Wolf, J.2
Pichuantes, S.3
Duke, R.4
Franzusoff, A.5
-
16
-
-
0027376534
-
PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to
-
Rehemtulla, A., Barr, P. J., Rhodes, C. J., and Kaufman, R. J. (1993) PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE Biochemistry 32, 11586–90.
-
(1993)
PACE Biochemistry
, vol.32
, pp. 11586-11590
-
-
Rehemtulla, A.1
Barr, P. J.2
Rhodes, C. J.3
Kaufman, R. J.4
-
17
-
-
0029932186
-
PC8 [corrected], a new member of the convertase family
-
Bruzzaniti, A., Goodge, K., Jay, P., Taviaux, S. A., Lam, M. H., Berta, P., Martin, T. J., Moseley, J. M., and Gillespie, M. T. (1996) PC8 [corrected], a new member of the convertase family Biochem J 314, 727–31.
-
(1996)
Biochem J
, vol.314
, pp. 727-731
-
-
Bruzzaniti, A.1
Goodge, K.2
Jay, P.3
Taviaux, S. A.4
Lam, M. H.5
Berta, P.6
Martin, T. J.7
Moseley, J. M.8
Gillespie, M. T.9
-
18
-
-
0030029934
-
A new member of the proprotein convertase gene family (LPC) is located at a chromosome translocation breakpoint in lymphomas
-
Meerabux, J., Yaspo, M. L., Roebroek, A. J., Van de Ven, W. J., Lister, T. A., and Young, B. D. (1996) A new member of the proprotein convertase gene family (LPC) is located at a chromosome translocation breakpoint in lymphomas Cancer Res 56, 448–51.
-
(1996)
Cancer Res
, vol.56
, pp. 448-451
-
-
Meerabux, J.1
Yaspo, M. L.2
Roebroek, A. J.3
Van de Ven, W. J.4
Lister, T. A.5
Young, B. D.6
-
19
-
-
0029916795
-
cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases
-
Seidah, N. G., Hamelin, J., Mamarbachi, M., Dong, W., Tardos, H., Mbikay, M., Chrétien, M., and Day, R. (1996) cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases Proc Natl Acad Sci USA 93, 3388–93.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3388-3393
-
-
Seidah, N. G.1
Hamelin, J.2
Mamarbachi, M.3
Dong, W.4
Tardos, H.5
Mbikay, M.6
Chrétien, M.7
Day, R.8
-
20
-
-
13044279492
-
Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization
-
Seidah, N. G., Hamelin, J., Mamarbachi, A. M., Benjannet, S., Toure, B. B., Basak, A., Munzer, J. S., Marcinkiewicz, M., Zhong, M., Barale, J.-C., Lazure, C., Murphy, R. A., Chrétien, M., and Marcinkiewicz, M. (1999) Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization Proc Natl Acad Sci USA 96, 1321–6.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1321-1326
-
-
Seidah, N. G.1
Hamelin, J.2
Mamarbachi, A. M.3
Benjannet, S.4
Toure, B. B.5
Basak, A.6
Munzer, J. S.7
Marcinkiewicz, M.8
Zhong, M.9
Barale, J.-C.10
Lazure, C.11
Murphy, R. A.12
Chrétien, M.13
Marcinkiewicz, M.14
-
21
-
-
0033529545
-
Secreted site-1 protease cleaves peptides corresponding to luminal loop of sterol regulatory element-binding proteins
-
Cheng, D., Espenshade, P. J., Slaughter, C. A., Jaen, J. C., Brown, M. S., and Goldstein, J. L. (1999) Secreted site-1 protease cleaves peptides corresponding to luminal loop of sterol regulatory element-binding proteins J Biol Chem 274, 22805–12.
-
(1999)
J Biol Chem
, vol.274
, pp. 22805-22812
-
-
Cheng, D.1
Espenshade, P. J.2
Slaughter, C. A.3
Jaen, J. C.4
Brown, M. S.5
Goldstein, J. L.6
-
22
-
-
0037417807
-
The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiation
-
Seidah, N. G., Benjannet, S., Wickham, L., Marcinkiewicz, J., Bélanger Jasmin, S., Stifani, S., Basak, A., Prat, A., and Chrétien, M. (2003) The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiation Proc Natl Acad Sci USA 100, 928–33.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 928-933
-
-
Seidah, N. G.1
Benjannet, S.2
Wickham, L.3
Marcinkiewicz, J.4
Bélanger Jasmin, S.5
Stifani, S.6
Basak, A.7
Prat, A.8
Chrétien, M.9
-
23
-
-
0036083664
-
Proprotein convertases in tumor progression and malignancy: Novel targets in cancer therapy
-
Khatib, A. M., Siegfried, G., Chrétien, M., Metrakos, P., and Seidah, N. G. (2002) Proprotein convertases in tumor progression and malignancy: Novel targets in cancer therapy Am J Pathol 160, 1921–35.
-
(2002)
Am J Pathol
, vol.160
, pp. 1921-1935
-
-
Khatib, A. M.1
Siegfried, G.2
Chrétien, M.3
Metrakos, P.4
Seidah, N. G.5
-
24
-
-
27644521904
-
Proprotein convertases: “master switches” in the regulation of tumor growth and progression
-
Bassi, D. E., Fu, J., Lopez de Cicco, R., and Klein-Szanto, A. J. (2005) Proprotein convertases: “master switches” in the regulation of tumor growth and progression Mol Carcinog 44, 151–61.
-
(2005)
Mol Carcinog
, vol.44
, pp. 151-161
-
-
Bassi, D. E.1
Fu, J.2
Lopez de Cicco, R.3
Klein-Szanto, A. J.4
-
25
-
-
54349103245
-
Proprotein convertases as therapeutic targets
-
Chrétien, M., Seidah, N. G., Basak, A., and Mbikay, M. (2008) Proprotein convertases as therapeutic targets Expert Opin Ther Targets 12, 1289–300.
-
(2008)
Expert Opin Ther Targets
, vol.12
, pp. 1289-1300
-
-
Chrétien, M.1
Seidah, N. G.2
Basak, A.3
Mbikay, M.4
-
26
-
-
33750109567
-
Proprotein convertases: Lessons from knockouts
-
Scamuffa, N., Calvo, F., Chrétien, M., Seidah, N. G., and Khatib, A. M. (2006) Proprotein convertases: Lessons from knockouts FASEB J 20, 1954–63.
