메뉴 건너뛰기




Volumn 12, Issue 12, 2011, Pages 1792-1804

Historical observations on the discovery of platelets, platelet function testing and the first antiplatelet agent

Author keywords

Aggregometry; Aspirin; History; Platelet

Indexed keywords

ACETYLSALICYLIC ACID; BENZENE; CAFFEINE; CINCHONA BARK; FERROCYANIDE; MORPHINE; PLACEBO; QUININE; SALICIN; SALICYLIC ACID; STRYCHNINE;

EID: 80054084447     PISSN: 13894501     EISSN: 18735592     Source Type: Journal    
DOI: 10.2174/138945011797635858     Document Type: Article
Times cited : (12)

References (66)
  • 1
    • 84861226200 scopus 로고    scopus 로고
    • World Health Organization. updated September, Available from
    • World Health Organization. [updated September 2009]; Available from: http://www.who.int/mediacentre/factsheets/fs317/en/index. html
    • (2009)
  • 2
    • 0642279303 scopus 로고    scopus 로고
    • A note from history: The discovery of blood cells
    • Hajdu SI. A note from history: the discovery of blood cells. Ann Clin Lab Sci 2003; 33(2): 237-8.
    • (2003) Ann Clin Lab Sci , vol.33 , Issue.2 , pp. 237-238
    • Hajdu, S.I.1
  • 3
    • 0009132916 scopus 로고
    • Historical notes on blood platelets
    • Tocantins LM. Historical notes on blood platelets. Blood 1948; 3(10): 1073-82.
    • (1948) Blood , vol.3 , Issue.10 , pp. 1073-1082
    • Tocantins, L.M.1
  • 4
    • 0014105854 scopus 로고
    • Why the platelets were discovered
    • Robb-Smith AH. Why the platelets were discovered. Br J Haematol 1967; 13(4): 618-37.
    • (1967) Br J Haematol , vol.13 , Issue.4 , pp. 618-637
    • Robb-Smith, A.H.1
  • 5
    • 0345401064 scopus 로고
    • On the colourless corpuscles and on molecules and cytoblasts in the blood
    • Addison W. On the colourless corpuscles and on molecules and cytoblasts in the blood. Lond Med Gazz 1842; 30: 144.
    • (1842) Lond Med Gazz , vol.30 , pp. 144
    • Addison, W.1
  • 6
    • 80054064318 scopus 로고
    • On the socalled New Element of the blood and its relation to coagulation
    • Studies From the Biological Laboratory: Johns Hopkins University
    • Kemp G. On the socalled New Element of the blood and its relation to coagulation. Studies from the Biological Laboratory: Johns Hopkins University 1886; 3: pp. 293-349.
    • (1886) , vol.3 , pp. 293-349
    • Kemp, G.1
  • 7
    • 33645450196 scopus 로고    scopus 로고
    • Max Schultze (1865), G. Bizzozero (1882) and the discovery of the platelet
    • Brewer DB. Max Schultze (1865), G. Bizzozero (1882) and the discovery of the platelet. Br J Haematol 2006; 133(3): 251-8.
    • (2006) Br J Haematol , vol.133 , Issue.3 , pp. 251-258
    • Brewer, D.B.1
  • 8
    • 80054081003 scopus 로고
    • On the action of certain reagents, atrophia, physostigma and curare on the colorless blood corpuscles
    • Osler W. On the action of certain reagents, atrophia, physostigma and curare on the colorless blood corpuscles. Q J Med Sci 1873; 13: 307-9.
    • (1873) Q J Med Sci , vol.13 , pp. 307-309
    • Osler, W.1
  • 9
    • 0011542171 scopus 로고
    • An account of certain organisms occurring in the liquor sanguinis
    • Osler W. An account of certain organisms occurring in the liquor sanguinis. Proc Roy Soc 1874; 22: 391-8.
