메뉴 건너뛰기




Volumn 30, Issue 10, 2011, Pages 701-711

EGFR inhibitors sensitize non-small cell lung cancer cells to TRAIL-induced apoptosis

Author keywords

Epidermal growth factor receptor (egfr); Gene therapy; Non small cell lung cancer; Target therapy; Tumor necrosis factor re lated apoptosis in ducing ligand (trail)

Indexed keywords

ADENOVIRUS VECTOR; CETUXIMAB; ERLOTINIB; GEFITINIB; PROTEIN BAX; PROTEIN KINASE B; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 80054722876     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.011.10107     Document Type: Article
Times cited : (10)

References (34)
  • 1
    • 0034777482 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer is correlated with survival [J]
    • Brabender J, Danenberg KD, Metzger R, et al. Epidermal growth factor receptor and HER2-neu mRNA expression in non-small cell lung cancer is correlated with survival [J]. Clin Cancer Res, 2001,7(7):1850-1855.
    • (2001) Clin Cancer Res , vol.7 , Issue.7 , pp. 1850-1855
    • Brabender, J.1    Danenberg, K.D.2    Metzger, R.3
  • 2
    • 0031907022 scopus 로고    scopus 로고
    • Evaluation of epidermal growth factor-re lated growth factors and receptors and of neoangiogenesis in completely resected stage I -IIIA non-s mall-cell lung cancer: Amphiregulin and microvessel count are independent prognostic indicators of survival [J]
    • Fontanini G, De Laurentiis M, Vignati S, et al. Evaluation of epidermal growth factor-re lated growth factors and receptors and of neoangiogenesis in completely resected stage I -IIIA non-s mall-cell lung cancer: amphiregulin and microvessel count are independent prognostic indicators of survival [J]. Clin Cancer Res, 1998,4(1):241-249.
    • (1998) Clin Cancer Res , vol.4 , Issue.1 , pp. 241-249
    • Fontanini, G.1    de Laurentiis, M.2    Vignati, S.3
  • 3
    • 0030980781 scopus 로고    scopus 로고
    • Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does not predict tumor progression [J]
    • Rusch V, Klimstra D, Venkatraman E, et al. Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does not predict tumor progression [J]. Clin Cancer Res, 1997,3(4):515-522.
    • (1997) Clin Cancer Res , vol.3 , Issue.4 , pp. 515-522
    • Rusch, V.1    Klimstra, D.2    Venkatraman, E.3
  • 4
    • 0037296357 scopus 로고    scopus 로고
    • The epidermal growth factor receptor-tyrosine kinase: A promising therapeutic target in solid tumors [J]
    • Ritter CA, Arteaga CL. The epidermal growth factor receptor-tyrosine kinase: a promising therapeutic target in solid tumors [J]. Semin Oncol, 2003,30(1 Suppl):3-11.
    • (2003) Semin Oncol , vol.30 , Issue.1 , pp. 3-11
    • Ritter, C.A.1    Arteaga, C.L.2
  • 5
    • 65349116059 scopus 로고    scopus 로고
    • Cetuximab plus chemotherapy in patients with advanced non -small-cell lung cancer (FLEX): An open-la bel randomised phase III trial [J]
    • Pirker R, Pereira JR, Szczesna A, et al. Cetuximab plus chemotherapy in patients with advanced non -small-cell lung cancer (FLEX): an open-la bel randomised phase III trial [J]. Lancet, 2009,373(9674):1525-1531.
    • (2009) Lancet , vol.373 , Issue.9674 , pp. 1525-1531
    • Pirker, R.1    Pereira, J.R.2    Szczesna, A.3
  • 6
    • 37649022615 scopus 로고    scopus 로고
    • Randomized phase II study of gemcitabine plus cisplatin or carboplatin, with or without cetuximab, as first-lin e therapy for patients with advanced or metastatic non small-cell lung cancer [J]
    • Butts CA, Bodkin D, Middleman EL, et al. Randomized phase II study of gemcitabine plus cisplatin or carboplatin, with or without cetuximab, as first-lin e therapy for patients with advanced or metastatic non small-cell lung cancer [J]. J Clin Oncol, 2007,25(36):5777-5784.
