메뉴 건너뛰기




Volumn 17, Issue 20, 2011, Pages 6500-6509

Significant biological role of Sp1 transactivation in multiple myeloma

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; FIREFLY LUCIFERASE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TERAMEPROCOL; TRANSCRIPTION FACTOR SP1;

EID: 80054115013     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-11-1036     Document Type: Article
Times cited : (51)

References (50)
  • 1
    • 0032866999 scopus 로고    scopus 로고
    • The Sp-family of transcription factors
    • DOI 10.1016/S0378-1119(99)00357-1, PII S0378111999003571
    • Suske G. The Sp-family of transcription factors. Gene 1999;238:291-300. (Pubitemid 29446168)
    • (1999) Gene , vol.238 , Issue.2 , pp. 291-300
    • Suske, G.1
  • 3
    • 0033952803 scopus 로고    scopus 로고
    • Regulation of interaction of the acetyltransferase region of p300 and the DNA-binding domain of Sp1 on and through DNA binding
    • Suzuki T, Kimura A, Nagai R, Horikoshi M. Regulation of interaction of the acetyltransferase region of p300 and the DNA-binding domain of Sp1 on and through DNA binding. Genes Cells 2000;5:29-41. (Pubitemid 30095679)
    • (2000) Genes to Cells , vol.5 , Issue.1 , pp. 29-41
    • Suzuki, T.1    Kimura, A.2    Nagai, R.3    Horikoshi, M.4
  • 4
    • 0038519756 scopus 로고    scopus 로고
    • Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor beta type II receptor expression in human pancreatic cancer cells
    • Zhao S, Venkatasubbarao K, Li S, Freeman JW. Requirement of a specific Sp1 site for histone deacetylase-mediated repression of transforming growth factor beta type II receptor expression in human pancreatic cancer cells. Cancer Res 2003;63:2624-30. (Pubitemid 36605205)
    • (2003) Cancer Research , vol.63 , Issue.10 , pp. 2624-2630
    • Zhao, S.1    Venkatasubbarao, K.2    Li, S.3    Freeman, J.W.4
  • 5
    • 0034929708 scopus 로고    scopus 로고
    • Sp1 and Kruppel-like factor family of transcription factors in cell growth regulation and cancer
    • DOI 10.1002/jcp.1111
    • Black AR, Black JD, Azizkhan-Clifford J. Sp1 and Kruppel-like factor family of transcription factors in cell growth regulation and cancer. J Cell Physiol 2001;188:143-60. (Pubitemid 32622905)
    • (2001) Journal of Cellular Physiology , vol.188 , Issue.2 , pp. 143-160
    • Black, A.R.1    Black, J.D.2    Azizkhan-Clifford, J.3
  • 6
    • 0037047327 scopus 로고    scopus 로고
    • Small inhibitory RNA duplexes for Sp1 mRNA block basal and estrogeninduced gene expression and cell cycle progression in MCF-7 breast cancer cells
    • Abdelrahim M, Samudio I, Smith R III, Burghardt R, Safe S. Small inhibitory RNA duplexes for Sp1 mRNA block basal and estrogeninduced gene expression and cell cycle progression in MCF-7 breast cancer cells. J Biol Chem 2002;277:28815-22.
