메뉴 건너뛰기




Volumn 40, Issue 9, 2011, Pages 1200-1216

Incorporating technical risk in compound real option models to value a pharmaceutical R&D licensing opportunity

Author keywords

Case study; Compound option model; Pharmaceutical R D; Real options; Technical risk

Indexed keywords

CLOSED FORM SOLUTIONS; COMPOUND OPTION MODEL; DRUG DEVELOPMENT; EXTENDED MODEL; PHARMACEUTICAL INDUSTRY; REAL OPTION MODELS; REAL OPTIONS; RISK MEASURES; TECHNICAL RISKS; THEORETICAL MODELS;

EID: 80053988626     PISSN: 00487333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.respol.2011.05.020     Document Type: Article
Times cited : (54)

References (44)
  • 3
    • 0001662131 scopus 로고    scopus 로고
    • Justifying electronic banking network expansion using real options analysis
    • M. Benaroch, and R.J. Kauffman Justifying electronic banking network expansion using real options analysis MIS Quarterly 24 2000 197 225
    • (2000) MIS Quarterly , vol.24 , pp. 197-225
    • Benaroch, M.1    Kauffman, R.J.2
  • 4
    • 0035594305 scopus 로고    scopus 로고
    • A gene to drug venture: Poisson options analysis
    • M. Brach, and D. Paxson A gene to drug venture: poisson options analysis R&D Management 31 2001 203 214 (Pubitemid 33279316)
    • (2001) R and D Management , vol.31 , Issue.2 , pp. 203-214
    • Brach, M.A.1    Paxson, D.A.2
  • 6
    • 0347959718 scopus 로고    scopus 로고
    • Frank J. Fabozzi Associates New Hope, Pennsylvania
    • D. Chance Essays in Derivatives 1998 Frank J. Fabozzi Associates New Hope, Pennsylvania
    • (1998) Essays in Derivatives
    • Chance, D.1
  • 8
    • 34248536156 scopus 로고    scopus 로고
    • Optimal exploration investments under price and geological-technical uncertainty: A real options model
    • D. Paxson, Butterworth-Heinemann Oxford
    • G. Cortazar, E. Schwartz, and J. Casassus Optimal exploration investments under price and geological-technical uncertainty: a real options model D. Paxson, Real R&D Options 2003 Butterworth-Heinemann Oxford 149 165
    • (2003) Real R&D Options , pp. 149-165
    • Cortazar, G.1    Schwartz, E.2    Casassus, J.3
  • 10
    • 0035338343 scopus 로고    scopus 로고
    • Risks in new drug development: Approval success rates for investigational drugs
    • J. DiMasi Risks in new drug development: approval success rates for investigational drugs Clinical Pharmacology & Therapeutics 69 2001 297 307
    • (2001) Clinical Pharmacology & Therapeutics , vol.69 , pp. 297-307
    • Dimasi, J.1
  • 12
    • 0035254147 scopus 로고    scopus 로고
    • Managing uncertainty in research and development
    • DOI 10.1016/S0166-4972(00)00026-2
    • R. Doctor, D. Newton, and A. Pearson Managing uncertainty in research and development Technovation 21 2001 79 90 (Pubitemid 32030324)
    • (2001) Technovation , vol.21 , Issue.2 , pp. 79-90
    • Doctor, R.N.1    Newton, D.P.2    Pearson, A.3
  • 13
    • 60449105300 scopus 로고    scopus 로고
    • The value of a 'failed' R&D project: An emerging evaluation framework for building innovative capabilities
    • M. Elmquist, and P. Le Masson The value of a 'failed' R&D project: an emerging evaluation framework for building innovative capabilities R&D Management 39 2009 136 151
    • (2009) R&D Management , vol.39 , pp. 136-151
    • Elmquist, M.1    Le Masson, P.2
  • 14
  • 15
    • 33646058025 scopus 로고    scopus 로고
    • Application of real option analysis for pharmaceutical R&D project evaluation - Empirical results from a survey