    • (1874) Proc Roy Soc , vol.22 , pp. 391-398
    • Osler, W.1
  • 10
    • 0028027701 scopus 로고
    • Bizzozero and the discovery of platelets
    • Dianzani MU. Bizzozero and the discovery of platelets. Am J Nephrol 1994; 14(4-6): 330-6.
    • (1994) Am J Nephrol , vol.14 , Issue.4-6 , pp. 330-336
    • Dianzani, M.U.1
  • 11
    • 0001574361 scopus 로고
    • A new blood corpuscle
    • Anonymous
    • Anonymous. A new blood corpuscle. Lancet 1882; i: 111-2.
    • (1882) Lancet , vol.i , pp. 111-112
  • 12
    • 0000105161 scopus 로고
    • Su di un nuovo elemento morfologico del sangue dei mammiferi e dellasua importanza nella trombosi e nella coagulazione
    • Bizzozero G. Su di un nuovo elemento morfologico del sangue dei mammiferi e dellasua importanza nella trombosi e nella coagulazione. Osserv Gazz Clin 1881; 17: 785-7.
    • (1881) Osserv Gazz Clin , vol.17 , pp. 785-787
    • Bizzozero, G.1
  • 13
    • 0141924846 scopus 로고
    • The third corpuscle of the blood
    • Osler W. The third corpuscle of the blood. Med News Phil 1883; 43: 701-2.
    • (1883) Med News Phil , vol.43 , pp. 701-702
    • Osler, W.1
  • 14
    • 34447593677 scopus 로고
    • Ueber einen neuen forrnbestandteil des blutes und dessen rolle bei der thrombose und blutgerinnung
    • Bizzozero J. Julius bizzozero: on a new blood particle and its role in thrombosis and blood coagulation. Translation of: Ueber einen neuen forrnbestandteil des blutes und dessen rolle bei der thrombose und blutgerinnung. Virchows Arch Path Anat Physiol Klin Med 1882; 90: 261-332.
    • (1882) Virchows Arch Path Anat Physiol Klin Med , vol.90 , pp. 261-332
    • Bizzozero, J.1
  • 15
    • 50549132616 scopus 로고
    • On the claim of Professor Bizzozero to the discovery of the fibrin-forming corpuscle of the blood
    • Norris R. On the claim of Professor Bizzozero to the discovery of the fibrin-forming corpuscle of the blood. Lancet 1882; 119: 561-2.
    • (1882) Lancet , vol.119 , pp. 561-562
    • Norris, R.1
  • 16
    • 0034768057 scopus 로고    scopus 로고
    • A new blood corpuscle: An impossible interview with Giulio Bizzozero
    • de Gaetano G. A new blood corpuscle: an impossible interview with Giulio Bizzozero. Thromb Haemost 2001; 86(4): 973-9.
    • (2001) Thromb Haemost , vol.86 , Issue.4 , pp. 973-979
    • de Gaetano, G.1
  • 17
    • 0006313182 scopus 로고
    • Influence de la peau sur la coagulabilite du sang
    • Millian M. Influence de la peau sur la coagulabilite du sang. C R Soc Biol Paris 1901; 53: 576-8.
    • (1901) C R Soc Biol Paris , vol.53 , pp. 576-578
    • Millian, M.1
  • 18
    • 84940138412 scopus 로고
    • The relationship of blood platelets to hemorrhagic disease. Description of a method for determining the bleeding time and coagulation time and report of three cases of hemorrhagic disease relieved by transfusions
    • Duke WW. The relationship of blood platelets to hemorrhagic disease. Description of a method for determining the bleeding time and coagulation time and report of three cases of hemorrhagic disease relieved by transfusions. JAMA 1910; 55: 1185-92.
    • (1910) JAMA , vol.55 , pp. 1185-1192
    • Duke, W.W.1
  • 19
    • 0005092889 scopus 로고
    • The standardization of certain factors in the cutaneous "venostasis" bleeding time technique
    • Ivy AC, Nelson D, Buchet G. The standardization of certain factors in the cutaneous "venostasis" bleeding time technique. J Lab Clin Med 1941; 26: 1812-22.