    • (2002) J Biol Chem , vol.277 , pp. 28815-28822
    • Abdelrahim, M.1    Samudio, I.2    Smith III, R.3    Burghardt, R.4    Safe, S.5
  • 7
    • 23044452436 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors decrease vascular endothelial growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 proteins
    • DOI 10.1124/mol.105.011825
    • Abdelrahim M, Safe S. Cyclooxygenase-2 inhibitors decrease vascular endothelial growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 proteins. Mol Pharmacol 2005;68:317-29. (Pubitemid 41058295)
    • (2005) Molecular Pharmacology , vol.68 , Issue.2 , pp. 317-329
    • Abdelrahim, M.1    Safe, S.2
  • 8
    • 33751277288 scopus 로고    scopus 로고
    • Loss of Kruppel-like factor 4 expression contributes to Sp1 overexpression and human gastric cancer development and progression
    • DOI 10.1158/1078-0432.CCR-06-1034
    • Kanai M, Wei D, Li Q, Jia Z, Ajani J, Le X, et al. Loss of Kruppel-like factor 4 expression contributes to Sp1 overexpression and human gastric cancer development and progression. Clin Cancer Res 2006; 12:6395-402. (Pubitemid 44799710)
    • (2006) Clinical Cancer Research , vol.12 , Issue.21 , pp. 6395-6402
    • Kanai, M.1    Wei, D.2    Li, Q.3    Jia, Z.4    Ajani, J.5    Le, X.6    Yao, J.7    Xie, K.8
  • 9
    • 0035872399 scopus 로고    scopus 로고
    • Constitutive Sp1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma
    • Shi Q, Le X, Abbruzzese JL, Peng Z, Qian CN, Tang H, et al. Constitutive Sp1 activity is essential for differential constitutive expression of vascular endothelial growth factor in human pancreatic adenocarcinoma. Cancer Res 2001;61:4143-54. (Pubitemid 32720983)
    • (2001) Cancer Research , vol.61 , Issue.10 , pp. 4143-4154
    • Shi, Q.1    Le, X.2    Abbruzzese, J.L.3    Peng, Z.4    Qian, C.-N.5    Tang, H.6    Xiong, Q.7    Wang, B.8    Li, X.-C.9    Xie, K.10
  • 10
    • 34248160592 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells
    • DOI 10.1158/0008-5472.CAN-06-3831
    • Abdelrahim M, Baker CH, Abbruzzese JL, Sheikh-Hamad D, Liu S, Cho SD, et al. Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells. Cancer Res 2007;67:3286-94. (Pubitemid 46724867)
    • (2007) Cancer Research , vol.67 , Issue.7 , pp. 3286-3294
    • Abdelrahim, M.1    Baker, C.H.2    Abbruzzese, J.L.3    Sheikh-Hamad, D.4    Liu, S.5    Sung, D.C.6    Yoon, K.7    Safe, S.8
  • 11
    • 33847736187 scopus 로고    scopus 로고
    • Sp1 is required for transforming growth factor-beta-induced mesenchymal transition and migration in pancreatic cancer cells
    • DOI 10.1158/0008-5472.CAN-06-1670
    • Jungert K, Buck A, von Wichert G, Adler G, Konig A, Buchholz M, et al. Sp1 is required for transforming growth factor-beta-induced mesenchymal transition and migration in pancreatic cancer cells. Cancer Res 2007;67:1563-70. (Pubitemid 46383380)
    • (2007) Cancer Research , vol.67 , Issue.4 , pp. 1563-1570
    • Jungert, K.1    Buck, A.2    Von Wichert, G.3    Adler, G.4    Konig, A.5    Buchholz, M.6    Gress, T.M.7    Ellenrieder, V.8
  • 13
    • 3042752956 scopus 로고    scopus 로고
    • Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: A role in NIS expression regulation?
    • Chiefari E, Brunetti A, Arturi F, Bidart JM, Russo D, Schlumberger M, et al. Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation? BMC Cancer 2002;2:35.
    • (2002) BMC Cancer , vol.2 , pp. 35
    • Chiefari, E.1    Brunetti, A.2    Arturi, F.3    Bidart, J.M.4    Russo, D.5    Schlumberger, M.6
  • 15
    • 37049006332 scopus 로고    scopus 로고
    • Therapeutic inhibition of Sp1 expression in growing tumors by mithramycin A correlates directly with potent antiangiogenic effects on human pancreatic cancer
    • DOI 10.1002/cncr.23092
    • Yuan P, Wang L, Wei D, Zhang J, Jia Z, Li Q, et al. Therapeutic inhibition of Sp1 expression in growing tumors by mithramycin a correlates directly with potent antiangiogenic effects on human pancreatic cancer. Cancer 2007;110:2682-90. (Pubitemid 350250337)
    • (2007) Cancer , vol.110 , Issue.12 , pp. 2682-2690
    • Yuan, P.1    Wang, L.2    Wei, D.3    Zhang, J.4    Jia, Z.5    Li, Q.6    Le, X.7    Wang, H.8    Yao, J.9    Xie, K.10
  • 16
    • 0033709613 scopus 로고    scopus 로고
    • Sp1 decoy transfected to carcinoma cells suppresses the expression of vascular endothelial growth factor, transforming growth factor beta1, and tissue factor and also cell growth and invasion activities
    • Ishibashi H, Nakagawa K, Onimaru M, Castellanous EJ, Kaneda Y, Nakashima Y, et al. Sp1 decoy transfected to carcinoma cells suppresses the expression of vascular endothelial growth factor, transforming growth factor beta1, and tissue factor and also cell growth and invasion activities. Cancer Res 2000;60:6531-6.
