Amiloride is a competitive inhibitor of coxsackievirus B3 RNA polymerase

Journal of Virology

Volumn 85, Issue 19, 2011, Pages 10364-10374

  Gazina, Elena V ^a   Smidansky, Eric D ^b   Holien, Jessica K ^c   Harrison, David N ^a,f   Cromer, Brett A ^d   Arnold, Jamie J ^b   Parker, Michael W ^c,e   Cameron, Craig E ^b   Petrou, Steven ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d RMIT UNIVERSITY   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

^f BURNET INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

5 (N ETHYL N ISOPROPYL)AMILORIDE; AMILORIDE; MAGNESIUM ION; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; NUCLEOSIDE TRIPHOSPHATE; RNA DEPENDENT RNA POLYMERASE 3D; RNA DIRECTED RNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

ANTIVIRAL ACTIVITY; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; COXSACKIE VIRUS B3; DRUG BINDING SITE; IN VITRO STUDY; MOLECULAR DOCKING; MOLECULAR MECHANICS; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; RNA TRANSLATION;

AMILORIDE; ANTIVIRAL AGENTS; BINDING SITES; DNA-DIRECTED RNA POLYMERASES; ENTEROVIRUS B, HUMAN; ENZYME INHIBITORS; MAGNESIUM; MODELS, MOLECULAR; NUCLEOTIDES; PROTEIN BINDING;

COXSACKIEVIRUS;

EID: 80053942786     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05022-11     Document Type: Article

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