Spiro indane-1,3-dione pyrrolizidine compounds synthesized by 1,3-dipolar cyclo-addition reaction

Heterocyclic Communications

Volumn 17, Issue 3-4, 2011, Pages 161-163

  Chen, Gang ^a   Wu, Ya ^a   Gu, Xuefan ^a  

^a XI'AN SHIYOU UNIVERSITY   (China)

Author keywords

1,3 dipolar cycloaddition; Regioselectivity; Spiro compounds

Indexed keywords

EID: 80054123876     PISSN: 07930283     EISSN: None     Source Type: Journal    
DOI: 10.1515/HC.2011.023     Document Type: Article

References (8)

1. Amal Raj, A.; Raghunathan R. A novel entry into a new class of spiroheterocyclic framework: regioselective synthesis of dispiro[oxindole- cyclohexanone]pyrrolidines and dispiro[oxiindole-hexahydroindazole]pyrrolidines. Tetrahedron 2001 , 57 , 10293-10298. (Pubitemid 34008628)
2. Amal Raj, A.; Raghunathan, R.; Sridevikumari, M. R.; Raman, N. Synthesis, antimicrobial and antifungal activity of a new class of spiro pyrrolidines. Bioorg. Med. Chem. 2003 , 11 , 407-419. (Pubitemid 36051031)
3. Chen, G.; He, H. P.; Ding, J.; Hao, X. J. Synthesis and antitumor activity evaluation of regioselective spiro [pyrrolidine-2,3 ? - oxindole] compounds. Heterocyl. Commun. 2009 , 15 , 355-360.
4. Fokas, D.; Ryan, W. J.; Casebier D. S.; Coffen, D. L. Solution phase synthesis of a spiro [pyrrolidine-2,3 ? -oxindole] library via a three component 1,3-dipolar cycloaddition reaction. Tetrahedron Lett . 1998 , 39 , 2235-2238. (Pubitemid 28167929)
5. Huisgen, R. On the mechanism of 1,3-dipolar cycloadditions. A reply. J. Org. Chem. 1968 , 33 , 2291-2297.
6. 3 . Z Krist-New Cryst. St. 2010 , 225 , 355-356.
7. Okino, T.; Hoashi, Y.; Furukawa, T.; Xu, X.; Takemoto, Y. Synthesis of ( - )-Tetracycline. J. Am. Chem. Soc. 2005 , 127 , 119-125.
8. Rehn, S.; Bergman, J.; Stensland, B. The three-component reaction between isatin, á -amino acids, and dipolarophiles. Eur. J. Org. Chem. 2004 , 2004, 413-418.