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Volumn 6, Issue 10, 2011, Pages

Magnetic resonance spectroscopy detectable metabolomic fingerprint of response to antineoplastic treatment

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALANINE; BETA ACTIN; CITRIC ACID; FUMARIC ACID; GLUTAMINE; GLUTATHIONE; INITIATION FACTOR 4E BINDING PROTEIN 1; LACTIC ACID; PHOSPHORYLCHOLINE; RAF PROTEIN; TANESPIMYCIN; 17-(ALLYLAMINO)-17-DEMETHOXYGELDANAMYCIN; ANTINEOPLASTIC AGENT; BENZOQUINONE DERIVATIVE; MACROCYCLIC LACTAM;

EID: 80053934312     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026155     Document Type: Article
Times cited : (38)

References (60)
  • 1
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O, (1956) On the origin of cancer cells. Science 123: 309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 2
    • 52649107626 scopus 로고    scopus 로고
    • Cancer cell metabolism: Warburg and beyond
    • Hsu PP, Sabatini DM, (2008) Cancer cell metabolism: Warburg and beyond. Cell 134: 703-707.
    • (2008) Cell , vol.134 , pp. 703-707
    • Hsu, P.P.1    Sabatini, D.M.2
  • 3
    • 77953209898 scopus 로고    scopus 로고
    • Q&A: Cancer: Clues from cell metabolism
    • Kaelin WG, Thompson CB, (2010) Q&A: Cancer: Clues from cell metabolism. Nature 465: 562-564.
    • (2010) Nature , vol.465 , pp. 562-564
    • Kaelin, W.G.1    Thompson, C.B.2
  • 4
    • 61849135453 scopus 로고    scopus 로고
    • Tumor suppressors and cell metabolism: A recipe for cancer growth
    • Jones RG, Thompson CB, (2009) Tumor suppressors and cell metabolism: A recipe for cancer growth. Genes Dev 23: 537-548.
    • (2009) Genes Dev , vol.23 , pp. 537-548
    • Jones, R.G.1    Thompson, C.B.2
  • 5
    • 54249093810 scopus 로고    scopus 로고
    • Hyperpolarized 13C lactate, pyruvate, and alanine: Noninvasive biomarkers for prostate cancer detection and grading
    • Albers MJ, Bok R, Chen AP, Cunningham CH, Zierhut ML, et al. (2008) Hyperpolarized 13C lactate, pyruvate, and alanine: Noninvasive biomarkers for prostate cancer detection and grading. Cancer Res 68: 8607-8615.
    • (2008) Cancer Res , vol.68 , pp. 8607-8615
    • Albers, M.J.1    Bok, R.2    Chen, A.P.3    Cunningham, C.H.4    Zierhut, M.L.5
  • 6
    • 35948970970 scopus 로고    scopus 로고
    • Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy
    • Day SE, Kettunen MI, Gallagher FA, Hu D-E, Lerche M, et al. (2007) Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy. Nat Med 13: 1382-1387.
    • (2007) Nat Med , vol.13 , pp. 1382-1387
    • Day, S.E.1    Kettunen, M.I.2    Gallagher, F.A.3    Hu, D.-E.4    Lerche, M.5
  • 7
    • 78650968872 scopus 로고    scopus 로고
    • On-target inhibition of tumor fermentative glycolysis as visualized by hyperpolarized pyruvate
    • Seth P, Grant A, Tang J, Vinogradov E, Wang X, et al. (2001) On-target inhibition of tumor fermentative glycolysis as visualized by hyperpolarized pyruvate. Neoplasia 13: 60-71.
    • (2001) Neoplasia , vol.13 , pp. 60-71
    • Seth, P.1    Grant, A.2    Tang, J.3    Vinogradov, E.4    Wang, X.5
  • 8
    • 0041984595 scopus 로고    scopus 로고
    • 18FDG-Positron emission tomography for the early prediction of response in advanced soft tissue sarcoma treated with imatinib mesylate (Glivec)
    • Stroobants S, Goeminne J, Seegers M, Dimitrijevic S, Dupont P, et al. (2003) 18FDG-Positron emission tomography for the early prediction of response in advanced soft tissue sarcoma treated with imatinib mesylate (Glivec). Eur J Cancer 39: 2012-2020.