-
(2006)
FASEB J
, vol.20
, pp. 1954-1963
-
-
Scamuffa, N.1
Calvo, F.2
Chrétien, M.3
Seidah, N. G.4
Khatib, A. M.5
-
27
-
-
69249245353
-
Cellular and secreted pro-protein convertase subtilisin/kexin type 9 catalytic activity in hepatocytes
-
Kourimate, S., Chétiveaux, M., Jarnoux, A. L., Lalanne, F., and Costet, P. (2009) Cellular and secreted pro-protein convertase subtilisin/kexin type 9 catalytic activity in hepatocytes Atherosclerosis 206, 134–40.
-
(2009)
Atherosclerosis
, vol.206
, pp. 134-140
-
-
Kourimate, S.1
Chétiveaux, M.2
Jarnoux, A. L.3
Lalanne, F.4
Costet, P.5
-
28
-
-
70449368195
-
The unique role of proprotein convertase subtilisin/kexin 9 in cholesterol homeostasis
-
Mousavi, S. A., Berge, K. E., and Leren, T. P. (2009) The unique role of proprotein convertase subtilisin/kexin 9 in cholesterol homeostasis J Intern Med 266, 507–19.
-
(2009)
J Intern Med
, vol.266
, pp. 507-519
-
-
Mousavi, S. A.1
Berge, K. E.2
Leren, T. P.3
-
29
-
-
0036178061
-
Proprotein convertase PC5 regulation by PDGF-BB involves PI3-kinase/p70s6-kinase activation in vascular smooth muscle cells
-
Stawowy, P., Blaschke, F., Kilimnik, A., Goetze, S., Kallisch, H., Chrétien, M., Marcinkiewicz, M., Fleck, E., and Graf, K. (2002) Proprotein convertase PC5 regulation by PDGF-BB involves PI3-kinase/p70s6-kinase activation in vascular smooth muscle cells Hypertension 39, 399–404.
-
(2002)
Hypertension
, vol.39
, pp. 399-404
-
-
Stawowy, P.1
Blaschke, F.2
Kilimnik, A.3
Goetze, S.4
Kallisch, H.5
Chrétien, M.6
Marcinkiewicz, M.7
Fleck, E.8
Graf, K.9
-
30
-
-
33744954869
-
Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor
-
Ugleholdt, R., Poulsen, M. L., Holst, P. J., Irminger, J. C., Orskov, C., Pedersen, J., Rosenkilde, M. M., Zhu, X., Steiner, D. F., and Holst, J. J. (2006) Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor J Biol Chem 281, 11050–7.
-
(2006)
J Biol Chem
, vol.281
, pp. 11050-11057
-
-
Ugleholdt, R.1
Poulsen, M. L.2
Holst, P. J.3
Irminger, J. C.4
Orskov, C.5
Pedersen, J.6
Rosenkilde, M. M.7
Zhu, X.8
Steiner, D. F.9
Holst, J. J.10
-
31
-
-
60349109922
-
Proprotein convertase subtilisin/kexin type 4 in mammalian fertility: A review
-
Gyamera-Acheampong, C., and Mbikay, M. (2009) Proprotein convertase subtilisin/kexin type 4 in mammalian fertility: A review Hum Reprod Update 15, 237–47.
-
(2009)
Hum Reprod Update
, vol.15
, pp. 237-247
-
-
Gyamera-Acheampong, C.1
Mbikay, M.2
-
32
-
-
23344449205
-
Role of pro-IGF-II processing by proprotein convertase 4 in human placental development
-
Qiu, Q., Basak, A., Mbikay, M., Tsang, B. K., and Gruslin, A. (2005) Role of pro-IGF-II processing by proprotein convertase 4 in human placental development Proc Natl Acad Sci USA 102, 11047–52.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 11047-11052
-
-
Qiu, Q.1
Basak, A.2
Mbikay, M.3
Tsang, B. K.4
Gruslin, A.5
-
33
-
-
34547111271
-
Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens
-
Shiryaev, S. A., Remacle, A. G., Ratnikov, B. I., Nelson, N. A., Savinov, A. Y., Wei, G., Bottini, M., Rega, M. F., Parent, A., Desjardins, R., Fugere, M., Day, R., Sabet, M., Pellecchia, M., Liddington, R. C., Smith, J. W., Mustelin, T., Guiney, D. G., Lebl, M., and Strongin, A. Y. (2007) Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens J Biol Chem 282, 20847–53.
-
(2007)
J Biol Chem
, vol.282
, pp. 20847-20853
-
-
Shiryaev, S. A.1
Remacle, A. G.2
Ratnikov, B. I.3
Nelson, N. A.4
Savinov, A. Y.5
Wei, G.6
Bottini, M.7
Rega, M. F.8
Parent, A.9
Desjardins, R.10
Fugere, M.11
Day, R.12
Sabet, M.13
Pellecchia, M.14
Liddington, R. C.15
Smith, J. W.16
Mustelin, T.17
Guiney, D. G.18
Lebl, M.19
Strongin, A. Y.20
more..
-
34
-
-
36348972355
-
Site-1 protease is essential for endochondral bone formation in mice
-
Patra, D., Xing, X., Davies, S., Bryan, J., Franz, C., Hunziker, E. B., and Sandell, L. J. (2007) Site-1 protease is essential for endochondral bone formation in mice J Cell Biol 179, 687–700.
-
(2007)
J Cell Biol
, vol.179
, pp. 687-700
-
-
Patra, D.1
Xing, X.2
Davies, S.3
Bryan, J.4
Franz, C.5
Hunziker, E. B.6
Sandell, L. J.7
-
35
-
-
0029946619
-
SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis
-
Constam, D. B., Calfon, M., and Robertson, E. J. (1996) SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis J Cell Biol 134, 181–91.
-
(1996)
J Cell Biol
, vol.134
, pp. 181-191
-
-
Constam, D. B.1
Calfon, M.2
Robertson, E. J.3
-
36
-
-
33746216577
-
The proprotein convertases and their implication in sterol and/or lipid metabolism
-
Seidah, N. G., Khatib, A. M., and Prat, A. (2006) The proprotein convertases and their implication in sterol and/or lipid metabolism Biol Chem 387, 871–7.
