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Volumn 9, Issue 10, 2011, Pages 1186-1196

Evolving paradigms in the treatment of newly diagnosed multiple myeloma

Author keywords

Consolidation; Induction; Maintenance; Multiple myeloma; New drugs

Indexed keywords

BORTEZOMIB; CISPLATIN; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; LENALIDOMIDE; MELPHALAN; PREDNISONE; THALIDOMIDE; VINCRISTINE;

EID: 80053980100     PISSN: 15401405     EISSN: 15401413     Source Type: Journal    
DOI: 10.6004/jnccn.2011.0096     Document Type: Review
Times cited : (8)

References (61)
  • 2
    • 41949114641 scopus 로고    scopus 로고
    • Recent major improvement in long-term survival of younger patients with multiple myeloma
    • Brenner H, Gondos A, Pulte D. Recent major improvement in long-term survival of younger patients with multiple myeloma. Blood 2008;111:2521-2526.
    • (2008) Blood , vol.111 , pp. 2521-2526
    • Brenner, H.1    Gondos, A.2    Pulte, D.3
  • 3
    • 41949130070 scopus 로고    scopus 로고
    • Improved survival in multiple myeloma and the impact of novel therapies
    • Kumar SK, Rajkumar SV, Dispenzieri A, et al. Improved survival in multiple myeloma and the impact of novel therapies. Blood 2008;111:2516-2520.
    • (2008) Blood , vol.111 , pp. 2516-2520
    • Kumar, S.K.1    Rajkumar, S.V.2    Dispenzieri, A.3
  • 5
    • 58249097191 scopus 로고    scopus 로고
    • Criteria for diagnosis, staging, risk stratification and response assessment of multiple myeloma
    • Kyle RA, Rajkumar SV. Criteria for diagnosis, staging, risk stratification and response assessment of multiple myeloma. Leukemia 2009;23:3-9.
    • (2009) Leukemia , vol.23 , pp. 3-9
    • Kyle, R.A.1    Rajkumar, S.V.2
  • 7
    • 77954610729 scopus 로고    scopus 로고
    • Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management
    • Kyle RA, Durie BG, Rajkumar SV, et al. Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management. Leukemia 2010;24:1121-1127.
    • (2010) Leukemia , vol.24 , pp. 1121-1127
    • Kyle, R.A.1    Durie, B.G.2    Rajkumar, S.V.3
  • 8
    • 20644460600 scopus 로고    scopus 로고
    • International staging system for multiple myeloma
    • Greipp PR, San Miguel J, Durie BG, et al. International staging system for multiple myeloma. J Clin Oncol 2005;23:3412-3420.
    • (2005) J Clin Oncol , vol.23 , pp. 3412-3420
    • Greipp, P.R.1    San Miguel, J.2    Durie, B.G.3
  • 13
    • 73349126431 scopus 로고    scopus 로고
    • Achievement of at least very good partial response is a simple and robust prognostic factor in patients with multiple myeloma treated with high-dose therapy: Long-term analysis of the IFM 99-02 and 99-04 Trials
    • Harousseau JL, Avet-Loiseau H, Attal M, et al. Achievement of at least very good partial response is a simple and robust prognostic factor in patients with multiple myeloma treated with high-dose therapy: long-term analysis of the IFM 99-02 and 99-04 Trials. J Clin Oncol 2009;27:5720-5726.
    • (2009) J Clin Oncol , vol.27 , pp. 5720-5726
    • Harousseau, J.L.1    Avet-Loiseau, H.2    Attal, M.3
  • 14
    • 79953078844 scopus 로고    scopus 로고
    • Complete response correlates with long-term progression-free and overall survivals in elderly myeloma treated with novel agents: Analysis of 1175 patients
    • Gay F, Larocca A, Wijermans P, et al. Complete response correlates with long-term progression-free and overall survivals in elderly myeloma treated with novel agents: analysis of 1175 patients. Blood 2011;117:3025-3031.
