Reply to: Fractional synthesis and clearance rates for amyloid β

Nature Medicine

Volumn 17, Issue 10, 2011, Pages 1179-1180

  Elbert, Donald L ^a   Patterson, Bruce W ^b   Ercole, Lindsay ^b   Ovod, Vitaliy ^b   Kasten, Tom ^b   Mawuenyega, Kwasi ^b   Yarasheski, Kevin ^b   Morris, John C ^b   Benzinger, Tammie ^b   Holtzman, David M ^b   Bateman, Randall J ^b  

^a WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN;

ALZHEIMER DISEASE; BRAIN; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; COMPARTMENT MODEL; CONTROLLED STUDY; HUMAN; ISOTOPE LABELING; KINETICS; LETTER; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

EID: 80053962797     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2496     Document Type: Letter

References (8)

1. Edland, S.D. & Galasko, D.R. et al. Nat. Med. 17, 1178-1179 (2011).
2. Bateman, R.J. et al. Nat. Med. 12, 856-861 (2006).
3. Bateman, R.J. et al. Ann. Neurol. 66, 48-54 (2009).
4. Mawuenyega, K.G. et al. Science 330, 1774 (2010).
5. Wolfe, R.R. & Chinkes, D.L. Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis 2nd edn., Chapter 13 (Wiley-Liss, Hoboken, New Jersey, 2005).
6. Zilversmit, D.B. Am. J. Med. 29, 832-848 (1960).
7. Holtzman, D., Bateman, R. & Kim, J. Methods for measuring the metabolism of CNS derived biomolecules in vivo. US patent application 2009/0142766 A1.
8. Wildsmith, K.R., Han, B. & Bateman, R.J. Anal. Biochem. 395, 116-118 (2009).