    • (2003) Eur J Cancer , vol.39 , pp. 2012-2020
    • Stroobants, S.1    Goeminne, J.2    Seegers, M.3    Dimitrijevic, S.4    Dupont, P.5
  • 9
    • 64849106898 scopus 로고    scopus 로고
    • FDG-PET to measure response to targeted therapy: The example of gastrointestinal stromal tumor and imatinib mesylate (Gleevec)
    • Van den Abbeele AD, Ertuk M, (2008) FDG-PET to measure response to targeted therapy: The example of gastrointestinal stromal tumor and imatinib mesylate (Gleevec). PET Clinics 3: 77-87.
    • (2008) PET Clinics , vol.3 , pp. 77-87
    • van den Abbeele, A.D.1    Ertuk, M.2
  • 10
    • 76749161366 scopus 로고    scopus 로고
    • Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy
    • Ward CS, Venkatesh HS, Chaumeil MM, Brandes AH, VanCriekinge M, et al. (2010) Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy. Cancer Res 70: 1296-1305.
    • (2010) Cancer Res , vol.70 , pp. 1296-1305
    • Ward, C.S.1    Venkatesh, H.S.2    Chaumeil, M.M.3    Brandes, A.H.4    VanCriekinge, M.5
  • 11
    • 77957343186 scopus 로고    scopus 로고
    • Hyperpolarized 13C spectroscopic imaging informs on hypoxia-inducible factor-1 and Myc activity downstream of platelet-derived growth factor receptor
    • Dafni H, Larson PEZ, Hu S, Yoshihara HAI, Ward CS, et al. (2010) Hyperpolarized 13C spectroscopic imaging informs on hypoxia-inducible factor-1 and Myc activity downstream of platelet-derived growth factor receptor. Cancer Res 70: 7400-7410.
    • (2010) Cancer Res , vol.70 , pp. 7400-7410
    • Dafni, H.1    Larson, P.E.Z.2    Hu, S.3    Yoshihara, H.A.I.4    Ward, C.S.5
  • 12
    • 33750383279 scopus 로고    scopus 로고
    • Choline phospholipid metabolism in cancer: Consequences for molecular pharmaceutical interventions
    • Glunde K, Ackerstaff E, Mori N, Jacobs MA, Bhujwalla ZM, (2006) Choline phospholipid metabolism in cancer: Consequences for molecular pharmaceutical interventions. Mol Pharm 3: 496-506.
    • (2006) Mol Pharm , vol.3 , pp. 496-506
    • Glunde, K.1    Ackerstaff, E.2    Mori, N.3    Jacobs, M.A.4    Bhujwalla, Z.M.5
  • 14
    • 0032424029 scopus 로고    scopus 로고
    • Volume localized in vivo proton MR spectroscopy of breast carcinoma: Variation of water-fat ratio in patients receiving chemotherapy
    • Jagannathan NR, Singh M, Govindaraju V, Raghunathan P, Coshic O, et al. (1998) Volume localized in vivo proton MR spectroscopy of breast carcinoma: Variation of water-fat ratio in patients receiving chemotherapy. NMR Biomed 11: 414-422.
    • (1998) NMR Biomed , vol.11 , pp. 414-422
    • Jagannathan, N.R.1    Singh, M.2    Govindaraju, V.3    Raghunathan, P.4    Coshic, O.5
  • 15
    • 0030056928 scopus 로고    scopus 로고
    • Three-dimensional H-1 MR spectroscopic imaging of the in situ human prostate with high (0.24-0.1-cm(3)) spatial resolution
    • Kurhanewicz J, Vigneron DB, Hricak H, Narayan P, Carroll P, et al. (1996) Three-dimensional H-1 MR spectroscopic imaging of the in situ human prostate with high (0.24-0.1-cm(3)) spatial resolution. Radiology 198: 795-805.