    • (2000) Cancer Res , vol.60 , pp. 6531-6536
    • Ishibashi, H.1    Nakagawa, K.2    Onimaru, M.3    Castellanous, E.J.4    Kaneda, Y.5    Nakashima, Y.6
  • 17
    • 13444267281 scopus 로고    scopus 로고
    • Down-regulation of overexpression Sp1 protein in human fibrosarcoma cell lines inhibits tumor formation
    • Lou Z, O'Reilly S, Liang H, Maher VM, Sleight SD, McCormick JJ. Down-regulation of overexpressed sp1 protein in human fibrosarcoma cell lines inhibits tumor formation. Cancer Res 2005;65: 1007-17. (Pubitemid 40216463)
    • (2005) Cancer Research , vol.65 , Issue.3 , pp. 1007-1017
    • Lou, Z.1    O'Reilly, S.2    Liang, H.3    Maher, V.M.4    Sleight, S.D.5    McCormick, J.J.6
  • 18
    • 18144408014 scopus 로고    scopus 로고
    • Induction of endoplasmic reticulum-induced stress genes in Panc-1 pancreatic cancer cells is dependent on Sp proteins
    • DOI 10.1074/jbc.C500030200
    • Abdelrahim M, Liu S, Safe S. Induction of endoplasmic reticuluminduced stress genes in Panc-1 pancreatic cancer cells is dependent on Sp proteins. J Biol Chem 2005;280:16508-13. (Pubitemid 40616782)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.16 , pp. 16508-16513
    • Abdelrahim, M.1    Liu, S.2    Safe, S.3
  • 19
    • 41649111290 scopus 로고    scopus 로고
    • Phosphorylation by c-Jun NH2-terminal kinase 1 regulates the stability of transcription factor Sp1 during mitosis
    • Chuang JY, Wang YT, Yeh SH, Liu YW, Chang WC, Hung JJ. Phosphorylation by c-Jun NH2-terminal kinase 1 regulates the stability of transcription factor Sp1 during mitosis. Mol Biol Cell 2008;19: 1139-51.
    • (2008) Mol Biol Cell , vol.19 , pp. 1139-1151
    • Chuang, J.Y.1    Wang, Y.T.2    Yeh, S.H.3    Liu, Y.W.4    Chang, W.C.5    Hung, J.J.6
  • 20
    • 0035001054 scopus 로고    scopus 로고
    • Blocking Sp1 transcription factor broadly inhibits extracellular matrix gene expression in vitro and in vivo: Implications for the treatment of tissue fibrosis
    • DOI 10.1046/j.1523-1747.2001.01326.x
    • Verrecchia F, Rossert J, Mauviel A. Blocking sp1 transcription factor broadly inhibits extracellular matrix gene expression in vitro and in vivo: implications for the treatment of tissue fibrosis. J Invest Dermatol 2001;116:755-63. (Pubitemid 32467656)
    • (2001) Journal of Investigative Dermatology , vol.116 , Issue.5 , pp. 755-763
    • Verrecchia, F.1    Rossert, J.2    Mauviel, A.3
  • 21
    • 3042753807 scopus 로고    scopus 로고
    • MAPK and JNK transduction pathways can phosphorylate Sp1 to activate the uPA minimal promoter element and endogenous gene transcription
    • DOI 10.1182/blood-2003-08-2661
    • Benasciutti E, Pages G, Kenzior O, Folk W, Blasi F, Crippa MP. MAPK and JNK transduction pathways can phosphorylate Sp1 to activate the uPA minimal promoter element and endogenous gene transcription. Blood 2004;104:256-62. (Pubitemid 38879866)
    • (2004) Blood , vol.104 , Issue.1 , pp. 256-262
    • Benasciutti, E.1    Pages, G.2    Kenzior, O.3    Folk, W.4    Blasi, F.5    Crippa, M.P.6
  • 22
    • 34249063875 scopus 로고    scopus 로고
    • Membrane-type 1 matrix metalloproteinase is regulated by Sp1 through the differential activation of AKT, JNK, and ERK pathways in human prostate tumor cells
    • DOI 10.1593/neo.07193
    • Sroka IC, Nagle RB, Bowden GT. Membrane-type 1 matrix metalloproteinase is regulated by sp1 through the differential activation of AKT, JNK, and ERK pathways in human prostate tumor cells. Neoplasia 2007;9:406-17. (Pubitemid 46799984)
    • (2007) Neoplasia , vol.9 , Issue.5 , pp. 406-417
    • Sroka, I.C.1    Nagle, R.B.2    Bowden, G.T.3
  • 23
    • 66349099956 scopus 로고    scopus 로고
    • Sp1 phosphorylation and its regulation of gene transcription
    • Tan NY, Khachigian LM. Sp1 phosphorylation and its regulation of gene transcription. Mol Cell Biol 2009;29:2483-8.