    • (2007) J Clin Oncol , vol.25 , Issue.36 , pp. 5777-5784
    • Butts, C.A.1    Bodkin, D.2    Middleman, E.L.3
  • 7
    • 38849114239 scopus 로고    scopus 로고
    • Randomized phase II study of cetuximab plus cisplatin/vinorelbine compared with cisplatin/vinorelbine alone as first-lin e therapy in EGFR-expressing advanced non -small-cell lung cancer [J]
    • Rosell R, Robinet G, Szczesna A, et al. Randomized phase II study of cetuximab plus cisplatin/vinorelbine compared with cisplatin/vinorelbine alone as first-lin e therapy in EGFR-expressing advanced non -small-cell lung cancer [J]. Ann Oncol, 2008,19(2):362-369.
    • (2008) Ann Oncol , vol.19 , Issue.2 , pp. 362-369
    • Rosell, R.1    Robinet, G.2    Szczesna, A.3
  • 8
    • 0012381722 scopus 로고    scopus 로고
    • Multi-in stitutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [J]
    • Fukuoka M, Yano S, Giaccone G, et al. Multi-in stitutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [J]. J Clin Oncol, 2003,21(12):2237-2246.
    • (2003) J Clin Oncol , vol.21 , Issue.12 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3
  • 9
    • 0142055937 scopus 로고    scopus 로고
    • Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non -small cell lung cancer: A randomized trial [J]
    • Kris MG, Natale RB, Herbst RS, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non -small cell lung cancer: a randomized trial [J]. JAMA, 2003,290 (16):2149-2158.
    • (2003) JAMA , vol.290 , Issue.16 , pp. 2149-2158
    • Kris, M.G.1    Natale, R.B.2    Herbst, R.S.3
  • 10
    • 33644845421 scopus 로고    scopus 로고
    • First-lin e single agent treatment with gefitinib in patients with advanced non-small-cell lung cancer: A phase II study [J]
    • Niho S, Kubota K, Goto K, et al. First-lin e single agent treatment with gefitinib in patients with advanced non-small-cell lung cancer: a phase II study [J]. J Clin Oncol, 2006,24(1): 64-69.
    • (2006) J Clin Oncol , vol.24 , Issue.1 , pp. 64-69
    • Niho, S.1    Kubota, K.2    Goto, K.3
  • 11
    • 1542503746 scopus 로고    scopus 로고
    • Gefitinib in combination with gemcitabine and cisplatin in advanced non -small-cell lung cancer: A phase III trial-INTACT 1 [J]
    • Giaccone G, Herbst RS, Manegold C, et al. Gefitinib in combination with gemcitabine and cisplatin in advanced non -small-cell lung cancer: a phase III trial-INTACT 1 [J]. J Clin Oncol, 2004,22(5):777-784.
    • (2004) J Clin Oncol , vol.22 , Issue.5 , pp. 777-784
    • Giaccone, G.1    Herbst, R.S.2    Manegold, C.3
  • 12
    • 1542713370 scopus 로고    scopus 로고
    • Gefitinib in combination with paclitaxel and carboplatin in advanced non -small-cell lung cancer: A phase III trial-INTACT 2 [J]
    • Herbst RS, Giaccone G, Schiller JH, et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non -small-cell lung cancer: a phase III trial-INTACT 2 [J]. J Clin Oncol, 2004,22(5):785-794.
    • (2004) J Clin Oncol , vol.22 , Issue.5 , pp. 785-794
    • Herbst, R.S.1    Giaccone, G.2    Schiller, J.H.3
  • 13
    • 24944440830 scopus 로고    scopus 로고
    • TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-7 74) combined with carboplatin and paclitaxel chemotherapy in advanced non -small-c ell lung cancer [J]
    • Herbst RS, Prager D, Hermann R, et al. TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-7 74) combined with carboplatin and paclitaxel chemotherapy in advanced non -small-c ell lung cancer [J]. J Clin Oncol, 2005,23 (25):5892-5899.
