Three copies of isochromosome 8q in Ph+ B-cell acute lymphoblastic leukemia

Leukemia Research

Volumn 35, Issue 11, 2011, Pages

  Soriani, Silvia ^a   Fedeli, Fausto ^b   Molteni, Alfredo ^b   Grillo, Giovanni ^b   Tedeschi, Alessandra ^b   Scarpati, Barbara ^b   Campidelli, Cristina ^b   Leszl, Anna ^c   Farioli, Renata ^b   De Canal, Gabriella ^b   Mura, Maria Angela ^b   Cesana, Clara ^b  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b OSPEDALE NIGUARDA CA GRANDA   (Italy)

^c UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BCR ABL PROTEIN; BILIRUBIN; CD19 ANTIGEN; CD20 ANTIGEN; CD22 ANTIGEN; CD3 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; CD79A ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; CYTARABINE; HEMOGLOBIN; HLA DR ANTIGEN; IMATINIB; LACTATE DEHYDROGENASE; MITOXANTRONE; PROTEIN P190; URIC ACID;

ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; AVIAN MYELOBLASTOSIS VIRUS; BLAST CELL CRISIS; BLOOD SMEAR; BONE MARROW BIOPSY; CASE REPORT; CHROMOSOME 11Q; CHROMOSOME 8; CHROMOSOME 8Q; CHROMOSOME BANDING PATTERN; CHROMOSOME TRANSLOCATION; CYTOGENETICS; DRUG MEGADOSE; FATIGUE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DOSAGE; GENE LOCUS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPHENOTYPING; INTERPHASE; ISOCHROMOSOME; JAUNDICE; KARYOTYPE; KARYOTYPE 48,XY; LETTER; LEUKEMIA REMISSION; LEUKOCYTE COUNT; LEUKOCYTOSIS; LYMPHOCYTE COUNT; MALE; METAPHASE; MONOCYTE; NEUTROPHIL COUNT; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLENOMEGALY; SUPERNUMERARY CHROMOSOME; THROMBOCYTE COUNT; THROMBOCYTOPENIA;

ACUTE DISEASE; ADOLESCENT; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 8; GENE DOSAGE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; ISOCHROMOSOMES; KARYOTYPING; MALE; PHILADELPHIA CHROMOSOME; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA;

EID: 80053969558     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2011.06.033     Document Type: Letter

References (19)

1. Borowitz M.J., Béné M.C., Harris N.L., Porwit A., Matutes E. Acute leukemia of ambiguous lineage. WHO classification of tumours of haematopoietic and lymphoid tissues 2008, 149-152. International Agency for Research on Cancer (IARC), Lyon, France. 4th ed. S.H. Swerdlow, E. Campo, N.L. Harris, E.S. Jaffe, S.A. Pileri, H. Stein, J. Thiele, J.W. Vardiman (Eds.).
2. Pieters R., Carroll W.L. Biology and treatment of acute lymphoblastic leukemia. Hematol Oncol Clin North Am 2010, 24:1-18.
3. Li Y., Qiu L., Zou D., Zhao Y., Mi Y., Wang J. Additional chromosomal abnormalities and their prognostic significance in adult Philadelphia-positive acute lymphoblastic leukemia: with or without imatinib in chemotherapy. Ann Hematol 2009, 88:1069-1077.
4. Mertens F., Johansson B., Mitelman F. Isochromosomes in neoplasia. Genes Chromosomes Cancer 1994, 10:221-230.
5. Mossafa H., Huret J.L., Brizard A., Guilhot F., Lessard M., Tanzer J. Isochromosome 8q: a new recurring secondary anomaly in adults with B-lineage acute lymphoid leukemia. Cancer Genet Cytogenet 1994, 73:84-85.
6. Au W.Y., Ma S.K., Wan T.S., Man C., Kwong Y.L. Pentasomy 8q in therapy-related myelodysplastic syndrome due to cyclophosphamide therapy for fibrosing alveolitis. Cancer Genet Cytogenet 2003, 141:79-82.
7. Vicari L., Sebastio L., Cirigliano V., Pugliese M.T., Ferrara F. Double isochromosome 8q as single cytogenetic aberration in acute myelo-monocytic leukemia. Leuk Lymphoma 1995, 19:351-353.
8. Flohr T., Schrauder A., Cazzaniga G., Panzer-Grümayer R., van der Velden V., Fischer S., et al. Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia. Leukemia 2008, 22:771-782.
9. De Braekeleer E., Basinko A., Douet-Guilbert N., Morel F., Le Bris M.J., Berthou C. Cytogenetics in pre-B and B-cell acute lymphoblastic leukemia: a study of 208 patients diagnosed between 1981 and 2008. Cancer Genet Cytogenet 2010, 200:8-15.
10. Mrozek K., Harper D.P. Cytogenetics and molecular genetics of acute lymphoblastic leukemia. Hematol Oncol Clin N Am 2009, 23:991-1010.
11. Pui C.H., Carroll A.J., Raimondi S.C., Schell M.J., Head D.R., Shuster J.J., et al. Isochromosomes in childhood acute lymphoblastic leukemia: a collaborative study of 83 cases. Blood 1992, 79:2384-2391.
12. Magrini E., Pragliola A., Fantasia D., Calabrese G., Gaiba A., Farnedi A., et al. Acquisition of i(8q) as an early event in malignant triton tumors. Cancer Genet Cytogenet 2004, 154:150-155.
13. Beverstock G.C., Wessels H.W., Mollevanger P., den Ottolander G.J., Gottlieb D.J. A second case of hexasomy 8 in myelodysplastic syndrome. Cancer Genet Cytogenet 1997, 99:68-72.
14. Beyera V., Mühlemattera D., Parliera V., Cabrolb C., Bougeon-Mamina S., Solenthalerc M., et al. Polysomy 8 defines a clinico-cytogenetic entity representing a subset of myeloid hematologic malignancies associated with a poor prognosis: report on a cohort of 12 patients and review of 105 published cases. Cancer Genet Cytogenet 2005, 160:97-119.
15. Kwong Y.L., Chan T.K. Pentasomy 8q in myelodysplasia. Cancer Genet Cytogenet 1998, 100:179-181.
16. Ferro M.T., Vázquez-Mazariego Y., Ramiro S., Santiago M.F., García-Sagredo J.M., Nuñez R., et al. Trisomy/tetrasomy of chromosome 8 and +i(8q) as the sole chromosome abnormality in three adult patients with myelomonocytic leukemia. Cancer Genet Cytogenet 2000, 120:163-165.
17. OMIM: Online Mendelian Inheritance in Man. http://www.ncbi.nlm.nih.gov/omim.
18. Dominguez-Sola D., Ying C.Y., Grandori C., Ruggiero L., Chen B., Li M., et al. Non-transcriptional control of DNA replication by c-Myc. Nature 2007, 448:445-451.
19. Faderl S., O'Brien S., Pui C.H., Stock W., Wetzler M., Hoelzer D., et al. Adult acute lymphoblastic leukemia: concepts and strategies. Cancer 2010, 116:1165-1176.