-
(2006)
Biol Chem
, vol.387
, pp. 871-877
-
-
Seidah, N. G.1
Khatib, A. M.2
Prat, A.3
-
37
-
-
34247899771
-
The proprotein convertases are potential targets in the treatment of dyslipidemia
-
Seidah, N. G., and Prat, A. (2007) The proprotein convertases are potential targets in the treatment of dyslipidemia J Mol Med 85, 685–96.
-
(2007)
J Mol Med
, vol.85
, pp. 685-696
-
-
Seidah, N. G.1
Prat, A.2
-
38
-
-
0028089159
-
Proteolytic activation of bacterial toxins: Role of bacterial and host cell proteases
-
Gordon, V. M., and Leppla, S. H. (1994) Proteolytic activation of bacterial toxins: Role of bacterial and host cell proteases Infect Immun 62, 333–40.
-
(1994)
Infect Immun
, vol.62
, pp. 333-340
-
-
Gordon, V. M.1
Leppla, S. H.2
-
40
-
-
0001075710
-
Synthesis and chemistry of 7-amino-4-(trifluoromethyl) coumarin and its amino acid and peptide derivatives
-
Bissell, E. R., Mitchell, A. R., and Smith, R. E. (1980) Synthesis and chemistry of 7-amino-4-(trifluoromethyl) coumarin and its amino acid and peptide derivatives J Org Chem 45, 2283–7.
-
(1980)
J Org Chem
, vol.45
, pp. 2283-2287
-
-
Bissell, E. R.1
Mitchell, A. R.2
Smith, R. E.3
-
41
-
-
0024372389
-
Synthetic substrates for thrombin
-
Izquierdo, C., and Burguillo, J. (1989) Synthetic substrates for thrombin Int J Biochem 21, 579–92.
-
(1989)
Int J Biochem
, vol.21
, pp. 579-592
-
-
Izquierdo, C.1
Burguillo, J.2
-
42
-
-
38949127599
-
Calpain counteracts mechanosensitive apoptosis of vascular smooth muscle cells in vitro and in vivo
-
Sedding, D. G., Homann, M., Seay, U., Tillmanns, H., Preissner, K. T., and Braun-Dullaeus, R. C. (2008) Calpain counteracts mechanosensitive apoptosis of vascular smooth muscle cells in vitro and in vivo FASEB J 22, 579–89.
-
(2008)
FASEB J
, vol.22
, pp. 579-589
-
-
Sedding, D. G.1
Homann, M.2
Seay, U.3
Tillmanns, H.4
Preissner, K. T.5
Braun-Dullaeus, R. C.6
-
43
-
-
0032876070
-
Design, Synthesis, and characterization of 7-methoxy-4-(aminomethyl) coumarin as a novel and selective cytochrome P450 2D6 substrate suitable for high-throughput screening
-
Onderwater, R. C., Venhorst, J., Comman-deur, J. N., and Vermeulen, N. P. (1999) Design, Synthesis, and characterization of 7-methoxy-4-(aminomethyl) coumarin as a novel and selective cytochrome P450 2D6 substrate suitable for high-throughput screening Chem Res Toxicol 12, 555–9.
-
(1999)
Chem Res Toxicol
, vol.12
, pp. 555-559
-
-
Onderwater, R. C.1
Venhorst, J.2
Comman-deur, J. N.3
Vermeulen, N. P.4
-
44
-
-
0031398674
-
Endoproteases other than furin have a role in hepatic proprotein processing
-
Ledgerwood, E. C., Brennan, S. O., and George, P. M. (1997) Endoproteases other than furin have a role in hepatic proprotein processing IUBMB Life 42, 1131–42.
-
(1997)
IUBMB Life
, vol.42
, pp. 1131-1142
-
-
Ledgerwood, E. C.1
Brennan, S. O.2
George, P. M.3
-
45
-
-
0032692624
-
Proprotein convertase activity contributes to the processing of the Alzheimer’s β-amyloid precursor protein in human cells: Evidence for a role of the prohormone convertase PC7 in the constitutive α-secretase pathway
-
Lopez-Perez, E., Seidah, N. G., and Checler, F. (1999) Proprotein convertase activity contributes to the processing of the Alzheimer’s β-amyloid precursor protein in human cells: Evidence for a role of the prohormone convertase PC7 in the constitutive α-secretase pathway J Neurochem 73, 2056–62.
-
(1999)
J Neurochem
, vol.73
, pp. 2056-2062
-
-
Lopez-Perez, E.1
Seidah, N. G.2
Checler, F.3
-
46
-
-
33747636007
-
The proprotein convertase SKI-1/S1P. In vitro analysis of Lassa virus glycoprotein-derived substrates and ex vivo validation of irreversible peptide inhibitors
-
Pasquato, A., Pullikotil, P., Asselin, M. C., Vacatello, M., Paolillo, L., Ghezzo, F., Basso, F., Di Bello, C., Dettin, M., and Seidah, N. G. (2006) The proprotein convertase SKI-1/S1P. In vitro analysis of Lassa virus glycoprotein-derived substrates and ex vivo validation of irreversible peptide inhibitors J Biol Chem 281, 23471–81.
-
(2006)
J Biol Chem
, vol.281
, pp. 23471-23481
-
-
Pasquato, A.1
Pullikotil, P.2
Asselin, M. C.3
Vacatello, M.4
Paolillo, L.5
Ghezzo, F.6
Basso, F.7
Di Bello, C.8
Dettin, M.9
Seidah, N. G.10
-
47
-
-
0015529625
-
Liquid phase synthesis of peptides
-
Bayer, E., and Mutter, M. (1972) Liquid phase synthesis of peptides Nature 237, 512–13.
-
(1972)
Nature
, vol.237
, pp. 512-513
-
-
Bayer, E.1
Mutter, M.2
-
48
-
-
4344685947
-
Aminoethyl ben-zenesulfonyl fluoride and its hexapeptide (Ac-VFRSLK) conjugate are both in vitro inhibitors of subtilisin kexin isozyme-1
-
Basak, S., Stewart, N. A., Chrétien, M., and Basak, A. (2004) Aminoethyl ben-zenesulfonyl fluoride and its hexapeptide (Ac-VFRSLK) conjugate are both in vitro inhibitors of subtilisin kexin isozyme-1 FEBS Lett 573, 186–94.