    • (1941) J Lab Clin Med , vol.26 , pp. 1812-1822
    • Ivy, A.C.1    Nelson, D.2    Buchet, G.3
  • 20
    • 0031892624 scopus 로고    scopus 로고
    • The preoperative bleeding time test lacks clinical benefit: College of American Pathologists' and American Society of Clinical Pathologists' position article
    • Peterson P, Hayes TE, Arkin CF, et al. The preoperative bleeding time test lacks clinical benefit: College of American Pathologists' and American Society of Clinical Pathologists' position article. Arch Surg 1998; 133(2): 134-9.
    • (1998) Arch Surg , vol.133 , Issue.2 , pp. 134-139
    • Peterson, P.1    Hayes, T.E.2    Arkin, C.F.3
  • 21
    • 18044388905 scopus 로고    scopus 로고
    • Preclinical and clinical studies with selective reversible direct P2Y12 antagonists
    • van Giezen JJ, Humphries RG. Preclinical and clinical studies with selective reversible direct P2Y12 antagonists. Semin Thromb Hemost 2005; 31(2): 195-204.
    • (2005) Semin Thromb Hemost , vol.31 , Issue.2 , pp. 195-204
    • van Giezen, J.J.1    Humphries, R.G.2
  • 22
    • 50349107826 scopus 로고
    • The stickiness of platelets
    • Baar HS. The stickiness of platelets. Lancet 1941; 238(6173): 775.
    • (1941) Lancet , vol.238 , Issue.6173 , pp. 775
    • Baar, H.S.1
  • 23
    • 34347148288 scopus 로고
    • Uber die Plattchenzerfallsgeschwindigkeit bei normalen Kindem, bei Harnophilie und Thrombopenie
    • Baar HS, Szekely L. Uber die Plattchenzerfallsgeschwindigkeit bei normalen Kindem, bei Harnophilie und Thrombopenie. Z Kinderheilk 1929; 43: 31-42.
    • (1929) Z Kinderheilk , vol.43 , pp. 31-42
    • Baar, H.S.1    Szekely, L.2
  • 24
    • 80054089017 scopus 로고
    • Gibt es eine Thrombasthenie
    • Morawitz P, Jurgens R. Gibt es eine Thrombasthenie. Munch med Wschr 1930; 77: 2001-3.
    • (1930) Munch Med Wschr , vol.77 , pp. 2001-2003
    • Morawitz, P.1    Jurgens, R.2
  • 25
    • 27644434304 scopus 로고
    • The adhesiveness of blood platelets in normal subjects with varying concentrations of anti-coagulants
    • Wright HP. The adhesiveness of blood platelets in normal subjects with varying concentrations of anti-coagulants. J Path Bact 1941; 53: 255-62.
    • (1941) J Path Bact , vol.53 , pp. 255-262
    • Wright, H.P.1
  • 26
    • 0005314491 scopus 로고
    • Changes in the adhesiveness of blood platelets following parturition and surgical operations
    • Wright HP. Changes in the adhesiveness of blood platelets following parturition and surgical operations. J Path Bact 1942; 54: 461-8.
    • (1942) J Path Bact , vol.54 , pp. 461-468
    • Wright, H.P.1
  • 27
    • 0001803529 scopus 로고
    • The adhesiveness of human platelets in vivo
    • Hellem AJ. The adhesiveness of human platelets in vivo. Scand J Clin Lab Invest 1960; 12(Suppl 51): 1-117.
    • (1960) Scand J Clin Lab Invest , vol.12 , Issue.SUPPL. 51 , pp. 1-117
    • Hellem, A.J.1
  • 28
    • 0000815257 scopus 로고
    • Adenosine diphosphate in red cells as a factor in the adhesiveness of human blood platelets
    • Gaarder A, Jonsen J, Laland S, Hellem A, Owren PA. Adenosine diphosphate in red cells as a factor in the adhesiveness of human blood platelets. Nature 1961; 192: 531-2.