    • (2009) Mol Cell Biol , vol.29 , pp. 2483-2488
    • Tan, N.Y.1    Khachigian, L.M.2
  • 24
    • 15744393419 scopus 로고    scopus 로고
    • Sp1: Regulation of gene expression by phosphorylation
    • DOI 10.1016/j.gene.2005.01.013
    • Chu S, Ferro TJ. Sp1: regulation of gene expression by phosphorylation. Gene 2005;348:1-11. (Pubitemid 40410011)
    • (2005) Gene , vol.348 , Issue.1-2 SUPPL. , pp. 1-11
    • Chu, S.1    Ferro, T.J.2
  • 25
    • 45449112944 scopus 로고    scopus 로고
    • Transcriptional regulation of autocrine IL-6 expression in MM cells
    • Gerlo S, Haegeman G, Vanden Berghe W. Transcriptional regulation of autocrine IL-6 expression in MM cells. Cell Signal 2008;20:1489-96.
    • (2008) Cell Signal , vol.20 , pp. 1489-1496
    • Gerlo, S.1    Haegeman, G.2    Vanden Berghe, W.3
  • 27
    • 0033082526 scopus 로고    scopus 로고
    • Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
    • Takakura M, Kyo S, Kanaya T, Hirano H, Takeda J, Yutsudo M, et al. Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res 1999;59:551-7. (Pubitemid 29076049)
    • (1999) Cancer Research , vol.59 , Issue.3 , pp. 551-557
    • Takakura, M.1    Kyo, S.2    Kanaya, T.3    Hirano, H.4    Takeda, J.5    Yutsudo, M.6    Inoue, M.7
  • 30
    • 34547670300 scopus 로고    scopus 로고
    • The anticancer activity of the transcription inhibitor terameprocol (meso-tetra-O-methyl nordihydroguaiaretic acid) formulated for systemic administration
    • DOI 10.1097/CAD.0b013e32813148e0, PII 0000181320070900000009
    • Lopez RA, Goodman AB, Rhodes M, Blomberg JA, Heller J. The anticancer activity of the transcription inhibitor terameprocol (mesotetra- O-methyl nordihydroguaiaretic acid) formulated for systemic administration. Anticancer Drugs 2007;18:933-9. (Pubitemid 47220712)
    • (2007) Anti-Cancer Drugs , vol.18 , Issue.8 , pp. 933-939
    • Lopez, R.A.1    Goodman, A.B.2    Rhodes, M.3    Blomberg, J.A.L.4    Heller, J.5
  • 31
    • 77952559263 scopus 로고    scopus 로고
    • A proto-oncogene BCL6 is up-regulated in the bone marrow microenvironment in MM cells
    • Hideshima T, Mitsiades C, Ikeda H, Chauhan D, Raje N, Gorgun G, et al. A proto-oncogene BCL6 is up-regulated in the bone marrow microenvironment in MM cells. Blood 2010;115: 3772-5.
