Terguride for pulmonary arterial hypertension

Expert Opinion on Therapeutic Targets

Volumn 15, Issue 11, 2011, Pages 1333-1335

  Antoniu, Sabina A ^a  

^a GRIGORE T POPA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

Pulmonary arterial hypertension; Serotonin; Terguride; Vascular remodeling

Indexed keywords

ANTIFIBROTIC AGENT; ANTIINFLAMMATORY AGENT; ANTIMITOTIC AGENT; COLLAGEN; COLLAGEN TYPE 2; DOPAMINE RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; SEROTONIN; TERGURIDE; TUMOR NECROSIS FACTOR ALPHA;

ARTERIAL OXYGEN SATURATION; ARTERIAL PRESSURE; ARTICLE; CARDIOPULMONARY HEMODYNAMICS; CELL PROLIFERATION; DRUG ACTIVITY; DRUG TOLERABILITY; ENDOTHELIAL DYSFUNCTION; HUMAN; LUNG ARTERY PRESSURE; NONHUMAN; PULMONARY HYPERTENSION; SMOOTH MUSCLE FIBER; VASOCONSTRICTION;

ANIMALS; DOPAMINE AGONISTS; FEMALE; HUMANS; HYPERTENSION, PULMONARY; LISURIDE; LUNG; MALE; SEROTONIN 5-HT2 RECEPTOR ANTAGONISTS;

EID: 80054691793     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2011.600692     Document Type: Article

References (4)

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2. Sun XZ, Li ZF, Liu Y, et al. Inhibition of cGMP phosphodiesterase 5 suppresses matrix metalloproteinase-2 production in pulmonary artery smooth muscles cells. Clin Exp Pharmacol Physiol 2010;15:362-7
3. Kim H, Yung GL, Marsh JJ, et al. Endothelin mediates pulmonary vascular remodelling in a canine model of chronic embolic pulmonary hypertension. Eur Respir J 2000;15:640-8 (Pubitemid 30196289)
4. Dumitrascu R, Kulcke C, Konigshoff M, et al. Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats. Eur Respir J 2011;37:1104-18