-
1
-
-
46049090201
-
Prevention of venous thromboembolism: American College of Chest Physicians evidence-based clinical practice guidelines (8th edition)
-
DOI 10.1378/chest.08-0656
-
Geerts WH, Bergquist D, Pineo GF, et al. Prevention of venous thromboembolism. American College of Chest Physicians evidence-based clinical practice guidelines (8th ed). Chest. 2008; 133:381S-453S (Pubitemid 351894916)
-
(2008)
Chest
, vol.133
, Issue.6 SUPPL. 6
-
-
Geerts, W.H.1
Bergqvist, D.2
Pineo, G.F.3
Heit, J.A.4
Samama, C.M.5
Lassen, M.R.6
Colwell, C.W.7
-
2
-
-
25844468887
-
-
European Medicines Agency March 17 [Last accessed 11 July 2011]
-
European Medicines Agency. Committee for Medicinal Products for Human Use Summary of Opinion. March 17, 2011. Available at: http://www.ema. europa.eu/docs/en-GB/document-library/Summary-of-opinion-Initial authorisation/human/002148/WC500103875.pdf [Last accessed 11 July 2011]
-
(2011)
Committee for Medicinal Products for Human Use Summary of Opinion
-
-
-
3
-
-
84862769013
-
-
Pharm Info website [Last accessed 11 April 2011]
-
Pharm Info website. Available at: http://pharminfo.co.cc/2010/10/ bmsinitiated-apixaban-filing-for-fda-approval/#more-2812 [Last accessed 11 April 2011]
-
-
-
-
4
-
-
84862775668
-
-
Drug Info Pipeline website [Last accessed 11 July 2011]
-
Drug Info Pipeline website. Available at: http://www. drugpipelineforecast. com/pipeline/product.html?id1/4236305df-8506-4392-8657- eb37d26cd8b9-Eliquis-apixaban [Last accessed 11 July 2011]
-
-
-
-
5
-
-
84862775669
-
-
Press release [Last accessed 11 April 2011]
-
Press release. Available at: http://www.jnjpharmarnd.com/jnjpharmarnd/ assets/Rivaroxaban-Filing%20for%20SPAF%20Press%20ReleasËFINAL. pdf#zoom1/4100 [Last accessed 11 April 2011]
-
-
-
-
6
-
-
84862767750
-
-
Bayer website [Last accessed 11 April 2011]
-
Bayer website. Rivaroxaban. Available at: http://www.bayer.com/en/ bayerhealthcare. aspx [Last accessed 11 April 2011]
-
Rivaroxaban
-
-
-
7
-
-
84862773006
-
-
Betrixaban News Release [Last accessed 11 April 2011]
-
Betrixaban News Release. Available at: http://www.portola.com/pdfs/ Betrixaban-Release.pdf [Last accessed 11 April 2011]
-
-
-
-
8
-
-
84862762044
-
-
Astellas News Release [Last accessed 11 April 2011]
-
Astellas News Release. Available at: http://www.astellas.com/en/ corporate/news/pdf/110215-eg.pdf [Last accessed 11 April 2011]
-
-
-
-
9
-
-
84862762047
-
-
Daiichi Sankyo News Release [Last accessed 30 April 2011]
-
Daiichi Sankyo News Release. Available at: http://www.daiichisankyo.com/ news/detail/004033.html [Last accessed 30 April 2011]
-
-
-
-
10
-
-
84862756823
-
-
FDA News Release [Last accessed 11 April 2011]
-
FDA News Release. Dabigatran. Available at: http://www.fda.gov/News Events/Newsroom/PressAnnouncements/ucm230241.htm [Last accessed 11 April 2011]
-
Dabigatran
-
-
-
11
-
-
60849097858
-
A randomized evaluation of betrixaban, an oral factor Xa inhibitor, for prevention of thromboembolic events after total knee replacement (EXPERT)
-
for the EXPERT Study Group
-
Turpie AG, Bauer KA, Davidson BL, et al. for the EXPERT Study Group. A randomized evaluation of betrixaban, an oral factor Xa inhibitor, for prevention of thromboembolic events after total knee replacement (EXPERT). Thromb Haemost 2009;101:68-76
-
(2009)
Thromb Haemost
, vol.101
, pp. 68-76
-
-
Turpie, A.G.1
Bauer, K.A.2
Davidson, B.L.3
-
12
-
-
35449007749
-
Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: The RE-MODEL randomized trial
-
DOI 10.1111/j.1538-7836.2007.02748.x
-
Eriksson BI, Dahl OE, Rosencher N, et al. Dabigatran etexilate versus enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RËMODEL randomized trial. J Thromb Hemost 2007;5:2178-85 (Pubitemid 47617868)
-
(2007)
Journal of Thrombosis and Haemostasis
, vol.5
, Issue.11
, pp. 2178-2185
-
-
Eriksson, B.I.1
Dahl, O.E.2
Rosencher, N.3
Kurth, A.A.4
