Globular glial tauopathies (GGT) presenting with motor neuron disease or frontotemporal dementia: An emerging group of 4-repeat tauopathies

Acta Neuropathologica

Volumn 122, Issue 4, 2011, Pages 415-428

  Ahmed, Zeshan ^a,b   Doherty, Karen M ^b   Silveira Moriyama, Laura ^b   Bandopadhyay, Rina ^a,b   Lashley, Tammaryn ^a   Mamais, Adamantios ^a,b   Hondhamuni, Geshanthi ^b   Wray, Selina ^a   Newcombe, Jia ^a   O'Sullivan, Sean S ^b   Wroe, Stephen ^c   De Silva, Rohan ^b   Holton, Janice L ^a,b   Lees, Andrew J ^a,b   Revesz, Tamas ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

Astrocytes; Frontotemporal dementia; Motor neuron disease; Multiple system tauopathy with dementia; Oligodendroglia; Progressive supranuclear palsy; Tau

Indexed keywords

AGED; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; CASE REPORT; CONTROLLED STUDY; FEMALE; FRONTOTEMPORAL DEMENTIA; GLOBULAR OLIGODENDROGLIAL INCLUSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MOTOR NEURON DISEASE; NERVE DEGENERATION; NEUROPATHOLOGY; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; PROGRESSIVE SUPRANUCLEAR PALSY; PYRAMIDAL TRACT; SILVER STAINING; SYMPTOM; TAUOPATHY; WESTERN BLOTTING; WHITE MATTER;

AGED; DIAGNOSIS, DIFFERENTIAL; FATAL OUTCOME; FEMALE; FRONTOTEMPORAL DEMENTIA; HUMANS; MALE; MOTOR NEURON DISEASE; OLIGODENDROGLIA; TAUOPATHIES; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 80054682413     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0857-4     Document Type: Article

References (38)

