Acquired alpha thalassemia myelodyslastic/myeloproliferative syndrome (ATMDS): Evolution on hypomethylating agent therapy

Leukemia Research

Volumn 35, Issue 11, 2011, Pages

  Rose, Christian ^a   Fournier, Martine ^a   Nibourel, Olivier ^a   Herbaux, Charles ^a   Charpentier, Agnes ^a   Renneville, Aline ^a   Pissard, Serge ^b   Badens, Catherine ^c   Preudhomme, Claude ^a  

^a UNIV LILLE   (France)

^b HENRI MONDOR HOSPITAL   (France)

^c TIMONE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLOBIN; AZACITIDINE; HEMOGLOBIN; HEMOGLOBIN H;

ACQUIRED ALPHA THALASSEMIA MYELODYSPLASTIC SYNDROME; ACQUIRED ALPHA THALASSEMIA MYELOPROLIFERATIVE SYNDROME; AGED; ANEMIA; ASLX GENE; ATRX GENE; BLOOD ANALYSIS; BLOOD CELL COUNT; BONE MARROW BIOPSY; CASE REPORT; CHRONIC MYELOMONOCYTIC LEUKEMIA; DEATH; ERYTHROCYTE TRANSFUSION; EXON; FOLLOW UP; GENE; GENE DELETION; GENE LOCUS; GENETIC ANALYSIS; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN TISSUE; HYPERLEUKOCYTOSIS; LETTER; LEUKOCYTOSIS; MALE; MULTIPLE CYCLE TREATMENT; MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; MYELODYSPLASTIC SYNDROME; MYELOPROLIFERATIVE DISORDER; NONSENSE MUTATION; PALLOR; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TET2 GENE;

AGED; ALPHA-THALASSEMIA; ANTIMETABOLITES, ANTINEOPLASTIC; AZACITIDINE; DNA METHYLATION; EVOLUTION, MOLECULAR; FATAL OUTCOME; HUMANS; LEUKEMIA, MYELOMONOCYTIC, CHRONIC; MALE; SYNDROME;

EID: 80053953436     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2011.07.010     Document Type: Letter

References (5)

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2. Serrano E., Lasa A., Perea G., Carnicer M.J., Brunet S., Aventin A., et al. Acute myeloid leukemia subgroups identified by pathway-restricted gene expression signatures. Acta Haematol 2006, 116(2):77-89.
3. Costa D.B., Fisher C.A., Miller K.B., Pihan G.A., Steensma D.P., Gibbons R.J., et al. A novel mutation in the last exon of ATRX in a patient with alpha-thalassemia myelodysplastic syndrome. Eur J Haematol 2006, 76(5):432-435.
4. Gibbons R.J., Pellagatti A., Garrick D., Wood W.G., Malik N., Ayyub H., et al. Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the alpha-thalassemia myelodysplasia syndrome (ATMDS). Nat Genet 2003, 34(4):446-449.
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