    • (2011) Blood , vol.117 , pp. 3025-3031
    • Gay, F.1    Larocca, A.2    Wijermans, P.3
  • 15
    • 79955048912 scopus 로고    scopus 로고
    • Comparison of immunofixation, serum free light chain, and immunophenotyping for response evaluation and prognostication in multiple myeloma
    • Paiva B, Martinez-Lopez J, Vidriales MB, et al. Comparison of immunofixation, serum free light chain, and immunophenotyping for response evaluation and prognostication in multiple myeloma. J Clin Oncol 2011;29:1627-1633.
    • (2011) J Clin Oncol , vol.29 , pp. 1627-1633
    • Paiva, B.1    Martinez-Lopez, J.2    Vidriales, M.B.3
  • 18
    • 0025064260 scopus 로고
    • VAD-based regimens as primary treatment for multiple myeloma
    • DOI 10.1002/ajh.2830330203
    • Alexanian R, Barlogie B, Tucker S. VAD-based regimens as primary treatment for multiple myeloma. Am J Hematol 1990;33:86-89. (Pubitemid 20040083)
    • (1990) American Journal of Hematology , vol.33 , Issue.2 , pp. 86-89
    • Alexanian, R.1    Barlogie, B.2    Tucker, S.3
  • 19
    • 43749117945 scopus 로고    scopus 로고
    • A multicenter, randomized, double-blind, placebo-controlled study of thalidomide plus dexamethasone versus dexamethasone as initial therapy for newly diagnosed multiple myeloma
    • Rajkumar SV, Rosiñol L, Hussein M, et al. A multicenter, randomized, double-blind, placebo-controlled study of thalidomide plus dexamethasone versus dexamethasone as initial therapy for newly diagnosed multiple myeloma. J Clin Oncol 2008;26:2171-2177.
    • (2008) J Clin Oncol , vol.26 , pp. 2171-2177
    • Rajkumar, S.V.1    Rosiñol, L.2    Hussein, M.3
  • 20
    • 78649686431 scopus 로고    scopus 로고
    • Lenalidomide and high-dose dexamethasone compared with dexamethasone as initial therapy for multiple myeloma: A randomized Southwest Oncology Group trial (S0232)
    • Zonder JA, Crowley J, Hussein MA, et al. Lenalidomide and high-dose dexamethasone compared with dexamethasone as initial therapy for multiple myeloma: a randomized Southwest Oncology Group trial (S0232). Blood 2010;116:5838-5841.
    • (2010) Blood , vol.116 , pp. 5838-5841
    • Zonder, J.A.1    Crowley, J.2    Hussein, M.A.3
  • 21
    • 73249146496 scopus 로고    scopus 로고
    • Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: An open-label randomised controlled trial
    • Rajkumar SV, Jacobus S, Callander NS, et al. Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial. Lancet Oncol 2010;11:29-37.
    • (2010) Lancet Oncol , vol.11 , pp. 29-37
    • Rajkumar, S.V.1    Jacobus, S.2    Callander, N.S.3
  • 24
    • 78049488759 scopus 로고    scopus 로고
    • Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: Results of the IFM 2005-01 phase III trial
    • Harousseau JL, Attal M, Avet-Loiseau H, et al. Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: results of the IFM 2005-01 phase III trial. J Clin Oncol 2010;28:4621-4629.
    • (2010) J Clin Oncol , vol.28 , pp. 4621-4629
    • Harousseau, J.L.1    Attal, M.2    Avet-Loiseau, H.3
  • 27
    • 77649092410 scopus 로고    scopus 로고
    • Phase II trial of combination therapy with bortezomib, pegylated liposomal doxorubicin, and dexamethasone in patients with newly diagnosed myeloma
    • Jakubowiak AJ, Kendall T, Al-Zoubi A, et al. Phase II trial of combination therapy with bortezomib, pegylated liposomal doxorubicin, and dexamethasone in patients with newly diagnosed myeloma. J Clin Oncol 2009;27:5015-5022.
    • (2009) J Clin Oncol , vol.27 , pp. 5015-5022
    • Jakubowiak, A.J.1    Kendall, T.2    Al-Zoubi, A.3
  • 28
    • 78650303860 scopus 로고    scopus 로고
    • Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: A randomised phase 3 study
    • Cavo M, Tacchetti P, Patriarca F, et al. Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study. Lancet 2010;376:2075-2085.