1. M Baker I Litvan H Houlden, et al. 1999 Association of an extended haplotype in the tau gene with progressive supranuclear palsy Hum Mol Genet 8 711 715 10072441 10.1093/hmg/8.4.711 1:CAS:528:DyaK1MXitlGns7g%3D (Pubitemid 29139987)
2. Bergeron C, Morris HR, Rossor M (2003) Pick's Disease. In: Dickson DW (Ed) Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders, 1st Edn. ISN Neuropath Press, Basel, Pp 124-131
3. RW Berry B Quinn N Johnson EJ Cochran N Ghoshal LI Binder 2001 Pathological glial tau accumulations in neurodegenerative disease: review and case report Neurochem Int 39 469 479 11578782 10.1016/S0197-0186(01)00054-7 1:CAS:528:DC%2BD3MXntVylsr4%3D (Pubitemid 32907411)
4. EH Bigio AM Lipton SH Yen, et al. 2001 Frontal lobe dementia with novel tauopathy: sporadic multiple system tauopathy with dementia J Neuropathol Exp Neurol 60 328 341 11305868 1:STN:280:DC%2BD3M3hvVehsA%3D%3D (Pubitemid 32274048)
5. DW Dickson 1999 Neuropathologic differentiation of progressive supranuclear palsy and corticobasal degeneration J Neurol 246 Suppl 2 II6 II15 10525997 10.1007/BF03161076
6. Dickson DW, Litvan I (2003) Corticobasal degeneration. In: Dickson DW (ed) Neurodegeneration: the molecular pathology of dementia and movement disorders, 1st edn. ISN Neuropath Press, Basel, pp 115-123
7. DW Dickson Z Ahmed AA Algom Y Tsuboi KA Josephs 2010 Neuropathology of variants of progressive supranuclear palsy Curr Opin Neurol 23 394 400 20610990 10.1097/WCO.0b013e32833be924
8. DW Dickson R Rademakers ML Hutton 2007 Progressive supranuclear palsy: pathology and genetics Brain Pathol 17 74 82 17493041 10.1111/j.1750-3639.2007. 00054.x 1:CAS:528:DC%2BD2sXkvFShsr4%3D
9. MB Feany DW Dickson 1995 Widespread cytoskeletal pathology characterizes corticobasal degeneration Am J Pathol 146 1388 1396 7778678 1:STN:280: DyaK2M3pslGrug%3D%3D
10. I Ferrer I Hernandez M Boada, et al. 2003 Primary progressive aphasia as the initial manifestation of corticobasal degeneration and unusual tauopathies Acta Neuropathol 106 419 435 12955398 10.1007/s00401-003-0756-4 1:STN:280:DC%2BD3svntlOmuw%3D%3D (Pubitemid 37265846)
11. YJ Fu Y Nishihira S Kuroda, et al. 2010 Sporadic four-repeat tauopathy with frontotemporal lobar degeneration, Parkinsonism, and motor neuron disease: a distinct clinicopathological and biochemical disease entity Acta Neuropathol 120 21 32 20140439 10.1007/s00401-010-0649-2
12. F Gallyas 1971 Silver staining of Alzheimer's neurofibrillary changes by means of physical development Acta Morphol Acad Sci Hung 19 1 8 4107507 1:CAS:528:DyaE38Xit1OhtA%3D%3D
13. Ghetti B, Hutton ML, Wszolek ZK (2003) Frontotemporal dementia and parkinsonism linked to chromosome 17 associated with tau gene mutations (FTDP-17T). In: Dickson DW (ed) Neurodegeneration: the molecular pathology of dementia and movement disorders, 1st edn. ISN Neuropath Press, Basel, pp 86-102
14. JJ Hauw SE Daniel D Dickson, et al. 1994 Preliminary NINDS neuropathologic criteria for Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy) Neurology 44 2015 2019 7969952 1:STN:280: DyaK2M%2FlvF2rtg%3D%3D (Pubitemid 24349498)
15. JJ Hauw M Verny P Delaere P Cervera Y He C Duyckaerts 1990 Constant neurofibrillary changes in the neocortex in progressive supranuclear palsy. Basic differences with Alzheimer's disease and aging Neurosci Lett 119 182 186 1704110 10.1016/0304-3940(90)90829-X 1:STN:280:DyaK3M7isFKqsw%3D%3D (Pubitemid 20379252)
16. Hauw J, Agid Y (2003) Progressive supranuclear palsy (PSP) or Steele-Richardson-Olszewski disease. In: Dickson DW (ed) Neurodegeneration: the molecular pathology of dementia and movement disorders, 1st edn. ISN Neuropath Press, Basel, pp 103-114
17. K Ikeda H Akiyama C Haga H Kondo K Arima T Oda 1994 Argyrophilic thread-like structure in corticobasal degeneration and supranuclear palsy Neurosci Lett 174 157 159 7526285 10.1016/0304-3940(94)90010-8 1:STN:280:DyaK2M%2FmtVahsQ%3D%3D (Pubitemid 24199487)
18. KA Josephs O Katsuse DA Beccano-Kelly, et al. 2006 Atypical progressive supranuclear palsy with corticospinal tract degeneration J Neuropathol Exp Neurol 65 396 405 16691120 10.1097/01.jnen.0000218446.38158.61 (Pubitemid 44264836)
19. T Komori 1999 Tau-positive glial inclusions in progressive supranuclear palsy, corticobasal degeneration and Pick's disease Brain Pathol 9 663 679 10517506 10.1111/j.1750-3639.1999.tb00549.x 1:STN:280:DyaK1MvksFSqtg%3D%3D (Pubitemid 29470960)