    • M. Hartmann, and A. Hassan Application of real option analysis for pharmaceutical R&D project evaluation - empirical results from a survey Research Policy 35 2006 343 354
    • (2006) Research Policy , vol.35 , pp. 343-354
    • Hartmann, M.1    Hassan, A.2
  • 16
    • 0037399741 scopus 로고    scopus 로고
    • In search of innovative techniques to evaluate pharmaceutical R&D projects
    • W. Jacob, and Y. Kwak In search of innovative techniques to evaluate pharmaceutical R&D projects Technovation 23 2005 291 296
    • (2005) Technovation , vol.23 , pp. 291-296
    • Jacob, W.1    Kwak, Y.2
  • 17
    • 6244299430 scopus 로고    scopus 로고
    • The use of options theory to value research in the service sector
    • K. Jensen, and P. Warren The use of options theory to value research in the service sector R&D Management 31 2001 173 180 (Pubitemid 33279313)
    • (2001) R and D Management , vol.31 , Issue.2 , pp. 173-180
    • Jensen, K.1    Warren, P.2
  • 18
    • 0001954909 scopus 로고    scopus 로고
    • Real-options valuation for a biotechnology company
    • D. Kellogg, and J.M. Charnes Real-options valuation for a biotechnology company Financial Analysts Journal 56 2000 76 84
    • (2000) Financial Analysts Journal , vol.56 , pp. 76-84
    • Kellogg, D.1    Charnes, J.M.2
  • 19
    • 0035645903 scopus 로고    scopus 로고
    • Valuation of R&D real American sequential exchange options
    • J. Lee, and D. Paxson Valuation of R&D real American sequential exchange options R&D Management 31 2001 191 201 (Pubitemid 33707317)
    • (2001) R and D Management , vol.31 , Issue.2 , pp. 191-201
    • Lee, J.1    Paxson, D.A.2
  • 20
    • 0035588082 scopus 로고    scopus 로고
    • An option approach to the new product development process: A case study at Philips Electronics
    • O. Lint, and E. Pennings An option approach to the new product development process: a case study at Philips Electronics R&D Management 31 2001 163 172
    • (2001) R&D Management , vol.31 , pp. 163-172
    • Lint, O.1    Pennings, E.2
  • 21
    • 0035609496 scopus 로고    scopus 로고
    • Evaluating growth options as sources of value for pharmaceutical research projects
    • C.H. Loch, and K. Bode-Greuel Evaluating growth options as sources of value for pharmaceutical research projects R&D Management 31 2001 231 248
    • (2001) R&D Management , vol.31 , pp. 231-248
    • Loch, C.H.1    Bode-Greuel, K.2
  • 22
    • 0035578679 scopus 로고    scopus 로고
    • Valuing American options by simulation: A simple least-squares approach
    • F. Longstaff, and E. Schwartz Valuing American options by simulation: a simple least-square approach Review of Financial Studies 14 2001 113 147 (Pubitemid 33587386)
    • (2001) Review of Financial Studies , vol.14 , Issue.1 , pp. 113-147
    • Longstaff, F.A.1    Schwartz, E.S.2
  • 23
    • 0003099819 scopus 로고
    • Finance theory and financial strategy
    • S. Myers Finance theory and financial strategy Interfaces 14 1984 126 137
    • (1984) Interfaces , vol.14 , pp. 126-137
    • Myers, S.1
  • 24
    • 84982686434 scopus 로고
    • Application of option pricing theory to R&D
    • D. Newton, and A. Pearson Application of option pricing theory to R&D R&D Management 24 1994 83 89
    • (1994) R&D Management , vol.24 , pp. 83-89
    • Newton, D.1    Pearson, A.2
  • 26
    • 0002857442 scopus 로고
    • Scientific management at Merck: An interview with CFO Judy Lewent
    • N. Nicols Scientific management at Merck: an interview with CFO Judy Lewent Harvard Business Review 72 1994 89 99
    • (1994) Harvard Business Review , vol.72 , pp. 89-99
    • Nicols, N.1
  • 28