-
(2004)
FEBS Lett
, vol.573
, pp. 186-194
-
-
Basak, S.1
Stewart, N. A.2
Chrétien, M.3
Basak, A.4
-
52
-
-
0036791359
-
Furin at the cutting edge: From protein traffic to embryogen- esis and disease
-
Thomas, G. (2002) Furin at the cutting edge: From protein traffic to embryogen- esis and disease Nat Rev Mol Cell Biol 3, 753–66.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 753-766
-
-
Thomas, G.1
-
53
-
-
62949138984
-
PC2/CPE-mediated proprotein processing in tumor cells and its differentiated cells or tissues
-
Tanga, S. S., Zhangc, J. H., Liud, H. X., and Li, H. Z. (2009) PC2/CPE-mediated proprotein processing in tumor cells and its differentiated cells or tissues Mol Cell Endocrinol 303, 43–9.
-
(2009)
Mol Cell Endocrinol
, vol.303
, pp. 43-49
-
-
Tanga, S. S.1
Zhangc, J. H.2
Liud, H. X.3
Li, H. Z.4
-
54
-
-
33947699375
-
A high performance liquid chromatography assay for monitoring proprotein convertase activity
-
Hall, T., Kam, F., Min, F., Liu, M., Zobel, J. F., Marino, M. H., Malfait, A. M., Tortorella, M. D., and Tomasselli, A. G. (2007) A high performance liquid chromatography assay for monitoring proprotein convertase activity J Chromatogr A 1148, 46–54.
-
(2007)
J Chromatogr A
, vol.1148
, pp. 46-54
-
-
Hall, T.1
Kam, F.2
Min, F.3
Liu, M.4
Zobel, J. F.5
Marino, M. H.6
Malfait, A. M.7
Tortorella, M. D.8
Tomasselli, A. G.9
-
55
-
-
51249091669
-
Proprotein convertase activation of aggrecanases in cartilage in situ
-
Malfait, A. M., Arner, E. C., Song, R. H., Alston, J. T., Markosyan, S., Staten, M., Yang, Z., Griggs, D. W., and Tortorella, M. D. (2008) Proprotein convertase activation of aggrecanases in cartilage in situ Arch Biochem Biophys 478, 43–51.
-
(2008)
Arch Biochem Biophys
, vol.478
, pp. 43-51
-
-
Malfait, A. M.1
Arner, E. C.2
Song, R. H.3
Alston, J. T.4
Markosyan, S.5
Staten, M.6
Yang, Z.7
Griggs, D. W.8
Tortorella, M. D.9
-
56
-
-
33746355249
-
Expression and characterization of constitutively active human caspase-14
-
Park, K., Kuechle, M. K., Choe, Y., Craik, C. S., Lawrence, O. Y., and Presland, R. B. (2006) Expression and characterization of constitutively active human caspase-14 Biochem Biophys Res Commun 347, 941–8.
-
(2006)
Biochem Biophys Res Commun
, vol.347
, pp. 941-948
-
-
Park, K.1
Kuechle, M. K.2
Choe, Y.3
Craik, C. S.4
Lawrence, O. Y.5
Presland, R. B.6
-
57
-
-
0025290914
-
A simple, combined fluorogenic and chromogenic method for the assay of proteases in gingival crevicular fluid
-
Cox, S. W., Cho, K., Eley, B. M., and Smith, R. E. (2006) A simple, combined fluorogenic and chromogenic method for the assay of proteases in gingival crevicular fluid J Periodontal Res 25, 164–71.
-
(2006)
J Periodontal Res
, vol.25
, pp. 164-171
-
-
Cox, S. W.1
Cho, K.2
Eley, B. M.3
Smith, R. E.4
-
58
-
-
0029945970
-
Biochemical characterization and ultrastructural localization of two extracellular trypsins produced by Metarhizium anisopliae in infected insect cuticles
-
St. Leger, R. J., Joshi, L., Bidochka, M. J., Rizzo, N. W., and Roberts, D. W. (1996) Biochemical characterization and ultrastructural localization of two extracellular trypsins produced by Metarhizium anisopliae in infected insect cuticles Appl Environ Microbiol 62, 1257–64.
-
(1996)
Appl Environ Microbiol
, vol.62
, pp. 1257-1264
-
-
St. Leger, R. J.1
Joshi, L.2
Bidochka, M. J.3
Rizzo, N. W.4
Roberts, D. W.5
-
59
-
-
0024820274
-
Detection of cathepsin B and L, elastase, tryptase, trypsin, and dipeptidyl peptidase IV-like activities in crevicular fluid from gingivitis and periodontitis patients with peptidyl derivatives of 7-amino-4-trifluoromethyl coumarin
-
Cox, S. W., and Eley, B. M. J. (1989) Detection of cathepsin B and L, elastase, tryptase, trypsin, and dipeptidyl peptidase IV-like activities in crevicular fluid from gingivitis and periodontitis patients with peptidyl derivatives of 7-amino-4-trifluoromethyl coumarin Periodontal Res 24, 353–1.
-
(1989)
Periodontal Res
, vol.24
, pp. 353-1
-
-
Cox, S. W.1
Eley, B. M. J.2
-
60
-
-
0029886649
-
The use of substrates with 7-amino-3-trifluoromethylcoumarine (AFC) leaving group in the localization of protease activities in situ
-
Lojda, Z. (1996) The use of substrates with 7-amino-3-trifluoromethylcoumarine (AFC) leaving group in the localization of protease activities in situ Acta Histochem 98, 215–28.
-
(1996)
Acta Histochem
, vol.98
, pp. 215-228
-
-
Lojda, Z.1
-
63
-
-
3543046713
-
Temporal regulation of VEID-7-amino-4-trifluoromethylcoumarin cleav-age activity and caspase-6 correlates with organelle loss during lens development
-
video journal: Cupp-Enyard, C. (2009), Use of the protease fluorescent detection kit to determine protease activity J Vis Exp 30
-
Foley, J. D., Rosenbaum, H., and Griep, A. E. (2004) Temporal regulation of VEID-7-amino-4-trifluoromethylcoumarin cleav-age activity and caspase-6 correlates with organelle loss during lens development J Biol Chem 279, 32142–50., and video journal: Cupp-Enyard, C. (2009), Use of the protease fluorescent detection kit to determine protease activity J Vis Exp 30; http://www. jove.com/index/Details.stp?ID=1514.
