Design of prolonged release tablets using new solid acrylic excipients for direct compression

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 79, Issue 3, 2011, Pages 664-673

  Villanova, J C O ^a   Ayres, E ^b   Orefice R L ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b Universidade Estadual de Minas Gerais UEMG   (Brazil)

Author keywords

Acrylic solid excipient; Direct compression; Inert matrices; Micromeritic properties; Polymerization techniques; Tablets

Indexed keywords

ACRYLIC ACID; ACRYLIC ACID ETHYL ESTER; AEROSIL; EXCIPIENT; METHACRYLIC ACID BUTYL ESTER; METHACRYLIC ACID METHYL ESTER; POLYMER; PROPRANOLOL; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CONTACT ANGLE; CONTROLLED STUDY; CYTOTOXICITY; DELAYED DRUG RELEASE; DENSITY GRADIENT; DRUG DESIGN; DRUG RELEASE; DRUG SOLUBILITY; EMULSION; FIBROBLAST; GINGIVA; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; PARTICLE SIZE; POLYMERIZATION; POWDER; SCANNING ELECTRON MICROSCOPY; SUSPENSION; TABLET COMPRESSION; TABLET FRIABILITY; TABLET HARDNESS;

ACRYLATES; CELL LINE; CELL SURVIVAL; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; DRUG DESIGN; EXCIPIENTS; FIBROBLASTS; GINGIVA; HUMANS; METHACRYLATES; METHYLMETHACRYLATE; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES; TABLETS;

EID: 80053989046     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.07.011     Document Type: Article

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