    • (2010) Blood , vol.115 , pp. 3772-3775
    • Hideshima, T.1    Mitsiades, C.2    Ikeda, H.3    Chauhan, D.4    Raje, N.5    Gorgun, G.6
  • 33
    • 15644363078 scopus 로고    scopus 로고
    • Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of Tat-regulated HIV transactivation
    • DOI 10.1021/jm970819w
    • Hwu JR, Tseng WN, Gnabre J, Giza P, Huang RC. Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation. J Med Chem 1998;41:2994-3000. (Pubitemid 28359934)
    • (1998) Journal of Medicinal Chemistry , vol.41 , Issue.16 , pp. 2994-3000
    • Hwu, J.R.1    Tseng, W.N.2    Gnabre, J.3    Giza, P.4    Huang, R.C.C.5
  • 34
    • 0032581467 scopus 로고    scopus 로고
    • Antiviral activities of methylated nordihydroguaiaretic acids. 2. Targeting herpes simplex virus replication by the mutation insensitive transcription inhibitor Tetra-O-methyl-NDGA
    • DOI 10.1021/jm980182w
    • Chen H, Teng L, Li JN, Park R, Mold DE, Gnabre J, et al. Antiviral activities of methylated nordihydroguaiaretic acids. 2. Targeting herpes simplex virus replication by the mutation insensitive transcription inhibitor tetra-O-methyl-NDGA. J Med Chem 1998;41: 3001-7. (Pubitemid 28359935)
    • (1998) Journal of Medicinal Chemistry , vol.41 , Issue.16 , pp. 3001-3007
    • Chen, H.1    Teng, L.2    Li, J.-N.3    Park, R.4    Mold, D.E.5    Gnabre, J.6    Hwu, J.R.7    Tseng, W.N.8    Huang, R.C.C.9
  • 35
    • 0028820788 scopus 로고
    • Inhibition of human immunodeficiency virus type 1 transcription and replication by DNA sequence-selective plant lignans
    • Gnabre JN, Brady JN, Clanton DJ, Ito Y, Dittmer J, Bates RB, et al. Inhibition of human immunodeficiency virus type 1 transcription and replication by DNA sequence-selective plant lignans. Proc Natl Acad Sci U S A 1995;92:11239-43.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 11239-11243
    • Gnabre, J.N.1    Brady, J.N.2    Clanton, D.J.3    Ito, Y.4    Dittmer, J.5    Bates, R.B.6
  • 36
    • 19444363382 scopus 로고    scopus 로고
    • Influence of ions, hydration, and the transcriptional inhibitor P4N on the conformations of the Sp1 binding site
    • DOI 10.1016/j.jmb.2005.04.001, PII S0022283605003888
    • Dohm JA, Hsu MH, Hwu JR, Huang RC, Moudrianakis EN, Lattman EE, et al. Influence of ions, hydration, and the transcriptional inhibitor P4N on the conformations of the Sp1 binding site. J Mol Biol 2005; 349:731-44. (Pubitemid 40725951)
    • (2005) Journal of Molecular Biology , vol.349 , Issue.4 , pp. 731-744
    • Dohm, J.A.1    Hsu, M.-H.2    Hwu, J.-R.3    Huang, R.C.C.4    Moudrianakis, E.N.5    Lattman, E.E.6    Gittis, A.G.7
  • 37
    • 0033168929 scopus 로고    scopus 로고
    • The cancer antiapoptosis mouse survivin gene: Characterization of locus and transcriptional requirements of basal and cell cycle-dependent expression
    • Li F, Altieri DC. The cancer antiapoptosis mouse survivin gene: characterization of locus and transcriptional requirements of basal and cell cycle-dependent expression. Cancer Res 1999;59: 3143-51. (Pubitemid 29316014)
    • (1999) Cancer Research , vol.59 , Issue.13 , pp. 3143-3151
    • Li, F.1    Altieri, D.C.2
  • 38
    • 40049106474 scopus 로고    scopus 로고
    • Terameprocol, a novel site-specific transcription inhibitor with anticancer activity
    • Smolewski P. Terameprocol, a novel site-specific transcription inhibitor with anticancer activity. IDrugs 2008;11:204-14. (Pubitemid 351323375)
    • (2008) IDrugs , vol.11 , Issue.3 , pp. 204-214
    • Smolewski, P.1
  • 39
    • 34748812540 scopus 로고    scopus 로고
    • Selenium inhibition of survivin expression by preventing Sp1 binding to its promoter
    • DOI 10.1158/1535-7163.MCT-07-0172
    • Chun JY, Hu Y, Pinder E, Wu J, Li F, Gao AC. Selenium inhibition of survivin expression by preventing Sp1 binding to its promoter. Mol Cancer Ther 2007;6:2572-80. (Pubitemid 47480423)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.9 , pp. 2572-2580
    • Jae, Y.C.1    Hu, Y.2    Pinder, E.3    Wu, J.4    Li, F.5    Gao, A.C.6
  • 40
    • 57249098390 scopus 로고    scopus 로고
    • Functional significance of a putative sp1 transcription factor binding site in the survivin gene promoter
    • Mityaev MV, Kopantzev EP, Buzdin AA, Vinogradova TV, Sverdlov ED. Functional significance of a putative sp1 transcription factor binding site in the survivin gene promoter. Biochemistry 2008;73: 1183-91.