    • (1961) Nature , vol.192 , pp. 531-532
    • Gaarder, A.1    Jonsen, J.2    Laland, S.3    Hellem, A.4    Owren, P.A.5
  • 29
    • 78651139188 scopus 로고
    • The aggregation of blood platelets
    • Born GV, Cross MJ. The aggregation of blood platelets. J Physiol 1963; 168: 178-95.
    • (1963) J Physiol , vol.168 , pp. 178-195
    • Born, G.V.1    Cross, M.J.2
  • 32
    • 27844481087 scopus 로고    scopus 로고
    • Light on platelets
    • Born GV. Light on platelets. J Physiol 2005; 568(Pt 3): 713-4.
    • (2005) J Physiol , vol.568 , Issue.Pt 3 , pp. 713-714
    • Born, G.V.1
  • 33
    • 0346367328 scopus 로고
    • Aggregation of blood platelets by adenosine diphosphate and its reversal
    • Born GV. Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature 1962; 194: 927-9.
    • (1962) Nature , vol.194 , pp. 927-929
    • Born, G.V.1
  • 34
    • 0002301506 scopus 로고
    • Quantitative investigations into the aggregation of blood platelets
    • Born GV. Quantitative investigations into the aggregation of blood platelets. J Physiol 1962; 162: 67P-8P.
    • (1962) J Physiol , vol.162
    • Born, G.V.1
  • 35
    • 0001332609 scopus 로고
    • Platelet aggregation: Part II some results from a new method of study
    • O'Brien JR. Platelet aggregation: Part II some results from a new method of study. J Clin Pathol 1962; 15: 452-5.
    • (1962) J Clin Pathol , vol.15 , pp. 452-455
    • O'Brien, J.R.1
  • 36
    • 84861224360 scopus 로고    scopus 로고
    • Welcome Trust Centre for the History of Medicine at UCL
    • The Recent History of Platelets in Thrombosis and Other Disorders
    • The Recent History of Platelets in Thrombosis and Other Disorders. Welcome Trust Centre for the History of Medicine at UCL. Witness Seminar; London 2003. www.ucl.ac.uk/histmed
    • (2003) Witness Seminar; London
  • 39
    • 0001187267 scopus 로고
    • An account of the success of the bark of the willow in the cure of agues
    • Stone E. An account of the success of the bark of the willow in the cure of agues. Philos Trans R Soc Lond [Biol] 1763; 53: 195-200.
    • (1763) Philos Trans R Soc Lond [Biol] , vol.53 , pp. 195-200
    • Stone, E.1
  • 40
    • 50449174264 scopus 로고
    • The treatment of acute rheumatism by salicin
    • Maclagan T. The treatment of acute rheumatism by salicin. Lancet 1876; 107(2741): 383-4.
    • (1876) Lancet , vol.107 , Issue.2741 , pp. 383-384
    • Maclagan, T.1
  • 41
    • 0034707245 scopus 로고    scopus 로고
    • The discovery of aspirin: A reappraisal
    • Sneader W. The discovery of aspirin: a reappraisal. BMJ 2000; 321(7276): 1591-4.
    • (2000) BMJ , vol.321 , Issue.7276 , pp. 1591-1594
    • Sneader, W.1
  • 42
    • 1642457088 scopus 로고
    • Hemorrhagic complications with death probably from salicylate therapy
    • Ashworth CT, McKemie. Hemorrhagic complications with death probably from salicylate therapy. JAMA 1944; 126(13): 806-10.
    • (1944) JAMA , vol.126 , Issue.13 , pp. 806-810
    • Ashworth, C.T.1    McKemie2
  • 43
    • 34248355639 scopus 로고
    • Salicylates and hemorrhage
    • Quick AJ. Salicylates and hemorrhage. JAMA 1944; 126: 1167.