    • 8644270714 scopus 로고    scopus 로고
    • Genzyme biosurgery: A virtual real R&D option case
    • D. Paxson, Butterworth-Heinemann Oxford
    • D. Paxson Genzyme biosurgery: a virtual real R&D option case D. Paxson, Real R&D Options 2003 Butterworth-Heinemann Oxford 271 290
    • (2003) Real R&D Options , pp. 271-290
    • Paxson, D.1
  • 30
    • 0013417759 scopus 로고    scopus 로고
    • Real options valuation: The new frontier in R&D project evaluation?
    • M. Perlitz, T. Peske, and R. Schrank Real options valuation: the new frontier in R&D project evaluation? R&D Management 29 1999 255 270
    • (1999) R&D Management , vol.29 , pp. 255-270
    • Perlitz, M.1    Peske, T.2    Schrank, R.3
  • 31
    • 77953659097 scopus 로고    scopus 로고
    • When failure should be the option
    • G. Petsko When failure should be the option BMC Biology 8 2010 61 63
    • (2010) BMC Biology , vol.8 , pp. 61-63
    • Petsko, G.1
  • 33
    • 2942605728 scopus 로고    scopus 로고
    • Patents and R&D as real options
    • E. Schwartz Patents and R&D as real options Economic Notes 33 2004 23 54
    • (2004) Economic Notes , vol.33 , pp. 23-54
    • Schwartz, E.1
  • 35
    • 0002410475 scopus 로고    scopus 로고
    • Evaluating research and development investments
    • M. Brennan, L. Trigeorgis, Oxford University Press New York
    • E. Schwartz, and M. Moon Evaluating research and development investments M. Brennan, L. Trigeorgis, Project Flexibility, Agency, and Competition 2000 Oxford University Press New York 85 106
    • (2000) Project Flexibility, Agency, and Competition , pp. 85-106
    • Schwartz, E.1    Moon, M.2
  • 36
    • 2942607930 scopus 로고    scopus 로고
    • Rational pricing of Internet companies revisited
    • E. Schwartz, and M. Moon Rational pricing of Internet companies revisited The Financial Review 36 2001 7 26
    • (2001) The Financial Review , vol.36 , pp. 7-26
    • Schwartz, E.1    Moon, M.2
  • 37
    • 0037284628 scopus 로고    scopus 로고
    • Investment under uncertainty in information technology: Acquisition and development projects
    • E. Schwartz, and C. Zozaya-Gorostiza Investment under uncertainty in information technology: acquisition and development projects Management Science 49 2003 57 70
    • (2003) Management Science , vol.49 , pp. 57-70
    • Schwartz, E.1    Zozaya-Gorostiza, C.2
  • 38
    • 0032015175 scopus 로고    scopus 로고
    • How SmithKline Beecham makes better resource-allocation decisions
    • P. Sharpe, and T. Keelin How SmithKline Beecham makes better resource-allocation decisions Harvard Business Review 76 1998 45 57
    • (1998) Harvard Business Review , vol.76 , pp. 45-57
    • Sharpe, P.1    Keelin, T.2
  • 42
    • 33846815398 scopus 로고    scopus 로고
    • Repositioning's role in drug discovery and development
    • L. Tartaglia, and L. Babiss Repositioning's role in drug discovery and development Drug Discovery World 7 2006 9 15
    • (2006) Drug Discovery World , vol.7 , pp. 9-15
    • Tartaglia, L.1    Babiss, L.2
  • 44
    • 54349106187 scopus 로고    scopus 로고
    • Project valuation in the pharmaceutical industry: A comparison of least-squares Monte Carlo real option valuation and conventional approaches
    • B. Willigers, and J. Hansen Project valuation in the pharmaceutical industry: a comparison of least-squares Monte Carlo real option valuation and conventional approaches R&D Management 38 2008 520 537
    • (2008) R&D Management , vol.38 , pp. 520-537
    • Willigers, B.1    Hansen, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.