    • (2010) Lancet , vol.376 , pp. 2075-2085
    • Cavo, M.1    Tacchetti, P.2    Patriarca, F.3
  • 29
    • 77952295503 scopus 로고    scopus 로고
    • Thalidomide/dexamethasone (TD) vs. bortezomib (velcade)/thalidomide/ dexamethasone (VTD) vs. VBMCP/VBAD/velcade as induction regimens prior autologous stem cell transplantation (ASCT) in multiple myeloma (MM): Results of a phase III PETHEMA/GEM trial
    • [abstract]. Abstract 130
    • Rosiñol L, Cibeira MA, Martinez J, et al. Thalidomide/dexamethasone (TD) vs. bortezomib (velcade)/thalidomide/dexamethasone (VTD) vs. VBMCP/VBAD/velcade as induction regimens prior autologous stem cell transplantation (ASCT) in multiple myeloma (MM): results of a phase III PETHEMA/GEM trial [abstract]. Blood 2009;114:Abstract 130.
    • (2009) Blood , vol.114
    • Rosiñol, L.1    Cibeira, M.A.2    Martinez, J.3
  • 30
    • 79952721748 scopus 로고    scopus 로고
    • Comparison of reduced-dose bortezomib plus thalidomide plus dexamethasone (vTD) to bortezomib plus dexamethasone (VD) as induction treatment prior to ASCT in de novo multiple myeloma (MM): Results of IFM2007-02 study
    • [abstract]. Abstract 8014
    • Moreau P, Facon T, Attal M, et al. Comparison of reduced-dose bortezomib plus thalidomide plus dexamethasone (vTD) to bortezomib plus dexamethasone (VD) as induction treatment prior to ASCT in de novo multiple myeloma (MM): results of IFM2007-02 study [abstract]. J Clin Oncol 2010;28:Abstract 8014.
    • (2010) J Clin Oncol , vol.28
    • Moreau, P.1    Facon, T.2    Attal, M.3
  • 31
    • 77954618168 scopus 로고    scopus 로고
    • Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
    • Richardson PG, Weller E, Lonial S, et al. Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma. Blood 2010;116:679-686.
    • (2010) Blood , vol.116 , pp. 679-686
    • Richardson, P.G.1    Weller, E.2    Lonial, S.3
  • 32
    • 79955579707 scopus 로고    scopus 로고
    • Bortezomib, IV cyclophosphamide, and dexamethasone (VelCD) as induction in newly diagnosed multiple myeloma: Results of an interim analysis of the German DSMM Xia trial
    • [abstract]. Abstract 8516
    • Knop S, Liebisch P, Wandt H, et al. Bortezomib, IV cyclophosphamide, and dexamethasone (VelCD) as induction in newly diagnosed multiple myeloma: results of an interim analysis of the German DSMM Xia trial [abstract]. J Clin Oncol 2009;27:Abstract 8516.
    • (2009) J Clin Oncol , vol.27
    • Knop, S.1    Liebisch, P.2    Wandt, H.3
  • 33
    • 80051557449 scopus 로고    scopus 로고
    • Cyclophosphamide, thalidomide, and dexamethasone (CTD) as initial therapy for patients with multiple myeloma unsuitable for autologous transplantation
    • Morgan GJ, Davies FE, Gregory WM, et al. Cyclophosphamide, thalidomide, and dexamethasone (CTD) as initial therapy for patients with multiple myeloma unsuitable for autologous transplantation. Blood 2011;118:1231-1238.
    • (2011) Blood , vol.118 , pp. 1231-1238
    • Morgan, G.J.1    Davies, F.E.2    Gregory, W.M.3
  • 34
    • 77954660886 scopus 로고    scopus 로고
    • Bortezomib, dexamethasone, cyclophosphamide and lenalidomide combination for newly diagnosed multiple myeloma: Phase 1 results from the multicenter EVOLUTION study
    • Kumar SK, Flinn I, Noga SJ, et al. Bortezomib, dexamethasone, cyclophosphamide and lenalidomide combination for newly diagnosed multiple myeloma: phase 1 results from the multicenter EVOLUTION study. Leukemia 2010;24:1350-1356.