-
(2004)
J Biol Chem
, vol.279
, pp. 32142-32150
-
-
Foley, J. D.1
Rosenbaum, H.2
Griep, A. E.3
-
66
-
-
33845903845
-
Implantation serine proteinases heterodimerize and are critical in hatching and implantation
-
Sharma, N., Liu, S., Tang, L., Irwin, J., Meng, G., and Rancourt, D. E. (2006) Implantation serine proteinases heterodimerize and are critical in hatching and implantation BMC Dev Biol 6, 61–5.
-
(2006)
BMC Dev Biol
, vol.6
, pp. 61-65
-
-
Sharma, N.1
Liu, S.2
Tang, L.3
Irwin, J.4
Meng, G.5
Rancourt, D. E.6
-
68
-
-
0028924992
-
Fluorescence resonance energy transfer
-
Clegg, R. M. (1995) Fluorescence resonance energy transfer Curr Opin Biotechnol 6, 103–10.
-
(1995)
Curr Opin Biotechnol
, vol.6
, pp. 103-110
-
-
Clegg, R. M.1
-
69
-
-
8844220354
-
Positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides to define substrate specificity of carboxydipeptidases: Assays with human cathepsin
-
Cotrin, S. S., Puzer, L., de Souza, W. A., Juliano, J. L., Carmona, A. K., and Juliano, M. A. (2004) Positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides to define substrate specificity of carboxydipeptidases: Assays with human cathepsin Anal Biochem 335, 244–52.
-
(2004)
Anal Biochem
, vol.335
, pp. 244-252
-
-
Cotrin, S. S.1
Puzer, L.2
de Souza, W. A.3
Juliano, J. L.4
Carmona, A. K.5
Juliano, M. A.6
-
70
-
-
67649329734
-
Involvement of RNA-binding protein Hfq in the osmotic-response regulation of invE gene expression in Shigella sonne
-
Mitobe, J., Morita-Ishihara, T., Ishihama, A., and Watanabe, H. (2009) Involvement of RNA-binding protein Hfq in the osmotic-response regulation of invE gene expression in Shigella sonne BMC Microbiol 9, 110–16.
-
(2009)
BMC Microbiol
, vol.9
, pp. 110-116
-
-
Mitobe, J.1
Morita-Ishihara, T.2
Ishihama, A.3
Watanabe, H.4
-
71
-
-
0035253151
-
Implication of the proprotein convertases Furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and Respiratory Syncytial viruses – a comparative analysis using fluorogenic peptides
-
Basak, A., Zhong, M., Munzer, J. S., Chrétien, M., and Seidah, N. G. (2001) Implication of the proprotein convertases Furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and Respiratory Syncytial viruses – a comparative analysis using fluorogenic peptides Biochem J 353, 537–45.
-
(2001)
Biochem J
, vol.353
, pp. 537-545
-
-
Basak, A.1
Zhong, M.2
Munzer, J. S.3
Chrétien, M.4
Seidah, N. G.5
-
72
-
-
34248672821
-
A continuous fluorescence resonance energy transfer angiotensin I-converting enzyme assay
-
Carmona, A. K., Schwager, S. L., Juliano, M. A., Juliano, L., and Sturrock, E. D. (2006) A continuous fluorescence resonance energy transfer angiotensin I-converting enzyme assay Nat Protocol 1, 1971–6.
-
(2006)
Nat Protocol
, vol.1
, pp. 1971-1976
-
-
Carmona, A. K.1
Schwager, S. L.2
Juliano, M. A.3
Juliano, L.4
Sturrock, E. D.5
-
73
-
-
33748634622
-
Multibranch and Pseudopeptide approach for design of novel inhibitors of Subtilisin Kexin Isozyme-1
-
Basak, S., Mohottalage, D., and Basak, A. (2006) Multibranch and Pseudopeptide approach for design of novel inhibitors of Subtilisin Kexin Isozyme-1 Prot Pept Lett 13, 863–76.
-
(2006)
Prot Pept Lett
, vol.13
, pp. 863-876
-
-
Basak, S.1
Mohottalage, D.2
Basak, A.3
-
74
-
-
0026736344
-
Intramolecularly quenched fluorogenic peptide substrates for human rennin
-
Oliveira, M. C. F., Hirata, I. Y., Chagas, J. R., Boschcov, P., Gomes, R. A. S., Figueiredo, A. F. S., and Juliano, L. (1992) Intramolecularly quenched fluorogenic peptide substrates for human rennin Anal Biochem 203, 39–46.
-
(1992)
Anal Biochem
, vol.203
, pp. 39-46
-
-
Oliveira, M. C. F.1
Hirata, I. Y.2
Chagas, J. R.3
Boschcov, P.4
Gomes, R. A. S.5
Figueiredo, A. F. S.6
Juliano, L.7
-
75
-
-
0037228895
-
Fluorigenic substrates for the protease activities of botulinum neurotoxins, serotypes A, B, and F
-
James, J., Schmidt, J., and Robert, G. (2003) Fluorigenic substrates for the protease activities of botulinum neurotoxins, serotypes A, B, and F Appl Environ Microbiol 69, 297–303.
-
(2003)
Appl Environ Microbiol
, vol.69
, pp. 297-303
-
-
James, J.1
Schmidt, J.2
Robert, G.3
-
76
-
-
4744366997
-
Highly sensitive intramolecularly quenched fluorogenic substrates for renin based on the combination of L-2-amino-3-(7-methoxy-4-coumaryl) propionic acid with 2,4-dinitrophenyl groups at various positions
-
Paschalidou, K., Neumann, U., Gerhartz, B., and Tzougraki, C. (2004) Highly sensitive intramolecularly quenched fluorogenic substrates for renin based on the combination of L-2-amino-3-(7-methoxy-4-coumaryl) propionic acid with 2,4-dinitrophenyl groups at various positions Biochem J 382, 1031–8.
