A minimalist model for ion partitioning and competition in a K + channel selectivity filter

Journal of General Physiology

Volumn 138, Issue 3, 2011, Pages 371-373

  Kast, Stefan M ^a   Kloss, Thomas ^b   Tayefeh, Sascha ^c   Thiel, Gerhard ^c  

^a TU DORTMUND UNIVERSITY   (Germany)

^b UNIVERSITÉ JOSEPH FOURIER   (France)

^c DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM; POTASSIUM CHANNEL; SODIUM;

ARTICLE; BIOLOGICAL MODEL; CHANNEL GATING; CHEMISTRY; METABOLISM;

ION CHANNEL GATING; MODELS, BIOLOGICAL; POTASSIUM; POTASSIUM CHANNELS; SODIUM;

EID: 80054006520     PISSN: 00221295     EISSN: 15407748     Source Type: Journal    
DOI: 10.1085/jgp.201110694     Document Type: Article

References (15)

1. Alam, A., and Y. Jiang. 2011. Structural studies of ion selectivity in tetrameric cation channels. J. Gen. Physiol. 137:397-403. doi:10.1085/jgp.201010546
2. Andersen, O.S. 2011. Perspectives on: Ion selectivity. J. Gen. Physiol. 137:393-395. doi:10.1085/jgp.201110651
3. Beglov, D., and B. Roux. 1997. An integral equation to describe the solvation of polar molecules in liquid water. J. Phys. Chem. B. 101:7821-7826 doi:10.1021/jp971083h
4. + channel. Biochemistry. 37:3229-3236. doi:10.1021/bi972997x
5. + channel. J. Gen. Physiol. 137:427-433. doi:10.1085/jgp.201010533
6. Kloss, T. 2007. Quantitative Berechnung thermodynamischer Observablen mittels dreidimensionaler Integralgleichungsthe orien. PhD thesis. Technische Universität Darmstadt, Darmstadt, Germany. 108 pp.
7. Kloss, T., and S.M. Kast. 2008. Treatment of charged solutes in threedimensional integral equation theory. J. Chem. Phys. 128:134505. doi:10.1063/1.2841967
8. Kovalenko, A., and F. Hirata. 1998. Three-dimensional density profiles of water in contact with a solute of arbitrary shape: a RISM approach. Chem. Phys. Lett. 290:237-244. doi:10.1016/S0009-2614(98)00471-0
9. Meuser, D., H. Splitt, R. Wagner, and H. Schrempf. 1999. Exploring the open pore of the potassium channel from Streptomyces lividans. FEBS Lett. 462:447-452. doi:10.1016/S0014-5793(99)01579-3
10. Nimigean, C.M., and T.W. Allen. 2011. Origins of ion selectivity in potassium channels from the perspective of channel block. J. Gen. Physiol. 137:405-413. doi:10.1085/jgp.201010551
11. Roux, B., S. Bernéche, B. Egwolf, B. Lev, S.Y. Noskov, C.N. Rowley, and H. Yu. 2011. Ion selectivity in channels and transporters. J. Gen. Physiol. 137:415-426. doi:10.1085/jgp.201010577
12. Smart, O.S., J.G. Neduvelil, X. Wang, B.A. Wallace, and M.S.P. Sansom. 1996. HOLE: a program for the analysis of the pore dimensions of ion channel structural models. J. Mol. Graph. 14:354-360: 376. doi:10.1016/S0263-7855(97)00009-X
13. Tayefeh, S., T. Kloss, G. Thiel, B. Hertel, A. Moroni, and S.M. Kast. 2007. Molecular dynamics simulation of the cytosolic mouth in Kcv-type potassium channels. Biochemistry. 46:4826-4839. doi:10.1021/bi602468r
14. Varma, S., D.M. Rogers, L.R. Pratt, and S.B. Rempe. 2011. Perspectives on: Ion selectivity. Design principles for K+ selectivity in membrane transport. J. Gen. Physiol. 137:479-488. doi:10.1085/jgp.201010579
15. Zhou, Y.F., J.H. Morais-Cabral, A. Kaufman, and R. MacKinnon. 2001. Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Nature. 414:43-48. doi:10.1038/35102009