Achieving donor management goals before deceased donor procurement is associated with more organs transplanted per donor

Journal of Trauma - Injury, Infection and Critical Care

Volumn 71, Issue 4, 2011, Pages 990-995

  Malinoski, Darren J ^a   Daly, Michael C ^b   Patel, Madhukar S ^b   Oley Graybill, Chrystal ^c   Foster, Clarence E ^b   Salim, Ali ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNITED NETWORK FOR ORGAN SHARING   (United States)

Author keywords

Checklist; Donor management; Donor management goals; Organ donation; Transplantation

Indexed keywords

CREATININE; DOPAMINE; GLUCOSE; HEMOGLOBIN; INSULIN; NORADRENALIN; OXYGEN; PHENYLEPHRINE; SODIUM; STEROID; THYROID HORMONE; VASOPRESSIN;

ADULT; AGE; ARTICLE; BLOOD OXYGEN TENSION; CADAVER DONOR; CENTRAL VENOUS PRESSURE; CREATININE BLOOD LEVEL; DONOR MANAGEMENT GOAL; GLUCOSE BLOOD LEVEL; GOAL ATTAINMENT; HEALTH CARE ORGANIZATION; HEART EJECTION FRACTION; HEMOGLOBIN BLOOD LEVEL; HORMONAL THERAPY; HUMAN; INSULIN TREATMENT; LOW DRUG DOSE; MEAN ARTERIAL PRESSURE; ORGAN DONOR; ORGAN TRANSPLANTATION; OUTCOME ASSESSMENT; PREDICTIVE VALUE; PRIORITY JOURNAL; SODIUM BLOOD LEVEL; STEROID THERAPY; URINE VOLUME;

ADULT; BRAIN DEATH; FEMALE; HUMANS; LOGISTIC MODELS; MALE; ORGANIZATIONAL OBJECTIVES; RETROSPECTIVE STUDIES; TISSUE AND ORGAN PROCUREMENT; TISSUE DONORS; UNITED STATES;

EID: 80054015939     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e31822779e5     Document Type: Article

References (26)