    • (1996) Radiology , vol.198 , pp. 795-805
    • Kurhanewicz, J.1    Vigneron, D.B.2    Hricak, H.3    Narayan, P.4    Carroll, P.5
  • 16
    • 13844281128 scopus 로고    scopus 로고
    • Loss of p53 function in colon cancer cells results in increased phosphocholine and total choline
    • Mori N, Delsite R, Natarajan K, Kulawiec M, Bhujwalla ZM, et al. (2004) Loss of p53 function in colon cancer cells results in increased phosphocholine and total choline. Mol Imaging 3: 319-323.
    • (2004) Mol Imaging , vol.3 , pp. 319-323
    • Mori, N.1    Delsite, R.2    Natarajan, K.3    Kulawiec, M.4    Bhujwalla, Z.M.5
  • 17
    • 0032951381 scopus 로고    scopus 로고
    • Increased choline kinase activity and elevated phosphocholine levels in human colon cancer
    • Nakagami K, Uchida T, Ohwada S, Koibuchi Y, Suda Y, et al. (1999) Increased choline kinase activity and elevated phosphocholine levels in human colon cancer. Japanese Journal Cancer Research 90: 419-424.
    • (1999) Japanese Journal Cancer Research , vol.90 , pp. 419-424
    • Nakagami, K.1    Uchida, T.2    Ohwada, S.3    Koibuchi, Y.4    Suda, Y.5
  • 18
    • 0031713186 scopus 로고    scopus 로고
    • Human breast lesions: Characterization with proton MR spectroscopy
    • Roebuck JR, Cecil KM, Schnall MD, Lenkinski RE, (1998) Human breast lesions: Characterization with proton MR spectroscopy. Radiology 209: 269-275.
    • (1998) Radiology , vol.209 , pp. 269-275
    • Roebuck, J.R.1    Cecil, K.M.2    Schnall, M.D.3    Lenkinski, R.E.4
  • 19
    • 0028695478 scopus 로고
    • Clinical applications of magnetic resonance spectroscopy
    • Ross B, Michaelis T, (1994) Clinical applications of magnetic resonance spectroscopy. Magn Reson Q 10: 191-247.
    • (1994) Magn Reson Q , vol.10 , pp. 191-247
    • Ross, B.1    Michaelis, T.2
  • 20
    • 0034969284 scopus 로고    scopus 로고
    • Human breast lesions: Characterization with contrast-enhanced in vivo proton MR spectroscopy - Initial results
    • Yeung DKW, Cheung HS, Tse GMK, (2001) Human breast lesions: Characterization with contrast-enhanced in vivo proton MR spectroscopy- Initial results. Radiology 220: 40-46.
    • (2001) Radiology , vol.220 , pp. 40-46
    • Yeung, D.K.W.1    Cheung, H.S.2    Tse, G.M.K.3
  • 21
    • 77954358936 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase inhibitor PI-103 downregulates choline kinase alpha leading to phosphocholine and total choline decrease detected by magnetic resonance spectroscopy
    • Al-Saffar NMS, Jackson LE, Raynaud FI, Clarke PA, de Molina AR, et al. (2010) The phosphoinositide 3-kinase inhibitor PI-103 downregulates choline kinase alpha leading to phosphocholine and total choline decrease detected by magnetic resonance spectroscopy. Cancer Res 70: 5507-5517.
    • (2010) Cancer Res , vol.70 , pp. 5507-5517
    • Al-Saffar, N.M.S.1    Jackson, L.E.2    Raynaud, F.I.3    Clarke, P.A.4    de Molina, A.R.5
  • 22
    • 33644866627 scopus 로고    scopus 로고
    • Identification of magnetic resonance detectable metabolic changes associated with inhibition of phosphoinositide 3-kinase signaling in human breast cancer cells
    • Beloueche-Babari M, Jackson LE, Al-Saffar NMS, Eccles SA, Raynaud FI, et al. (2006) Identification of magnetic resonance detectable metabolic changes associated with inhibition of phosphoinositide 3-kinase signaling in human breast cancer cells. Mol Cancer Ther 5: 187-196.
