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Volumn 23, Issue 6, 2011, Pages 587-593

CD30-targeted antibody therapy

Author keywords

anaplastic large cell lymphoma; antibody drug conjugate; auristatin; Hodgkin's lymphoma; SGN 35

Indexed keywords

AFM 13; ANTIBODY; ANTIBODY CONJUGATE; BRENTUXIMAB VEDOTIN; CD30 ANTIBODY; CD30 ANTIGEN; CD30 LIGAND; HISTONE DEACETYLASE INHIBITOR; IRATUMUMAB; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD30; MONOCLONAL ANTIBODY KI 4 I 131; RADIOIMMUNOCONJUGATE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

EID: 80054111050     PISSN: 10408746     EISSN: 1531703X     Source Type: Journal    
DOI: 10.1097/CCO.0b013e32834bb8a7     Document Type: Review
Times cited : (57)

References (52)
  • 1
    • 0019981972 scopus 로고
    • Production of a monoclonal antibody specific for Hodgkin and Sternberg-Reed cells of Hodgkin's disease and a subset of normal lymphoid cells
    • DOI 10.1038/299065a0
    • Schwab U, Stein H, Gerdes J, et al. Production of a monoclonal antibody specific for Hodgkin and Sternberg-Reed cells of Hodgkin's disease and a subset of normal lymphoid cells. Nature 1982; 299:65-67. (Pubitemid 12049770)
    • (1982) Nature , vol.299 , Issue.5878 , pp. 65-67
    • Schwab, U.1    Stein, H.2    Gerdes, J.3
  • 2
    • 0026601968 scopus 로고
    • Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease
    • Durkop H, Latza U, Hummel M, et al. Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease. Cell 1992; 68:421-427.
    • (1992) Cell , vol.68 , pp. 421-427
    • Durkop, H.1    Latza, U.2    Hummel, M.3
  • 3
    • 0026595307 scopus 로고
    • Assignment of the human CD30 (Ki-1) gene to 1p36
    • Fonatsch C, Latza U, Durkop H, et al. Assignment of the human CD30 (Ki-1) gene to 1p36. Genomics 1992; 14:825-826.
    • (1992) Genomics , vol.14 , pp. 825-826
    • Fonatsch, C.1    Latza, U.2    Durkop, H.3
  • 5
    • 1542787698 scopus 로고    scopus 로고
    • Clinicopathologic and molecular features of Hodgkin's lymphoma
    • Younes A, Carbone A. Clinicopathologic and molecular features of Hodgkin's lymphoma. Cancer Biol Ther 2003; 2:500-507.
    • (2003) Cancer Biol Ther , vol.2 , pp. 500-507
    • Younes, A.1    Carbone, A.2
  • 6
    • 0032751560 scopus 로고    scopus 로고
    • CD30/CD30 ligand and CD40/CD40 ligand in malignant lymphoid disorders
    • Younes A, Carbone A. CD30/CD30 ligand and CD40/CD40 ligand in malignant lymphoid disorders. Int J Biol Markers 1999; 14:135-143. (Pubitemid 29495742)
    • (1999) International Journal of Biological Markers , vol.14 , Issue.3 , pp. 135-143
    • Younes, A.1    Carbone, A.2
  • 7
    • 13244300652 scopus 로고    scopus 로고
    • Impaired negative selection of T cells in Hodgkin's disease antigen CD30-deficient mice
    • Amakawa R, Hakem A, Kundig TM, et al. Impaired negative selection of T cells in Hodgkin's disease antigen CD30-deficient mice. Cell 1996; 84:551-562.
    • (1996) Cell , vol.84 , pp. 551-562
    • Amakawa, R.1    Hakem, A.2    Kundig, T.M.3
  • 8
    • 0034541174 scopus 로고    scopus 로고
    • The TNF receptor family member CD30 is not essential for negative selection
    • DeYoung AL, Duramad O, Winoto A. The TNF receptor family member CD30 is not essential for negative selection. J Immunol 2000; 165:6170-6173.
