Case-control study of vitamin D, dickkopf homolog 1 (DKK1) gene methylation, VDR gene polymorphism and the risk of colon adenoma in African Americans

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Ashktorab, Hassan ^a   Nguza, Bijou ^a   Fatemi, Mehrnaz ^a   Nouraie, Mehdi ^b   Smoot, Duane T ^a   Schäffer, Alejandro A ^c   Kupfer, Sonia S ^d   Camargo Jr , Carlos A ^e   Brim, Hassan ^a  

^a HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b HOWARD UNIVERSITY   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYERGOCALCIFEROL; 25 HYDROXYVITAMIN D; CALCIFEDIOL; CALCITRIOL RECEPTOR; DKK1 PROTEIN, HUMAN; SIGNAL PEPTIDE; VITAMIN D;

ADULT; AFRICAN AMERICAN; AGED; ARTICLE; CASE CONTROL STUDY; COLON POLYP; CONTROLLED STUDY; DISEASE ASSOCIATION; DKK1 GENE; DNA METHYLATION; FEMALE; GENE; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MALE; PROMOTER REGION; RISK ASSESSMENT; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; VDR GENE; VITAMIN BLOOD LEVEL; ADENOMA; BLOOD; COLON TUMOR; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; RISK; SEASON;

ADENOMA; AFRICAN AMERICANS; AGED; CASE-CONTROL STUDIES; COLONIC NEOPLASMS; COLONIC POLYPS; DNA METHYLATION; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; RECEPTORS, CALCITRIOL; RISK FACTORS; SEASONS; VITAMIN D;

EID: 80054073118     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025314     Document Type: Article

References (45)