    • (2006) Mol Cancer Ther , vol.5 , pp. 187-196
    • Beloueche-Babari, M.1    Jackson, L.E.2    Al-Saffar, N.M.S.3    Eccles, S.A.4    Raynaud, F.I.5
  • 23
    • 66849138226 scopus 로고    scopus 로고
    • Changes in choline metabolism as potential biomarkers of phospholipase C gamma 1 inhibition in human prostate cancer cells
    • Beloueche-Babari M, Peak JC, Jackson LE, Tiet MY, Leach MO, et al. (2009) Changes in choline metabolism as potential biomarkers of phospholipase C gamma 1 inhibition in human prostate cancer cells. Mol Cancer Ther 8: 1305-1311.
    • (2009) Mol Cancer Ther , vol.8 , pp. 1305-1311
    • Beloueche-Babari, M.1    Peak, J.C.2    Jackson, L.E.3    Tiet, M.Y.4    Leach, M.O.5
  • 24
    • 77957815253 scopus 로고    scopus 로고
    • 17-allyamino-17-demethoxygeldanamycin treatment results in a magnetic resonance spectroscopy-detectable elevation in choline-containing metabolites associated with increased expression of choline transporter SLC44A1 and phospholipase A2
    • Brandes A, Ward C, Ronen SM, (2010) 17-allyamino-17-demethoxygeldanamycin treatment results in a magnetic resonance spectroscopy-detectable elevation in choline-containing metabolites associated with increased expression of choline transporter SLC44A1 and phospholipase A2. Breast Cancer Res 12: R84.
    • (2010) Breast Cancer Res , vol.12
    • Brandes, A.1    Ward, C.2    Ronen, S.M.3
  • 25
    • 0344393470 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopic pharmacodynamic markers of the heat shock protein 90 inhibitor 17-allylamino,17-demethoxygeldanamycin (17AAG) in human colon cancer models
    • Chung YL, Troy H, Banerji U, Jackson LE, Walton MI, et al. (2003) Magnetic resonance spectroscopic pharmacodynamic markers of the heat shock protein 90 inhibitor 17-allylamino,17-demethoxygeldanamycin (17AAG) in human colon cancer models. J Natl Cancer Inst 95: 1624-1633.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1624-1633
    • Chung, Y.L.1    Troy, H.2    Banerji, U.3    Jackson, L.E.4    Walton, M.I.5
  • 26
    • 27844601569 scopus 로고    scopus 로고
    • Metabolite changes in HT-29 xenograft tumors following HIF-1α inhibition with PX-478 as studied by MR spectroscopy in vivo and ex vivo
    • Jordan BF, Black K, Robey IF, Runquist M, Powis G, et al. (2005) Metabolite changes in HT-29 xenograft tumors following HIF-1α inhibition with PX-478 as studied by MR spectroscopy in vivo and ex vivo. NMR Biomed 18: 439.
    • (2005) NMR Biomed , vol.18 , pp. 439
    • Jordan, B.F.1    Black, K.2    Robey, I.F.3    Runquist, M.4    Powis, G.5
  • 27
    • 70449411170 scopus 로고    scopus 로고
    • Proton MRS detects Metabolic Changes in Hormone Sensitive and Resistant Human Prostate Cancer Model CWR22 and CWR22r
    • Le HC, Lupu M, Kotedia K, Rosen N, Solit D, et al. (2009) Proton MRS detects Metabolic Changes in Hormone Sensitive and Resistant Human Prostate Cancer Model CWR22 and CWR22r. Magn Reson Med 62: 1112-1119.
    • (2009) Magn Reson Med , vol.62 , pp. 1112-1119
    • Le, H.C.1    Lupu, M.2    Kotedia, K.3    Rosen, N.4    Solit, D.5
  • 28
    • 72949106484 scopus 로고    scopus 로고
    • Nuclear magnetic resonance detects phosphoinositide 3-Kinase/Akt-independent traits common to pluripotent murine embryonic stem cells and their malignant counterparts
    • Romanska HM, Tiziani S, Howe RC, Gunther UL, Guizar Z, et al. (2009) Nuclear magnetic resonance detects phosphoinositide 3-Kinase/Akt-independent traits common to pluripotent murine embryonic stem cells and their malignant counterparts. Neoplasia 11: 1301-1308.