    • (2000) J Immunol , vol.165 , pp. 6170-6173
    • Deyoung, A.L.1    Duramad, O.2    Winoto, A.3
  • 10
    • 79961133166 scopus 로고    scopus 로고
    • Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice
    • Gaspal F, Withers D, Saini M, et al. Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice. J Exp Med 2011; 208:1579-1584.
    • (2011) J Exp Med , vol.208 , pp. 1579-1584
    • Gaspal, F.1    Withers, D.2    Saini, M.3
  • 11
    • 0033602420 scopus 로고    scopus 로고
    • Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells
    • Kurts C, Carbone FR, Krummel MF, et al. Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells. Nature 1999; 398:341-344.
    • (1999) Nature , vol.398 , pp. 341-344
    • Kurts, C.1    Carbone, F.R.2    Krummel, M.F.3
  • 12
    • 0033711184 scopus 로고    scopus 로고
    • The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137
    • Lyons PA, Hancock WW, Denny P, et al. The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137. Immunity 2000; 13:107-115.
    • (2000) Immunity , vol.13 , pp. 107-115
    • Lyons, P.A.1    Hancock, W.W.2    Denny, P.3
  • 13
    • 0028206877 scopus 로고
    • Pleiotropic effects of the CD30 ligand on CD30-expressing cells and lymphoma cell lines
    • Gruss HJ, Boiani N, Williams DE, et al. Pleiotropic effects of the CD30 ligand on CD30-expressing cells and lymphoma cell lines. Blood 1994; 83:2045-2056. (Pubitemid 24112714)
    • (1994) Blood , vol.83 , Issue.8 , pp. 2045-2056
    • Gruss, H.-J.1    Boiani, N.2    Williams, D.E.3    Armitage, R.J.4    Smith, C.A.5    Goodwin, R.G.6
  • 15
    • 0034672237 scopus 로고    scopus 로고
    • Differential effects of CD30 activation in anaplastic large cell lymphoma and Hodgkin disease cells
    • Mir SS, Richter BW, Duckett CS. Differential effects of CD30 activation in anaplastic large cell lymphoma and Hodgkin disease cells. Blood 2000; 96:4307-4312.
    • (2000) Blood , vol.96 , pp. 4307-4312
    • Mir, S.S.1    Richter, B.W.2    Duckett, C.S.3
  • 16
    • 0033845174 scopus 로고    scopus 로고
    • Involvement of Sp1 and microsatellite repressor sequences in the transcriptional control of the human CD30 gene
    • Croager EJ, Gout AM, Abraham LJ. Involvement of Sp1 and microsatellite repressor sequences in the transcriptional control of the human CD30 gene. Am J Pathol 2000; 156:1723-1731. (Pubitemid 30648881)
    • (2000) American Journal of Pathology , vol.156 , Issue.5 , pp. 1723-1731
    • Croager, E.J.1    Gout, A.M.2    Abraham, L.J.3
  • 17
    • 77958596106 scopus 로고    scopus 로고
    • The class-I HDAC inhibitor MGCD0103 induces apoptosis in Hodgkin lymphoma cell lines and synergizes with proteasome inhibitors by an HDAC6-independent mechanism
    • Buglio D, Mamidipudi V, Khaskhely NM, et al. The class-I HDAC inhibitor MGCD0103 induces apoptosis in Hodgkin lymphoma cell lines and synergizes with proteasome inhibitors by an HDAC6-independent mechanism. Br J Haematol 2010; 151:387-396.
    • (2010) Br J Haematol , vol.151 , pp. 387-396
    • Buglio, D.1    Mamidipudi, V.2    Khaskhely, N.M.3
  • 19
    • 0025833281 scopus 로고
    • Clinical significance of soluble CD30 antigen in the sera of patients with untreated Hodgkin's disease
    • Gause A, Pohl C, Tschiersch A, et al. Clinical significance of soluble CD30 antigen in the sera of patients with untreated Hodgkin's disease. Blood 1991; 77:1983-1988.
