A fluoroquinolone-resistant acinetobacter baumannii without the quinolone resistance-determining region mutations

Journal of Antimicrobial Chemotherapy

Volumn 66, Issue 11, 2011, Pages 2668-2670

  Chopra, Sidharth ^a   Galande, Amit ^b  

^a SRI INTERNATIONAL   (United States)

^b Center for Advanced Drug Research (CADRE)   (United States)

Author keywords

A. baumannii; DNA gyrase; Plasmid mediated quinolone resistance; Topoisomerase

Indexed keywords

CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING) A; DNA TOPOISOMERASE (ATP HYDROLYSING) B; GATIFLOXACIN; MOXIFLOXACIN; NORFLOXACIN; POLYMYXIN B; PROTEIN PARC; PROTEIN PARE; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; BACTERIUM MUTANT; DNA SEQUENCE; LETTER; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE;

ACINETOBACTER BAUMANNII; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; DNA GYRASE; DNA TOPOISOMERASES, TYPE I; DRUG RESISTANCE, BACTERIAL; FLUOROQUINOLONES; MUTATION; PLASMIDS; SEQUENCE ANALYSIS, DNA;

EID: 80054686188     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkr364     Document Type: Letter

References (9)

1. Hujer KM, Hujer AM, Endimiani A et al. Rapid determination of quinolone resistance in Acinetobacter spp. J Clin Microbiol 2009; 47: 1436-42.
2. Chopra S, Torres-Ortiz M, Hokama L et al. Repurposing FDA-approved drugs to combat drug-resistant Acinetobacter baumannii. J Antimicrob Chemother 2010; 65: 2598-601.
3. Peleg AY, Seifert H, Paterson DL. Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev 2008; 21: 538-82.
4. Sato T, Yokota S, Uchida I et al. A fluoroquinolone-resistant Escherichia coli clinical isolate without quinolone resistance-determining region mutations found in Japan. Antimicrob Agents Chemother 2011; 55: 3964-5.
5. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: Seventeenth Informational Supplement M100-S17. CLSI, Wayne, PA, USA, 2007.
6. Smith MG, Gianoulis TA, Pukatzki S et al. New insights into Acinetobacter baumannii pathogenesis revealed by high-density pyrosequencing and transposon mutagenesis. Genes Dev 2007; 21: 601-14.
7. Yin XL, Hou TW, Xu SB et al. Detection of drug resistance-associated genes of multidrug-resistant Acinetobacter baumannii. Microb Drug Resist 2008; 14: 145-50.
8. Naqvi SM, Jenkins C, McHugh TD et al. Identification of the qnr family in Enterobacteriaceae in clinical practice. J Antimicrob Chemother 2009; 63: 830-2.
9. Touati A, Brasme L, Benallaoua S et al. First report of qnrB-producing Enterobacter cloacae and qnrA-producing Acinetobacter baumannii recovered from Algerian hospitals. Diagn Microbiol Infect Dis 2008; 60: 287-90.