Understanding frailty in the geriatric population

Consultant Pharmacist

Volumn 26, Issue 9, 2011, Pages 634-645

  Wick, Jeannette Y ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Frail elderly; Frailty; Grip strength; Unintentional weight loss; Weakness

Indexed keywords

ARTICLE; COGNITION; ENERGY; ENERGY BALANCE; FRAIL ELDERLY; GRIP STRENGTH; LIFESTYLE; MEMORY; MUSCLE ATROPHY; RESISTANCE TRAINING; WEIGHT REDUCTION;

AGED; AGED, 80 AND OVER; FRAIL ELDERLY; GERIATRIC ASSESSMENT; HUMANS; LIFE STYLE; PHARMACISTS;

EID: 80053975493     PISSN: 08885109     EISSN: None     Source Type: Journal    
DOI: 10.4140/TCP.n.2011.634     Document Type: Article

References (29)

1. Geloo ZS, Ershler WB. Treatment and management of cancer in the frail elderly. CMEondemand. Available at CMEondemand.net/OncSpec/insights-tools/OS701- Geloo.html. Accessed March 2004.
2. Fried LP, Tangen CM, Walston J et al . Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001;56:146-56.
3. Mitnitski AB, Mogilner AJ, Rockwood K. Accumulation of deficits as a proxy measure of aging. Scientific World Journal 2001;1:323-36.
4. Rockwood K, Andrew M, Mitnitski A. A comparison of two approaches to measuring frailty in elderly people. J Gerontol A Biol Sci Med Sci 2007;62:738-43. (Pubitemid 350143605)
5. Robinson TN, Wallace JI, Wu DS et al. Accumulated frailty characteristics predict postoperative discharge institutionalization in the geriatric patient. J Am Coll Surg 2011 Mar 22 [Epub ahead of print].
6. Rockwood K, Song X, Mitnitski A. Changes in relative fitness and frailty across the adult lifespan: evidence from the Canadian National Population Health Survey. CMAJ 2011 Apr 26 [Epub ahead of print].
7. Bandeen-Roche K, Xue QL, Ferrucci L et al. Phenotype of frailty: characterization in the Women's Health and Aging Studies. J Gerontol A Biol Sci Med Sci 2006;61:262-6.
8. Marcell TJ. Sarcopenia: causes, consequences, and preventions. J Gerontol A Biol Sci Med Sci 2003;58:911-6. (Pubitemid 37296685)
9. Roubenoff R. Sarcopenia: a major modifiable cause of frailty in the elderly. J Nutr Health Aging 2000;4:140-2.
10. Guralnik JM, Ferrucci L, Balfour JL et al. Progressive versus catastrophic loss of the ability to walk: implications for the prevention of mobility loss. J Am Geriatr Soc 2001;49:1463-70. (Pubitemid 33051396)
11. Xue QL. The frailty syndrome: definition and natural history. Clin Geriatr Med 2011;27:1-15.
12. Baker PS, Bodner EV, Allman RM. Measuring life-space mobility in community-dwelling older adults. J Am Geriatr Soc 2003;51:1610-4. (Pubitemid 37409596)
13. Peel C, Sawyer Baker P, Roth DL et al. Assessing mobility in older adults: the UAB Study of Aging Life-Space Assessment. Phys Ther 2005;85:1008-119.
14. Xue QL, Fried LP, Glass TA et al. Life-space constriction, development of frailty, and the competing risk of mortality: the Women's Health And Aging Study I. Am J Epidemiol 2008;167:240-8.
15. Gill TM, Gahbauer EA, Allore HG et al. Transitions between frailty states among community-living older persons. Arch Intern Med 2006;166:418-23.
16. Wallace JI, Schwartz RS, LaCroix AZ et al. Involuntary weight loss in older outpatients: incidence and clinical significance. J Am Geriatr Soc 1995;43:329-37.
17. Drey M, Wehr H, Wehr G et al. The frailty syndrome in general practitioner care: a pilot study. Z Gerontol Geriatr 2011;44:48-54.
18. Blyth FM, Rochat S, Cumming RG et al. Pain, frailty and comorbidity on older men: the CHAMP study. Pain 2008;140: 224-30.
19. Buchman AS, Boyle PA, Wilson RS et al. Frailty is associated with incident Alzheimer's disease and cognitive decline in the elderly. Psychosom Med 2007;69:483-9. (Pubitemid 46987892)
20. Markle-Reid M, Browne G. Conceptualizations of frailty in relation to older adults. J Adv Nurs 2003;44:58-68. (Pubitemid 37352310)
21. Timonen L, Rantanen T, Mäkinen E et al. Effects of a group-based exercise program on functional abilities in frail older women after hospital discharge. Aging Clin Exp Res 2006;18:50-6.
22. Sullivan DH, Roberson PK, Smith ES et al. Effects of muscle strength training and megestrol acetate on strength, muscle mass, and function in frail older people. J Am Geriatr Soc 2007;55:20-8. (Pubitemid 46046224)
23. Chin A Paw MJ, van Uffelen JG, Riphagen I et al. The functional effects of physical exercise training in frail older people: a systematic review. Sports Med 2008;38:781-93.
24. Steib S, Schoene D, Pfeifer K. Dose-response relationship of resistance training in older adults: a meta-analysis. Med Sci Sports Exerc 2010;42:902-14.
25. Mallery LH, Moorhouse P. Respecting frailty. J Med Ethics 2011;37:126-8.
26. Frailty not a factor in adverse drug reactions among seniors, study finds. States News Service 2011 April 6.
27. Fick DM, Mion LC, Beers MH et al. Health outcomes associated with potentially inappropriate medication use in older adults. Res Nurs Health 2008;31:42-51.
28. Fick DM, Cooper JW, Wade WE et al. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med 2003;163:2716-24. (Pubitemid 37517412)
29. Chaves PH, Semba RD, Leng SX et al. Impact of anemia and cardiovascular disease on frailty status of community-dwelling older women: the Women's Health and Aging Studies I and II. J Gerontol A Biol Sci Med Sci 2005;60:729-35. (Pubitemid 40881179)