    • (1991) Blood , vol.77 , pp. 1983-1988
    • Gause, A.1    Pohl, C.2    Tschiersch, A.3
  • 21
    • 0032387839 scopus 로고    scopus 로고
    • CD30: Expression and function in health and disease
    • DOI 10.1006/smim.1998.0156
    • Horie R, Watanabe T. CD30: expression and function in health and disease. Semin Immunol 1998; 10:457-470. (Pubitemid 28564375)
    • (1998) Seminars in Immunology , vol.10 , Issue.6 , pp. 457-470
    • Horie, R.1    Watanabe, T.2
  • 22
    • 0142026056 scopus 로고    scopus 로고
    • Emerging applications of the tumor necrosis factor family of ligands and receptors in cancer therapy
    • DOI 10.1200/JCO.2003.09.037
    • Younes A, Kadin ME. Emerging applications of the tumor necrosis factor family of ligands and receptors in cancer therapy. J Clin Oncol 2003; 21:3526-3534. (Pubitemid 46594087)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.18 , pp. 3526-3534
    • Younes, A.1    Kadin, M.E.2
  • 23
    • 0028879746 scopus 로고
    • CD30 expression in normal and neoplastic lymphoid tissue: Biological aspects and clinical implications
    • de Bruin PC, Gruss HJ, van der Valk P, et al. CD30 expression in normal and neoplastic lymphoid tissue: biological aspects and clinical implications. Leukemia 1995; 9:1620-1627.
    • (1995) Leukemia , vol.9 , pp. 1620-1627
    • De Bruin, P.C.1    Gruss, H.J.2    Van Der Valk, P.3
  • 30
    • 0026587530 scopus 로고
    • Response of refractory Hodgkin's disease to monoclonal anti-CD30 immunotoxin
    • Falini B, Bolognesi A, Flenghi L, et al. Response of refractory Hodgkin's disease to monoclonal anti-CD30 immunotoxin. Lancet 1992; 339:1195-1196.
    • (1992) Lancet , vol.339 , pp. 1195-1196
    • Falini, B.1    Bolognesi, A.2    Flenghi, L.3
  • 31
    • 0037962020 scopus 로고    scopus 로고
    • Clinical implications of the tumor necrosis factor family in benign and malignant hematologic disorders: A short review
    • DOI 10.1002/cncr.11524
    • Younes A, Aggarwall BB. Clinical implications of the tumor necrosis factor family in benign and malignant hematologic disorders. Cancer 2003; 98:458-467. (Pubitemid 36885984)
    • (2003) Cancer , vol.98 , Issue.3 , pp. 458-467
    • Younes, A.1    Aggarwall, B.B.2
  • 37
    • 79551588807 scopus 로고    scopus 로고
    • Beyond chemotherapy: New agents for targeted treatment of lymphoma
    • Younes A. Beyond chemotherapy: new agents for targeted treatment of lymphoma. Nat Rev Clin Oncol 2011; 8:85-96.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 85-96
    • Younes, A.1
  • 38
    • 33748098678 scopus 로고    scopus 로고
    • A humanized anti-CD30 monoclonal antibody, XmAbTM2513, with enhanced in vitro potency against CD30-positive lymphomas mediated by high affinity Fc-receptor binding
    • Hammond PW, Vafa O, Jacinto J, et al. A humanized anti-CD30 monoclonal antibody, XmAbTM2513, with enhanced in vitro potency against CD30-positive lymphomas mediated by high affinity Fc-receptor binding. Blood (ASH Annual Meeting Abstracts) 2005; 106:1470.
    • (2005) Blood (ASH Annual Meeting Abstracts) , vol.106 , pp. 1470
    • Hammond, P.W.1    Vafa, O.2    Jacinto, J.3
  • 39
    • 77958463143 scopus 로고    scopus 로고
    • XmAbTM2513, an Fc engineered humanized anti-CD30 monoclonal antibody, has potent in vitro and in vivo activities, and has the potential for treating hematologic malignancies
    • Lawrence CE, Hammond PW, Zalevsky J, et al. XmAbTM2513, an Fc engineered humanized anti-CD30 monoclonal antibody, has potent in vitro and in vivo activities, and has the potential for treating hematologic malignancies. Blood (ASH Annual Meeting Abstracts) 2007; 110:2340.
