Role of 657del5 NBN mutation and 7p12.2 (IKZF1), 9p21 (CDKN2A), 10q21.2 (ARID5B) and 14q11.2 (CEBPE) variation and risk of childhood ALL in the Polish population

Leukemia Research

Volumn 35, Issue 11, 2011, Pages 1534-1536

  Pastorczak, Agata ^a   Górniak, Patryk ^a   Sherborne, Amy ^b   Hosking, Fay ^b   Trelińska, Joanna ^a   Lejman, Monika ^c   Szczepański, Tomasz ^d   Borowiec, Maciej ^a   Fendler, Wojciech ^a   Kowalczyk, Jerzy ^c   Houlston, Richard S ^b   Młynarski, Wojciech ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^d MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Acute lymphoblastic leukemia; Genetics; Risk

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARID5B GENE; ARTICLE; CANCER RISK; CASE CONTROL STUDY; CDKN2A GENE; CEBPE GENE; CHILD; CHILDHOOD LEUKEMIA; CHROMOSOME 10Q; CHROMOSOME 14Q; CHROMOSOME 7P; CHROMOSOME 8Q; CHROMOSOME 9P; CONTROLLED STUDY; FEMALE; GENE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; IKZF1 GENE; INFANT; LEUKEMOGENESIS; MAJOR CLINICAL STUDY; MALE; NBN GENE; POLAND; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD;

ADOLESCENT; ANTIGENS, NEOPLASM; CASE-CONTROL STUDIES; CCAAT-ENHANCER-BINDING PROTEINS; CELL CYCLE PROTEINS; CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 10; CHROMOSOMES, HUMAN, PAIR 14; CHROMOSOMES, HUMAN, PAIR 7; CHROMOSOMES, HUMAN, PAIR 9; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA; DNA MUTATIONAL ANALYSIS; FEMALE; GENOTYPE; HUMANS; IKAROS TRANSCRIPTION FACTOR; INFANT; MALE; MUTATION; NEOPLASM PROTEINS; NUCLEAR PROTEINS; POLAND; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROGNOSIS;

EID: 80053953634     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2011.07.034     Document Type: Article

References (13)

1. Stiller C.A., Parkin D.M. Geographic and ethnic variations in the incidence of childhood cancer. British Medical Bulletin 1996, 52:682-703.
2. Pui C., Childhood Leukemias 2007, Cambridge Press, New York. 2nd ed.
3. Papaemmanuil E., Hosking F.J., Vijayakrishnan J., Price A., Olver B., Sheridan E., et al. Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. Nature Genetics 2009, 41:1006-1010.
4. Trevino L.R., Yang W., French D., Hunger S.P., Carroll W.L., Devidas M., et al. Germline genomic variants associated with childhood acute lymphoblastic leukemia. Nature Genetics 2009, 41:1001-1005.
5. Sherborne A.L., Hosking F.J., Prasad R.B., Kumar R., Koehler R., Vijayakrishnan J., et al. Variation in CDKN2A at 9p21.3 influences childhood acute lymphoblastic leukemia risk. Nature Genetics 2010, 42:492-494.
6. Chrzanowska K.H., Piekutowska-Abramczuk D., Popowska E., Gładkowska-Dura M., Małdyk J., Syczewska M., et al. Carrier frequency of mutation 657del5 in the NBS1 gene in a population of polish pediatric patients with sporadic lymphoid malignancies. International Journal of Cancer 2006, 118:1269-1274.
7. Cerosaletti K.M., Lange E., Stringham H.M., Weemaes C.M.R., Smeets D., Sölder B., et al. Fine localization of the Nijmegen breakage syndrome gene to 8q21: evidence for a common founder haplotype. American Journal of Human Genetics 1998, 63:125-134.
8. Borowiec M., Fendler W., Antosik K. Optimization of monogenic diabetes screening programme - initial report on recruitment efficacy of the TEAM project. Pediatric Endocrinology, Diabetes and Metabolism 2010, 16:73-76.
9. Georgopoulos K., Bigby M., Wang J-H., Molnar A., Wu P., Winandy S., et al. The ikaros gene is required for the development of all lymphoid lineages. Cell 1994, 79:143-156.
10. Wilsker D., Patsialou A., Dallas P.B., Moran E. ARID Proteins: a diverse family of DNA binding proteins implicated in the control of cell growth, differentiation, and development. Cell Growth & Differentiation 2002, 13:95-106.
11. Akasaka T., Balasas T., Russell L.J., Sugimoto K-j, Majid A., Walewska R., et al. Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Blood 2007, 109:3451-3461.
12. Weemaes C.M.R., Hustinx T.W.J., Scheres J.M.J.C., Munster P.J.J.V., Bakkeren J.A.J.M., Taalman R.D.F.M. A new chromosomal instability disorder: the Nijmegen breakage syndrome. Acta Paediatrica 1981, 70:557-564.
13. Resnick I.B., Kondratenko I., Pashanov E., Maschan A.A., Karachunsky A., Togoev O., et al. 657del5 mutation in the gene for Nijmegen breakage syndrome (NBS1) in a cohort of Russian children with lymphoid tissue malignancies and controls. American Journal of Medical Genetics Part A 2003, 120A:174-179.