20. GG Kovacs K Majtenyi S Spina, et al. 2008 White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration J Neuropathol Exp Neurol 67 963 975 18800011 10.1097/NEN.0b013e318187a80f
21. Lantos PL, Quinn N (2003) Multiple system atrophy. In: Dickson DW (ed) Neurodegeneration: the molecular pathology of dementia and movement disorders, 1st edn. ISN Neuropath Press, Basel, pp 203-214
22. Lashley T, Rohrer J, Bandopadhyay R et al (2011) A comparative clinical, pathological and biochemical study of FUS proteinopathies. Brain (in press)
23. I Litvan JJ Hauw JJ Bartko, et al. 1996 Validity and reliability of the preliminary NINDS neuropathologic criteria for progressive supranuclear palsy and related disorders J Neuropathol Exp Neurol 55 97 105 8558176 10.1097/00005072-199601000-00010 1:STN:280:DyaK287js1Wlsw%3D%3D (Pubitemid 26013790)
24. IR Mackenzie 2007 The neuropathology of FTD associated With ALS Alzheimer Dis Assoc Disord 21 S44 S49 18090423 10.1097/WAD.0b013e31815c3486 (Pubitemid 350307444)
25. IR Mackenzie M Neumann EH Bigio, et al. 2010 Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update Acta Neuropathol 119 1 4 19924424 10.1007/s00401-009-0612-2
26. IR Mackenzie M Neumann EH Bigio, et al. 2009 Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations Acta Neuropathol 117 15 18 19015862 10.1007/s00401-008-0460-5
27. S Ohara J Tsuyuzaki T Oide, et al. 2002 A clinical and neuropathological study of an unusual case of sporadic tauopathy. A variant of corticobasal degeneration? Neurosci Lett 330 84 88 12213640 10.1016/S0304-3940(02)00616-X 1:CAS:528:DC%2BD38Xms1ygs70%3D (Pubitemid 35245775)
28. K Oyanagi M Wada 1999 Neuropathology of parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam: an update J Neurol 246 Suppl 2 II19 II27 10525999 10.1007/BF03161078
29. P Poorkaj TD Bird E Wijsman, et al. 1998 Tau is a candidate gene for chromosome 17 frontotemporal dementia Ann Neurol 43 815 825 9629852 10.1002/ana.410430617 1:CAS:528:DyaK1cXktVSjsL8%3D (Pubitemid 28280226)
30. JM Powers NP Byrne M Ito, et al. 2003 A novel leukoencephalopathy associated with tau deposits primarily in white matter glia Acta Neuropathol 106 181 187 12783250 10.1007/s00401-003-0719-9 1:STN:280:DC%2BD3szgs1Cktg%3D%3D (Pubitemid 36869254)
31. CE Pringle AJ Hudson DG Munoz JA Kiernan WF Brown GC Ebers 1992 Primary lateral sclerosis. Clinical features, neuropathology and diagnostic criteria Brain 115 Pt 2 495 520 1606479 10.1093/brain/115.2.495
32. K Sakai YS Piao K Kikugawa, et al. 2006 Corticobasal degeneration with focal, massive tau accumulation in the subcortical white matter astrocytes Acta Neuropathol 112 341 348 16804710 10.1007/s00401-006-0093-5 (Pubitemid 44275889)
33. JC Steele JC Richardson J Olszewski 1964 Progressive supranuclear palsy. A heterogeneous degeneration involving the brain stem, basal ganglia and cerebellum with vertical gaze and pseudobulbar palsy, nuchal dystonia and dementia Arch Neurol 10 333 359 14107684 1:STN:280:DyaF2c%2FmsFektA%3D%3D
34. M Swash J Desai VP Misra 1999 What is primary lateral sclerosis? J Neurol Sci 170 5 10 10540029 10.1016/S0022-510X(99)00184-7 1:STN:280: DC%2BD3c%2FgvFOhsw%3D%3D (Pubitemid 29502528)
35. T Takahashi N Amano T Hanihara, et al. 1996 Corticobasal degeneration: widespread argentophilic threads and glia in addition to neurofibrillary tangles. Similarities of cytoskeletal abnormalities in corticobasal degeneration and progressive supranuclear palsy J Neurol Sci 138 66 77 8791241 10.1016/0022-510X(95)00347-5 1:STN:280:DyaK28zotlektQ%3D%3D (Pubitemid 26194277)
36. CF Tan YS Piao A Kakita, et al. 2005 Frontotemporal dementia with co-occurrence of astrocytic plaques and tufted astrocytes, and severe degeneration of the cerebral white matter: a variant of corticobasal degeneration? Acta Neuropathol 109 329 338 15841415 10.1007/s00401-004-0933-0 (Pubitemid 41166603)
37. DR Williams AJ Lees 2009 Progressive supranuclear palsy: clinicopathological concepts and diagnostic challenges Lancet Neurol 8 270 279 19233037 10.1016/S1474-4422(09)70042-0
38. S Wray M Saxton BH Anderton DP Hanger 2008 Direct analysis of tau from PSP brain identifies new phosphorylation sites and a major fragment of N-terminally cleaved tau containing four microtubule-binding repeats J Neurochem 105 2343 2352 18315566 10.1111/j.1471-4159.2008.05321.x 1:CAS:528: DC%2BD1cXnvVWiur8%3D (Pubitemid 351782262)