    • (2007) Blood (ASH Annual Meeting Abstracts) , vol.110 , pp. 2340
    • Lawrence, C.E.1    Hammond, P.W.2    Zalevsky, J.3
  • 40
    • 79956202280 scopus 로고    scopus 로고
    • Evaluation of the pharmacokinetics, immunogenicity, and safety of XmAb(R)2513 in the ongoing study XmAb2513-01: A phase 1 study of every other week xmab2513 to evaluate the safety, tolerability, and pharmacokinetics in patients with hodgkin lymphoma or anaplastic large cell lymphoma
    • Younes A, Zalevsky J, Blum KA, et al. Evaluation of the pharmacokinetics, immunogenicity, and safety of XmAb(R)2513 in the ongoing study XmAb2513-01: a phase 1 study of every other week xmab2513 to evaluate the safety, tolerability, and pharmacokinetics in patients with hodgkin lymphoma or anaplastic large cell lymphoma. Blood (ASH Annual Meeting Abstracts) 2008; 112:5012.
    • (2008) Blood (ASH Annual Meeting Abstracts) , vol.112 , pp. 5012
    • Younes, A.1    Zalevsky, J.2    Blum, K.A.3
  • 41
    • 76749151760 scopus 로고    scopus 로고
    • Phase i study of an anti-CD30 Fc engineered humanized monoclonal antibody in Hodgkin lymphoma (HL) or anaplastic large cell lymphoma (ALCL) patients: Safety, pharmacokinetics (PK), immunogenicity, and efficacy
    • Blum KA, Smith M, Fung H, et al. Phase I study of an anti-CD30 Fc engineered humanized monoclonal antibody in Hodgkin lymphoma (HL) or anaplastic large cell lymphoma (ALCL) patients: safety, pharmacokinetics (PK), immunogenicity, and efficacy. ASCO Meeting (abstracts) 2009; 27:8531.
    • (2009) ASCO Meeting (Abstracts) , vol.27 , pp. 8531
    • Blum, K.A.1    Smith, M.2    Fung, H.3
  • 43
    • 44649184200 scopus 로고    scopus 로고
    • Combination of the anti-CD30-auristatin-E antibody-drug conjugate (SGN-35) with chemotherapy improves antitumour activity in Hodgkin lymphoma
    • DOI 10.1111/j.1365-2141.2008.07146.x
    • Oflazoglu E, Kissler KM, Sievers EL, et al. Combination of the anti-CD30-auristatin-E antibody-drug conjugate (SGN-35) with chemotherapy improves antitumour activity in Hodgkin lymphoma. Br J Haematol 2008; 142:69-73. (Pubitemid 351783148)
    • (2008) British Journal of Haematology , vol.142 , Issue.1 , pp. 69-73
    • Oflazoglu, E.1    Kissler, K.M.2    Sievers, E.L.3    Grewal, I.S.4    Gerber, H.-P.5
  • 44
    • 76049122850 scopus 로고    scopus 로고
    • Intracellular activation of SGN-35, a potent anti-CD30 antibody-drug conjugate
    • Okeley NM, Miyamoto JB, Zhang X, et al. Intracellular activation of SGN-35, a potent anti-CD30 antibody-drug conjugate. Clin Cancer Res 2010; 16: 888-897.
    • (2010) Clin Cancer Res , vol.16 , pp. 888-897
    • Okeley, N.M.1    Miyamoto, J.B.2    Zhang, X.3
  • 46
    • 78049515807 scopus 로고    scopus 로고
    • Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas
    • Younes A, Bartlett NL, Leonard JP, et al. Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas. N Engl J Med 2010; 363:1812-1821.
