Reticular angiomatoid "malignant" fibrous histiocytoma-a case report with cytogenetics and molecular genetic analyses

Human Pathology

Volumn 42, Issue 9, 2011, Pages 1359-1363

  Moura, Rafael D ^a   Wang, Xiaoke ^b   Lonzo, Melissa L ^b   Erickson Johnson, Michele R ^b   García, Joaquín J ^b   Oliveira, Andre M ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b MAYO CLINIC   (United States)

Author keywords

Angiomatoid "malignant" fibrous histiocytoma; CREB1; EWSR1; Mediastinum

Indexed keywords

DESMIN; EPITHELIAL MEMBRANE ANTIGEN; CALMODULIN BINDING PROTEIN; CREB1 PROTEIN, HUMAN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EWSR1 PROTEIN, HUMAN; ONCOPROTEIN; RNA BINDING PROTEIN;

AGED; ARTICLE; CASE REPORT; CHROMOSOME ANALYSIS; CHROMOSOME TRANSLOCATION; CREB1 GENE; CYTOGENETICS; EWSR1 GENE; FUSION GENE; GENE LOCUS; GENE REARRANGEMENT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; MALE; MALIGNANT FIBROUS HISTIOCYTOMA; MOLECULAR GENETICS; CHROMOSOME 2; CHROMOSOME 22; GENE TRANSLOCATION; GENETICS; MEDIASTINUM TUMOR; PATHOLOGY;

AGED, 80 AND OVER; CALMODULIN-BINDING PROTEINS; CHROMOSOMES, HUMAN, PAIR 2; CHROMOSOMES, HUMAN, PAIR 22; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYTOGENETIC ANALYSIS; HISTIOCYTOMA, MALIGNANT FIBROUS; HUMANS; MALE; MEDIASTINAL NEOPLASMS; ONCOGENE PROTEINS, FUSION; RNA-BINDING PROTEINS; TRANSLOCATION, GENETIC;

EID: 80054022785     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2010.12.003     Document Type: Article

References (15)

1. Fletcher CDM, Unni KK, Mertens F. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IARC Press; 2002.
2. Enzinger FM. Angiomatoid malignant fibrous histiocytoma: A distinct fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm. Cancer 1979;44:2147-57. (Pubitemid 10210845)
3. Matsumura T, Yamaguchi T, Tochigi N, Wada T, Yamashita T, Hasegawa T. Angiomatoid fibrous histiocytoma including cases with pleomorphic features analysed by fluorescence in situ hybridisation. J Clin Pathol 2010;63:124-8.
4. Fanburg-Smith JC, Miettinen M. Angiomatoid qmalignantq fibrous histiocytoma: A clinicopathologic study of 158 cases and further exploration of the myoid phenotype. HUM PATHOL 1999;30:1336-43. (Pubitemid 29534296)
5. Weiss SW, Goldblum Jr. Enzinger and Weiss's Soft Tissue Tumors. 5th ed. Philadelphia: Elsevier; 2008.
6. Costa MJ, Weiss SW. Angiomatoid malignant fibrous histiocytoma. A follow-up study of 108 cases with evaluation of possible histologic predictors of outcome. Am J Surg Pathol 1990;14:1126-32.
7. Tanas MR, Rubin BP, Montgomery EA, et al. Utility of FISH in the diagnosis of angiomatoid fibrous histiocytoma: A series of 18 cases. Mod Pathol 2010;23:93-7.
8. Mangham DC, Williams A, Lalam RK, Brundler MA, Leahy MG, Cool WP. Angiomatoid fibrous histiocytoma of bone: A calcifying sclerosing variant mimicking osteosarcoma. Am J Surg Pathol 2010;34:279-85.
9. Ren L, Guo SP, Zhou XG, Chan JK. Angiomatoid fibrous histiocytoma: First report of primary pulmonary origin. Am J Surg Pathol 2009;33:1570-4.
10. Shaffer LG, Slovak ML, Campbell LJ. ISCN 2009. An international System for Human Cytogenetic Nomenclature (2009): Recommendations of the International Standing Committee on Human Cytogenetic Nomenclature. Basel: S Karger Publishers Inc; 2009.
11. Erickson-Johnson MR, Seys AR, Roth CW, et al. Carboxypeptidase M: A biomarker for the discrimination of well-differentiated liposarcoma from lipoma. Mod Pathol 2009;22:1541-7.
12. Antonescu CR, Dal CP, Nafa K, et al. EWSR1-CREB1 is the predominant gene fusion in angiomatoid fibrous histiocytoma. Genes Chromosomes Cancer 2007;46:1051-60. (Pubitemid 47614539)
13. Dunham C, Hussong J, Seiff M, Pfeifer J, Perry A. Primary intracerebral angiomatoid fibrous histiocytoma: Report of a case with a t(12;22)(q13;q12) causing type 1 fusion of the EWS and ATF-1 genes. Am J Surg Pathol 2008;32:478-84. (Pubitemid 351398942)
14. Asakura S, Tezuka N, Inoue S, Kihara N, Fujino S. Angiomatoid fibrous histiocytoma in mediastinum. Ann Thorac Surg 2001;72:283-5. (Pubitemid 32643066)
15. Davies KA, Cope AP, Schofield JB, et al. A rare mediastinal tumour presenting with systemic effects due to IL-6 and tumour necrosis factor (TNF) production. Clin Exp Immunol 1995;99:117-23.