Endothelial nanoparticle binding kinetics are matrix and size dependent

Biotechnology and Bioengineering

Volumn 108, Issue 12, 2011, Pages 2988-2998

  Doiron, Amber L ^a,b,c   Clark, Brendan ^a   Rinker, Kristina D ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c FOOTHILLS HOSPITAL   (Canada)

Author keywords

3D cell culture; Collagen; Compliance; Dextran; HUVEC; Nanotoxicity; Polystyrene nanoparticle uptake

Indexed keywords

3-D CELL CULTURE; COMPLIANCE; HUVEC; NANOTOXICITY; POLYSTYRENE NANOPARTICLE UPTAKE;

ANIMAL CELL CULTURE; BINDING SITES; COLLAGEN; DRUG DELIVERY; ENDOTHELIAL CELLS; MEDICAL IMAGING; MOLECULAR BIOLOGY; POLYSTYRENES; SURFACE CHEMISTRY; THREE DIMENSIONAL;

NANOPARTICLES;

COLLAGEN; NANOPARTICLE;

ARTICLE; BINDING KINETICS; CELL ADHESION; CELL CULTURE; CELL GROWTH; CELL INTERACTION; ENDOCYTOSIS; HUMAN; HUMAN CELL; HYDROGEL; INTERNALIZATION; PARTICLE SIZE; SURFACE PROPERTY; UMBILICAL VEIN ENDOTHELIAL CELL;

CELLS, CULTURED; DRUG CARRIERS; ENDOTHELIAL CELLS; FLUORESCENT DYES; HUMANS; KINETICS; NANOPARTICLES; STAINING AND LABELING; TEMPERATURE;

EID: 80054036965     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.23253     Document Type: Article

References (25)

1. Albrecht DR, Underhill GH, Wassermann TB, Sah RL, Bhatia SN. 2006. Probing the role of multicellular organization in three-dimensional microenvironments. Nat Methods 3: 369-375.
2. Bhatia SN, Balis UJ, Yarmush ML, Toner M. 1998. Microfabrication of hepatocyte/fibroblast co-cultures: Role of homotypic cell interactions. Biotechnol Prog 14: 378-387.
3. Blackman BR, Barbee KA, Thibault LE. 2000. In vitro cell shearing device to investigate the dynamic response of cells in a controlled hydrodynamic environment. Ann Biomed Eng 28: 363-372.
4. Byfield FJ, Reen RK, Shentu TP, Levitan I, Gooch KJ. 2009. Endothelial actin and cell stiffness is modulated by substrate stiffness in 2D and 3D. J Biomech 42: 1114-1119.
5. Caldorera-Moore M, Guimard N, Shi L, Roy K. 2010. Designer nanoparticles: Incorporating size, shape and triggered release into nanoscale drug carriers. Expert Opin Drug Delivery 7: 479-495.
6. Chesler NC, Enyinna OC. 2003. Particle deposition in arteries ex vivo: Effects of pressure, flow, and waveform. J Biomech Eng 125: 389.
7. Clift MJ, Rothen-Rutishauser B, Brown DM, Duffin R, Donaldson K, Proudfoot L, Guy K, Stone V. 2008. The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line. Toxicol Appl Pharmacol 232: 418-427.
8. Cukierman E, Pankov R, Stevens DR, Yamada KM. 2001. Taking cell-matrix adhesions to the third dimension. Science 294: 1708-1712.
9. Davda J, Labhasetwar V. 2002. Characterization of nanoparticle uptake by endothelial cells. Int J Pharm 233: 51-59.
10. Godbey WT, Wu KK, Mikos AG. 1999. Tracking the intracellular path of poly (ethylenimine)/DNA complexes for gene delivery. Proc Natl Acad Sci USA 96: 5177-5181.
11. Goldman J, Le TX Skobe M, Swartz MA. 2005. Overexpression of VEGF-C causes transient lymphatic hyperplasia but not increased lymphangiogenesis in regenerating skin. Circ Res 96: 1193-1199.
12. Goodman TT, Chen J, Matveev K, Pun SH. 2008. Spatio-temporal modeling of nanoparticle delivery to multicellular tumor spheroids. Biotechnol Bioeng 101: 388-399.
13. Griffith L, Swartz M. 2006. Capturing complex 3D tissue physiology in vitro. Nat Rev Mol Cell Biol 7: 211-224.
14. Heldin C, Rubin K, Pietras K, Ostman A. 2004. High interstitial fluid pressure - An obstacle in cancer therapy. Nat Rev Cancer 4: 806-813.
15. Löhbach C, Neumann D, Lehr C, Lamprecht A. 2006. Human vascular endothelial cells in primary cell culture for the evaluation of nanoparticle bioadhesion. J Nanosci Nanotechnol 6: 3303-3309.
16. Matlin KS, Reggio H, Helenius A, Simons K. 1982. Pathway of vesicular stomatitis virus entry leading to infection. J Mol Biol 156: 609-631.
17. Morose G. 2010. The 5 principles of "design for safer nanotechnology". J Cleaner Prod 18: 285-289.
18. Ng CP, Pun SH. 2008. A perfusable 3D cell-matrix tissue culture chamber for in situ evaluation of nanoparticle vehicle penetration and transport. Biotechnol Bioeng 99: 1490-1501.
19. Panyam J, Sahoo S, Prabha S, Bargar T, Labhasetwar V. 2003. Fluorescence and electron microscopy probes for cellular and tissue uptake of poly(D, L-lactide-co-glycolide) nanoparticles. Int J Pharm 262: 1-11.
20. Rejman J, Oberle V, Zuhorn IS, Hoekstra D. 2004. Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis. Biochem J 377: 159-169.
21. Rinker KD, Prabhakar V, Truskey GA. 2001. Effect of contact time and force on monocyte adhesion to vascular endothelium. Biophys J 80: 1722-1732.
22. Rouleau L, Rossi J, Leask RL. 2010. Concentration and time effects of dextran exposure on endothelial cell viability, attachment, and inflammatory marker expression in vitro. Ann Biomed Eng 38: 1451-1462.
23. Sergeeva A, Kolonin MG, Molldrem JJ, Pasqualini R, Arap W. 2006. Display technologies: Application for the discovery of drug and gene delivery agents. Adv Drug Delivery Rev 58: 1622-1654.
24. Singh R, Lillard JW Jr. 2009. Nanoparticle-based targeted drug delivery. Exp Mol Pathol 86: 215-223.
25. Wilhelm C, Gazeau F, Roger J, Pons JN, Bacri J. 2002. Interaction of anionic superparamagnetic nanoparticles with cells: Kinetic analyses of membrane adsorption and subsequent internalization. Langmuir 18: 8148-8155.