Comparison of metabolites in exhaled breath and bronchoalveolar lavage fluid samples in a mouse model of asthma

Journal of Applied Physiology

Volumn 111, Issue 4, 2011, Pages 1088-1095

  Neuhaus, Stephanie ^a   Seifert, Luzia ^b   Vautz, Wolfgang ^b   Nolte, Jürgen ^b   Bufe, Albrecht ^a   Peters, Marcus ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b LEIBNIZ INSTITUT FÜR ANALYTISCHE WISSENSCHAFTEN ISAS E V   (Germany)

Author keywords

Allergic airway inflammation; Ion mobility spectrometry

Indexed keywords

ARACHIDONIC ACID; HISTAMINE; NITRIC OXIDE;

ANIMAL; ARTICLE; ASTHMA; BAGG ALBINO MOUSE; CHEMISTRY; DISEASE MODEL; EXHALATION; FEMALE; GRANULOCYTE; INFLAMMATION; LUNG LAVAGE; METABOLISM; METHODOLOGY; MOUSE; PHYSIOLOGY; SPECTROSCOPY;

ANIMALS; ARACHIDONIC ACID; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE MODELS, ANIMAL; EXHALATION; FEMALE; GRANULOCYTES; HISTAMINE; INFLAMMATION; MICE; MICE, INBRED BALB C; NITRIC OXIDE; SPECTRUM ANALYSIS;

EID: 80054697380     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00476.2011     Document Type: Article

References (24)

1. Bloemen K, Van Den Heuvel R, Govarts E, Hooyberghs J, Nelen V, Witters E, Desager K, Schoeters G. A new approach to study exhaled proteins as potential biomarkers for asthma. Clin Exp Allergy 41: 346- 356, 2011.
2. Brown RH, Walters DM, Greenberg RS, Mitzner W. A method of endotracheal intubation and pulmonary functional assessment for repeated studies in mice. J Appl Physiol 87: 2362-2365, 1999.
3. Brussino L, Badiu I, Sciascia S, Bugiani M, Heffler E, Guida G, Malinovschi A, Bucca C, Rolla G. Oxidative stress and airway inflammation after allergen challenge evaluated by exhaled breath condensate analysis. Clin Exp Allergy 40: 1642-1647, 2010.
4. Bunkowski A, Bödeker B, Bader S, Westhoff M, Litterst P, Baumbach JI. MCC/IMS signals in human breath related to sarcoidosis-results of a feasibility study using an automated peak finding procedure. J Breath Res 3: 1-10, 2009.
5. Calhoun WJ, Reed HE, Moest DR, Stevens CA. Enhanced superoxide production by alveolar macrophages and air-space cells, airway inflammation, and alveolar macrophage density changes after segmental antigen bronchoprovocation in allergic subjects. Am Rev Respir Dis 145: 317-325, 1992.
6. Corradi M, Folesani G, Andreoli R, Manini P, Bodini A, Piacentini G, Carraro S, Zanconato S, Baraldi E. Aldehydes and glutathione in exhaled breath condensate of children with asthma exacerbation. Am J Respir Crit Care Med 167: 395-399, 2003. (Pubitemid 36216422)
7. Corradi M, Pignatti P, Manini P, Andreoli R, Goldoni M, Poppa M, Moscato G, Balbi B, Mutti A. Comparison between exhaled and sputum oxidative stress biomarkers in chronic airway inflammation. Eur Respir J 24: 1011-1017, 2004. (Pubitemid 39642294)
8. Hartmann M, Zimmermann D, Nolte J. Changes of the metabolism of the colon cancer cell line SW-480 under serum-free and serum-reduced growth conditions in vitro. Cell Dev Biol Anim 44: 458-463, 2008.
9. Idzko M, Hammad H, van Nimwegen M, Kool M, Willart MA, Muskens F, Hoogsteden HC, Luttmann W, Ferrari D, Di Virgilio F, Virchow JC Jr., Lambrecht BN. Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells. Nat Med 13: 913-919, 2007. (Pubitemid 47222044)
10. Jackson AS, Sandrini A, Campbell C, Chow S, Thomas PS, Yates DH. Comparison of biomarkers in exhaled breath condensate and bronchoalveolar lavage. Am J Respir Crit Care Med 175: 222-227, 2007. (Pubitemid 46203124)
11. Lázár Z, Cervenak L, Orosz M, Gálffy G, Komlósi ZI, Bikov A, Losonczy G, Horváth I. Adenosine triphosphate concentration of exhaled breath condensate in asthma. Chest 138: 536-542, 2010.
12. Naura AS, Zerfaoui M, Kim H, Abd Elmageed ZY, Rodriguez PC, Hans CP, Ju J, Errami Y, Park J, Ochoa AC, Boulares AH. Requirement for inducible nitric oxide synthase in chronic allergen exposureinduced pulmonary fibrosis but not inflammation. J Immunol 185: 3076- 3085, 2010.
13. Perl T, Carstens E, Hirn A, Quintel M, Vautz W, Nolte J, Jünger M. Determination of serum propofol concentrations by breath analysis using ion mobility spectrometry. Br J Anaesth 103: 822-827, 2009.
14. Peters M, Dudziak K, Stiehm M, Bufe A. T-cell polarization depends on concentration of the danger signal used to activate dendritic cells. Immunol Cell Biol 88: 537-544, 2010.
15. Peters M, Kauth M, Schwarze J, Korner-Rettberg C, Riedler J, Nowak D, Braun-Fahrländer C, von Mutius E, Bufe A, Holst O. Inhalation of stable dust extract prevents allergen induced airway inflammation and hyperresponsiveness. Thorax 61: 134-139, 2006. (Pubitemid 43235430)
16. Sanders SP, Zweier JL, Harrison SJ, Trush MA, Rembish SJ, Liu MC. Spontaneous oxygen radical production at sites of antigen challenge in allergic subjects. Am J Respir Crit Care Med 151: 1725-1733, 1995.
17. Soyer OU, Dizdar EA, Keskin O, Lilly C, Kalayci O. Comparison of two methods for exhaled breath condensate collection. Allergy 61: 1016-1018, 2006. (Pubitemid 44024902)
18. Vautz W, Baumbach JI. Exemplar application of multi-capillary column ion mobility spectrometry for biological and medical purpose. Int J Ion Mobility Spectrom 11: 35-41, 2008.
19. Vautz W, Baumbach JI, Jung J. Beer fermentation control using ion mobility spectrometry-Results of a pilot study. J Inst Brewing 112: 157-164, 2006. (Pubitemid 44326598)
20. Vautz W, Nolte J, Bufe A, Baumbach JI, Peters M. Analyses of mouse breath with ion mobility spectrometry: A feasibility study. J Appl Physiol 108: 697-704, 2010.
21. Vautz W, Nolte J, Fobbe R, Baumbach JI. Breath analysis performance and potential of ion mobility spectrometry. J Breath Res 3: 1-8, 2009.
22. Vautz W, Zimmermann D, Hartmann M, Baumbach JI, Nolte J, Jung J. Ion mobility spectrometry for food quality and safety. Food Addit Contam 23: 1064-1073, 2006. (Pubitemid 44650110)
23. Westhoff M, Litterst P, Freitag L, Urfer W, Bader S, Baumbach JI. Ion mobility spectrometry for the detection of volatile organic compounds in exhaled breath of patients with lung cancer: Results of a pilot study. Thorax 64: 744-748, 2009.
24. Wynalda KM, Murphy RC. Low-concentration ozone reacts with plasmalogen glycerophosphoethanolamine lipids in lung surfactant. Chem Res Toxicol 23: 108-117, 2010.