    • (2009) Neoplasia , vol.11 , pp. 1301-1308
    • Romanska, H.M.1    Tiziani, S.2    Howe, R.C.3    Gunther, U.L.4    Guizar, Z.5
  • 29
    • 0035793795 scopus 로고    scopus 로고
    • Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells
    • Ronen SM, Jackson LE, Beloueche M, Leach MO, (2001) Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells. Br J Cancer 84: 691-696.
    • (2001) Br J Cancer , vol.84 , pp. 691-696
    • Ronen, S.M.1    Jackson, L.E.2    Beloueche, M.3    Leach, M.O.4
  • 30
    • 55749084732 scopus 로고    scopus 로고
    • Monitoring histone deacetylase inhibition in vivo: Noninvasive magnetic resonance spectroscopy method
    • Sankaranarayanapillai M, Tong WP, Yuan Q, Bankson JA, Dafni H, et al. (2008) Monitoring histone deacetylase inhibition in vivo: Noninvasive magnetic resonance spectroscopy method. Mol Imaging 7: 92-100.
    • (2008) Mol Imaging , vol.7 , pp. 92-100
    • Sankaranarayanapillai, M.1    Tong, W.P.2    Yuan, Q.3    Bankson, J.A.4    Dafni, H.5
  • 31
    • 77956004085 scopus 로고    scopus 로고
    • Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma
    • Koul D, Shen R, Kim YW, Kondo Y, Lu Y, et al. (2010) Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma. Neuro Oncology 12: 559-569.
    • (2010) Neuro Oncology , vol.12 , pp. 559-569
    • Koul, D.1    Shen, R.2    Kim, Y.W.3    Kondo, Y.4    Lu, Y.5
  • 32
    • 0042885973 scopus 로고    scopus 로고
    • The Hsp90 chaperone complex as a novel target for cancer therapy
    • Goetz MP, Toft DO, Ames MM, Erlichman C, (2003) The Hsp90 chaperone complex as a novel target for cancer therapy. Annals of Oncology 14: 1169-1176.
    • (2003) Annals of Oncology , vol.14 , pp. 1169-1176
    • Goetz, M.P.1    Toft, D.O.2    Ames, M.M.3    Erlichman, C.4
  • 33
    • 33646198860 scopus 로고    scopus 로고
    • Pharmaco-metabonomic phenotyping and personalized drug treatment
    • Clayton AT, Lindon JC, Cloarec O, Antti H, Charuel C, et al. (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature 440: 1073-1077.
    • (2006) Nature , vol.440 , pp. 1073-1077
    • Clayton, A.T.1    Lindon, J.C.2    Cloarec, O.3    Antti, H.4    Charuel, C.5
  • 34
    • 43749087841 scopus 로고    scopus 로고
    • Human metabolic phenotype diversity and its association with diet and blood pressure
    • Holmes E, Loo RL, Stamler J, Bictash M, Yap IKS, et al. (2008) Human metabolic phenotype diversity and its association with diet and blood pressure. Nature 453: 396-400.
    • (2008) Nature , vol.453 , pp. 396-400
    • Holmes, E.1    Loo, R.L.2    Stamler, J.3    Bictash, M.4    Yap, I.K.S.5
  • 35
    • 62549138339 scopus 로고    scopus 로고
    • Early stage diagnosis of oral cancer using 1H-NMR-based metabolomics
    • Tiziani S, Lopes V, Günther UL, (2009) Early stage diagnosis of oral cancer using 1H-NMR-based metabolomics. Neoplasia 11: 269-276.