    • (2010) N Engl J Med , vol.363 , pp. 1812-1821
    • Younes, A.1    Bartlett, N.L.2    Leonard, J.P.3
  • 47
    • 70349645442 scopus 로고    scopus 로고
    • Complete remissions with weekly dosing of SGN-35, a novel antibody-drug conjugate (ADC) targeting CD30, in a phase i dose-escalation study in patients with relapsed or refractory Hodgkin lymphoma (HL) or systemic anaplastic large cell lymphoma (sALCL)
    • Bartlett N, Forero-Torres A, Rosenblatt J, et al. Complete remissions with weekly dosing of SGN-35, a novel antibody-drug conjugate (ADC) targeting CD30, in a phase I dose-escalation study in patients with relapsed or refractory Hodgkin lymphoma (HL) or systemic anaplastic large cell lymphoma (sALCL). ASCO Meeting Abstracts 2009; 27:8500.
    • (2009) ASCO Meeting Abstracts , vol.27 , pp. 8500
    • Bartlett, N.1    Forero-Torres, A.2    Rosenblatt, J.3
  • 48
    • 80054101992 scopus 로고    scopus 로고
    • Results from a pivotal phase II study of brentuximab vedotin (SGN-35) in patients with relapsed or refractory Hodgkin lymphoma (HL)
    • Chen RW, Gopal AK, Smith SE, et al. Results from a pivotal phase II study of brentuximab vedotin (SGN-35) in patients with relapsed or refractory Hodgkin lymphoma (HL). ASCO Meeting Abstracts 2011; 29:8031.
    • (2011) ASCO Meeting Abstracts , vol.29 , pp. 8031
    • Chen, R.W.1    Gopal, A.K.2    Smith, S.E.3
  • 49
    • 80053190602 scopus 로고    scopus 로고
    • Durable remissions with brentuximab vedotin (SGN-35): Updated results of a phase II study in patients with relapsed or refractory systemic anaplastic large cell lymphoma (sALCL)
    • Pro B, Advani R, Brice P, et al. Durable remissions with brentuximab vedotin (SGN-35): Updated results of a phase II study in patients with relapsed or refractory systemic anaplastic large cell lymphoma (sALCL). ASCO Meeting Abstracts; 29:8032.
    • ASCO Meeting Abstracts , vol.29 , pp. 8032
    • Pro, B.1    Advani, R.2    Brice, P.3
  • 50
    • 67649908324 scopus 로고    scopus 로고
    • A phase II study of SGN-30 (anti-CD30 mAb) in Hodgkin lymphoma or systemic anaplastic large cell lymphoma
    • Forero-Torres A, Leonard JP, Younes A, et al. A phase II study of SGN-30 (anti-CD30 mAb) in Hodgkin lymphoma or systemic anaplastic large cell lymphoma. Br J Haematol 2009; 146:171-179.
    • (2009) Br J Haematol , vol.146 , pp. 171-179
    • Forero-Torres, A.1    Leonard, J.P.2    Younes, A.3
  • 51
    • 77955311034 scopus 로고    scopus 로고
    • The antibody-drug conjugate brentuximab vedotin (SGN-35) induced multiple objective responses in patients with relapsed or refractory CD30-positive lymphomas in a phase 1. weekly dosing study
    • Fanale M, Bartlett NL, Forero-Torres A, et al. The antibody-drug conjugate brentuximab vedotin (SGN-35) induced multiple objective responses in patients with relapsed or refractory CD30-positive lymphomas in a phase 1. weekly dosing study. Blood (ASH Annual Meeting Abstracts). 2009; 114:2731.
    • (2009) Blood (ASH Annual Meeting Abstracts). , vol.114 , pp. 2731
    • Fanale, M.1    Bartlett, N.L.2    Forero-Torres, A.3
  • 52
    • 78650275149 scopus 로고    scopus 로고
    • Objective responses with brentuximab vedotin (SGN-35) retreatment in CD30-positive hematologic malignancies: A case series
    • Bartlett N, Grove LE, Kennedy DA, et al. Objective responses with brentuximab vedotin (SGN-35) retreatment in CD30-positive hematologic malignancies: a case series. ASCO Meeting Abstracts 2010; 28:8062.
    • (2010) ASCO Meeting Abstracts , vol.28 , pp. 8062
    • Bartlett, N.1    Grove, L.E.2    Kennedy, D.A.3


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