    • (2005) J Clin Oncol , vol.23 , Issue.25 , pp. 5892-5899
    • Herbst, R.S.1    Prager, D.2    Hermann, R.3
  • 14
    • 34248140107 scopus 로고    scopus 로고
    • Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-s mall cell lung cancer: The Tarceva Lung Cancer Investigation trial [J]
    • Gatzemeier U, Pluzanska A, Szczesna A, et al. Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-s mall cell lung cancer: the Tarceva Lung Cancer Investigation trial [J]. J Clin Oncol, 2007,25(12):1545-1552.
    • (2007) J Clin Oncol , vol.25 , Issue.12 , pp. 1545-1552
    • Gatzemeier, U.1    Pluzanska, A.2    Szczesna, A.3
  • 15
    • 0035912060 scopus 로고    scopus 로고
    • Intracellular mechanisms of TRAIL: Apoptosis through mitochondrial-d ependent and -in dependent pathways [J]
    • Suliman A, Lam A, Datta R, et al. Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-d ependent and -in dependent pathways [J]. Oncogene, 2001,20 (17):2122-2133.
    • (2001) Oncogene , vol.20 , Issue.17 , pp. 2122-2133
    • Suliman, A.1    Lam, A.2    Datta, R.3
  • 16
    • 13344285339 scopus 로고
    • Identification and characterization of a new member of the TNF family that induces apoptosis[J]
    • Wiley SR, Schooley K, Smolak PJ, et al. Identification and characterization of a new member of the TNF family that induces apoptosis[J]. Immunity, 1995,3(6):673-682.
    • (1995) Immunity , vol.3 , Issue.6 , pp. 673-682
    • Wiley, S.R.1    Schooley, K.2    Smolak, P.J.3
  • 17
    • 0032713075 scopus 로고    scopus 로고
    • Safety and antitumor activity of recombinant soluble Apo2 ligand [J]
    • Ashkenazi A, Pai RC, Fong S, et al. Safety and antitumor activity of recombinant soluble Apo2 ligand [J]. J Clin Invest, 1999,104(2):155-162.
    • (1999) J Clin Invest , vol.104 , Issue.2 , pp. 155-162
    • Ashkenazi, A.1    Pai, R.C.2    Fong, S.3
  • 18
    • 0037418619 scopus 로고    scopus 로고
    • TRAIL-in duced signalling and apoptosis [J]
    • MacFarlane M. TRAIL-in duced signalling and apoptosis [J]. Toxicol Lett, 2003,139(2-3):89-97.
    • (2003) Toxicol Lett , vol.139 , Issue.2-3 , pp. 89-97
    • Macfarlane, M.1
  • 19
    • 0346792725 scopus 로고    scopus 로고
    • TRAIL and apoptosis induction by TNF-family death receptors [J]
    • Wang S, El-Deiry WS. TRAIL and apoptosis induction by TNF-family death receptors [J]. Oncogene, 2003,22(53):8628-8633.
    • (2003) Oncogene , vol.22 , Issue.53 , pp. 8628-8633
    • Wang, S.1    El-Deiry, W.S.2
  • 20
    • 0036020190 scopus 로고    scopus 로고
    • Antitumor activity and prolonged expression fromaTRAIL-e xpressing adenoviral vector [J]
    • Lee J, Hampl M, Albert P, et al. Antitumor activity and prolonged expression fromaTRAIL-e xpressing adenoviral vector [J]. Neoplasia, 2002,4(4):312-323.
    • (2002) Neoplasia , vol.4 , Issue.4 , pp. 312-323
    • Lee, J.1    Hampl, M.2    Albert, P.3
  • 21
    • 18744412616 scopus 로고    scopus 로고
    • Long-te rm tumor-free survival from treatment with the GFP-TRAIL fusion gene expressed from the hTERT promoter in breast cancer cells [J]
    • Lin T, Huang X, Gu J, Zhang L, et al. Long-te rm tumor-free survival from treatment with the GFP-TRAIL fusion gene expressed from the hTERT promoter in breast cancer cells [J]. Oncogene, 2002,21(52):8020-8028.