    • (1944) JAMA , vol.126 , pp. 1167
    • Quick, A.J.1
  • 44
    • 0009322367 scopus 로고
    • Acetylsalicylic acid, possible prevention of coronary thrombosis
    • Craven LL. Acetylsalicylic acid, possible prevention of coronary thrombosis. Ann West Med Surg 1950; 4(2): 95-9.
    • (1950) Ann West Med Surg , vol.4 , Issue.2 , pp. 95-99
    • Craven, L.L.1
  • 45
    • 0343629781 scopus 로고
    • Salicylic acid for coronary thrombosis?
    • Gibson P. Salicylic acid for coronary thrombosis? Lancet 1948; 1: 965.
    • (1948) Lancet , vol.1 , pp. 965
    • Gibson, P.1
  • 46
    • 50349108416 scopus 로고
    • Aspirin in the treatment of vascular diseases
    • Gibson PC. Aspirin in the treatment of vascular diseases. Lancet 1949; 2: 1172-4.
    • (1949) Lancet , vol.2 , pp. 1172-1174
    • Gibson, P.C.1
  • 47
    • 80054062930 scopus 로고
    • Salicylates and anticoagulant therapy
    • Gibson PC. Salicylates and anticoagulant therapy. Br Med J 1955; 1(4920): 1028.
    • (1955) Br Med J , vol.1 , Issue.4920 , pp. 1028
    • Gibson, P.C.1
  • 48
    • 33845462556 scopus 로고
    • Experiences with aspirin (acetylsalicylic acid) in the nonspecific prophylaxis of coronary thrombosis
    • Craven LL. Experiences with aspirin (acetylsalicylic acid) in the nonspecific prophylaxis of coronary thrombosis. Miss Valley Med J 1953; 75: 38-44.
    • (1953) Miss Valley Med J , vol.75 , pp. 38-44
    • Craven, L.L.1
  • 49
    • 0000144179 scopus 로고
    • Prevention of coronary and cerebral thrombosis
    • Craven LL. Prevention of coronary and cerebral thrombosis. Miss Valley Med J 1956; 78: 213-5.
    • (1956) Miss Valley Med J , vol.78 , pp. 213-215
    • Craven, L.L.1
  • 50
    • 0013951558 scopus 로고
    • Salicylates and bleeding: The aspirin tolerance test
    • Quick AJ. Salicylates and bleeding: the aspirin tolerance test. Am J Med Sci 1966; 252(3): 265-9.
    • (1966) Am J Med Sci , vol.252 , Issue.3 , pp. 265-269
    • Quick, A.J.1
  • 51
    • 0000688132 scopus 로고
    • Acetylsalicylic acid and platelet stickiness
    • Morris CDW. Acetylsalicylic acid and platelet stickiness. Lancet 1967; 1: 279-80.
    • (1967) Lancet , vol.1 , pp. 279-280
    • Morris, C.D.W.1
  • 52
    • 0014190795 scopus 로고
    • Impaired platelet-connective-tissue reaction in man after aspirin ingestion
    • Weiss HJ, Aledort LM. Impaired platelet-connective-tissue reaction in man after aspirin ingestion. Lancet 1967; 290(7514): 495-7.
    • (1967) Lancet , vol.290 , Issue.7514 , pp. 495-497
    • Weiss, H.J.1    Aledort, L.M.2
  • 53
    • 2442561675 scopus 로고    scopus 로고
    • The discovery of the antiplatelet effect of aspirin: A personal reminiscence
    • Weiss HJ. The discovery of the antiplatelet effect of aspirin: a personal reminiscence. J Thromb Haemost 2003; 1(9): 1869-75.
    • (2003) J Thromb Haemost , vol.1 , Issue.9 , pp. 1869-1875
    • Weiss, H.J.1
  • 55
    • 0014334649 scopus 로고
    • The effect of salicylates on the hemostatic properties of platelets in man
    • Weiss HJ, Aledort LM, Kochwa S. The effect of salicylates on the hemostatic properties of platelets in man. J Clin Invest 1968; 47(9): 2169-80.