Van Dijk, C.N.5
Frostick, S.P.6
Kalebo, P.7
Christiansen, A.V.8
Hantel, S.9
Hettiarachchi, R.10
Schnee, J.11
Buller, H.R.12
-
13
-
-
57649123692
-
Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery
-
Ginsberg JS, Davidson BL, Comp PC, et al. Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery. J Arthroplasty 2009; 24:1-9
-
(2009)
J Arthroplasty
, vol.24
, pp. 1-9
-
-
Ginsberg, J.S.1
Davidson, B.L.2
Comp, P.C.3
-
16
-
-
79961034650
-
Edoxaban versus enoxaparin for thromboprophylaxis after total knee replacement: The STARS E-3 trial
-
July 6-9 Milano, Italy
-
Fuji T, et al. Edoxaban versus enoxaparin for thromboprophylaxis after total knee replacement: The STARS E-3 trial. 21st International Congress of Thrombosis, July 6-9 2010, Milano, Italy
-
(2010)
21st International Congress of Thrombosis
-
-
Fuji, T.1
-
17
-
-
45949103416
-
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty
-
DOI 10.1056/NEJMoa076016
-
Lassen MR, Ageno W, Borris LC, et al. for the RECORD3 Investigators. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty. N Engl J Med 2008;358:2776-86 (Pubitemid 351930852)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.26
, pp. 2776-2786
-
-
Lassen, M.R.1
Ageno, W.2
Borris, L.C.3
Lieberman, J.R.4
Rosencher, N.5
Bandel, T.J.6
Misselwitz, F.7
Turpie, A.G.G.8
-
18
-
-
65549169515
-
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): A randomised trial
-
for the RECORD4 Investigators
-
Turpie AG, Lassen MR, Davidson BL, et al. for the RECORD4 Investigators. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): a randomised trial. Lancet 2009;373:1673-80
-
(2009)
Lancet
, vol.373
, pp. 1673-80
-
-
Turpie, A.G.1
Lassen, M.R.2
Davidson, B.L.3
-
19
-
-
63049119668
-
AVE5026, a new hemisynthetic ultralow-molecular-weight heparin for the prevention of venous thromboembolism in patients after total knee replacement surgery-TREK: A dose-ranging study
-
Lassen MR, Dahl OE, Mismetti P, et al. AVE5026, a new hemisynthetic ultralow-molecular-weight heparin for the prevention of venous thromboembolism in patients after total knee replacement surgery-TREK: a dose-ranging study. J Thromb Haemost 2009;7:566-72
-
(2009)
J Thromb Haemost
, vol.7
, pp. 566-572
-
-
Lassen, M.R.1
Dahl, O.E.2
Mismetti, P.3
-
21
-
-
77953394559
-
Recombinant antidote for reversal of anticoagulation by factor Xa inhibitors [abstract]
-
Abstract 983
-
Lu G, DeGuzman FR, Lakhotia S, et al. Recombinant antidote for reversal of anticoagulation by factor Xa inhibitors [abstract]. Blood 2008;112(11): Abstract 983
-
(2008)
Blood
, vol.112
, Issue.11
-
-
Lu, G.1
Deguzman, F.R.2
Lakhotia, S.3
-
22
-
-
42149172523
-
Apixaban, an oral, direct and highly selective factor Xa inhibitor: In vitro, antithrombotic and antihemostatic studies
-
DOI 10.1111/j.1538-7836.2008.02939.x
-
Wong PC, Crain EJ, Xin RR, et al. Apixaban, an oral direct and highly selective factor Xa inhibitor: in vitro antithrombotic and antihemostatic studies. J Thromb Haemost 2007;6:820-9 (Pubitemid 351524543)
-
(2008)
Journal of Thrombosis and Haemostasis
, vol.6
, Issue.5
, pp. 820-829
-
-
Wong, P.C.1
Crain, E.J.2
Xin, B.3
Wexler, R.R.4
Lam, P.Y.S.5
Pinto, D.J.6
Luettgen, J.M.7
Knabb, R.M.8
-
23
-
-
58149458160
-
Apixaban metabolism and pharmacokinetics after oral administration to humans
-
Raghavan N, Frost CE, Yu Z, et al. Apixaban metabolism and pharmacokinetics after oral administration to humans. Drug Metab Dispos 2009;37: 74-81
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 74-81
-
-
Raghavan, N.1
Frost, C.E.2
Yu, Z.3
-
24
-
-
67650809062
-
Comparative metabolism of 14C-labeled apixaban in mice, rats, rabbits, dogs, and humans
-
Zhang D, He K, Raghavan N, et al. Comparative metabolism of 14C-labeled apixaban in mice, rats, rabbits, dogs, and humans. Drug Metab Dispos 2009;37:1738-48
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 1738-48