    • (2002) Oncogene , vol.21 , Issue.52 , pp. 8020-8028
    • Lin, T.1    Huang, X.2    Gu, J.3    Zhang, L.4
  • 22
    • 0348054562 scopus 로고    scopus 로고
    • Gene therapy of pancreatic cancer with green fluorescent protein and tumor necrosis factor-re lated apoptosis-in ducing ligand fusion gene expression driven by a human telomerase reverse transcriptase promoter [J]
    • Katz MH, Spivack DE, Takimoto S, et al. Gene therapy of pancreatic cancer with green fluorescent protein and tumor necrosis factor-re lated apoptosis-in ducing ligand fusion gene expression driven by a human telomerase reverse transcriptase promoter [J]. Ann Surg Oncol, 2003,10(7):762-772.
    • (2003) Ann Surg Oncol , vol.10 , Issue.7 , pp. 762-772
    • Katz, M.H.1    Spivack, D.E.2    Takimoto, S.3
  • 23
    • 34447294826 scopus 로고    scopus 로고
    • TRAIL therapy in non-s mall cell lung cancer cells: Sensitization to death receptor-m ediated apoptosis by proteasome inhibitor bortezomib [J]
    • Voortman J, Resende TP, Abou El Hassan MA, et al. TRAIL therapy in non-s mall cell lung cancer cells: sensitization to death receptor-m ediated apoptosis by proteasome inhibitor bortezomib [J]. Mol Cancer Ther, 2007,6(7):2103-2112.
    • (2007) Mol Cancer Ther , vol.6 , Issue.7 , pp. 2103-2112
    • Voortman, J.1    Resende, T.P.2    Abou, E.H.M.A.3
  • 24
    • 3042824992 scopus 로고    scopus 로고
    • Epidermal growth factor and trail interactions in epithelial-derived cells [J]
    • Gibson SB. Epidermal growth factor and trail interactions in epithelial-derived cells [J]. Vitam Horm, 2004,67:207-227.
    • (2004) Vitam Horm , vol.67 , pp. 207-227
    • Gibson, S.B.1
  • 25
    • 0035870294 scopus 로고    scopus 로고
    • Antitumor activity and bystander effects of the tumor necrosis factor-re lated apoptosis-in ducing ligand (TRAIL) gene [J]
    • Kagawa S, He C, Gu J, et al. Antitumor activity and bystander effects of the tumor necrosis factor-re lated apoptosis-in ducing ligand (TRAIL) gene [J]. Cancer Res, 2001,61(8):3330-3338.
    • (2001) Cancer Res , vol.61 , Issue.8 , pp. 3330-3338
    • Kagawa, S.1    He, C.2    Gu, J.3
  • 26
    • 0034022160 scopus 로고    scopus 로고
    • Apoptosis induced in normal human hepatocytes by tumor necrosis factor-re lated apoptosis-inducing ligand [J]
    • Jo M, Kim TH, Seol DW, et al. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-re lated apoptosis-inducing ligand [J]. Nat Med, 2000,6(5): 564-567.
    • (2000) Nat Med , vol.6 , Issue.5 , pp. 564-567
    • Jo, M.1    Kim, T.H.2    Seol, D.W.3
  • 27
    • 33748425912 scopus 로고    scopus 로고
    • Baseline gene expression predicts sensitivity to gefitinib in non-s mall cell lung cancer cell lines [J]
    • Coldren CD, Helfrich BA, Witta SE, et al. Baseline gene expression predicts sensitivity to gefitinib in non-s mall cell lung cancer cell lines [J]. Mol Cancer Res, 2006,4(8):521-528.
    • (2006) Mol Cancer Res , vol.4 , Issue.8 , pp. 521-528
    • Coldren, C.D.1    Helfrich, B.A.2    Witta, S.E.3
  • 28
    • 79959380355 scopus 로고    scopus 로고
    • Combination of vorinostat and adenovirus-TRAIL exhibitsa synergistic antitumor effect by increasing transduction and transcription of TRAIL in lung cancer cells [J]
    • Kim DR, Park MY, Lee CS, et al. Combination of vorinostat and adenovirus-TRAIL exhibitsa synergistic antitumor effect by increasing transduction and transcription of TRAIL in lung cancer cells [J]. Cancer Gene Ther, 2011,18(7):467-477.