-
(2004)
Biochem J
, vol.382
, pp. 1031-1038
-
-
Paschalidou, K.1
Neumann, U.2
Gerhartz, B.3
Tzougraki, C.4
-
77
-
-
0035413605
-
Protein phosphatases – a phylogenetic perspective
-
Kennelly, P. J. (2001) Protein phosphatases – a phylogenetic perspective Chem Rev 101, 2291–312.
-
(2001)
Chem Rev
, vol.101
, pp. 2291-2312
-
-
Kennelly, P. J.1
-
79
-
-
85194798137
-
-
Rakhmanova, V., Po, P., and Meyer, R. Technical bulletin, A sensitive fluorimetric assay for detection of ß-secretase activity http://www.biocompare. com/Articles/ApplicationNote/1593/A-SensitiveFluorimetric-Assay-For-Detection-Of-Secretase-Activity.html.
-
Technical bulletin, A sensitive fluorimetric assay for detection of ß-secretase activity
-
-
Rakhmanova, V.1
Po, P.2
Meyer, R.3
-
80
-
-
84859106746
-
-
Diwu, Z., Xiang, Q., He, J., Zhang, J., Wang, H., Tang, Y., and Hong, A. (2005) Novel QXL-based protease substrates and their applications in drug discovery (http://www. anaspec.com/resources/publications.asp)
-
(2005)
Novel QXL-based protease substrates and their applications in drug discovery
-
-
Diwu, Z.1
Xiang, Q.2
He, J.3
Zhang, J.4
Wang, H.5
Tang, Y.6
Hong, A.7
-
81
-
-
70349345813
-
Development of a cell-based hepatitis C virus infection fluorescent resonance energy transfer assay for high-throughput antiviral compound screening
-
Yu, X., Sainz, B., Jr., and Uprichard, S. L. (2009) Development of a cell-based hepatitis C virus infection fluorescent resonance energy transfer assay for high-throughput antiviral compound screening Antimicrob Agents Chemother 53, 4311–19.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 4311-4319
-
-
Yu, X.1
Sainz, B.2
Uprichard, S. L.3
-
82
-
-
0018388950
-
Intramolecularly quenched fluorogenic substrates for hydrolytic enzymes
-
Yaron, A., Carmel, A., and Katchalski-Kazir, E. (1979) Intramolecularly quenched fluorogenic substrates for hydrolytic enzymes Anal Biochem 95, 228–35.
-
(1979)
Anal Biochem
, vol.95
, pp. 228-235
-
-
Yaron, A.1
Carmel, A.2
Katchalski-Kazir, E.3
-
83
-
-
0016378074
-
Autoradiographic assessment of proteolytic enzyme action using skeletal connective tissue matrices
-
Tonna, E. A., Aronson, R. B., and Pavelec, M. (1974) Autoradiographic assessment of proteolytic enzyme action using skeletal connective tissue matrices Connect Tissue Res 2, 183–91.
-
(1974)
Connect Tissue Res
, vol.2
, pp. 183-191
-
-
Tonna, E. A.1
Aronson, R. B.2
Pavelec, M.3
-
84
-
-
0041523879
-
Expanding the use of zymography by the chemical linkage of small, defined substrates to the gel matrix
-
Kaberdin, V. R., and McDowall, K. J. (2003) Expanding the use of zymography by the chemical linkage of small, defined substrates to the gel matrix Genome Res 13, 1961–5.
-
(2003)
Genome Res
, vol.13
, pp. 1961-1965
-
-
Kaberdin, V. R.1
McDowall, K. J.2
-
85
-
-
46149107630
-
Recombinant proprotein convertase 4 (PC4) from Leishmania tarentolae expression system: Purifica-tion, biochemical study and inhibitor design
-
Basak, A., Shervani, N. J., Mbikay, M., and Kolajova, M. (2008) Recombinant proprotein convertase 4 (PC4) from Leishmania tarentolae expression system: Purifica-tion, biochemical study and inhibitor design Protein Expr Purif 60, 117–26.
-
(2008)
Protein Expr Purif
, vol.60
, pp. 117-126
-
-
Basak, A.1
Shervani, N. J.2
Mbikay, M.3
Kolajova, M.4
-
86
-
-
0019174880
-
Development of a solid-phase assay for measurement of proteolytic enzyme activity
-
Varani, J., Johnson, K., and Kaplan, J. (1980) Development of a solid-phase assay for measurement of proteolytic enzyme activity Anal Biochem 107, 377–84.
-
(1980)
Anal Biochem
, vol.107
, pp. 377-384
-
-
Varani, J.1
Johnson, K.2
Kaplan, J.3
-
87
-
-
33645235785
-
Gold nanoparticles-based protease assay
-
Guarise, C., Pasquato, L., De Filippis, V., and Scrimin, P. (2006) Gold nanoparticles-based protease assay Proc Natl Acad Sci USA 103, 3978–82.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 3978-3982
-
-
Guarise, C.1
Pasquato, L.2
De Filippis, V.3
Scrimin, P.4
-
88
-
-
0033223445
-
Fluorescence-quenched solid phase combinatorial libraries in the characterization of cysteine protease substrate specificity
-
St Hilaire, P. M., Willert, M., Juliano, M. A., Juliano, L., and Meldal, M. (1999) Fluorescence-quenched solid phase combinatorial libraries in the characterization of cysteine protease substrate specificity J Comb Chem 1, 509–23.
-
(1999)
J Comb Chem
, vol.1
, pp. 509-523
-
-
St Hilaire, P. M.1
Willert, M.2
Juliano, M. A.3
Juliano, L.4
Meldal, M.5
-
91
-
-
1942489192
-
Development of a solid phase kinetic assay for determination of enzyme activities during composting
-
Peláez, C., Mejía, A., and Planas, A. (2004) Development of a solid phase kinetic assay for determination of enzyme activities during composting Process Biochem 39, 971–5.
-
(2004)
Process Biochem
, vol.39
, pp. 971-975
-
-
Peláez, C.1
Mejía, A.2
Planas, A.3
-
92
-
-
0037471238
-
Magnetic sensors for protease assays
-
Weissleder, R., Zhao, M., Josephson, L., and Tang, T. (2003) Magnetic sensors for protease assays Angew Chem Int Ed 42, 1375–8.