    • (2009) Neoplasia , vol.11 , pp. 269-276
    • Tiziani, S.1    Lopes, V.2    Günther, U.L.3
  • 36
    • 36248980949 scopus 로고    scopus 로고
    • H-1 MRS identifies specific metabolite profiles associated with MYCN-amplified and non-amplified tumour subtypes of neuroblastoma cell lines
    • Peet AC, McConville C, Wilson M, Levine BA, Reed M, et al. (2007) H-1 MRS identifies specific metabolite profiles associated with MYCN-amplified and non-amplified tumour subtypes of neuroblastoma cell lines. NMR Biomed 20: 692-700.
    • (2007) NMR Biomed , vol.20 , pp. 692-700
    • Peet, A.C.1    McConville, C.2    Wilson, M.3    Levine, B.A.4    Reed, M.5
  • 37
    • 64249158872 scopus 로고    scopus 로고
    • Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines
    • Tiziani S, Lodi A, Khanim FL, Viant MR, Bunce CM, et al. (2009) Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines. PLoS One 4: e4251.
    • (2009) PLoS One , vol.4
    • Tiziani, S.1    Lodi, A.2    Khanim, F.L.3    Viant, M.R.4    Bunce, C.M.5
  • 38
    • 79951879368 scopus 로고    scopus 로고
    • Hypoxia triggers major metabolic changes in AML cells without altering indomethacin-induced TCA cycle deregulation
    • Lodi A, Tiziani S, Khanim FL, Drayson MT, Günther UL, et al. (2011) Hypoxia triggers major metabolic changes in AML cells without altering indomethacin-induced TCA cycle deregulation. ACS Chem Biol 6: 169-175.
    • (2011) ACS Chem Biol , vol.6 , pp. 169-175
    • Lodi, A.1    Tiziani, S.2    Khanim, F.L.3    Drayson, M.T.4    Günther, U.L.5
  • 39
    • 34447639457 scopus 로고    scopus 로고
    • MR-determined metabolic phenotype of breast cancer in prediction of lymphatic spread, grade, and hormone status
    • Bathen TF, Jensen LR, Sitter B, Fjoesne HE, Halgunset J, et al. (2007) MR-determined metabolic phenotype of breast cancer in prediction of lymphatic spread, grade, and hormone status. Breast Cancer Res Treat 104: 181-189.
    • (2007) Breast Cancer Res Treat , vol.104 , pp. 181-189
    • Bathen, T.F.1    Jensen, L.R.2    Sitter, B.3    Fjoesne, H.E.4    Halgunset, J.5
  • 40
    • 77956286242 scopus 로고    scopus 로고
    • Magnetic resonance metabolomics of intact tissue: a biotechnological tool in cancer diagnostics and treatment evaluation
    • Bathen TF, Sitter B, Sjobakk TE, Tessem MB, Gribbestad IS, (2010) Magnetic resonance metabolomics of intact tissue: a biotechnological tool in cancer diagnostics and treatment evaluation. Cancer Res 70: 6692-6696.
    • (2010) Cancer Res , vol.70 , pp. 6692-6696
    • Bathen, T.F.1    Sitter, B.2    Sjobakk, T.E.3    Tessem, M.B.4    Gribbestad, I.S.5
  • 41
    • 60849139445 scopus 로고    scopus 로고
    • Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS)
    • Chan ECY, Koh PK, Mal M, Cheah PY, Eu KW, et al. (2009) Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS). J Proteome Res 8: 352-361.
    • (2009) J Proteome Res , vol.8 , pp. 352-361
    • Chan, E.C.Y.1    Koh, P.K.2    Mal, M.3    Cheah, P.Y.4    Eu, K.W.5
  • 42
    • 17144387912 scopus 로고    scopus 로고
    • Metabolic characterization of human prostate cancer with tissue magnetic resonance spectroscopy
    • Cheng LL, Burns MA, Taylor JL, He WL, Halpern EF, et al. (2005) Metabolic characterization of human prostate cancer with tissue magnetic resonance spectroscopy. Cancer Res 65: 3030-3034.