    • (2011) Cancer Gene Ther , vol.18 , Issue.7 , pp. 467-477
    • Kim, D.R.1    Park, M.Y.2    Lee, C.S.3
  • 29
    • 0037081277 scopus 로고    scopus 로고
    • Epidermal growth factor protects epithelial-derived cells from tumor necrosis factor-re lated apoptosis-in ducing ligand-in duced apoptosis by inhibiting cytochrome c release [J]
    • Gibson EM, Henson ES, Haney N, et al. Epidermal growth factor protects epithelial-derived cells from tumor necrosis factor-re lated apoptosis-in ducing ligand-in duced apoptosis by inhibiting cytochrome c release [J]. Cancer Res, 2002,62(2): 488-496.
    • (2002) Cancer Res , vol.62 , Issue.2 , pp. 488-496
    • Gibson, E.M.1    Henson, E.S.2    Haney, N.3
  • 30
    • 0037085935 scopus 로고    scopus 로고
    • Requirement of BAX for TRAIL/Apo2L-in duced apoptosis of colorectal cancers: Synergism with sulindac-mediated inhibition of Bcl-x (L) [J]
    • Ravi R, Bedi A. Requirement of BAX for TRAIL/Apo2L-in duced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x (L) [J]. Cancer Res, 2002,62(6): 1583-1587.
    • (2002) Cancer Res , vol.62 , Issue.6 , pp. 1583-1587
    • Ravi, R.1    Bedi, A.2
  • 31
    • 0036064773 scopus 로고    scopus 로고
    • Regulation of Akt by EGF-R inhibitors, a possible mechanism of EGFR-R inhibitor-e nhanced TRAIL-induced apoptosis [J]
    • Park SY, Seol DW. Regulation of Akt by EGF-R inhibitors, a possible mechanism of EGFR-R inhibitor-e nhanced TRAIL-induced apoptosis [J]. Biochem Biophys Res Commun, 2002,295(2):515-518.
    • (2002) Biochem Biophys Res Commun , vol.295 , Issue.2 , pp. 515-518
    • Park, S.Y.1    Seol, D.W.2
  • 32
    • 77958473975 scopus 로고    scopus 로고
    • NF-B targeting by way of IKK inhibition sensitizes lung cancer cells to adenovirus delivery of TRAIL [J]
    • Aydin C, Sanlioglu AD, Bisgin A, et al. NF-B targeting by way of IKK inhibition sensitizes lung cancer cells to adenovirus delivery of TRAIL [J]. BMC Cancer, 2010,10:584.
    • (2010) BMC Cancer , vol.10 , pp. 584
    • Aydin, C.1    Sanlioglu, A.D.2    Bisgin, A.3
  • 33
    • 33947420511 scopus 로고    scopus 로고
    • Antibody-dependent cellular cytotoxicity mediated by cetuximab against lung cancer cell lines [J]
    • Kurai J, Chikumi H, Hashimoto K, et al. Antibody-dependent cellular cytotoxicity mediated by cetuximab against lung cancer cell lines [J]. Clin Cancer Res, 2007,13(5):1552-1561.
    • (2007) Clin Cancer Res , vol.13 , Issue.5 , pp. 1552-1561
    • Kurai, J.1    Chikumi, H.2    Hashimoto, K.3
  • 34
    • 33745059265 scopus 로고    scopus 로고
    • Chemotherapy-induced epidermal growth factor receptor activation determines response to combined gefitinib/chemotherapy treatment in non-small cell lung cancer cells [J]
    • Van Schaeybroeck S, Kyula J, Kelly DM, et al. Chemotherapy-induced epidermal growth factor receptor activation determines response to combined gefitinib/chemotherapy treatment in non-small cell lung cancer cells [J]. Mol Cancer Ther, 2006,5(5): 1154-1165.
    • (2006) Mol Cancer Ther , vol.5 , Issue.5 , pp. 1154-1165
    • van Schaeybroeck, S.1    Kyula, J.2    Kelly, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.