-
(2003)
Angew Chem Int Ed
, vol.42
, pp. 1375-1378
-
-
Weissleder, R.1
Zhao, M.2
Josephson, L.3
Tang, T.4
-
93
-
-
0025290569
-
A solid phase assay for the protease of human immunodeficiency virus
-
Wondrak, E. W., Copeland, T. D., Louis, J. M., and Oroszlan, S. (1990) A solid phase assay for the protease of human immunodeficiency virus Anal Biochem 188, 82–5.
-
(1990)
Anal Biochem
, vol.188
, pp. 82-85
-
-
Wondrak, E. W.1
Copeland, T. D.2
Louis, J. M.3
Oroszlan, S.4
-
94
-
-
0025863270
-
Detection of endopeptidase activity and analysis of cleavage specificity using a radiometric solid-phase enzymatic assay
-
Jean, F., Basak, A., Chrétien, M., and Lazure, C. (1991) Detection of endopeptidase activity and analysis of cleavage specificity using a radiometric solid-phase enzymatic assay Anal Biochem 194, 399–406.
-
(1991)
Anal Biochem
, vol.194
, pp. 399-406
-
-
Jean, F.1
Basak, A.2
Chrétien, M.3
Lazure, C.4
-
95
-
-
21644462358
-
Development of a solid-phase assay for analysis of matrix metalloproteinase activity
-
Janelle, L., Fields, L., Hideaki, N., and Fields, G. B. (2004) Development of a solid-phase assay for analysis of matrix metalloproteinase activity J Biomol Tech 15, 305–16.
-
(2004)
J Biomol Tech
, vol.15
, pp. 305-316
-
-
Janelle, L.1
Fields, L.2
Hideaki, N.3
Fields, G. B.4
-
97
-
-
23944500328
-
Aurora – A site specificity: Study with synthetic peptide substrates
-
Fearrari, S., Marin, O., Pagano, M. A., Meggio, F., Hess, D., and Shemerly, M. E. (2005) Aurora – A site specificity: Study with synthetic peptide substrates Biochem J 390, 293–302.
-
(2005)
Biochem J
, vol.390
, pp. 293-302
-
-
Fearrari, S.1
Marin, O.2
Pagano, M. A.3
Meggio, F.4
Hess, D.5
Shemerly, M. E.6
-
98
-
-
58149092026
-
Identification of small molecule binding molecules by affinity purification using a specific ligand immobilized on PEGA resin
-
Kuramochi, K., Miyano, Y., Enomoto, Y., Takeuchi, R., Ishi, K., Takakusagi, Y., Saitoh, T., Fukudome, K., Manita, D., Takeda, Y., Kobayashi, S., Sakaguchi, K., and Sugawara, F. (2008) Identification of small molecule binding molecules by affinity purification using a specific ligand immobilized on PEGA resin Bioconjug Chem 19, 2417–26.
-
(2008)
Bioconjug Chem
, vol.19
, pp. 2417-2426
-
-
Kuramochi, K.1
Miyano, Y.2
Enomoto, Y.3
Takeuchi, R.4
Ishi, K.5
Takakusagi, Y.6
Saitoh, T.7
Fukudome, K.8
Manita, D.9
Takeda, Y.10
Kobayashi, S.11
Sakaguchi, K.12
Sugawara, F.13
-
99
-
-
85194782340
-
Inhibition of chymotrypsin activity in crystalline trypsin preparations
-
Kostka, V., and Carpenter, F. H. (1964) Inhibition of chymotrypsin activity in crystalline trypsin preparations J Biol Chem 239, 2417–26.
-
(1964)
J Biol Chem
, vol.239
, pp. 2417-2426
-
-
Kostka, V.1
Carpenter, F. H.2
-
100
-
-
79959332503
-
Novel Circular, Cyclic and Acyclic (CH(2)O) Containing Peptide Inhibitors of SKI-1/S1P: Synthesis, Kinetic and Biochemical Evaluations
-
Majumdar, S., Chen, A., Palmer-Smith, H., and Basak, A. (2011) Novel Circular, Cyclic and Acyclic (CH(2)O) Containing Peptide Inhibitors of SKI-1/S1P: Synthesis, Kinetic and Biochemical Evaluations. Curr Med Chem. 18, 2770–82.
-
(2011)
Curr Med Chem
, vol.18
, pp. 2770-2782
-
-
Majumdar, S.1
Chen, A.2
Palmer-Smith, H.3
Basak, A.4
-
101
-
-
38449083342
-
Review article: Preeclamp-sia: A pressing problem: An executive summary of a national institute of child health and human development
-
Ilekis, J. V. (2007) Review article: Preeclamp-sia: A pressing problem: An executive summary of a national institute of child health and human development Workshop Reprod Sci 14, 508–23.
-
(2007)
Workshop Reprod Sci
, vol.14
, pp. 508-523
-
-
Ilekis, J. V.1
-
102
-
-
0141453694
-
Fetal growth restriction and consequences for the offspring in animal models
-
Holeman, K. (2003) Fetal growth restriction and consequences for the offspring in animal models J Soc Gynecol Invest 10, 392–9.
-
(2003)
J Soc Gynecol Invest
, vol.10
, pp. 392-399
-
-
Holeman, K.1
-
104
-
-
0014456911
-
Studies on Renin with synthetic substrates
-
Reinharz, A., and Roth M. (1969) Studies on Renin with synthetic substrates Eurp J Biochem 7, 334–9.
-
(1969)
Eurp J Biochem
, vol.7
, pp. 334-339
-
-
Reinharz, A.1
Roth, M.2
-
105
-
-
79952843364
-
-
Craik, C. S., Page, M. J., and Madison, E. L. (2011) Proteases as Therapeutics Biochem J 435, 1–16.
-
(2011)
Proteases as Therapeutics Biochem J
, vol.435
, pp. 1-16
-
-
Craik, C. S.1
Page, M. J.2
Madison, E. L.3
-
106
-
-
0026775916
-
Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen
-
Molloy, S. S., Bresnahan, P. A., Leppla, S. H., Klimpel, K. R., and Thomas, G. (1992) Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen J Biol Chem 267, 16396–402.
