Optimization by experimental design of an immediate release tablet formulation comprising metformin and glibenclamide

Farmacia

Volumn 59, Issue 5, 2011, Pages 690-699

  Roxana Georgiana, Potur ^a,b   Lǎcrǎmioara, Moisuc ^a   Tudor, Boiţǎ ^a   Eliza, Gafiţanu ^b   Mircea Dan, Potur ^c  

^a Pharmaceutical Development Department   (Romania)

^b GRIGORE T POPA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^c GHEORGHE ASACHI TECHNICAL UNIVERSITY OF IASI   (Romania)

Author keywords

Dissolution profile; Experimental design; Glibenclamide; Metformin; Tablets

Indexed keywords

GLIBENCLAMIDE PLUS METFORMIN; KEMILUB; LACTYTAB; PLASDONE S 630; UNCLASSIFIED DRUG; VIVAPUR 101; VIVASOL;

ARTICLE; CHEMICAL COMPOSITION; DRUG DELIVERY SYSTEM; DRUG QUALITY; DRUG SOLUBILITY; EXPERIMENTAL DESIGN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMEDIATE RELEASE PREPARATION; MATHEMATICAL MODEL; MULTIPLE LINEAR REGRESSION ANALYSIS; PARTICLE SIZE; PATIENT COMPLIANCE; TABLET COMPRESSION; TABLET DISINTEGRATION; TABLET FORMULATION; TABLET FRIABILITY; TABLET HARDNESS; WEIGHT;

EID: 80054107293     PISSN: 00148237     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

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6. Cristina Georgiţǎ, Iulia Sora, Florin Albu, Crina Maria Monciu, Comparison of a LC/MS method with a LC/UV method for the determination of metformin in plasma samples, Farmacia, 2010, 58(2), 158-169.