    • (2010) Leukemia , vol.24 , pp. 1350-1356
    • Kumar, S.K.1    Flinn, I.2    Noga, S.J.3
  • 35
    • 79952834761 scopus 로고    scopus 로고
    • Phase III intergroup study of lenalidomide versus placebo maintenance therapy following single autologous hematopoietic stem cell transplantation (AHSCT) for multiple myeloma: CALGB 100104
    • [abstract]. Abstract 37
    • McCarthy PL, Owzar K, Anderson KC, et al. Phase III intergroup study of lenalidomide versus placebo maintenance therapy following single autologous hematopoietic stem cell transplantation (AHSCT) for multiple myeloma: CALGB 100104 [abstract]. Blood 2010;116:Abstract 37.
    • (2010) Blood , vol.116
    • McCarthy, P.L.1    Owzar, K.2    Anderson, K.C.3
  • 36
    • 79952836604 scopus 로고    scopus 로고
    • Maintenance treatment with lenalidomide after transplantation for MYELOMA: Final analysis of the IFM 2005-02
    • [abstract]. Abstract 310
    • Attal M, Lauwers VC, Marit G, et al. Maintenance treatment with lenalidomide after transplantation for MYELOMA: final analysis of the IFM 2005-02 [abstract]. Blood 2010;116:Abstract 310.
    • (2010) Blood , vol.116
    • Attal, M.1    Lauwers, V.C.2    Marit, G.3
  • 37
    • 77954612946 scopus 로고    scopus 로고
    • Reiterative survival analyses of total therapy 2 for multiple myeloma elucidate follow- Up time dependency of prognostic variables and treatment arms
    • Barlogie B, Anaissie E, van Rhee F, et al. Reiterative survival analyses of total therapy 2 for multiple myeloma elucidate follow- up time dependency of prognostic variables and treatment arms. J Clin Oncol 2010;28:3023-3027.
    • (2010) J Clin Oncol , vol.28 , pp. 3023-3027
    • Barlogie, B.1    Anaissie, E.2    Van Rhee, F.3
  • 40
    • 33644824325 scopus 로고    scopus 로고
    • High-dose therapy and autologous blood stem-cell transplantation compared with conventional treatment in myeloma patients aged 55 to 65 years: Long-term results of a randomized control trial from the Group Myelome-Autogreffe
    • Fermand JP, Katsahian S, Divine M, et al. High-dose therapy and autologous blood stem-cell transplantation compared with conventional treatment in myeloma patients aged 55 to 65 years: long-term results of a randomized control trial from the Group Myelome-Autogreffe. J Clin Oncol 2005;23:9227-9233.
    • (2005) J Clin Oncol , vol.23 , pp. 9227-9233
    • Fermand, J.P.1    Katsahian, S.2    Divine, M.3
  • 41
    • 80052272968 scopus 로고    scopus 로고
    • A phase III study to compare melphalan, prednisone, lenalidomide (MPR) versus melphalan 200 mg/m2 and autologous transplantation (MEL200) in newly diagnosed multiple myeloma patients
    • [abstract]. Abstract 3573
    • Palumbo A, Cavallo F, Hardan I, et al. A phase III study to compare melphalan, prednisone, lenalidomide (MPR) versus melphalan 200 mg/m2 and autologous transplantation (MEL200) in newly diagnosed multiple myeloma patients [abstract]. Blood 2010;116:Abstract 3573.
    • (2010) Blood , vol.116
    • Palumbo, A.1    Cavallo, F.2    Hardan, I.3
  • 42
    • 77952300504 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation for multiple myeloma beyond 2010
    • Bladé J, Rosiñol L, Cibeira MT, et al. Hematopoietic stem cell transplantation for multiple myeloma beyond 2010. Blood 2010;115:3655-3663.
    • (2010) Blood , vol.115 , pp. 3655-3663
    • Bladé, J.1    Rosiñol, L.2    Cibeira, M.T.3
  • 43
    • 0344076348 scopus 로고    scopus 로고
    • Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: An overview of 6,633 patients from 27 randomized trials
    • Myeloma trialists' Collaborative Group
    • Myeloma trialists' Collaborative Group. Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: an overview of 6,633 patients from 27 randomized trials. J Clin Oncol 1998;16:3832-3842.