    • (1968) J Clin Invest , vol.47 , Issue.9 , pp. 2169-2180
    • Weiss, H.J.1    Aledort, L.M.2    Kochwa, S.3
  • 56
    • 0014412573 scopus 로고
    • Effects of salicylates on human platelets
    • O'Brien JR. Effects of salicylates on human platelets. Lancet 1968; 1(7546): 779-83.
    • (1968) Lancet , vol.1 , Issue.7546 , pp. 779-783
    • O'Brien, J.R.1
  • 57
    • 0014249814 scopus 로고
    • Inhibition of adenosine diphosphate- induced secondary aggregation and other platelet functions by acetylsalicylic acid ingestion
    • Zucker MB, Peterson J. Inhibition of adenosine diphosphate- induced secondary aggregation and other platelet functions by acetylsalicylic acid ingestion. Proc Soc Exp Biol Med 1968; 127(2): 547-51.
    • (1968) Proc Soc Exp Biol Med , vol.127 , Issue.2 , pp. 547-551
    • Zucker, M.B.1    Peterson, J.2
  • 58
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 1971; 231: 231-5.
    • (1971) Nat New Biol , vol.231 , pp. 231-235
    • Vane, J.R.1
  • 59
    • 0015237275 scopus 로고
    • Aspirin selectively inhibits prostaglandin production in human platelets
    • Smith JB, Willis AL. Aspirin selectively inhibits prostaglandin production in human platelets. Nat New Biol 1971; 231: 235-7.
    • (1971) Nat New Biol , vol.231 , pp. 235-237
    • Smith, J.B.1    Willis, A.L.2
  • 60
    • 84919587578 scopus 로고
    • Report of the Steering Committee of a trial sponsored by the Medical Research Council
    • Effect of aspirin on postoperative venous thrombosis
    • Effect of aspirin on postoperative venous thrombosis. Report of the Steering Committee of a trial sponsored by the Medical Research Council. Lancet 1972; 2(7775): 441-5.
    • (1972) Lancet , vol.2 , Issue.7775 , pp. 441-445
  • 61
    • 0015956225 scopus 로고
    • A randomized controlled trial of acetyl salicylic acid in the secondary prevention of mortality from myocardial infarction
    • Elwood P, Cochrane A, Burr M, et al. A randomized controlled trial of acetyl salicylic acid in the secondary prevention of mortality from myocardial infarction. BMJ 1974; 1(905): 436-40.
    • (1974) BMJ , vol.1 , Issue.905 , pp. 436-440
    • Elwood, P.1    Cochrane, A.2    Burr, M.3
  • 62
    • 0018892610 scopus 로고
    • Aspirin after myocardial infarction
    • Aspirin after myocardial infarction. Lancet 1980; 1(8179): 1172-3.
    • (1980) Lancet , vol.1 , Issue.8179 , pp. 1172-1173
  • 63
    • 0023805341 scopus 로고
    • Randomized trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction; ISIS-2
    • ISIS-2 (Second International Study of Infarct Survival) Collaborative Group
    • ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Randomized trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction; ISIS-2. Lancet 1988; 349-60.
    • (1988) Lancet , pp. 349-360
  • 64
    • 0020528647 scopus 로고
    • Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina: Results of a Veterans Administration Cooperative Study
    • Lewis Jr HD, Davis JW, Archibald DG, et al. Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina: Results of a Veterans Administration Cooperative Study. N Eng J Med 1983; 309: 396-403.
    • (1983) N Eng J Med , vol.309 , pp. 396-403
    • Lewis, H.D.1    Davis, J.W.2    Archibald, D.G.3
  • 66
    • 65849268320 scopus 로고    scopus 로고
    • Aspirin in the primary and secondary prevention of vascular disease: Collaborative meta-analysis of individual participant data from randomised trials
    • Baigent C, Blackwell L, Collins R, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet 2009; 373(9678): 1849-60.
    • (2009) Lancet , vol.373 , Issue.9678 , pp. 1849-1860
    • Baigent, C.1    Blackwell, L.2    Collins, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.