X chromosome association testing in genome wide association studies

Genetic Epidemiology

Volumn 35, Issue 7, 2011, Pages 664-670

  Hickey, Peter F ^a   Bahlo, Melanie ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Association test statistics; Genetic association studies; X linked markers

Indexed keywords

ARTICLE; CHROMOSOME ANALYSIS; CLINICAL STUDY; CONTROLLED STUDY; DISEASE MODEL; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; HUMAN; MALE; SEX RATIO; SIMULATION; X CHROMOSOME; X CHROMOSOME INACTIVATION;

CASE-CONTROL STUDIES; CHROMOSOMES, HUMAN, X; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MODELS, GENETIC; MODELS, STATISTICAL; PHENOTYPE; SEX RATIO;

EID: 80054722416     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20616     Document Type: Article

References (14)

1. Amos-Landgraf JM, Cottle A, Plenge RM, Friez M, Schwartz CE, Longshore J, Willard HF. 2006. X chromosome-inactivation patterns of 1, 005 phenotypically unaffected females. Am J Hum Genet 79:493-499.
2. Armitage P. 1955. Tests for linear trends in proportions and frequencies. Biometrics 11:375-386.
3. Chow JC, Yen Z, Ziesche SM, Brown CJ. 2005. Silencing of the mammalian X chromosome. Annu Rev Genomics Hum Genet 6:69-92.
4. Clayton D. 2008. Testing for association on the X chromosome. Biostatistics 9:593-600.
5. Clayton DG. 2009. Sex chromosomes and genetic association studies. Genome Med 1:110.
6. Clayton D, Leung H. 2010. snpMatrix: The snp.matrix and X.snp.matrix classes. R package version 1.12.0.
7. 2 tests. Biometrics 10:417-451.
8. Lettre G, Lange C, Hirschhorn JN. 2007. Genetic model testing and statistical power in population-based association studies of quantitative traits. Genet Epidemiol 31:358-62.
9. Ober C, Loisel DA, Gilad Y. 2008. Sex-specific genetic architecture of human disease. Nat Rev Genet 9:911-922.
10. Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, Bender D, Maller J, Sklar P, de Bakker, PIW, Daly MJ, Sham PC. 2007. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81:559-575.
11. R Development Core Team. 2009. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing. ISBN 3-900051-07-0.
12. Slager SL, Schaid DJ. 2001. Case-control studies of genetic markers: power and sample size approximations for Armitage's test for trend. Hum Hered 52:149-153.
13. Wilson EB. 1927. Probable inference, the law of succession, and statistical inference. J Am Stat Assoc 22:209-212.
14. Zheng G, Joo J, Zhang C, Geller NL. 2007. Testing association for markers on the X chromosome. Genet Epidemiol 31:834-843.