Adult women with acne have a higher risk of elevated triglyceride levels with the use of oral isotretinoin;Mulheres adultas com acne apresentam maior risco de elevação de triglicerídeos ao uso de isotretinoína oral

Anais Brasileiros de Dermatologia

Volumn 86, Issue 4, 2011, Pages 807-810

  Schmitt, Juliano Vilaverde ^a   Tavares, Mariana ^b   Cerci, Felipe Bochnia ^b  

^a Curitiba Evangelical Teaching Hospital   (Brazil)

^b Dermatology Outpatient Clinic   (Brazil)

Author keywords

Acne vulgaris; Hyperlipidemias; Isotretinoin; Retinoids; Women

Indexed keywords

CHOLESTEROL; ISOTRETINOIN; TRIACYLGLYCEROL;

ACNE; ADULT; CHOLESTEROL BLOOD LEVEL; FEMALE; HIGH RISK PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; RETREATMENT; REVIEW; TRIACYLGLYCEROL BLOOD LEVEL;

ACNE VULGARIS; ADMINISTRATION, ORAL; ADOLESCENT; ADULT; FEMALE; HUMANS; ISOTRETINOIN; LIPIDS; MALE; RETROSPECTIVE STUDIES; RISK FACTORS; SEX FACTORS; TRIGLYCERIDES;

EID: 80053941249     PISSN: 03650596     EISSN: 18064841     Source Type: Journal    
DOI: 10.1590/S0365-05962011000400033     Document Type: Review

References (7)

1. Schmitt JV, Masuda PY, Miot HA. Padrões clínicos de acne em mulheres de diferentes faixas etárias. An Bras Dermatol. 2009;84:349-54.
2. Zane LT, Leyden WA, Marqueling AL, Manos MM. A population-based analysis of laboratory abnormalities during isotretinoin therapy for acne vulgaris. Arch Dermatol. 2006;142:1016-22.
3. De Marchi MA, Maranhão RC, Brandizzi LI, Souza DR. Effects of isotretinoin on the metabolism of triglyceride-rich lipoproteins and on the lipid profile in patients with acne. Arch Dermatol Res. 2006;297:403-8.
4. Tallab T, Joharji H, Jazei M, Bahamdan K, Ibrahim K, Karkashan E. Isotretinoin therapy: any need for laboratory assessment? West Afr J Med. 2004;23:273-5.
5. Vu-Dac N, Gervois P, Torra IP, Fruchart JC, Kosykh V, Kooistra T, et al. Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor. Contribution to the hypertriglyceridemic action of retinoids. J Clin Invest. 1998;102:625-32.
6. Pham T, Scofield RH. 13-cis-Retinoic acid (isotretinoin) unmasking of clinical polycystic ovary syndrome. Endocr Pract. 2007;13:776-9.
7. Rodondi N, Darioli R, Ramelet AA, Hohl D, Lenain V, Perdrix J, et al. High risk for hyperlipidemia and the metabolic syndrome after an episode of hypertriglyceridemia during 13-cis retinoic acid therapy for acne: a pharmacogenetic study. Ann Intern Med. 2002;136:582-9.