1. 2007 Annual Report of the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients: Transplant Data 1997-2006. Department of Health and Human Services, Health Resources and Services Administration, Healthcare Systems Bureau, Division of Transplantation, Rockville, MD; United Network for Organ Sharing, Richmond, VA; University Renal Research and Education Association, Ann Arbor, MI.
2. Mackersie RC, Bronsther OL, Shackford SR. Organ procurement in patients with fatal head injuries. The fate of the potential donor. Ann Surg. 1991;213:143-150.
3. Wheeldon DR, Potter CD, Oduro A, Wallwork J, Large SR. Transforming the "unacceptable" donor: Outcomes from the adoption of a standardized donor management technique. J Heart Lung Transplant. 1995; 14:734-742.
4. Rosendale JD, Kauffman HM, McBride MA, et al. Hormonal resuscitation yields more transplanted hearts, with improved early function. Transplantation. 2003;75:1336-1341. (Pubitemid 36513044)
5. Zaroff JG, Rosengard BR, Armstrong WF, et al. Consensus conference report: Maximizing use of organs recovered from the cadaver donor: Cardiac recommendations, March 28-29, 2001, Crystal City, VA. Circulation. 2002;106:836-841.
6. Venkateswaran RV, Steeds RP, Quinn DW, et al. The haemodynamic effects of adjunctive hormone therapy in potential heart donors: A prospective randomized double-blind factorially designed controlled trial. Eur Heart J. 2009;30:1771-1780.
7. Venkateswaran RV, Patchell VB, Wilson IC, et al. Early donor management increases the retrieval rate of lungs for transplantation. Ann Thorac Surg. 2008;85:278-286; discussion 286. (Pubitemid 350265819)
8. Follette DM, Rudich SM, Babcock WD. Improved oxygenation and increased lung donor recovery with high-dose steroid administration after brain death. J Heart Lung Transplant. 1998;17:423-429. (Pubitemid 28196962)
9. Straznicka M, Follette DM, Eisner MD, Roberts PF, Menza RL, Babcock WD. Aggressive management of lung donors classified as unacceptable: Excellent recipient survival one year after transplantation. J Thorac Cardiovasc Surg. 2002;124:250-258. (Pubitemid 35025600)
10. Shemie SD, Ross H, Pagliarello J, et al. Organ donor management in Canada: Recommendations of the forum on Medical Management to Optimize Donor Organ Potential. CMAJ. 2006;174:S13-S32.
11. United Network for Organ Sharing-Clinical Pathway for the Organ Donor. 2002, 2001, 1998. Available at: Http://www.unos.org/donation/index.php?topic- best-practices. Accessed May 6, 2011.
12. Hagan ME, McClean D, Falcone CA, Arrington J, Matthews D, Summe C. Attaining specific donor management goals increases number of organs transplanted per donor: A quality improvement project. Prog Transplant. 2009;19:227-231.
13. Franklin GA, Santos AP, Smith JW, Galbraith S, Harbrecht BG, Garrison RN. Optimization of donor management goals yields increased organ use. Am Surg. 2010;76:587-594.
14. Hunt SA, Baldwin J, Baumgartner W, et al. Cardiovascular management of a potential heart donor: A statement from the Transplantation Committee of the American College of Cardiology. Crit Care Med. 1996; 24:1599-1601. (Pubitemid 26313765)
15. Pennefather SH, Bullock RE, Dark JH. The effect of fluid therapy on alveolar arterial oxygen gradient in brain-dead organ donors. Transplantation. 1993;56:1418-1422. (Pubitemid 24018798)
16. Gabbay E, Williams TJ, Griffiths AP, et al. Maximizing the utilization of donor organs offered for lung transplantation. Am J Respir Crit Care Med. 1999;160:265-271. (Pubitemid 29326098)
17. Sundaresan S, Semenkovich J, Ochoa L, et al. Successful outcome of lung transplantation is not compromised by the use of marginal donor lungs. J Thorac Cardiovasc Surg. 1995;109:1075-1079; discussion 1079-1080.
18. Kutsogiannis DJ, Pagliarello G, Doig C, Ross H, Shemie SD. Medical management to optimize donor organ potential: Review of the literature. Can J Anaesth. 2006;53:820-830. (Pubitemid 44424229)
19. Port FK, Bragg-Gresham JL, Metzger RA, et al. Donor characteristics associated with reduced graft survival: An approach to expanding the pool of kidney donors. Transplantation. 2002;74:1281-1286. (Pubitemid 35402598)
20. Rosendale JD, Kauffman HM, McBride MA, et al. Aggressive pharmacologic donor management results in more transplanted organs. Transplantation. 2003;75:482-487. (Pubitemid 36241143)
21. Helmreich RL. On error management: Lessons from aviation. BMJ. 2000;320:781-785. (Pubitemid 30179433)
22. Gawande A. The checklist: If something so simple can transform intensive care, what else can it do? New Yorker. 2007:86-101.
23. DuBose JJ, Inaba K, Shiflett A, et al. Measurable outcomes of quality improvement in the trauma intensive care unit: The impact of a daily quality rounding checklist. J Trauma. 2008;64:22-27; discussion 27-29.
24. Haynes AB, Weiser TG, Berry WR, et al. A surgical safety checklist to reduce morbidity and mortality in a global population. N Engl J Med. 2009;360:491-499.
25. Young GB, Frewen T, Barr HW, et al. Checklist for diagnosis of brain death. Can J Neurol Sci. 1991;18:104.
26. Hall RI, Rocker GM, Murray D. Simple changes can improve conduct of end-of-life care in the intensive care unit. Can J Anaesth. 2004;51:631-636. (Pubitemid 38877550)