1. Jemal A, Center MM, Ward E, (2009) The convergence of lung cancer rates between blacks and whites under the age of 40, United States. Cancer Epidemiol Biomarkers Prev 18: 3349-3352.
2. Fearon ER, Vogelstein B, (1990) A genetic model for colorectal tumorigenesis. Cell 61: 759-767.
3. Jones S, Chen WD, Parmigiani G, Diehl F, Beerenwinkel N, et al. (2008) Comparative lesion sequencing provides insights into tumor evolution. Proc Natl Acad Sci U S A 105: 4283-4288.
4. Garland CF, Garland FC, (1980) Do sunlight and vitamin D reduce the likelihood of colon cancer? Int J Epidemiol 9: 227-231.
5. Garland CF, Gorham ED, Mohr SB, Garland FC, (2009) Vitamin D for cancer prevention: global perspective. Ann Epidemiol 19: 468-483.
6. Chan AT, Giovannucci EL, (2010) Primary prevention of colorectal cancer. Gastroenterology 138: 2029-2043 e2010.
7. Newmark HL, Yang K, Kurihara N, Fan K, Augenlicht LH, et al. (2009) Western-style diet-induced colonic tumors and their modulation by calcium and vitamin D in C57Bl/6 mice: a preclinical model for human sporadic colon cancer. Carcinogenesis 30: 88-92.
8. Dong LM, Ulrich CM, Hsu L, Duggan DJ, Benitez DS, et al. (2009) Vitamin D related genes, CYP24A1 and CYP27B1, and colon cancer risk. Cancer Epidemiol Biomarkers Prev 18: 2540-2548.
9. Jenab M, McKay J, Bueno-de-Mesquita HB, van Duijnhoven FJ, Ferrari P, et al. (2009) Vitamin D receptor and calcium sensing receptor polymorphisms and the risk of colorectal cancer in European populations. Cancer Epidemiol Biomarkers Prev 18: 2485-2491.
10. Mai V, McCrary QM, Sinha R, Glei M, (2009) Associations between dietary habits and body mass index with gut microbiota composition and fecal water genotoxicity: an observational study in African American and Caucasian American volunteers. Nutr J 8: 49.
11. Bronowski C, Smith SL, Yokota K, Corkill JE, Martin HM, et al. (2008) A subset of mucosa-associated Escherichia coli isolates from patients with colon cancer, but not Crohn's disease, share pathogenicity islands with urinary pathogenic E. coli. Microbiology 154: 571-583.
12. Mohr SB, (2009) A brief history of vitamin d and cancer prevention. Ann Epidemiol 19: 79-83.
13. Li C, Li Y, Gao LB, Wang YY, Zhou B, et al. (2009) Vitamin D receptor gene polymorphisms and the risk of colorectal cancer in a Chinese population. Dig Dis Sci 54: 634-639.
14. Barroso E, Fernandez LP, Milne RL, Pita G, Sendagorta E, et al. (2008) Genetic analysis of the vitamin D receptor gene in two epithelial cancers: melanoma and breast cancer case-control studies. BMC Cancer 8: 385.
15. Davis CD, (2008) Vitamin D and cancer: current dilemmas and future research needs. Am J Clin Nutr 88: 565S-569S.
16. McKay JD, McCullough ML, Ziegler RG, Kraft P, Saltzman BS, et al. (2009) Vitamin D receptor polymorphisms and breast cancer risk: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. Cancer Epidemiol Biomarkers Prev 18: 297-305.
17. Murtaugh MA, Sweeney C, Ma KN, Potter JD, Caan BJ, et al. (2006) Vitamin D receptor gene polymorphisms, dietary promotion of insulin resistance, and colon and rectal cancer. Nutr Cancer 55: 35-43.
18. Slattery ML, (2007) Vitamin D receptor gene (VDR) associations with cancer. Nutr Rev 65: S102-104.
19. Slattery ML, Sweeney C, Murtaugh M, Ma KN, Caan BJ, et al. (2006) Associations between vitamin D, vitamin D receptor gene and the androgen receptor gene with colon and rectal cancer. Int J Cancer 118: 3140-3146.
20. Slattery ML, Wolff RK, Curtin K, Fitzpatrick F, Herrick J, et al. (2009) Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways. Mutat Res 660: 12-21.
21. Tangpricha V, Spina C, Yao M, Chen TC, Wolfe MM, et al. (2005) Vitamin D deficiency enhances the growth of MC-26 colon cancer xenografts in Balb/c mice. J Nutr 135: 2350-2354.
22. Chen Q, Ross AC, (2005) Inaugural Article: Vitamin A and immune function: retinoic acid modulates population dynamics in antigen receptor and CD38-stimulated splenic B cells. Proc Natl Acad Sci U S A 102: 14142-14149.
23. Zhang C, Wang C, Liang J, Zhou X, Zheng F, et al. (2008) The vitamin D receptor Fok1 polymorphism and bone mineral density in Chinese children. Clin Chim Acta 395: 111-114.
24. Pendas-Franco N, Aguilera O, Pereira F, Gonzalez-Sancho JM, Munoz A, (2008) Vitamin D and Wnt/beta-catenin pathway in colon cancer: role and regulation of DICKKOPF genes. Anticancer Res 28: 2613-2623.
25. Sharma N, Trope B, Lipman TO, (2004) Vitamin supplementation: what the gastroenterologist needs to know. J Clin Gastroenterol 38: 844-854.
26. Botella-Carretero JI, Alvarez-Blasco F, Villafruela JJ, Balsa JA, Vazquez C, et al. (2007) Vitamin D deficiency is associated with the metabolic syndrome in morbid obesity. Clin Nutr 26: 573-580.
27. Adams SV, Newcomb PA, Burnett-Hartman AN, White E, Mandelson MT, et al. (2011) Circulating 25-hydroxyvitamin-D and risk of colorectal adenomas and hyperplastic polyps. Nutr Cancer 63: 319-326.
28. Fedirko V, Bostick RM, Goodman M, Flanders WD, Gross MD, (2010) Blood 25-hydroxyvitamin D3 concentrations and incident sporadic colorectal adenoma risk: a pooled case-control study. Am J Epidemiol 172: 489-500.
29. Gandini S, Boniol M, Haukka J, Byrnes G, Cox B, et al. (2011) Meta-analysis of observational studies of serum 25-hydroxyvitamin D levels and colorectal, breast and prostate cancer and colorectal adenoma. Int J Cancer 128: 1414-1424.
30. Wei MY, Garland CF, Gorham ED, Mohr SB, Giovannucci E, (2008) Vitamin D and prevention of colorectal adenoma: a meta-analysis. Cancer Epidemiol Biomarkers Prev 17: 2958-2969.
31. Roth HJ, Schmidt-Gayk H, Weber H, Niederau C, (2008) Accuracy and clinical implications of seven 25-hydroxyvitamin D methods compared with liquid chromatography-tandem mass spectrometry as a reference. Ann Clin Biochem 45: 153-159.
32. Singh RJ, Taylor RL, Reddy GS, Grebe SK, (2006) C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status. J Clin Endocrinol Metab 91: 3055-3061.
33. Howie BN, Carlson CS, Rieder MJ, Nickerson DA, (2006) Efficient selection of tagging single-nucleotide polymorphisms in multiple populations. Hum Genet 120: 58-68.
34. Lorente A, Mueller W, Urdangarin E, Lazcoz P, von Deimling A, et al. (2008) Detection of methylation in promoter sequences by melting curve analysis-based semiquantitative real time PCR. BMC Cancer 8: 61.
35. Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575.
36. Looker AC, Mussolino ME, (2008) Serum 25-hydroxyvitamin D and hip fracture risk in older U.S. white adults. J Bone Miner Res 23: 143-150.
37. Engelman CD, Fingerlin TE, Langefeld CD, Hicks PJ, Rich SS, et al. (2008) Genetic and environmental determinants of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels in Hispanic and African Americans. J Clin Endocrinol Metab 93: 3381-3388.
38. Gao L, Tao Y, Zhang L, Jin Q, (2010) Vitamin D receptor genetic polymorphisms and tuberculosis: updated systematic review and meta-analysis. Int J Tuberc Lung Dis 14: 15-23.
39. Trabert B, Malone KE, Daling JR, Doody DR, Bernstein L, et al. (2007) Vitamin D receptor polymorphisms and breast cancer risk in a large population-based case-control study of Caucasian and African-American women. Breast Cancer Res 9: R84.
40. Lee JE, Li H, Chan AT, Hollis BW, Lee IM, et al. (2011) Circulating levels of vitamin D and colon and rectal cancer: the Physicians' Health Study and a meta-analysis of prospective studies. Cancer Prev Res (Phila) 4: 735-743.
41. Touvier M, Chan DS, Lau R, Aune D, Vieira R, et al. (2011) Meta-analyses of vitamin D intake, 25-hydroxyvitamin D status, vitamin D receptor polymorphisms, and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 20: 1003-1016.
42. Ashktorab H, Nouraie M, Hosseinkhah F, Lee E, Rotimi C, et al. (2009) A 50-year review of colorectal cancer in African Americans: implications for prevention and treatment. Dig Dis Sci 54: 1985-1990.
43. Ashktorab H, Smoot DT, Carethers JM, Rahmanian M, Kittles R, et al. (2003) High incidence of microsatellite instability in colorectal cancer from African Americans. Clin Cancer Res 9: 1112-1117.
44. Nouraie M, Hosseinkhah F, Brim H, Zamanifekri B, Smoot DT, et al. (2010) Clinicopathological features of colon polyps from African-Americans. Dig Dis Sci 55: 1442-1449.
45. Houghton LA, Vieth R, (2006) The case against ergocalciferol (vitamin D2) as a vitamin supplement. Am J Clin Nutr 84: 694-697.