    • (1998) J Clin Oncol , vol.16 , pp. 3832-3842
  • 44
    • 65349142006 scopus 로고    scopus 로고
    • Thalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma
    • Ludwig H, Hajek R, Tóthová E, et al. Thalidomide- dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma. Blood 2009;113:3435-3442.
    • (2009) Blood , vol.113 , pp. 3435-3442
    • Ludwig, H.1    Hajek, R.2    Tóthová, E.3
  • 46
    • 68949137225 scopus 로고    scopus 로고
    • Efficacy of melphalan and prednisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma: IFM 01/01 trial
    • Hulin C, Facon T, Rodon P, et al. Efficacy of melphalan and prednisone plus thalidomide in patients older than 75 years with newly diagnosed multiple myeloma: IFM 01/01 trial. J Clin Oncol 2009;27:3664-3670.
    • (2009) J Clin Oncol , vol.27 , pp. 3664-3670
    • Hulin, C.1    Facon, T.2    Rodon, P.3
  • 47
    • 78650159700 scopus 로고    scopus 로고
    • Addition of thalidomide to oral melphalan/prednisone in patients with multiple myeloma not eligible for transplantation: Results of a randomized trial from the Turkish Myeloma Study Group
    • Beksac M, Haznedar R, Firatli-Tuglular T, et al. Addition of thalidomide to oral melphalan/prednisone in patients with multiple myeloma not eligible for transplantation: results of a randomized trial from the Turkish Myeloma Study Group. Eur J Haematol 2011;86:16-22.
    • (2011) Eur J Haematol , vol.86 , pp. 16-22
    • Beksac, M.1    Haznedar, R.2    Firatli-Tuglular, T.3
  • 48
    • 77956599686 scopus 로고    scopus 로고
    • Melphalan and prednisone plus thalidomide or placebo in elderly patients with multiple myeloma
    • Waage A, Gimsing P, Fayers P, et al. Melphalan and prednisone plus thalidomide or placebo in elderly patients with multiple myeloma. Blood 2010;116:1405-1412.
    • (2010) Blood , vol.116 , pp. 1405-1412
    • Waage, A.1    Gimsing, P.2    Fayers, P.3
  • 49
    • 77955495783 scopus 로고    scopus 로고
    • Phase III study of the value of thalidomide added to melphalan plus prednisone in elderly patients with newly diagnosed multiple myeloma: The HOVON 49 Study
    • Wijermans P, Schaafsma M, Termorshuizen F, et al. Phase III study of the value of thalidomide added to melphalan plus prednisone in elderly patients with newly diagnosed multiple myeloma: the HOVON 49 Study. J Clin Oncol 2010;28:3160-3166.
    • (2010) J Clin Oncol , vol.28 , pp. 3160-3166
    • Wijermans, P.1    Schaafsma, M.2    Termorshuizen, F.3
  • 50
    • 54049135250 scopus 로고    scopus 로고
    • Oral melphalan, prednisone, and thalidomide in elderly patients with multiple myeloma: Updated results of a randomized controlled trial
    • Palumbo A, Bringhen S, Liberati AM, et al. Oral melphalan, prednisone, and thalidomide in elderly patients with multiple myeloma: updated results of a randomized controlled trial. Blood 2008;112:3107-3114.
    • (2008) Blood , vol.112 , pp. 3107-3114
    • Palumbo, A.1    Bringhen, S.2    Liberati, A.M.3
  • 51
    • 79951894041 scopus 로고    scopus 로고
    • MP versus MPT for previously untreated elderly patients with multiple myeloma: A meta-analysis of 1,682 individual patient data from six randomized clinical trials
    • [abstract]. Abstract 8130
    • Waage A, Palumbo A, Fayers P, et al. MP versus MPT for previously untreated elderly patients with multiple myeloma: a meta-analysis of 1,682 individual patient data from six randomized clinical trials [abstract]. J Clin Oncol 2010;28:Abstract 8130.