-
(1992)
J Biol Chem
, vol.267
, pp. 16396-16402
-
-
Molloy, S. S.1
Bresnahan, P. A.2
Leppla, S. H.3
Klimpel, K. R.4
Thomas, G.5
-
107
-
-
67650123226
-
Inhibition of furin/proprotein convertase-catalyzed surface and intracellular processing by small molecules
-
Komiyama, T., Coppola, J. M., Larsen, M. J., van Dort, M. E., Ross, B. D., Day, R., Rehemtulla, A., and Fuller, R. S. (2009) Inhibition of furin/proprotein convertase-catalyzed surface and intracellular processing by small molecules J Biol Chem 284, 15729–38.
-
(2009)
J Biol Chem
, vol.284
, pp. 15729-15738
-
-
Komiyama, T.1
Coppola, J. M.2
Larsen, M. J.3
van Dort, M. E.4
Ross, B. D.5
Day, R.6
Rehemtulla, A.7
Fuller, R. S.8
-
108
-
-
0030856553
-
In vitro characterization of the novel proprotein convertase PC7
-
Munzer, J. S., Basak, A., Zhong, M., Mamarbachi, A., Hamelin, J., Savaria, D., Lazure, C., Hendy, G. N., Benjannet, S., Chrétien, M., and Seidah, N. G. (1997) In vitro characterization of the novel proprotein convertase PC7 J Biol Chem 272, 19672–81.
-
(1997)
J Biol Chem
, vol.272
, pp. 19672-19681
-
-
Munzer, J. S.1
Basak, A.2
Zhong, M.3
Mamarbachi, A.4
Hamelin, J.5
Savaria, D.6
Lazure, C.7
Hendy, G. N.8
Benjannet, S.9
Chrétien, M.10
Seidah, N. G.11
-
109
-
-
4444279559
-
Prohormone convertase 1 (PC1) processing and sorting: Effect of PC1 propeptide and proSAAS
-
Lee, S. N., Prodhomme, E., and Lindberg, I. (2004) Prohormone convertase 1 (PC1) processing and sorting: Effect of PC1 propeptide and proSAAS J Endocrinol 182, 353–64.
-
(2004)
J Endocrinol
, vol.182
, pp. 353-364
-
-
Lee, S. N.1
Prodhomme, E.2
Lindberg, I.3
-
110
-
-
0037372081
-
The cystatin-related epididymal sper-matogenic protein inhibits the serine protease prohormone convertase
-
Cornwall, G. A., Cameron, A., Lindberg, I., Hardy, D. M., Cormier, N., and Hsia, N. (2003) The cystatin-related epididymal sper-matogenic protein inhibits the serine protease prohormone convertase Endocrinology 144(3), 901–8.
-
(2003)
Endocrinology
, vol.144
, Issue.3
, pp. 901-908
-
-
Cornwall, G. A.1
Cameron, A.2
Lindberg, I.3
Hardy, D. M.4
Cormier, N.5
Hsia, N.6
-
111
-
-
2942716755
-
In vitro elucidation of substrate specificity and bioassay of proprotein convertase 4 using intramolecularly quenched fluorogenic peptides
-
Basak, S., Chrétien, M., Mbikay, M., and Basak, A. (2004) In vitro elucidation of substrate specificity and bioassay of proprotein convertase 4 using intramolecularly quenched fluorogenic peptides Biochem J 380, 505–14.
-
(2004)
Biochem J
, vol.380
, pp. 505-514
-
-
Basak, S.1
Chrétien, M.2
Mbikay, M.3
Basak, A.4
-
112
-
-
0033215265
-
Enzymic characterization in vitro of recombinant proprotein convertase PC4
-
Basak, A., Touré, B. B., Lazure, C., Mbikay, M., Chrétien, M., and Seidah, N. G. (1999) Enzymic characterization in vitro of recombinant proprotein convertase PC4 Biochem J 343, 29–37.
-
(1999)
Biochem J
, vol.343
, pp. 29-37
-
-
Basak, A.1
Touré, B. B.2
Lazure, C.3
Mbikay, M.4
Chrétien, M.5
Seidah, N. G.6
-
113
-
-
0029135124
-
Fluorescent peptidyl substrates as an aid in studying the substrate specificity of human prohormone convertase PC1 and human furin and designing a potent irreversible inhibitor
-
Jean, F., Boudreault, A., Basak, A., Seidah, N. G., and Lazure, C. (1995) Fluorescent peptidyl substrates as an aid in studying the substrate specificity of human prohormone convertase PC1 and human furin and designing a potent irreversible inhibitor J Biol Chem 270, 19225–31.
-
(1995)
J Biol Chem
, vol.270
, pp. 19225-19231
-
-
Jean, F.1
Boudreault, A.2
Basak, A.3
Seidah, N. G.4
Lazure, C.5
-
114
-
-
24144450316
-
Protection from anthrax toxin-mediated killing of macrophages by the combined effects of furin inhibitors and Chloroquine
-
Komiyama, T., Swanson, J. A., and Fuller, R. S. (2005) Protection from anthrax toxin-mediated killing of macrophages by the combined effects of furin inhibitors and Chloroquine Antimicrob Agents Chemother 49, 3875–82.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 3875-3882
-
-
Komiyama, T.1
Swanson, J. A.2
Fuller, R. S.3
-
115
-
-
0037070601
-
A rapid fluorometric assay for the proteolytic activity of SKI-1/S1P based on the surface glycoprotein of the hemorrhagic fever Lassa virus
-
Basak, A., Chrétien, M., and Seidah, N. G. (2002) A rapid fluorometric assay for the proteolytic activity of SKI-1/S1P based on the surface glycoprotein of the hemorrhagic fever Lassa virus FEBS Let 514, 333–9.
-
(2002)
FEBS Let
, vol.514
, pp. 333-339
-
-
Basak, A.1
Chrétien, M.2
Seidah, N. G.3
-
116
-
-
0032575631
-
Specificity of prohormone convertase 2 on proenkephalin and proenkephalin-related substrates
-
Johanning, K., Juliano, M. A., Juliano, L., Lazure, C., Lamango, N. S., Steiner, D. F., and Lindberg, I. (1998) Specificity of prohormone convertase 2 on proenkephalin and proenkephalin-related substrates J Biol Chem 273, 22672–80.
-
(1998)
J Biol Chem
, vol.273
, pp. 22672-22680
-
-
Johanning, K.1
Juliano, M. A.2
Juliano, L.3
Lazure, C.4
Lamango, N. S.5
Steiner, D. F.6
Lindberg, I.7
|