    • (2008) Biochemistry , vol.73 , pp. 1183-1191
    • Mityaev, M.V.1    Kopantzev, E.P.2    Buzdin, A.A.3    Vinogradova, T.V.4    Sverdlov, E.D.5
  • 42
    • 33744925726 scopus 로고    scopus 로고
    • The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter
    • DOI 10.1038/sj.onc.1209363
    • Li Y, Xie M, Yang J, Yang D, Deng R, Wan Y, et al. The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter. Oncogene 2006;25:3296-306. (Pubitemid 43846314)
    • (2006) Oncogene , vol.25 , Issue.23 , pp. 3296-3306
    • Li, Y.1    Xie, M.2    Yang, J.3    Yang, D.4    Deng, R.5    Wan, Y.6    Yan, B.7
  • 43
    • 66449110010 scopus 로고    scopus 로고
    • Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression
    • Konduri S, Colon J, Baker CH, Safe S, Abbruzzese JL, Abudayyeh A, et al. Tolfenamic acid enhances pancreatic cancer cell and tumor response to radiation therapy by inhibiting survivin protein expression. Mol Cancer Ther 2009;8:533-42.
    • (2009) Mol Cancer Ther , vol.8 , pp. 533-542
    • Konduri, S.1    Colon, J.2    Baker, C.H.3    Safe, S.4    Abbruzzese, J.L.5    Abudayyeh, A.6
  • 44
    • 33745226490 scopus 로고    scopus 로고
    • Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation
    • DOI 10.1093/jnci/djj232
    • Abdelrahim M, Baker CH, Abbruzzese JL, Safe S. Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation. J Natl Cancer Inst 2006;98:855-68. (Pubitemid 43923442)
    • (2006) Journal of the National Cancer Institute , vol.98 , Issue.12 , pp. 855-868
    • Abdelrahim, M.1    Baker, C.H.2    Abbruzzese, J.L.3    Safe, S.4
  • 46
  • 48
    • 77951554549 scopus 로고    scopus 로고
    • Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts
    • Goffin L, Seguin-Estevez Q, Alvarez M, Reith W, Chizzolini C. Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts. Arthritis Res Ther 2010;12:R73.
    • (2010) Arthritis Res Ther , vol.12
    • Goffin, L.1    Seguin-Estevez, Q.2    Alvarez, M.3    Reith, W.4    Chizzolini, C.5
  • 49
    • 77955871803 scopus 로고    scopus 로고
    • Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in MM
    • Kikuchi J, Wada T, Shimizu R, Izumi T, Akutsu M, Mitsunaga K, et al. Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in MM. Blood 2010;116;406-17.
    • (2010) Blood , vol.116 , pp. 406-417
    • Kikuchi, J.1    Wada, T.2    Shimizu, R.3    Izumi, T.4    Akutsu, M.5    Mitsunaga, K.6
  • 50
    • 70349739288 scopus 로고    scopus 로고
    • Pomalidomide and lenalidomide induce p21 WAF-1 expression in both lymphoma and MM through a LSD1- Mediated epigenetic mechanism
    • Escoubet-Lozach L, Lin IL, Jensen-Pergakes K, Brady HA, Gandhi AK, Schafer PH, et al. Pomalidomide and lenalidomide induce p21 WAF-1 expression in both lymphoma and MM through a LSD1- mediated epigenetic mechanism. Cancer Res 2009;69:7347-56.
    • (2009) Cancer Res , vol.69 , pp. 7347-7356
    • Escoubet-Lozach, L.1    Lin, I.L.2    Jensen-Pergakes, K.3    Brady, H.A.4    Gandhi, A.K.5    Schafer, P.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.