    • (2010) J Clin Oncol , vol.28
    • Waage, A.1    Palumbo, A.2    Fayers, P.3
  • 52
    • 50449086728 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
    • San Miguel JF, Schlag R, Khuageva NK, et al. Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. N Engl J Med 2008;359:906-917.
    • (2008) N Engl J Med , vol.359 , pp. 906-917
    • San Miguel, J.F.1    Schlag, R.2    Khuageva, N.K.3
  • 53
    • 77952310929 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisone compared with melphalan and prednisone in previously untreated multiple myeloma: Updated follow-up and impact of subsequent therapy in the phase III VISTA trial
    • Mateos MV, Richardson PG, Schlag R, et al. Bortezomib plus melphalan and prednisone compared with melphalan and prednisone in previously untreated multiple myeloma: updated follow-up and impact of subsequent therapy in the phase III VISTA trial. J Clin Oncol 2010;28:2259-2266.
    • (2010) J Clin Oncol , vol.28 , pp. 2259-2266
    • Mateos, M.V.1    Richardson, P.G.2    Schlag, R.3
  • 54
    • 77957344540 scopus 로고    scopus 로고
    • Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma: A randomised trial
    • Mateos MV, Oriol A, Martínez-López J, et al. Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma: a randomised trial. Lancet Oncol 2010;11:934-941.
    • (2010) Lancet Oncol , vol.11 , pp. 934-941
    • Mateos, M.V.1    Oriol, A.2    Martínez-López, J.3
  • 56
    • 79957447588 scopus 로고    scopus 로고
    • A phase 3 study evaluating the efficacy and safety of lenalidomide combined with melphalan and prednisone in patients ≥ 65 years with newly diagnosed multiple myeloma (NDMM): Continuous use of lenalidomide vs fixed-duration regimens
    • [abstract]. Abstract 622
    • Palumbo A, Delforge M, Catalano J, et al. A phase 3 study evaluating the efficacy and safety of lenalidomide combined with melphalan and prednisone in patients ≥ 65 years with newly diagnosed multiple myeloma (NDMM): continuous use of lenalidomide vs fixed-duration regimens [abstract]. Blood 2010;116:Abstract 622.
    • (2010) Blood , vol.116
    • Palumbo, A.1    Delforge, M.2    Catalano, J.3
  • 57
    • 78650993336 scopus 로고    scopus 로고
    • Bortezomib-melphalan-prednisone-thalidomide followed by maintenance with bortezomib-thalidomide compared with bortezomib-melphalan-prednisone for initial treatment of multiple myeloma: A randomized controlled trial
    • Palumbo A, Bringhen S, Rossi D, et al. Bortezomib-melphalan-prednisone- thalidomide followed by maintenance with bortezomib-thalidomide compared with bortezomib-melphalan-prednisone for initial treatment of multiple myeloma: a randomized controlled trial. J Clin Oncol 2010;28:5101-5109.
    • (2010) J Clin Oncol , vol.28 , pp. 5101-5109
    • Palumbo, A.1    Bringhen, S.2    Rossi, D.3
  • 59
    • 77649215631 scopus 로고    scopus 로고
    • Bortezomib as induction before autologous transplantation, followed by lenalidomide as consolidation-maintenance in untreated multiple myeloma patients
    • Palumbo A, Gay F, Falco P, et al. Bortezomib as induction before autologous transplantation, followed by lenalidomide as consolidation- maintenance in untreated multiple myeloma patients. J Clin Oncol 2010;28:800-807.
    • (2010) J Clin Oncol , vol.28 , pp. 800-807
    • Palumbo, A.1    Gay, F.2    Falco, P.3
  • 60
    • 78649681350 scopus 로고    scopus 로고
    • Efficacy and safety of once-weekly bortezomib in multiple myeloma patients
    • Bringhen S, Larocca A, Rossi D, et al. Efficacy and safety of once-weekly bortezomib in multiple myeloma patients. Blood 2010;116:4745-4753.
    • (2010) Blood , vol.116 , pp. 4745-4753
    • Bringhen, S.1    Larocca, A.2    Rossi, D.3


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