-
-
Zhang, D.1
He, K.2
Raghavan, N.3
-
25
-
-
34548031359
-
The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects
-
DOI 10.1111/j.1365-2125.2007.02899.x
-
Stangier J, Rathgen K. Stahle H, et al. The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects. Br J Clin Pharmacol 2007;64:292-303 (Pubitemid 47283865)
-
(2007)
British Journal of Clinical Pharmacology
, vol.64
, Issue.3
, pp. 292-303
-
-
Stangier, J.1
Rathgen, K.2
Stahle, H.3
Gansser, D.4
Roth, W.5
-
26
-
-
84862775667
-
-
Dabigatran (Pradaxa) [package insert]. Ridgefield CT: Boehringer Ingelheim Pharmaceuticals Inc. 2011 [Last accessed 9 April 2011]
-
Dabigatran (Pradaxa) [package insert]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc., 2011. Available at: http://bidocs. boehringeringelheim. com/BIWebAccess/ViewServlet.ser?docBase1/ 4renetnt&folderPath1/4/Prescribing%20Information/PIs/Pradaxa/Pradaxa.pdf [Last accessed 9 April 2011]
-
-
-
-
27
-
-
29144518504
-
Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939 - An oral, direct Factor Xa inhibitor - After multiple dosing in healthy male subjects
-
DOI 10.1007/s00228-005-0043-5
-
Kubitza D, Becka M, Wensing G, et al. Safety, pharmacodynamics, and pharmacokinetics of BAY 59-7939-an oral, direct Factor Xa inhibitor-after multiple dosing in healthy male subjects. Eur J Clin Pharmacol 2005; 61:873-80 (Pubitemid 41803696)
-
(2005)
European Journal of Clinical Pharmacology
, vol.61
, Issue.12
, pp. 873-880
-
-
Kubitza, D.1
Becka, M.2
Wensing, G.3
Voith, B.4
Zuehlsdorf, M.5
-
28
-
-
57449094606
-
Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development
-
Eriksson BI, Quinlan DJ, Weitz JI. Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development. Clin Pharmacokinet 2009;48:1-22
-
(2009)
Clin Pharmacokinet
, vol.48
, pp. 1-22
-
-
Eriksson, B.I.1
Quinlan, D.J.2
Weitz, J.I.3
-
29
-
-
77957069112
-
New anticoagulants for the prevention of venous thromboembolism
-
Becattini C, Lignani A, Agnelli G. New anticoagulants for the prevention of venous thromboembolism. Drug Des Devel Ther 2010;4:49-60
-
(2010)
Drug des Devel Ther
, vol.4
, pp. 49-60
-
-
Becattini, C.1
Lignani, A.2
Agnelli, G.3
-
30
-
-
36348978071
-
The efficacy and safety of apixaban, an oral, direct factor Xa inhibitor, as thromboprophylaxis in patients following total knee replacement
-
DOI 10.1111/j.1538-7836.2007.02764.x
-
Lassen MR, Davidson BL, Gallus A, et al. The efficacy and safety of apixaban, an oral, direct factor Xa inhibitor, as thromboprophylaxis in patients following total knee replacement. J Thromb Haemost 2007;5:2368-75 (Pubitemid 350154345)
-
(2007)
Journal of Thrombosis and Haemostasis
, vol.5
, Issue.12
, pp. 2368-2375
-
-
Lassen, M.R.1
Davidson, B.L.2
Gallus, A.3
Pineo, G.4
Ansell, J.5
Deitchman, D.6
-
31
-
-
68249158084
-
Apixaban or enoxaparin for thromboprophylaxis after knee replacement
-
Lassen MR, Raskob GE, Gallus A, et al. Apixaban or enoxaparin for thromboprophylaxis after knee replacement. N Engl J Med 2009;361:594-604
-
(2009)
N Engl J Med
, vol.361
, pp. 594-604
-
-
Lassen, M.R.1
Raskob, G.E.2
Gallus, A.3
-
32
-
-
77649113258
-
Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): A randomised double-blind trial
-
for the ADVANCE-2 investigators
-
Lassen MR, Raskob GE, Gallus A, et al. for the ADVANCE-2 investigators. Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): a randomised double-blind trial. Lancet 2010; 375:807-15
-
(2010)
Lancet
, vol.375
, pp. 807-815
-
-
Lassen, M.R.1
Raskob, G.E.2
Gallus, A.3
-
33
-
-
23044505564
-
Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients
-
DOI 10.1111/j.1538-7836.2005.01204.x
-
Schulman S, Kearon C. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. J Thromb Haemost 2005;3:692-4 (Pubitemid 41647882)
-
(2005)
Journal of Thrombosis and Haemostasis
, vol.3
, Issue.4
, pp. 692-694
-
-
Schulman, S.1
Kearon, C.2
|