    • (2005) Cancer Res , vol.65 , pp. 3030-3034
    • Cheng, L.L.1    Burns, M.A.2    Taylor, J.L.3    He, W.L.4    Halpern, E.F.5
  • 44
    • 33847378349 scopus 로고    scopus 로고
    • NMR-based metabonomics in toxicology research
    • In: Vaidyanathan S, Harrigan GG, Goodacre RE, editors, Strategies for Systems Biology. Springer
    • Schnackenberg LK, Beger RD, Dragan YP, (2009) NMR-based metabonomics in toxicology research In: Vaidyanathan S, Harrigan GG, Goodacre RE, editors. Metabolome Analyses pp. 159-172 Strategies for Systems Biology. Springer.
    • (2009) Metabolome Analyses , pp. 159-172
    • Schnackenberg, L.K.1    Beger, R.D.2    Dragan, Y.P.3
  • 46
    • 26944439006 scopus 로고    scopus 로고
    • A Phase II Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Hormone-Refractory Metastatic Prostate Cancer
    • Heath EI, Gaskins M, Pitot HC, Pili R, Tan W, et al. (2005) A Phase II Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Hormone-Refractory Metastatic Prostate Cancer. Clinical Prostate Cancer 4: 138-141.
    • (2005) Clinical Prostate Cancer , vol.4 , pp. 138-141
    • Heath, E.I.1    Gaskins, M.2    Pitot, H.C.3    Pili, R.4    Tan, W.5
  • 47
    • 34250197902 scopus 로고    scopus 로고
    • Phase I Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Advanced Cancer
    • Solit DB, Ivy SP, Kopil C, Sikorski R, Morris MJ, et al. (2007) Phase I Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Advanced Cancer. Clinical Cancer Research 13: 1775-1782.
    • (2007) Clinical Cancer Research , vol.13 , pp. 1775-1782
    • Solit, D.B.1    Ivy, S.P.2    Kopil, C.3    Sikorski, R.4    Morris, M.J.5
  • 48
    • 84855983451 scopus 로고    scopus 로고
    • Metabolic Consequences of PI3K/AKT signaling in MCF-7 Breast Cancer Cells
    • doi: 10.1002/nbm.1764
    • Su JS, Woods SM, Ronen SM, (2011) Metabolic Consequences of PI3K/AKT signaling in MCF-7 Breast Cancer Cells. NMR Biomed doi:10.1002/nbm.1764.
    • (2011) NMR Biomed
    • Su, J.S.1    Woods, S.M.2    Ronen, S.M.3
  • 50
    • 23644448721 scopus 로고    scopus 로고
    • HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
    • Isaacs JS, Jung YJ, Mole DR, Lee S, Torres-Cabala C, et al. (2005) HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability. Cancer cell 8: 143-153.
    • (2005) Cancer Cell , vol.8 , pp. 143-153
    • Isaacs, J.S.1    Jung, Y.J.2    Mole, D.R.3    Lee, S.4    Torres-Cabala, C.5
  • 51
    • 64749116346 scopus 로고    scopus 로고
    • c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
    • Gao P, Tchernyshyov I, Chang T-C, Lee Y-S, Kita K, et al. (2009) c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature 458: 762-765.
    • (2009) Nature , vol.458 , pp. 762-765
    • Gao, P.1    Tchernyshyov, I.2    Chang, T.-C.3    Lee, Y.-S.4    Kita, K.5
  • 52
    • 78650829442 scopus 로고    scopus 로고
    • Hsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma
    • Regan PL, Jacobs J, Wang G, Torres J, Edo R, et al. (2011) Hsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma. Int J Oncol 38: 105-112.
    • (2011) Int J Oncol , vol.38 , pp. 105-112
    • Regan, P.L.1    Jacobs, J.2    Wang, G.3    Torres, J.4    Edo, R.5
  • 53
    • 57749088701 scopus 로고    scopus 로고
    • Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
    • Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang X-Y, et al. (2008) Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. Proc Natl Acad Sci USA 105: 18782-18787.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 18782-18787
    • Wise, D.R.1    DeBerardinis, R.J.2    Mancuso, A.3    Sayed, N.4    Zhang, X.-Y.5
  • 54
    • 84856022838 scopus 로고    scopus 로고
    • Predicting long-term survival and treatment response in breast cancer patients receiving neoadjuvant chemotherapy by MR metabolic profiling
    • doi:10.1002/nbm.1762
    • Cao MD, Sitter B, Bathen TF, Bofin A, Lønning PE, et al. (2011) Predicting long-term survival and treatment response in breast cancer patients receiving neoadjuvant chemotherapy by MR metabolic profiling. NMR Biomed doi:10.1002/nbm.1762.
    • (2011) NMR Biomed
    • Cao, M.D.1    Sitter, B.2    Bathen, T.F.3    Bofin, A.4    Lønning, P.E.5
  • 55
    • 78649376401 scopus 로고    scopus 로고
    • The INTERPRET Decision-Support System version 3.0 for evaluation of Magnetic Resonance Spectroscopy data from human brain tumours and other abnormal brain masses
    • Perez-Ruiz A, Julia-Sape M, Mercadal G, Olier I, Majos C, et al. (2010) The INTERPRET Decision-Support System version 3.0 for evaluation of Magnetic Resonance Spectroscopy data from human brain tumours and other abnormal brain masses. BMC Bioinformatics 11: 581.
    • (2010) BMC Bioinformatics , vol.11 , pp. 581
    • Perez-Ruiz, A.1    Julia-Sape, M.2    Mercadal, G.3    Olier, I.4    Majos, C.5
  • 56
    • 33745402707 scopus 로고    scopus 로고
    • Development of a decision support system for diagnosis and grading of brain tumours using in vivo magnetic resonance single voxel spectra
    • Tate AR, Underwood J, Acosta DM, Julià-Sapé M, Majós C, et al. (2006) Development of a decision support system for diagnosis and grading of brain tumours using in vivo magnetic resonance single voxel spectra. NMR Biomed 19: 411-434.
    • (2006) NMR Biomed , vol.19 , pp. 411-434
    • Tate, A.R.1    Underwood, J.2    Acosta, D.M.3    Julià-Sapé, M.4    Majós, C.5
  • 57
    • 79960698472 scopus 로고
    • Water suppression that works - Excitation sculpting using arbitrary wave-forms and pulsed-field gradients
    • Hwang TL, Shaka AJ, (1995) Water suppression that works- Excitation sculpting using arbitrary wave-forms and pulsed-field gradients. J Magn Reson 112: 275-279.
    • (1995) J Magn Reson , vol.112 , pp. 275-279
    • Hwang, T.L.1    Shaka, A.J.2
  • 58
    • 0347269282 scopus 로고    scopus 로고
    • NMRLAB - Advanced NMR data processing in MATLAB
    • Günther UL, Ludwig C, Ruterjans H, (2000) NMRLAB- Advanced NMR data processing in MATLAB. J Magn Reson 145: 201-208.
    • (2000) J Magn Reson , vol.145 , pp. 201-208
    • Günther, U.L.1    Ludwig, C.2    Ruterjans, H.3
  • 59
    • 33745728718 scopus 로고    scopus 로고
    • Probabilistic quotient normalization as robust method to account for dilution of complex biological mixtures. Application in H-1 NMR metabonomics
    • Dieterle F, Ross A, Schlotterbeck G, Senn H, (2006) Probabilistic quotient normalization as robust method to account for dilution of complex biological mixtures. Application in H-1 NMR metabonomics. Anal Chem 78: 4281-4290.
    • (2006) Anal Chem , vol.78 , pp. 4281-4290
    • Dieterle, F.1    Ross, A.2    Schlotterbeck, G.3    Senn, H.4
  • 60
    • 34548490763 scopus 로고    scopus 로고
    • Improved classification accuracy in 1-and 2-dimensional NMR metabolomics data using the variance stabilising generalised logarithm transformation
    • Parsons HM, Ludwig C, Günther UL, Viant MR, (2007) Improved classification accuracy in 1-and 2-dimensional NMR metabolomics data using the variance stabilising generalised logarithm transformation. BMC Bioinformatics 8: 234.
    • (2007) BMC Bioinformatics , vol.8 , pp. 234
    • Parsons, H.M.1    Ludwig, C.2    Günther, U.L.3    Viant, M.R.4


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